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| 1 | Real-life chromoendoscopy for dysplasia surveillance in ulcerative colitis显示文摘AIM To evaluate the use of chromoendoscopy for surveillance of ulcerative colitis in a real-life community hospital setting.METHODS Patients with extensive ulcerative colitis, having disease duration of more than 8 years and who presented between the years of 1999 to 2013, were offered enrolment in this single cohort prospective study. All participants underwent standard bowel preparation with sodium phosphate and chromoendoscopy. Two expert endoscopists, novice to chromoendoscopy, evaluated each segment of the colon with standarddefinition colonoscopes after spray application of 0.4% indigo carmine. All observed lesions were recorded and evaluated before being removed and/or biopsied. In addition, nontargeted biopsies were taken from each segment of the colon. The dysplasia detection rate and dysplasia detection yield were ascertained. RESULTS A total of 21 neoplastic lesions(2 carcinomas, 4 of high-grade dysplasia and 15 of low-grade dysplasia) and 27 nondysplastic lesions were detected in 16 of the total 67 patients(70% male; median disease duration: 17 years; median age at diagnosis: 25 years; 92% aminosalicylate-treated). The dysplasia detection rate was 10.5%(7/67 patients). The dysplasia detection yield was 20.8%(10/48) for targeted biopsies and 3.5%(11/318) for nontargeted biopsies. The sensitivity and specificity for the macroscopic evaluation of neoplasia using chromoendoscopy were 48% [95% confidence interval(CI): 26%-70%] and 96%(95%CI: 93%-98%), respectively. The positive predictive and negative predictive values were 42%(95%CI: 27%-59%) and 97%(95%CI: 95%-98%), respectively. A total of 19/21 dysplastic lesions were detected in mucosa with histologic inflammation.CONCLUSION Chromoendoscopy seems to be of value for dysplasia surveillance of ulcerative colitis in a community hospital setting. The yield of non-targeted biopsies is negligible. | Pasquale Klepp Anita Tollisen Arne Roseth Milada Cvancarova Smastuen Solveig N Andersen Morten Vatn Bjorn A Moum Stephan Brackmann | 2018 | World Journal of Gastroenterology2018，24，35： | 3 |
| 2 | Long-Term Follow-Up of Biopsy-Proven Viral Myocarditis显示文摘 | Stefan Grün Julia Schumm Simon Greulich Anja Wagner Steffen Schneider Oliver Bruder Eva-Maria Kispert Stephan Hill Peter Ong Karin Klingel Reinhardt Kandolf Udo Sechtem Heiko Mahrholdt | 2012 | Journal of the American College of Cardiology2012，，18： | 2 |
| 3 | Selective interaction of a semiconjugated organic polymer with single-wall nanotubes 显示文摘 | Dalton A Stephan C Coleman J N | 2000 | J Phys Chem B2000，104，10： | 1 |
| 4 | Absolute atomic oxygen density profiles in the discharge core of a microscale atmospheric pressure plasma jet显示文摘 | Nikolas K Karl N Stephan R | 2008 | Applied Physics Letters2008，93，13： | 1 |
| 5 | Residual bodies activate Sertoli cell interleukin 1 alpha (IL-1 alpha) release, which triggers IL-6 production by an autoerine mechanism, through the lipoxygenase pathway显示文摘 | Syed V Stephan JP Gerard N | 1995 | Endocrinology1995，136，7： | 1 |
| 6 | The effect of regulatory focus on the shape of probability-weighting function: Evidence from a cross modality matching method显示文摘 | Kluger A N Stephan E Ganzach Y and Hershkovitz M | 2004 | Organizational Behavior and Human Decision Processes2004，95，1： | 1 |
| 7 | Light interception and partitioningbetween shoots in apple cultivars influenced by training显示文摘 | Stephan J Sinoquet H Dones N | 2008 | Tree Physiology2008，28，： | 1 |
| 8 | PET and MRI in cardiac imaging: from vali?dation studies to integrated applications显示文摘 | Stephan G N ekolla Axel Martinez - Moeller Antti Saraste | 2009 | EurJ Nucl Med Mol Imaging2009，36，1： | 1 |
| 9 | Apoptosis ofendothelial cells precedes myocyte cell apoptosis in ischemia/reperfusion injury显示文摘 | Scarabelli T Stephanou A Rayment N | 2001 | Circulation2001，104，3： | 1 |
| 10 | CarD is an essential regulator of rRNA transcription required for Mycobacterium tuberculosis persistence显示文摘 | Stallings C L Stephanou N C Chu L | 2009 | Cell2009，138，1： | 1 |
| 11 | Numerical modeling of general cracks from the viewpoint of eddy current simulations显示文摘 | Yusa N Stephane Perrin Kazue Mizuno | 2007 | NDT&E2007，，4： | 1 |
| 12 | Epidemiological and molecular trends of norwalk - like viruses associated with outbreaks of gastroenteritis in the United States 显示文摘 | REBECCA L F STEPHAN S M JACQUELINE S N | 2002 | J Infec Dis2002，186，： | 1 |
| 13 | Apoptosis of endothelial cells precede myocyte cell apoptosis in ischemia/reperfusion injury 显示文摘 | SCARABELLI T STEPHANOU A RAYMENT N | 2001 | Circulation2001，104，： | 1 |
| 14 | In vitro alterations of intestinal bacterial microbiota in fecal samples during storage显示文摘 | Stephan J O Meike M Kenneth N T | 2004 | Diagnostic Microbiology and Infectious Disease2004，50，： | 1 |
| 15 | Filling carbon nanotubes with metals by the arc - discharge method: the key role of sulfur显示文摘 | Demoncy N Stephan O Brun N | 1998 | The European Physical Journal B - Condensed Matter and Complex Systems1998，4，2： | 1 |
| 16 | Apoptosis of endothelial cells precedes myocyte cell apoptosis in ischemia/reperfusion injury 显示文摘 | Scarbelli T Stephanou A Rayment N | 2001 | Circulation2001，104，3： | 1 |
| 17 | Influence of combined doping of tricalcium silicate with MgO, Al2O3 and Fe2O3: synthesis, grindability, X-ray diffraction and 29Si NMR 显示文摘 | STEPHAN D DIKOUNDOU S N RAUDASHL-SIEBER G | 2008 | Mater Struct2008，41，： | 1 |
| 18 | Apoptosis of endothelial cells precedes myocyte cell apoptosis in ischemia/reperfusion injury显示文摘 | Stephanou A Rayment N | 2001 | Circulation2001，104，3： | 1 |
| 19 | Iso-and anteiso-alkanes: specific tracers of environmental tobacco smoke in indoor and outdoor particle-size distributed urban aerosols显示文摘 | Kavouras I G Stratigakis N Stephanou E G | 1998 | Enviromnental Science and Technology1998，32，10： | 1 |
| 20 | Hydration characteristics and hydration products of tricalcium silicate doped with a combination of MgO, Al2O3 and Fe2O3 显示文摘 | STEPHAN D DIKOUNDOU S N RAUDASHL-SIEBER G | 2008 | Thermochimi Acta2008，472，： | 1 |
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