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您的检索式：作者名="Stephan Brackmann"
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| 1 | Real-life chromoendoscopy for dysplasia surveillance in ulcerative colitis显示文摘AIM To evaluate the use of chromoendoscopy for surveillance of ulcerative colitis in a real-life community hospital setting.METHODS Patients with extensive ulcerative colitis, having disease duration of more than 8 years and who presented between the years of 1999 to 2013, were offered enrolment in this single cohort prospective study. All participants underwent standard bowel preparation with sodium phosphate and chromoendoscopy. Two expert endoscopists, novice to chromoendoscopy, evaluated each segment of the colon with standarddefinition colonoscopes after spray application of 0.4% indigo carmine. All observed lesions were recorded and evaluated before being removed and/or biopsied. In addition, nontargeted biopsies were taken from each segment of the colon. The dysplasia detection rate and dysplasia detection yield were ascertained. RESULTS A total of 21 neoplastic lesions(2 carcinomas, 4 of high-grade dysplasia and 15 of low-grade dysplasia) and 27 nondysplastic lesions were detected in 16 of the total 67 patients(70% male; median disease duration: 17 years; median age at diagnosis: 25 years; 92% aminosalicylate-treated). The dysplasia detection rate was 10.5%(7/67 patients). The dysplasia detection yield was 20.8%(10/48) for targeted biopsies and 3.5%(11/318) for nontargeted biopsies. The sensitivity and specificity for the macroscopic evaluation of neoplasia using chromoendoscopy were 48% [95% confidence interval(CI): 26%-70%] and 96%(95%CI: 93%-98%), respectively. The positive predictive and negative predictive values were 42%(95%CI: 27%-59%) and 97%(95%CI: 95%-98%), respectively. A total of 19/21 dysplastic lesions were detected in mucosa with histologic inflammation.CONCLUSION Chromoendoscopy seems to be of value for dysplasia surveillance of ulcerative colitis in a community hospital setting. The yield of non-targeted biopsies is negligible. | Pasquale Klepp Anita Tollisen Arne Roseth Milada Cvancarova Smastuen Solveig N Andersen Morten Vatn Bjorn A Moum Stephan Brackmann | 2018 | World Journal of Gastroenterology2018，24，35： | 3 |
| 2 | Relationship between clinical parameters and the colitis-colorectal cancer interval in a cohort of patients with colorectal cancer in inflammatory bowel disease显示文摘 | Stephan Brackmann Solveig N. Andersen Geir Aamodt Fr?ydis Langmark Ole P. F. Clausen Erling Aadland Olav Fausa Andreas Rydning Morten H. Vatn | 2009 | Scandinavian Journal of Gastroenterology2009，，1： | 1 |
| 3 | Age-Dependent Fecal Bacterial Correlation to Inflammatory Bowel Disease for Newly Diagnosed Untreated Children显示文摘 | Felix Chinweije Nwosu Lill-Therse Thorkildsen Ekaterina Avershina Petr Ricanek G?ri Perminow Stephan Brackmann Morten H. Vatn Knut Rudi Devendra Amre | 2013 | Gastroenterology Research and Practice2013，，： | 1 |
| 4 | Evaluation of disease activity in IBD at the time of diagnosis by the use of clinical, biochemical, and fecal markers显示文摘 | Petr Ricanek Stephan Brackmann G?ri Perminow Lars G. Lyckander Jon Sponheim ?yvind Holme Ole H?ie Andreas Rydning Morten H. Vatn | 2011 | Scandinavian Journal of Gastroenterology2011，，9： | 1 |
| 5 | Evaluation of disease activity in IBD at the time of diagnosis by the use of clinical, biochemical, and fecal markers显示文摘 | Petr Ricanek Stephan Brackmann G?ri Perminow Lars G. Lyckander Jon Sponheim ?yvind Holme Ole H?ie Andreas Rydning Morten H. Vatn | 2011 | Scandinavian Journal of Gastroenterology2011，，9： | 1 |
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