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| 1 | Associations of sense of coherence with psychological distress and quality of life in inflammatory bowel disease显示文摘AIM:To investigate the relationship between sense of coherence,psychological distress and health related quality of life in inflammatory bowel disease(IBD).METHODS:This cross-sectional study enrolled a consecutive sample of 147 IBD(aged 45.1 ± 14.1 years; 57.1% female) patients recruited from a tertiary gastroenterology service.Sixty-four participants met diagnostic criteria for Crohn's disease,while eightythree patients had ulcerative colitis.Socio-demographic data(education,age,race,gender,gross monthly income and marital status),disease-related variables(illness activity,relapse rate in past 2 years,history of surgery and time since diagnosis),sense of coherence(Antonovsky's SOC scale),psychological distress symptoms(Hospital Anxiety and Depression Scale) and health-related quality of life(HRQo L; WHOQOLBref) were assessed.Hierarchical multiple regression analyses were performed to identify factors that are independently associated with psychological distress and HRQo L in patients with IBD and to provide indications for possible moderating or mediating effects.In addition,formal moderation and mediation analyses(Sobel tests) were performed to confirm potential moderators/mediators of the relationship between SOC,psychological distress symptoms and HRQoL.RESULTS:Lower SOC scores(std beta=-0.504; P < 0.001),female gender(std beta = 0.176; P = 0.021) and White race(std beta = 0.164; P = 0.033) were independently associated with higher levels of depressive symptoms,while lower levels of SOC(std beta =-0.438; P < 0.001) and higher relapse rate(std beta = 0.161; P = 0.033) were independently associated with more severe anxiety symptoms.A significant interaction between time since diagnosis and SOC was found with regard to the severity of depressive or anxiety symptoms,as the interaction term(time since diagnosis X SOC) had beta coefficients of-0.191(P = 0.009) and-0.172(P = 0.026),respectively.Lower levels of anxiety symptoms(std beta =-0.369; P < 0.001),higher levels of SOC(std beta = 0.231; P = 0.016) and non-White race(std beta =-0.229; P = 0.006),i.e.,mixed-race,which represented the reference category,were independently associated with higher levels of overall HRQoL.Anxiety symptoms were the most potent independent correlate of most aspects of HRQoL.In addition,anxiety mediated the association between SOC and satisfaction with health,as well as its relationship with physical,mental,and social relations HRQo L.Depressive symptoms also mediated the association between SOC and mental HRQoL.CONCLUSION:Our data indicated that SOC is an important construct,as it influences psychological distress and has significant albeit indirect effects on several HRQoL domains in IBD. | Thiago H Freitas Elias Andreoulakis Gilberto S Alves Hesley LL Miranda Lúcia LBC Braga Thomas Hyphantis André F Carvalho | 2015 | World Journal of Gastroenterology2015，21，21： | 10 |
| 2 | Morbidity and mortality in compensated cirrhosis type C: A retrospective follow-up study of 384 patients显示文摘 | G Fattovich G Giustina F Degos F Tremolada G Diodati P Almasio F Nevens A Solinas D Mura JT Brouwer H Thomas C Njapoum C Casarin P Bonetti P Fuschi J Basho A Tocco A Bhalla R Galassini F Noventa SW Schalm G Realdi | 1997 | Gastroenterology1997，，2： | 2 |
| 3 | Statin induction of liver fatty acid-binding protein(L-FABP)gene expression is peroxisome proliferator-activated receptor-alpha-dependent显示文摘 | Landrier JF Thomas C Grober J Duez H Percevault F Souidi M | 2004 | J Biol Chem2004，279，45： | 1 |
| 4 | Thomashow components of the Arabidopsis C repeat/dehydration responsive element bindingfactor cold-response pathway are conserved in Brassica napus and other plant species显示文摘 | KIRSTEN R J SUSANNE K KEENAN L A XIN Z VOLKER H JAMES Z Z THOMAS D MICHAEL F | 2001 | Plant Plzysiology2001，127，3： | 1 |
| 5 | Effect of ascorbic acid on health and morphology of bovine preantral follicles during longterm culture显示文摘 | Thomas F H Leask R Srsen V | 2001 | Reproduction2001，122，3： | 1 |
| 6 | Cryosurgical ablation of liver tumors in colon cancer patients increases the serum total ganglioside level and then selectively augments antiganglioside IgM显示文摘 | Mepur H Ravindranath Thomas F Wood Daniel Soh Alexandra Gonzales Sakunthala Muthugounder Carlos Perez Donald L Morton Anton J Bilchik | 2002 | Cryobiology2002，，1： | 1 |
| 7 | Burden to others and the terminally ill显示文摘 | Chochinov H M Linda J Thomas F | | J Pain Symptom Manage0，34，5： | 1 |
| 8 | Un- steady plasma actuator for separation control of low- pressure turbine blades 显示文摘 | HUANG J H CORKE T C THOMAS F O | 2006 | AIAA Journal2006，44，7： | 1 |
| 9 | Unsteady plasma actuators for separation control of low-pressure turbine blades显示文摘 | Huang J H Corke T C Thomas F O | 2006 | AIAA Journal2006，44，7： | 1 |
| 10 | Imaging of giant Meckel's diverticulum in a young adult显示文摘 | Scheraga J L Feiglin D H Thomas F D | | 0，，： | 1 |
| 11 | Trailing Edge Noise Prediction From Measured Pressures显示文摘 | Brooks Thomas F Hodgson T H | | 0，，01： | 1 |
| 12 | On the mechanism of unsteady shock oscillation in shock wave/ turbulent boundary layer interactions 显示文摘 | THOMAS F O PUTNAM C M CHU H C | 1994 | Experiments in Fluids1994，，18： | 1 |
| 13 | Taxonomic mental models in competitor definition显示文摘 | PORAC J F THOMAS H | 1990 | Academy of management review1990，15，2： | 1 |
| 14 | A review of processes and tecnologies for the recycling of lithium-ion secondary batteries显示文摘 | XU J Q THOMAS H R ROB W F | 2008 | Power Sources2008，，177： | 1 |
| 15 | Use of leukocyte poor blood components and HLA match platelet donors to prevent HLA alloimmunization显示文摘 | MURPHY M F METCALFE p THOMAS H | 1986 | Br J Hematol1986，62，3： | 1 |
| 16 | Characterization of Near-Source Ground Motions with Earthquake Simulations显示文摘 | Aagaad Brad T Hall John F Heaton Thomas H | 2001 | Earthquake Spectra2001，17，2： | 1 |
| 17 | Seasonal changes in the respiratory electron transport system (ETS) and respiration of the zebra mussel,Dreissena polymorpha in Saginaw Bay?Lake Huron显示文摘 | DAVID L F THOMAS F N THOMAS H J | 2001 | Hydrobiologia2001，448，： | 1 |
| 18 | Isolation of Angiopoietin-1, a Ligand for the TIE2 Receptor, by Secretion-Trap Expression Cloning显示文摘 | Samuel Davis Thomas H Aldrich Pamela F Jones Ann Acheson Debra L Compton Vivek Jain Terence E Ryan Joanne Bruno Czeslaw Radziejewski Peter C Maisonpierre George D Yancopoulos | 1996 | Cell1996，，7： | 1 |
| 19 | Competitive groups as cognitive communities: The case of Scottish knitwear manufacturers显示文摘 | Porac J F Thomas H Baden-Fuller C | 1989 | Journal of Management Studies1989，26，4： | 1 |
| 20 | Resistance to bovine respiratory syncytial virus (BRSV) induced in calves by a recombinant bovine herpesvirus-1 expressing the attachment glycoprotein ofBRSV 显示文摘 | Taylor G Rijsewijk F A M Thomas L H | 1998 | J Gen Virol1998，79，： | 1 |
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