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4篇 您的检索式:作者名="Steven A. Stacker"
    题名 作者 年代 出处 被引量
1The VEGF signaling pathway in cancer: the road ahead显示文摘The vascular endothelial growth factor (VEGF) family of soluble protein growth factors consists of key mediators of angiogenesis and lymphangiogenesis in the context of tumor biology. The members of the family, VEGF-A (also known as VEGF), VEGF-B, VEGF-C, VEGF-D, and placenta growth factor (PlGF), play important roles in vascular biology in both normal physiology and pathology. The generation of a humanized neutralizing antibody to VEGF-A (bevacizumab, also known as Avastin) and the demonstration of its benefit in numerous human cancers have confirmed the merit of an anti-angiogenesis approach to cancer treatment and have validated the VEGF-A signaling pathway as a therapeutic target. Other members of the VEGF family are now being targeted, and their relevance to human cancer and the development of resistance to anti-VEGF-A treatment are being evaluated in the clinic. Here, we discuss the potential of targeting VEGF family members in the diagnosis and treatment of cancer.Steven A. Stacker Marc G. Achen 2013Chinese Journal of Cancer2013,32,6:13
2Lymphatic endothelium: An important interactive surface for malignant cells显示文摘Rae H. Farnsworth Marc G. Achen Steven A. Stacker 2005Pulmonary Pharmacology & Therapeutics2005,,1:1
3Adenoviral Catheter-Mediated Intramyocardial Gene Transfer Using the Mature Form of Vascular Endothelial Growth Factor-D Induces Transmural Angiogenesis in Porcine Heart显示文摘Juha Rutanen Tuomas T. Rissanen Johanna E. Markkanen Marcin Gruchala P?ivi Silvennoinen Antti Kivel? Antti Hedman Marja Hedman Tommi Heikura Maija-Riitta Ordén Steven A. Stacker Marc G. Achen Juha Hartikainen Seppo Yl?-Herttuala 2004Circulation: Journal of the American Heart Association2004,,8:1
4Signaling for lymphangiogenesis via VEGFR-3 is required for the early events of metastasis显示文摘Masataka Matsumoto Sally Roufail Rachael Inder Carol Caesar Tara Karnezis Ramin Shayan Rae H. Farnsworth Teruhiko Sato Marc G. Achen G. Bruce Mann Steven A. Stacker 2013Clinical & Experimental Metastasis2013,,6:1
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