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| 1 | 化感作用与杂草治理显示文摘本文摘译自《Weed-Crop Ecology》(North Scituate,Massachusetts:Breton Publishers)一书。较早而系统地介绍了植物的化感作用,以充分发挥其对杂草综合治理方面的应用价值。 | Aldrich R J 马晓渊(摘译) | 2011 | 杂草科学2011，29，4： | 9 |
| 2 | Optimizing control of coal flotation by neuro-immune algorithm显示文摘Coal flotation is widely used to separate commercially valuable coal from the fine ore slurry, and is an industrial process with nonlinear, multivariable, time-varying and long time-delay characteristics. The online detection of ash content of products as the operation performance evaluation in the flotation system is extraordinarily difficult because of the low solid content and numerous micro-bubbles in the slurry. Moreover, it is time-consuming by manual analysis. Consequently, the optimal separation is not usually maintained. A novel technique, called the neuro-immune algorithm (NIA) inspired by the biological nervous and immune systems, is presented in this paper for predicting the ash content of clean coal and performing the optimizing control to the coal flotation system. The proposed algorithm integrates the deeply-studied artificial neural network (ANN) and the developing artificial immune system (AIS). A two-layer back-propagation network was constructed offline based on the historical process data under the best system situation, using five parameters: the flow and the density of raw slurry, the input flows of water, the kerosene and the GF oil, as the inputs and the ash content of clean coal as the output. The immune cell of AIS is made up of six parameters above as the antigen. The cytokine based clone selection algorithm is used to produce the relative antibody. The detailed computation procedures about the hybrid neuro-immune algorithm are minutely discussed. The ash content of clean coal was predicted by NIA using the practical process data s: (308.6 174.7 146.1 43.6 4.0 9.4), and the absolute difference between the actual and computed ash content values was 0.0967%. The optimizing control on NIA was simulated considering two different situations where the ash content of clean coal was controlled downward from 10.00% or upward from 9.20% predicted by ANN to the target value 9.50%. The results indicate that the target ash content and the value of controlling parameters are obtained after several control cycles. | Yang Xiaoping Chris Aldrich | 2013 | International Journal of Mining Science and Technology2013，23，3： | 3 |
| 3 | Isolation of angiopoietin-1,a ligand for the TIE2 receptor,by secretion-trap expression cloning 显示文摘 | David S Aldrich T H Johes P F | 1996 | Cell1996，87，7： | 2 |
| 4 | Preclinical characterization and validation of a dual-labeled trastuzumab-based imaging agent for diagnosing breast cancer显示文摘Objective: The combination of both nuclear and fluorescent reporters provides unique opportunities for noninvasive nuclear imaging with subsequent fluorescence image-guided resection and pathology. Our objective was to synthesize and optimize a dual-labeled trastuzumab-based imaging agent that can be used to validate an optical imaging agent with potential use in identifying tumor metastases in human epidermal growth factor receptor 2(HER2) positive breast cancer patients.Methods: [111In]-DTPA-trastuzumab-IRDye 800 was synthesized by a three-step procedure. Purity, stability, immunoreactivity, internalization and biodistribution were explored in HER2+ SKBR-3 cells. Biodistribution of [111In]-DTPA-trastuzumab-IRDye 800 was performed in a SKBR-3 xenograft model.Results: [111In]-DTPA-trastuzumab-IRDye 800 demonstrated high purity by both chemical and fluorometric determinations. Both flow cytometry and the Lindmo assay demonstrated a high binding affinity of [111In]-DTPA-trastuzumab-IRDye 800 to HER2-overexpressing cells. The dual-labeled conjugate was stable in PBS, but not in serum after 24 h at 37 ℃. Larger molecules(>150 k D) were seen after a 24 h-incubation in human serum. Biodistribution studies revealed tumor-specific accumulation of [111In]-DTPAtrastuzumab-IRDye 800 in SKBR-3 tumors, and tumor uptakes at 24 and 48 h were(12.42±1.72)% and(9.96±1.05)%, respectively, following intravenous administration. The tumor-to-muscle ratio was 9.13±1.68 at 24 h, and increased to 12.79±2.13 at 48 h. Liver and kidney showed marked uptake of the dual-labeled imaging agent.Conclusions: [111In]-DTPA-trastuzumab-IRDye 800 is an effective diagnostic biomarker that can be used to validate dual-labeled, molecularly targeted imaging agents and can allow these agents to be translated into clinical practice for identifying HER2+ lesions. | Xuejuan Wang Melissa B. Aldrich Milton V. Marshall Eva M. Sevick-Muraca | 2015 | Chinese Journal of Cancer Research2015，27，1： | 2 |
| 5 | Cytokines are systemic effectors of lymphatic function in acute inflammation显示文摘 | Melissa B. Aldrich Eva M. Sevick-Muraca | 2013 | Cytokine2013，，： | 2 |
| 6 | The significance of flotation froth appearance for machine vision control显示文摘 | D.W. Moolman J.J. Eksteen C. Aldrich J.S.J. van Deventer | 1996 | International Journal of Mineral Processing1996，，3： | 2 |
| 7 | Adsorption of heavy metals by biomaterials derived from the marine alga Ecklonia maxima显示文摘 | D Feng C Aldrich | 2004 | Hydrometallurgy2004，，1： | 2 |
| 8 | When can the patient with deep venous thrombosis begin to ambulate? 显示文摘 | Aldrich D Hunt DP | 2004 | Phys Tber2004，84，3： | 1 |
| 9 | Semi-metallics:a new type of friction material显示文摘 | | | SAE Paper0，1971，： | 1 |
| 10 | Enhanced transduction of mouse bone marrow-derived dendritic cells by repetitive infection with self-complementary adeno-associated virus 6 combined with immunostimulatory ligands显示文摘 | Aldrich WA Ren C White AF | 2006 | Gene Ther2006，13，1： | 1 |
| 11 | The interrelationship between surface froth characteristics and industrial flotation performance显示文摘 | MOOLMAN D W ALDRICH C SCHMITZ G P J | 1996 | Minerals Engineering1996，9，8： | 1 |
| 12 | A simple method of assessing the temporomandibular joint with helical computed tomography:technical note显示文摘 | Aldrich JE Forster BB Wong K | 1999 | Canadian Association of Radiologists Journal1999，50，2： | 1 |
| 13 | The classification of froth structures in a copper flotation plant by means of a neural net 显示文摘 | Moolman D W Aldrich C van Deventer J S J | 1995 | Int J Miner Process1995，43，： | 1 |
| 14 | Responses of young almond trees to late-season drought 显示文摘 | Fereres E Aldrich T M Schulbaeh H | 1981 | California Agriculture1981，35，78： | 1 |
| 15 | Experi- ence with an automated point - of - use unit - dose drug distribution sytem显示文摘 | Ray MD Aldrich LT Lew PJ | 1995 | Hosp Pharm1995，30，1： | 1 |
| 16 | The significance of Flotation Froth Appearance for Machine Vision Control 显示文摘 | Moolman D W Eksteen J J Aldrich C | 1996 | Journal of miner al Processing1996，48，： | 1 |
| 17 | The application of neural nets in the metallurgical industry显示文摘 | Aldrich C Reuter M A | 1994 | Miner Eng1994，7，： | 1 |
| 18 | Even Dwarfs Started Small: Liabilities of ABe and Size and Their Strategic Implications 显示文摘 | Aldrich H Auster E R | 1986 | Research in organizational behavior1986，8，1986： | 1 |
| 19 | Olfactory reception of potential pheromones and plant odors by tarnished plant bug, Lygus lineolaris (Hemiptera: Miridae)显示文摘 | Chinta S Dickens J C Aldrich J R | 1994 | Journal of Chemical Ecology1994，20，： | 1 |
| 20 | Adenovims-based gene therapy during clevudine treatment of woodehucks chronically infected with woodchuck hepatitis virus显示文摘 | Zhu Y Cullen JM Aldrich CE | 2004 | Virology2004，327，1： | 1 |
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