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| 1 | Effects of ammonia exposure on carcass traits and fatty acid composition of broiler meat显示文摘We aimed to study the effects of ammonia on carcass traits, organ indices and fatty acid composition of broilers. Four hundred 21-d-old male Arbor Acres broilers with initial weight 563.52 ± 2.82 g were randomly allotted to 1 of 4 groups treated with ammonia at <3 mg/kg(control),25 ± 3. 50 ± 3, and75 ± 3 mg/kg concentrations. Each group consisted of 4 replicates of 25 birds. Broilers from 21 to 42 d were reared on the net floor in the respiration-metabolism chambers where similar environmental conditions were maintained. At 32 and 42 d of age, carcass traits and organ indices were determined for4 birds per pen. At 42 d of age, fatty acid composition in the breast and thigh muscle of broilers was measured. Results showed as follows: 1) At 32 d, the dressing percentage of broilers exposed to 25 and75 mg/kg ammonia were lower than those in the control group(P < 0.05); eviscerated yield percentage of broilers in the 25 mg/kg ammonia group was also lower(P < 0.05). At 42 d, the dressing percentage of broilers in the ammonia treatments and the thigh muscle percentage of broilers in the 50 and 75 mg/kg ammonia groups were lower(P < 0.05) than those in the control. Breast muscle percentage of broilers exposed to 25 and 50 mg/kg ammonia and eviscerated yield percentage exposed to 50 mg/kg ammonia were lower than those in the control(P < 0.05). 2) The kidney index of broilers(d 32) exposed to ammonia was greater(P < 0.05) than that of the control. At 42 d, hepatic index of broilers exposed to ammonia was increased(P < 0.05), and spleen index was decreased(P < 0.05). 3) At 42 d, stearic(C18:0)and saturated fatty acids(SFA) in the thigh muscle of broilers were higher, while the unsaturated fatty acid:saturated fatty acid(U:F) ratio and unsaturated fatty acid(UFA) were lower in the 50 mg/kg ammonia treatment than in the control group(P < 0.05). In conclusion, ammonia over 25 mg/kg could decline carcass traits and immune organ indices and increase the kidney and hepatic indices. Further,exposure to 50 mg/kg ammonia could also decrease breast and thigh muscle yield percentage while increasing SFA content and decreasing UFA content in the thigh muscle of broilers. | Huan Xing Sujun Luan Yongbo Sun Renna Sa Hongfu Zhang | 2016 | Animal Nutrition2016，，4： | 8 |
| 2 | Optimization on conventional and electric air-cycle refrigeration systems of aircraft: A short-cut method and analysis显示文摘The air-cycle refrigeration system is widely used in commercial and military aircraft,and its efficiency greatly affects aircraft performance.Nowadays,this system requires a more efficient design and optimization method.In this paper,a short-cut optimization method with high efficiency and effectiveness is introduced for both conventional and electric air-cycle refrigeration systems.Based on the system characteristics,a four-layer parameter matching algorithm is designed which avoids computational difficulty caused by simultaneous equations.Fuel penalty is chosen as the objective function of optimization;design variables are reduced based on sensitivity analysis to improve optimization efficiency.The results show that the 3-variable optimization of the conventional air-cycle refrigeration system can obtain almost the same results as the traditional 6-variable optimization in that these two optimizations can both significantly reduce the fuel penalty.However,the computer running time of the 3-variable optimization is much shorter than that of the 6-variable optimization.The optimal fuel penalty of the electric air-cycle refrigeration system is lower than that of the conventional one.This study can provide reference for optimizing the aircycle refrigeration system of aircraft. | Hongsheng JIANG Sujun DONG Hainan ZHANG Fengming AI Zhiwei ZHANG Jun WANG | 2020 | Chinese Journal of Aeronautics2020，33，7： | 6 |
| 3 | Global features and trends of the tropopause derived from GPS/CHAMP RO data显示文摘The global characteristics and trends of the tropopause physical parameters,height and temperature,obtained from the GPS/CHAMP radio occultation(RO) data in the period from Jul.2001 to Oct.2008,were modeled and analyzed in this work.The global distribution and variation of these parameters with latitude were estimated and analyzed using the Empirical Orthogonal Function(EOF),which was introduced to reveal the possible relationship between the tropopause variations and global climate change.The tropopause height and temperature varied with latitude.The results obtained by using the Empirical Orthogonal Function analysis suggested a recent rise in tropopause height and decrease in tropopause temperature;and also partly supported the argument that the global rise in the tropopause is consistent with global climate change.These results also revealed that the tropopause height increased mainly in the Polar regions,particularly in the South Polar region,as well as the regions where human activity is relatively significant,and decreased in the areas that are sparsely populated or have less human activity,such as the tropic region and south hemisphere.This paper also confirms that the GPS/LEO RO data are more reliable and can be effectively used to analyze the tropopause physical parameters. | HAN TingTing PING JinSong ZHANG SuJun | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，2： | 4 |
| 4 | Haploidentical hematopoietic cell transplantation for severe acquired aplastic anemia: a case-control study of post-transplant cyclophosphamide included regimen vs. anti-thymocyte globulin & colony-stimulating factor-based regimen显示文摘Dear Editor,Haploidentical allogeneic hematopoietic stem cell transplantation(haplo-HSCT),a curative therapy for severe aplastic anemia(SAA)patients,has been used clinically for decades.Two models,not involving ex vitro T-cell depletion,have been adopted for haplo-HSCT in patients with SAA.The first is referred to as the'Beijing protocol'(Xu et al.,2017),and comprises a conditioning regimen using busulfex(BU),cyclophosphamide(CY). | Lanping Xu Bin Fu Wenjing Wang Yajing Xu Depei Wu Shunqing Wang Qifa Liu Linghui Xia Sujun Gao Ming Jiang Jianmin Wang Xi Zhang Hai Bai Huiren Chen Chunfu Li Xiaojun Huang | 2020 | Science China(Life Sciences)2020，63，6： | 3 |
| 5 | 2022 Chinese expert consensus and guidelines on clinical management of toxicity in anti-CD19 chimeric antigen receptor T-cell therapy for B-cell non-Hodgkin lymphoma显示文摘Adoptive cellular immunotherapy with chimeric antigen receptor(CAR)T cells has emerged as a novel modality for treating relapsed and/or refractory B-cell non-Hodgkin lymphoma(B-NHL).With increasing approval of CAR T-cell products and advances in CAR T cell therapy,CAR T cells are expected to be used in a growing number of cases.However,CAR T-cell-associated toxicities can be severe or even fatal,thus compromising the survival benefit from this therapy.Standardizing and studying the clinical management of these toxicities are imperative.In contrast to other hematological malignancies,such as acute lymphoblastic leukemia and multiple myeloma,anti-CD19 CAR T-cell-associated toxicities in B-NHL have several distinctive features,most notably local cytokine-release syndrome(CRS).However,previously published guidelines have provided few specific recommendations for the grading and management of toxicities associated with CAR T-cell treatment for B-NHL.Consequently,we developed this consensus for the prevention,recognition,and management of these toxicities,on the basis of published literature regarding the management of anti-CD19 CAR T-cell-associated toxicities and the clinical experience of multiple Chinese institutions.This consensus refines a grading system and classification of CRS in B-NHL and corresponding measures for CRS management,and delineates comprehensive principles and exploratory recommendations for managing anti-CD19 CAR T-cell-associated toxicities in addition to CRS. | Ping Li Yang Liu Yun Liang Jian Bo Sujun Gao Yongxian Hu Yu Hu He Huang Xiaojun Huang Hongmei Jing Xiaoyan Ke Jianyong Li Yuhua Li Qifa Liu Peihua Lu Heng Mei Ting Niu Yongping Song Yuqin Song Liping Su Sanfang Tu Jianxiang Wang Depei Wu Zhao Wang Kailin Xu Zhitao Ying Qingming Yang Yajing Zhang Fengxia Shi Bin Zhang Huilai Zhang Xi Zhang Mingfeng Zhao Weili Zhao Xiangyu Zhao Liang Huang Jun Zhu Wenbin Qian Weidong Han Aibin Liang | 2023 | Cancer Biology & Medicine2023，20，2： | 3 |
| 6 | Electroluminescence performances of 1,1-bis(4-(N,N-dimethylamino)phenyl)-2,3,4,5-tetraphenylsilole based polymers in three cathode architectures显示文摘A new silole monomer with two 4-(N,N-dimethylamino)phenyl substitutions on silicon atom as designed and synthesized.Three copolymers PF-N-HPS1,PF-N-HPS10 and PF-N-HPS20 were then obtained by copolymerizations of 2,7-fluorene derivatives with the silole monomer at feed ratios of 1%,10%,and 20%.Their UV-vis absorption,electrochemical,photoluminescent,and electroluminescent (EL) properties were investigated.PF-N-HPS possessed HOMO levels of 5.25-5.58 eV,and showed green emissions.Using PF-N-HPS as the emissive layer,three different polymer light-emitting diodes were fabricated as device A with ITO/PEDOT/PF-N-HPS/Al,device B with ITO/PEDOT/PF-N-HPS/Ba/Al,and device C with ITO/PEDOT/PF-N-HPS/TPBI/Ba/Al.For the device A,PF-N-HPS only showed very low EL efficiency of 0.06-0.33 cd/A,indicating that the Al cathode could not inject electron efficiently to the emissive polymers containing the 4-(N,N-dimethylamino)phenyl groups.For the device B,low work function Ba supplied better electron injections,and the EL efficiency could be improved to 0.85-1.44 cd/A.TPBI with a deep HOMO level of 6.2 eV could enhance electron transport and hole blocking.Thus modified recombinations and largely elevated EL efficiency of 4.56-7.96 cd/A were achieved for the device C.The separation of the emissive layer and metal cathode with the TPBI layer may also suppress exciton quenching at the cathode interface. | LIU ZhiTian HU SuJun ZHANG LinHua CHEN JunWu PENG JunBiao CAO Yong | 2013 | Science China Chemistry2013，56，8： | 2 |
| 7 | A digital open-loop Doppler processing prototype for deep-space navigation显示文摘A prototype based on digital radio technology with associated open-loop Doppler signal processing techniques has been developed to measure a spacecraft's line-of-sight velocity. The prototype was tested in China's Chang'E-1 lunar mission relying on S-band telemetry signals transmitted by the sat-ellite,with results showing that the residuals had a RMS value of ~3 mm/s (1σ ) using 1-sec integration,which is consistent with the Chinese conventional USB (Unified S-Band) tracking system. Such preci-sion is mainly limited by the short-term stability of the atomic (e.g. rubidium) clock at the uplink ground station. It can also be improved with proper calibration to remove some effects of the transmission media (such as solar plasma,troposphere and ionosphere),and a longer integration time (e.g. down to 0.56 mm/s at 34 seconds) allowed by the spacecraft dynamics. The tracking accuracy can also be in-creased with differential methods that may effectively remove most of the long-term drifts and some of the short-term uncertainties of the uplink atomic clock,thereby further reducing the residuals to the 1 mm/s level. Our experimental tracking data have been used in orbit determination for Chang'E-1,while other applications (such as the upcoming YH-1 Mars orbiter) based on open-loop Doppler tracking will be initiated in the future. Successful application of the prototype to the Chang'E-1 mission in 2008 is believed to have great significance for China's future deep space exploration. | JIAN NianChuan SHANG Kun ZHANG SuJun WANG MingYuan SHI Xian PING JingSong YAN JianGuo TANG GeShi LIU JunZe QIU Shi FUNG Lai-Wo ZHANG Hua WANG Zhen GOU Wei | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，12： | 2 |
| 8 | Characteristics and performance of 10kW class all-vanadium redox-flow battery stack显示文摘 | Ping Zhao Huamin Zhang Hantao Zhou Jian Chen Sujun Gao Baolian Yi | 2006 | Journal of Power Sources2006，，2： | 2 |
| 9 | Review on the Application of Bamboo-Based Materials in Construction Engineering显示文摘Due to the continuously increasing demand for building materials across the world,it is necessary to use renewable materials in place of the existing nonrenewable materials in construction projects.Bamboo is a fast-growing flowering plant that may be used as a renewable material in construction.The use of bamboo in the construction of buildings can improve its long-term carbon fixation capacity and economic benefits.Although bamboo has the advantages of superior performance,low carbon content,high energy-saving and emission-reducing capacity,bamboo is an anisotropic material,which has many factors affecting its material performance,large variability of material performance,lack of systematic research,and the use of bamboo as the main building material is not always limited.This paper systematically summarizes the research status of bamboo as a building material from the aspects of bamboo composition,gradation,material properties,bamboo building components,connection nodes,and use of artificial boards.On this basis,some constructive suggestions are put forward for the further study of bamboo in the field of architecture. | Biqing Shu Zhongping Xiao Lu Hong Sujun Zhang Chen Li Naiqiang Fu Xiaoning Lu | 2020 | Journal of Renewable Materials2020，8，10： | 2 |
| 10 | Implementation of the Earth-based planetary radio occultation inversion technique显示文摘The planetary radio occultation technique is one of the earliest suggested and achieved methods to detect the planetary atmosphere,and has been conducted by almost every deep space planetary probe.The principles,modules,inversion results and primary analysis of the SHAO Planetary Occultation observation Processing system(SPOPs) are presented in this paper.Utilizing open-loop and closed-loop Doppler residual data of the Mars Express radio occultation experiment provided by ESA PSA and NASA PDS,the temperature,pressure,molecular number density profiles of Martian atmosphere and electron density profiles of the ionosphere are successfully retrieved,and the results are validated by the released radio science level 04 products of the ESA MaRS group.This system can also process the atmosphere radio occultation observations of other planets and theirs natural satellites.The implementation of the planetary radio occultation technique is of significance to China's YH-1 Mars exploration project,as well as for future planetary exploration missions from China. | ZHANG SuJun PING JinSong HAN TingTing MAO XiaoFei HONG ZhenJie | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，7： | 2 |
| 11 | Characteristics and performance of 10 k W class all-vanadium redox-flow battery stack显示文摘 | Zhao Ping Zhang Huamin Zhou Hantao Chen Jian Gao Sujun Yi Baolian | 2006 | Journal of Power Sources2006，162，2： | 1 |
| 12 | Anticancer activity and quantitative analysis of flavone of Cirsium japonicum DC显示文摘 | LIU Sujun ZHANG Jie LI Daxu | 2007 | Natural Product Research2007，21，10： | 1 |
| 13 | Analysis of the current situation and trends of the incidence of prostate cancer in China显示文摘 | Han Sujun Zhang Siwei Han Wanqing | 2013 | J Clin Oncol2013，18，4： | 1 |
| 14 | Role of Neu-p11/luzindole in the regulation of nsulin signaling pathways and insulin resistance显示文摘 | Xiuping Li Shichang Cai Weidong Yin Xiaobo Hu Sujun Zhang Zhengming Li Xing Li Moshe Laudon | 2016 | Acta Biochimica et Biophysica Sinica2016，48，5： | 1 |
| 15 | Oxygen vacancy and Mn2+induced ferromagnetism in Mn-doped ZnO thin films显示文摘With the purpose of investigating the origin of ferromagnetism(FM), Mn-doped Zn O thin films had been fabricated by radio frequency(rf) magnetron sputtering and subsequent anneal process. The characterization of the Mn-doped Zn O thin films was conducted by X-ray diffraction(XRD), X-ray photoelectron spectroscopy(XPS), and superconducting quantum interference device(SQUID). With increasing the anneal temperature from 300°C to 700°C for 3 min, the influence on magnetism of the Mndoped ZnO thin films is slight. While extending the anneal time from 3 to 50 min at 300°C, the influence on magnetism is obvious and the Mn-doped ZnO thin films with 30 min clearly demonstrate FM. Compared with the effect of oxygen vacancy and substitutional Mn2+on the ferromagnetic behavior, OVplays the main role in inducing FM of the Mn-doped ZnO thin films with good crystal structure. | GUAN SuJun NASU Naho ZHANG Yu TAMAMOTO Yuri YAMANOBE Maria ZHAO XinWei | 2019 | Science China(Technological Sciences)2019，62，10： | 1 |
| 16 | Experimental investigation on operating behaviors of loop heat pipe with thermoelectric cooler under acceleration conditions显示文摘An experimental study was carried out in this article to investigate the transient operating performance of a Dual Compensation Chamber Loop Heat Pipe(DCCLHP) with Thermoelectric Cooler(TEC) under acceleration conditions and ammonia was selected as the working fluid.For the purpose of comparison, experimental work was conducted under terrestrial gravity.Sensitivity analysis was performed to explore the effect of several control parameters such as the heat load, acceleration magnitude and TEC assist on the startup and operating performance of the DCCLHP.Experimental results indicate that the DCCLHP can get to a steady-state operation when the heat load changes from 25 W to 300 W under terrestrial gravity.While under acceleration conditions, the DCCLHP can work at a high operating temperature or even fail to operate, which shows the acceleration effect plays a significant impact on the loop operation.The TEC assist with power of 10 W can improve the operating performance and reduce the operating temperature for the case of small heat load and acceleration magnitude.When the acceleration exceeds 3 g at large heat load, the effect of TEC assist on the operation at large heat load can be ignored. | Yongqi XIE Xinyu LI Sujun DONG Hongxing ZHANG Hongwei WU | 2020 | Chinese Journal of Aeronautics2020，33，3： | 1 |
| 17 | Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism显示文摘 | Haoqiang Ying Alec C. Kimmelman Costas A. Lyssiotis Sujun Hua Gerald C. Chu Eliot Fletcher-Sananikone Jason W. Locasale Jaekyoung Son Hailei Zhang Jonathan L. Coloff Haiyan Yan Wei Wang Shujuan Chen Andrea Viale Hongwu Zheng Ji-hye Paik Carol Lim Alexande | 2012 | Cell2012，，3： | 1 |
| 18 | A series of energy-transfer copolymers derived from fluorene and 4,7-dithienylbenzotriazole for high efficiency yellow,orange,and white light-emitting diodes显示文摘 | Zhang Lianjie Hu Sujun Chen Junwu | 2011 | Advanced Functional Materials2011，21，19： | 1 |
| 19 | Comparative risk of acute kidney injury among cancer patients treated with immune checkpoint inhibitors显示文摘With the development and introduction of immune checkpoint inhibitors(ICIs)in cancer patients,immune-related side effects have increasingly attracted attention.However,the risks of immune-related renal toxicity are poorly characterized.In this study,we performed a network meta-analysis(NMA)of ICI-related randomized clinical trials(RCTs)to elucidate the comparative risk of acute kidney injury(AKI)in cancer patients receiving different ICIs.We also sought to identify other factors potentially affecting the risk of AKI.PubMed and EMBASE were searched for peer-reviewed trial reports published between January 2000 and May 2021.Eligible studies were RCTs studying ICIs in cancer patients and reporting AKI data.We performed a frequentist NMA to evaluate the risk ratios for grade 1-5 and grade 3-5 AKI between the treatment groups.We also assessed the absolute incidence of AKI in the ICI-containing arm using traditional direct meta-analysis.Once significant heterogeneity was detected in a traditional direct meta-analysis,multivariable meta-regression analysis was applied to identify factors that significantly affected the absolute incidence of AKI.A total of 85 RCTs were included in this study.In the NMA for the risk of grade 1-5 and 3-5 AKI,ipilimumab showed a significantly higher risk than avelumab and durvalumab,whereas 1 mg/kg nivolumab plus 3 mg/kg ipilimumab(N1I3)showed a significantly higher risk than other groups.In terms of treatment ranking,durvalumab±low-dose tremelimumab and avelumab were consistently among the top three safest treatments for grade 1-5 or 3-5 AKI,whereas N1I3,ipilimumab and tremelimumab were consistently among the top three treatments with the highest risk for grade 1-5 or 3-5 AKI.Compared with other cancers,renal cell carcinoma and urothelial carcinoma showed a significantly higher risk of AKI.The incidence of AKI was significantly higher with ICI+chemotherapy than with ICI monotherapy.In this NMA involving largescale up-to-date ICI trials,we demonstrated the comparative safety of existing ICI drugs for grade 1-5 and grade 3-5 AKI.Based on data from the ICI arms of these trials,we also revealed several potential risk factors for immune-related AKI,including tumor type and treatment paradigm. | Fei Liu ZixianWang Xiaofan Li Zhen Zhang Yue Yang Junquan Chen Dinghua Chen Lingling Wu Xiangyu Liu Sujun Han Fangming Wang Wasilijiang Wahafu Yibo Gao Shancheng Ren Nianzeng Xing Guangyan Cai Xiangmei Chen | 2023 | Cancer Communications2023，43，2： | 1 |
| 20 | Purification and anticancer activity investigation of pentacyclic triterpenoids from the leaves of Sinojackia sarcocarpa L.Q. Luo by high-speed counter-current chromatography显示文摘 | Sujun Liu Mei Cao Daxu Li Jie Zhang Su Feng Yuanyang Nie Liang Yan Dan Zhang Yan Zhang Zhirong Yang Jian Zhao | 2011 | Natural Product Research2011，，17： | 1 |
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