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| 1 | Determinants of the impact of blood pressure variability on neurological outcome after acute ischaemic stroke显示文摘Introduction: Increased blood pressure variability (BPV) is detrimental after acute ischaemic stroke, but the interaction between BPV and neuroimaging factors that directly influence stroke outcome has not been explored. Methods: We retrospectively reviewed inpatients from 2007 to 2014 with acute anterior circulation ischaemic stroke, CT perfusion and angiography at hospital admission, and a modified Rankin Scale (MRS) 30- 365 days after stroke onset. BPV indices included SD, coefficient of variation and successive variation of the systolic blood pressure between 0 and 120 hours after admission. Ordinal logistic regression models were fitted to MRS with predictor variables of BPV indices. Models were further stratified by CT perfusion volumetric measurements, proximal vessel occlusion and collateral score. Results: 110 patients met the inclusion criteria. The likelihood of a 1-point rise in the MRS increased with every 10 mm Hg increase in BPV (OR for the 3 BPV indices ranged from 2.27 to 5.54), which was more pronounced in patients with larger ischaemic core volumes (OR 8.37 to 18.0) and larger hypoperfused volumes (OR 6.02 to 15.4). This association also held true for patients with larger mismatch volume, proximal vessel occlusion and good collateral vessels. Conclusions: These results indicate that increased BPV is associated with worse neurological outcome after stroke, particularly in patients with a large lesion core volume, concurrent viable ischaemic penumbra, proximal vessel occlusion and good collaterals. This subset of patients, who are often not candidates for or fail acute stroke therapies such as intravenous tissue plasminogen activator or endovascular thrombectomy, may benefit from interventions aimed at reducing BPV. | Adam de Havenon Alicia Bennett Gregory J Stoddard Gordon Smith Lee Chung Steve O’Donnell J Scott McNally David Tirschwell Jennifer J Majersik | 2017 | Stroke & Vascular Neurology2017，2，1： | 6 |
| 2 | Air quality monitoring using mobile microscopy and machine learning显示文摘Rapid,accurate and high-throughput sizing and quantification of particulate matter(PM)in air is crucial for monitoring and improving air quality.In fact,particles in air with a diameter of≤2.5μm have been classified as carcinogenic by the World Health Organization.Here we present a field-portable cost-effective platform for high-throughput quantification of particulate matter using computational lens-free microscopy and machine-learning.This platform,termed c-Air,is also integrated with a smartphone application for device control and display of results.This mobile device rapidly screens 6.5 L of air in 30 s and generates microscopic images of the aerosols in air.It provides statistics of the particle size and density distribution with a sizing accuracy of~93%.We tested this mobile platform by measuring the air quality at different indoor and outdoor environments and measurement times,and compared our results to those of an Environmental Protection Agency–approved device based on beta-attenuation monitoring,which showed strong correlation to c-Air measurements.Furthermore,we used c-Air to map the air quality around Los Angeles International Airport(LAX)over 24 h to confirm that the impact of LAX on increased PM concentration was present even at 47 km away from the airport,especially along the direction of landing flights.With its machinelearning-based computational microscopy interface,c-Air can be adaptively tailored to detect specific particles in air,for example,various types of pollen and mold and provide a cost-effective mobile solution for highly accurate and distributed sensing of air quality. | Yi-Chen Wu Ashutosh Shiledar Yi-Cheng Li Jeffrey Wong Steve Feng Xuan Chen Christine Chen Kevin Jin Saba Janamian Zhe Yang Zachary Scott Ballard Zoltán Göröcs Alborz Feizi Aydogan Ozcan | 2017 | Light(Science & Applications)2017，6，1： | 5 |
| 3 | 安徽铜陵地区幔源镁铁质团块研究及其地质意义显示文摘幔源岩石包体研究,是认识上地幔岩石圈物质组成、幔源岩浆演化及壳幔动力学过程的重要手段。铜陵地区小铜官山石英二长闪长岩中发育有微粒闪长质包体,并且这些微粒闪长质包体中不均匀地分布着镁铁质团块,三者的形成过程可视为铜陵地区岩浆演化的缩影,为了解本区深部岩浆作用过程提供了有力的证据。在前人研究的基础上,笔者借助电子探针、扫描电镜、电镜能谱和二次飞行时间离子探针(Tof-SIMS)对产于铜陵地区微粒闪长质包体中的镁铁质团块进行了详细的研究,首次获得了一套精确的矿物化学资料和元素分布图,总结了镁铁质团块的特征,并讨论了本区的深部岩浆作用过程。矿物学研究表明,镁铁质团块中的角闪石和辉石均已发生了不同程度的透闪石化和阳起石化蚀变,蚀变过程中,从镁钙闪石到镁角闪石,再到透闪石,随着Si的增加,角闪石呈现出Mg的富集和Ti、Al贫化的特点。团块中的富Cr磁铁矿、Ti磁铁矿和少量的铝直闪石指示了其具有深源性。Tof-SIMS元素分布图显示,透闪石主要由Al、Si、Ca、Sc、V、Cr、Mn、Cu和Sr元素组成,透辉石主要由Si、Mg、Ca、Cu和Rb组成。在铜陵地区,上地幔部分熔融形成一套玄武岩浆,受岩浆底侵作用影响,玄武岩浆上侵,进入下地壳深位岩浆房,与下地壳硅镁层发生同化混染作用,形成一套轻度演化的中基性(辉长质)玄武岩浆,镁铁质团块就是这类中基性玄武岩浆直接结晶形成的。后受构造作用影响,这类中基性玄武岩浆上侵到中地壳岩浆房(12-16 km),与中地壳的变质岩系发生同化混染和结晶分异作用形成一套中性闪长质岩浆,微粒闪长质包体就是这套闪长质岩浆发生结晶分异作用而形成的。镁铁质团块和微粒闪长质包体清楚地解释了铜陵地区深部岩浆作用过程,并有力地证明了铜陵地区中地壳的闪长质岩浆来源于下地壳的壳幔混源岩浆。 | 李大鹏 杜杨松 于学峰 秦新龙 Steve SCOTT 王树星 Filipa MARQUES | 2014 | 地球学报2014，35，5： | 4 |
| 4 | Adoption of Laparoscopy for Elective Colorectal Resection: A Report from the Surgical Care and Outcomes Assessment Program显示文摘 | Steve Kwon Richard Billingham Ellen Farrokhi Michael Florence Daniel Herzig Karen Horvath Terry Rogers Scott Steele Rebecca Symons Richard Thirlby Mark Whiteford David R. Flum | 2012 | Journal of the American College of Surgeons2012，，6： | 3 |
| 5 | B lymphocytes regulate airway granulocytic inflammation and cytokine production in a murine model of fungal allergic asthma显示文摘到真菌的促进感受性经常导致是特别地困难的临床上设法的气喘的一种严重形式,导致在这些病人的增加的病态和住院。尽管 B 淋巴细胞可能通过 IgE 的生产加重气喘症状,这些房间可能也在对吸入的真菌的保护的反应是重要的。通过 cytokine 版本和 T 房间相互作用,这些淋巴细胞可能也影响航线墙纤维变性的发展和维护。J H −/− 老鼠为抗体的重链部件缺乏 JH 基因,它为 B 房间功能和幸存是批评的。这些动物在很多有免疫力的回答便于 B 淋巴细胞的角色的说明;然而, J H −/− 老鼠没被用来学习真菌的过敏症。在这研究,我们用曲霉属菌 fumigatus 检验了 B 淋巴细胞的角色模仿被环境真菌的暴露触发的人的航线疾病的鼠科的真菌的高空过敏症模型。我们在敏化的野类型的 BALB/c 和 J 暴露于的 H −/− 老鼠重复了真菌的暴露并且没在大航线附近在航线 hyperresponsiveness,全面肺的发炎或骨胶原免职发现差别。然而, Th2 类型 cytokines IL-4 和 IL-13 的层次显著地在 J 相对 BALB/c 控制的 H −/− 鼠标。由对比,煽动性的 cytokines IL-17A 和 IL-6 的层次显著地在 J H −/− 动物,并且有显著地更柔韧的航线嗜曙红血球过多和 neutrophilia 比在控制动物。一起拿,这些调查结果表明淋巴细胞帮助在肺的分隔空间调整 granulocytic 回答到真菌的暴露的那 B。 | Sumit Ghosh Scott A Hoselton Scott V Asbach Breanne N Steffan Steve B Wanjara Glenn P Dorsam Jane M Schuh | 2015 | Cellular & Molecular Immunology2015，12，2： | 2 |
| 6 | Thermal Management of Vehicle Cabins,External Surfaces,and Onboard Electronics:An Overview显示文摘Reducing heat accumulation within vehicles and ensuring appropriate vehicular temperature levels can lead to enhanced vehicle fuel economy,range,reliability,longevity,passenger comfort,and safety.Advancements in vehicle thermal management remain key as new technologies,consumer demand,societal concerns,and government regulations emerge and evolve.This study summarizes several recent advances in vehicle thermal management technology and modeling,with a focus on three key areas:the cabin,electronics,and exterior components of vehicles.Cabin-related topics covered include methods for reducing thermal loads and improving heating,ventilation,and air-conditioning(HVAC)systems;and advancements in window glazing/tinting and vehicle surface treatments.For the thermal management of electronics,including batteries and insulated-gate bipolar transistors(IGBTs),active and passive cooling methods that employ heat pipes,heat sinks,jet impingement,forced convection,and phase-change materials are discussed.Finally,efforts to model and enhance the heat transfer of exterior vehicular components are reviewed while considering drag/friction forces and environmental effects.Despite advances in the field of vehicle thermal management,challenges still exist;this article provides a broad summary of the major issues,with recommendations for further study. | Garrett J.Marshall Colin P.Mahony Matthew J.Rhodes Steve R.Daniewicz Nicholas Tsolas Scott M.Thompson | 2019 | Engineering2019，5，5： | 2 |
| 7 | 符合性测试和互操作性测试的相关性(第2版)显示文摘传统上讲,符合性测试主要用于电信产业,而互操作性测试主要用于国际互联网络。这两种测试方法存在各自的优点和缺点,结合使用两种方法,能够使测试过程的效果达到最大化;同时还介绍了欧洲电信标准研究院(ETSI)的标准化活动。 | Anthony Wiles Scott Moseley Steve Randall 郭楠 吴东亚 | 2007 | 信息技术与标准化2007，，5： | 2 |
| 8 | Low-temperature deposition of conformal copper films in supercritical CO2 by catalytic hydrogen reduction of copper hexafluoroacetylacetonate显示文摘 | Hiroyuki Ohde Steve Kramer Scott Moore | 2004 | Chemical Materials2004，16，： | 1 |
| 9 | Adefovir-resistant hepatitis B can be associated with viral rebound and hepatic decompensation显示文摘 | Scott K. Fung Pietro Andreone Steve H. Han K. Rajender Reddy Arie Regev Emmet B. Keeffe Munira Hussain Carmela Cursaro Pamela Richtmyer Jorge A. Marrero Anna S.F. Lok | 2005 | Journal of Hepatology2005，，6： | 1 |
| 10 | Breast cancer angiogenesis — new approaches to therapy via antiangiogenesis, hypoxic activated drugs, and vascular targeting显示文摘 | Adrian L. Harris Huatang Zhang Amir Moghaddam Steve Fox Prudence Scott Adam Pattison Kevin Gatter Ian Stratford Roy Bicknell | 1996 | Breast Cancer Research and Treatment1996，，1： | 1 |
| 11 | Phase II Study of Lutetium-177–Labeled Anti-Prostate-Specific Membrane Antigen Monoclonal Antibody J591 for Metastatic Castration-Resistant Prostate Cancer显示文摘 | Scott T. Tagawa Matthew I. Milowsky Michael Morris Shankar Vallabhajosula Paul Christos Naveed H. Akhtar Joseph Osborne Stanley J. Goldsmith Steve Larson Neeta Pandit Taskar Howard I. Scher Neil H. Bander David M. Nanus | 2013 | Clinical Cancer Research2013，，18： | 1 |
| 12 | Apical Hypertrophic Cardiomyopathy: Prevalence and Correlates of Apical Outpouching显示文摘 | Josepha Binder Christine H. Attenhofer Jost Kyle W. Klarich Heidi M. Connolly A. Jamil Tajik Christopher G. Scott Paul R. Julsrud Jo-Ellen Ehrsam Kent R. Bailey Steve R. Ommen | 2011 | Journal of the American Society of Echocardiography2011，，7： | 1 |
| 13 | Three Monte Carlo programs of polarized light transport into scattering media: part Ⅱ显示文摘 | Ramella-Roman Jessica Scott Prahl Jacques Steve | 2005 | Optics Express2005，13，12： | 1 |
| 14 | Rsvp: A new resource reservation protocol 显示文摘 | Lixia Zhang Steve Deering Deborah Estrin Scott Shenker Daniel Zappala | 1993 | IEEE Network Magazine1993，09，： | 1 |
| 15 | A comparison of ethanol and butanol as oxygenates using a direct-injection, spark-ignition engine显示文摘 | Wallner Thomas Miers Scott A McConnell Steve | 2009 | Journal of Engineering for Gas Turbines and Power-Transactions of theASME2009，131，3： | 1 |
| 16 | Breast cancer angiogenesis — new approaches to therapy via antiangiogenesis, hypoxic activated drugs, and vascular targeting显示文摘 | Adrian L. Harris Huatang Zhang Amir Moghaddam Steve Fox Prudence Scott Adam Pattison Kevin Gatter Ian Stratford Roy Bicknell | 1996 | Breast Cancer Research and Treatment1996，，1： | 1 |
| 17 | Adefovir-resistant hepatitis B can be associated with viral rebound and hepatic decompensation显示文摘 | Scott K. Fung Pietro Andreone Steve H. Han K. Rajender Reddy Arie Regev Emmet B. Keeffe Munira Hussain Carmela Cursaro Pamela Richtmyer Jorge A. Marrero Anna S.F. Lok | 2005 | Journal of Hepatology2005，，6： | 1 |
| 18 | Uptake of Metals by Plants Sharing a Rhizosphere with the Hyperaccumulator Thlaspi caerulescens显示文摘 | Benedict Gove Julian J. Hutchinson Scott D. Young Jim Craigon Steve P. McGrath | 2002 | International Journal of Phytoremediation2002，，4： | 1 |
| 19 | Moving into the third, outer domain of teacher satisfaction显示文摘 | Steve Dinham Catherine Scott | 2000 | Journal of Educational Administration2000，，4： | 1 |
| 20 | 铝合金在轨道车辆上的应用显示文摘 | Scott Good Chris Boland Steve Mosser | 2008 | 中国铝业2008，，05： | 1 |
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