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| 1 | 肛裂临床诊治指南(第三次修订)显示文摘“美国结直肠外科医师协会(American Societyof ColonandRectal Surgeons.ASCRS)”(协会)致力于推进结直肠和肛门疾病的相关理论以及预防和诊疗水平的提高,给患者提供优质的医疗服务。“标准委员会”由协会中在结直肠外科方面有显著专长的成员组成。该委员会的建立是为了引领国际结直肠和肛门疾病诊治的发展,以建立具有循证医学证据的临床诊疗指南。指南是涵盖性的,非指令性的,目的是为临床决策提供信息,而非具体的治疗方法。指南适用于所有相关的医护人员以及希望得到相应指南中疾病的相关诊治信息的患者。 | Farshid Araghizadeh ~ Robin Boushey Sridhar Chalasani George Chang Robert Cima Gary Dunn Daniel Feingold Philip Fleshner Daniel Geisler Jill Genua Sharon Gregorcyk Daniel Herzig Andreas Kaiser Ravin Kumar David Larson Steven Mills John Monson P. Terry Phang Feza Remzi David Rivadeneira Howard Ross Peter Senatore Elin Sigurdson Thomas Stahl Scott Steele Scott Strong Charles Tement Judith Trudel Madhulika Varnna Martin Weiser 丁义江(译) 皇甫少华(译) 丁曙晴(译) | 2013 | 中华胃肠外科杂志2013，16，7： | 70 |
| 2 | Magnetic spin–orbit interaction of light显示文摘We study the directional excitation of optical surface waves controlled by the magnetic field of light.We theoretically predict that a spinning magnetic dipole develops a tunable unidirectional coupling of light to transverse electric(TE)polarized Bloch surface waves(BSWs).Experimentally,we show that the helicity of light projected onto a subwavelength groove milled into the top layer of a 1D photonic crystal(PC)controls the power distribution between two TE-polarized BSWs excited on both sides of the groove.Such a phenomenon is shown to be solely mediated by the helicity of the magnetic optical field,thus revealing a magnetic spin-orbit interaction of light.Remarkably,this magnetic optical effect is clearly observed via a near-field coupler governed by an electric dipole moment:it is of the same order of magnitude as the electric optical effects involved in the coupling.This opens up new degrees of freedom for the manipulation of light and offers desirable and novel opportunities for the development of integrated optical functionalities. | Mengjia Wang Hongyi Zhang Tatiana Kovalevich Roland Salut Myun-Sik Kim Miguel Angel Suarez Maria-Pilar Bernal Hans-Peter Herzig Huihui Lu Thierry Grosjean | 2018 | Light(Science & Applications)2018，7，1： | 15 |
| 3 | Defensin expression in chronic pouchitis in patients with ulcerative colitis or familial adenomatous polyposis coli显示文摘瞄准:当在在为家庭腺瘤息肉病关口 i (FAP ) 的 proctocolectomy 以后的病人是稀罕的时, Pouchitis 在小袋外科以后在开始的 10 年期间与 ulcerative 在多达 50% 病人在 ileoanal 小袋发展症候群。Defensins 是天生的免疫系统的主要部件并且在胃肠的微生物引起的动态平衡起一个重要作用。小袋 defensin 和 cytokine 表示与小袋发炎的状态被相关在 pouchitis 学习他们的角色。方法:有 ulcerative 和 FAP 症候群的病人在外科以后与小袋被成层进组,小袋没有或与 pouchitis。从从健康的肠或从有 ulcerative 的病人的正常终端回肠的终端回肠的活体检视用作控制。从小袋和控制的 mRNA 为 defensin 和 cytokine 表示被分析。结果:defensins 的表示在外科以后立即在所有小袋被增加,与控制的回肠相比。开始,在 ulcerative 的小袋比 FAP 小袋揭示了更高的 defensin 表示。Defensin 表示在两个耐心的组衰退了并且与 ulcerative 在病人在 pouchitis 稍微再增加了。没有 pouchitis 的 FAP 小袋有 beta-defensin hBD-1 的强壮的表示,当所有另外的 defensins 在底层留下了时。在 ulcerative 小袋的 Cytokine 表示高,当 FAP 小袋仅仅在外科以后显示出中等提高的 cytokines 时。结论:pouchitis 的开发除了 cytokines 的高表示在 ulcerative 与减少的 defensin 表示相关。在 FAP 小袋的 pouchitis 的低发生与低 cytokine 层次联合与 hBD-1 beta-defensin 的增加的表示相关。 | Karlheinz Kiehne Gabriele Brunke Franziska Wegner Tomas Banasiewicz Ulrich R F lsch Karl-Heinz Herzig | 2006 | World Journal of Gastroenterology2006，12，7： | 8 |
| 4 | 内皮Notch信号的抑制阻碍脂肪酸转运并导致成年心脏的代谢和血管重塑显示文摘营养成分在被肌肉细胞代谢利用之前通过内皮细胞转运。然而,对于内皮运输过程的调节知之甚少。Notch信号传导是发育过程中代谢和血管生成的关键调控因子。在该研究中,Jabs等研究了成年小鼠内皮Notch信号的遗传和药理学调控如何影响内皮脂肪酸转运、心脏血管生成和心脏功能。 | 刘青 叶鹏 Jabs M Rose AJ Lehmann LH Taylor J Moll I Sijmonsma TP Herberich SE Sauer SW Poschet G Federico G Mogler C Weis EM Augustin HG Yan M Gretz N Schmid RM Adams RH Gr9ne HJ Hell R Okun JG Backs J Nawroth PP Herzig S Fischer A | 2018 | 中华高血压杂志2018，26，3： | 6 |
| 5 | Seasonal variations of acute appendicitis and nonspecific abdominal pain in Finland显示文摘AIM:To investigate whether seasonal changes had an effect on the incidence of acute appendicitis(AA)or nonspecific abdominal pain(NSAP).METHODS:We carried out a national register study of all patients with a hospital discharge diagnosis of AA and acute NSAP in Finland.Data were analyzed for the whole country and correlated to seasonal and weather parameters(temperature,humidity).Moreover,additional sub-analyses were performed for five geographically different area of Finland.RESULTS:The observation period spanned 21 years,with 186558 appendectomies,of which 137528(74%)cases were reported as AA.The incidence of AA declined for 32%over the study period.The average incidence of the NSAP was 34/10000 per year.The mean annual temperature,but not relative humidity,showed clear geographical variations.The incidence of AA decreased significantly during the cold months of the year.No correlation was detected between temperature and incidence of NSAP.Humidity had a statistically significant impact on NSAP.CONCLUSION:The incidence of acute appendicitis is declining in Finland.We detected a clear seasonality in the incidence of AA and NSAP. | Imre Ilves Anne Fagerstrm Karl-Heinz Herzig Petri Juvonen Pekka Miettinen Hannu Paajanen | 2014 | World Journal of Gastroenterology2014，20，14： | 6 |
| 6 | 生物毒素的研究与应用:选择性蜘蛛毒揭示Nav1.1通道在机械痛中的作用显示文摘电压门控性钠(Nav)通道参与启动大多数神经元动作电位,其中也包括痛觉初级传入神经纤维。局部麻醉剂可通过非特异性阻断所有Nav通道亚型来抑制疼痛,但探求选择性亚型调节因子将更有助于分析Nav通道亚型对化学、机械或热痛的作用及机制。美国加州大学旧金山分校的Jeremiah D.Osteen,Volker Herzig和David Julius等人通过运用电生理、组织化学及行为学,筛选和鉴定出一种蜘蛛毒素可选择性激活Nav1.1亚基,并阐明其在伤害感受和疼痛中的作用。在非神经炎症的情况下,Nav1.1的激活诱导了疼痛反应,产生了机械性痛觉过敏,而对热痛并无影响。在肠道中,高阈值机械敏感性神经纤维表达Nav1.1,且肠易激综合征模型小鼠也表现为毒素敏感性增强,证实了Nav1.1通道在调节机械痛的感觉神经纤维兴奋性中的作用。 | Jeremiah D.Osteen Volker Herzig John Gilchrist 余书敏 | 2017 | 中国疼痛医学杂志2017，23，2： | 3 |
| 7 | Adoption of Laparoscopy for Elective Colorectal Resection: A Report from the Surgical Care and Outcomes Assessment Program显示文摘 | Steve Kwon Richard Billingham Ellen Farrokhi Michael Florence Daniel Herzig Karen Horvath Terry Rogers Scott Steele Rebecca Symons Richard Thirlby Mark Whiteford David R. Flum | 2012 | Journal of the American College of Surgeons2012，，6： | 3 |
| 8 | Risk factors for carotid plaque progression after optimising the risk factor treatment: substudy results of the Atherosclerotic Plaque Characteristics Associated with a Progression Rate of the Plaque and a Risk of Stroke in Patients with the carotid Bifurcation Plaque Study (ANTIQUE)显示文摘Background and aim Carotid plaque progression contributes to increasing stroke risk.The study aims to identify factors influencing carotid plaque thickness progression after changing the preventive treatment to the‘treating arteries instead of risk factors’strategy,that is,change in treatment depending on the progression of atherosclerosis.Methods The study participants who completed sonographic controls over the course of 3 years were enrolled to the analysis.Duplex sonography of cervical arteries was performed in 6-month intervals with measurement of carotid plaque thickness.Plaque thickness measurement error(σ)was set as 3 SD.Only evidently stable and progressive plaques(defined as plaque thickness difference between initial and final measurements of˂σand>2σ,respectively)were included to analysis.Univariate and multivariate logistic regression analysis was performed to identify factors influencing plaque progression.Results A total of 1391 patients(466 males,age 67.2±9.2 years)were enrolled in the study.Progressive plaque in at least one carotid artery was detected in 255(18.3%)patients.Older age,male sex,greater plaque thickness,coronary heart disease,vascular surgery/stenting history and smoking were more frequently present in patients with progressive plaque(p˂0.05 in all cases).Multivariate logistic regression analysis identified only the plaque thickness(OR 1.850 for left side,95%CI 1.398 to 2.449;and OR 1.376 for right side,95%CI 1.070 to 1.770)as an independent factor influencing plaque progression.Conclusion Carotid plaque thickness corresponding to stenosis severity is the only independent risk factor for plaque thickness progression after optimising the prevention treatment. | David Školoudik Petra Kešnerova Tomaš Hrbač David Netuka Jaroslav Vomačka Kateřina Langova Roman Herzig Tomaš Belšan | 2022 | Stroke & Vascular Neurology2022，7，2： | 3 |
| 9 | Manipulating Bloch surface waves in 2D: a platform concept-based flat lens显示文摘At the end of the 1970s,it was confirmed that dielectric multilayers can sustain Bloch surface waves(BSWs).However,BSWs were not widely studied until more recently.Taking advantage of their high-quality factor,sensing applications have focused on BSWs.Thus far,no work has been performed to manipulate and control the natural surface propagations in terms of defined functions with two-dimensional(2D)components,targeting the realization of a 2D system.In this study,we demonstrate that 2D photonic components can be implemented by coating an in-plane shaped ultrathin(l/15)polymer layer on the dielectric multilayer.The presence of the polymer modifies the local effective refractive index,enabling direct manipulation of the BSW.By locally shaping the geometries of the 2D components,the BSW can be deflected,diffracted,focused and coupled with 2D freedom.Enabling BSW manipulation in 2D,the dielectric multilayer can play a new role as a robust platform for 2D optics,which can pave the way for integration in photonic chips.Multiheterodyne near-field measurements are used to study light propagation through micro-and nano-optical components.We demonstrate that a lens-shaped polymer layer can be considered as a 2D component based on the agreement between near-field measurements and theoretical calculations.Both the focal shift and the resolution of a 2D BSW lens are measured for the first time.The proposed platform enables the design of 2D all-optical integrated systems,which have numerous potential applications,including molecular sensing and photonic circuits. | Libo Yu Elsie Barakat Tristan Sfez Lubos Hvozdara Joab Di Francesco Hans Peter Herzig | 2014 | Light(Science & Applications)2014，3，1： | 3 |
| 10 | Inverse photonic design of functional elements that focus Bloch surface waves显示文摘Bloch surface waves(BSWs)are sustained at the interface of a suitably designed one-dimensional(1D)dielectric photonic crystal and an ambient material.The elements that control the propagation of BSWs are defined by a spatially structured device layer on top of the 1D photonic crystal that locally changes the effective index of the BSW.An example of such an element is a focusing device that squeezes an incident BSW into a tiny space.However,the ability to focus BSWs is limited since the index contrast achievable with the device layer is usually only on the order ofΔn≈0.1 for practical reasons.Conventional elements,e.g.,discs or triangles,which rely on a photonic nanojet to focus BSWs,operate insufficiently at such a low index contrast.To solve this problem,we utilize an inverse photonic design strategy to attain functional elements that focus BSWs efficiently into spatial domains slightly smaller than half the wavelength.Selected examples of such functional elements are fabricated.Their ability to focus BSWs is experimentally verified by measuring the field distributions with a scanning near-field optical microscope.Our focusing elements are promising ingredients for a future generation of integrated photonic devices that rely on BSWs,e.g.,to carry information,or lab-on-chip devices for specific sensing applications. | Yannick Augenstein Andreas Vetter Babak Vosoughi Lahijani Hans Peter Herzig Carsten Rockstuhl Myun-Sik Kim | 2018 | Light(Science & Applications)2018，7，1： | 3 |
| 11 | On the ionicity of carbon in Be2C: A theoretical investigation of its electronic structure显示文摘 | Herzig P Redinger J | 1985 | J Chem Phys1985，82，： | 1 |
| 12 | Emulsifi cation of Partially Miscible Liquids Using Colloidal Parti cles: Nonspherical and Extended Domain Structures显示文摘 | Clegg P S Herzig E M Sehofield A B | 2007 | Langmuir2007，23，： | 1 |
| 13 | Hydrothermal silica chimney field in the Galapagos Spreading Center at 86°W 显示文摘 | Herzig P M Beckor K P Stoffers P | 1988 | Earth and Planetary Science Letters1988，89，： | 1 |
| 14 | Atopic eczema in early childhood could be protective against Type 1 diabetes显示文摘 | Dr. J. Rosenbauer P. Herzig G. Giani | 2003 | Diabetologia2003，，6： | 1 |
| 15 | Acid-suppressive medication use in acute stroke and hospital-acquired pneumonia显示文摘 | Herzig S J Doughty C Lahoti S | 2014 | Ann Neurol2014，76，5： | 1 |
| 16 | A prospective crossover trial comparing intermittent intravenous and continuous oral iron supplements in peritoneal dialysis patients显示文摘 | Johnson DW Herzig KA Gissane R | 2001 | Nephrol Dial Transplant2001，16，9： | 1 |
| 17 | Long-term follow up of factual knowledge after a single,randomised problem-based learning course显示文摘 | HERZIG S LINKE R M MARXEN B | 2003 | BMC Medical Education2003，，3： | 1 |
| 18 | Beam shaping for high power laser diode array by holographic optical elements in holographic systems显示文摘 | Herzig H P D(a)ndliker R Teijido J M | 1989 | Components and Applications1989，311，： | 1 |
| 19 | Mitochondrial dynamics and cancer显示文摘 | Grandemange S Herzig S Martinou J C | 2009 | Semin Cancer Biol2009，19，： | 1 |
| 20 | Signaling cross - talk between hypoxia and glucose via hypoxia - inducible factor 1 and glucose response elements显示文摘 | Kietzmarm T Krones - Herzig A Jtmgermann K | 2002 | Biochemical pharmacology2002，64，： | 1 |
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