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| 1 | Impact of anthropogenic drivers on subaqueous topographical change in the Datong to Xuliujing reach of the Yangtze River显示文摘Changes of subaqueous topography in shallow offshore water pose safety risks for embankments,navigation,and ports.This study conducted measurements of subaqueous topography between Datong and Xuliujing in the Yangtze River using a Sea Bat 7125 multi-beam echo sounder,and the channel change from 1998 to 2013 was calculated using historical bathymetry data.The study revealed several important results:(1)the overall pattern of changes through the studied stretch of the river was erosion–deposition–erosion.Erosion with a volume 700×10~6m^3occurred in the upper reach,deposition of about 204×10~6m^3occurred in the middle reach,and erosion of about 602×10~6m^3occurred in the lower reach.(2)Dunes are the most common microtopographic feature,accounting for 64.3%of the Datong to Xuliujing reach,followed by erosional topography and flat river topography,accounting for 27.6%and 6.6%,respectively.(3)Human activities have a direct impact on the development of the microtopography.For instance,the mining of sand formed holes on the surface of dunes with lengths of 20–35 m and depths of 3–5 m.We concluded that the overall trend of erosion(net erosion volume of 468×10~6m^3)occurred in the study area mainly because of the decreased sediment discharge following the closure of the Three Gorges Dam.However,other human activities were also impact factors of topographic change.Use of embankments and channel management reduced channel width,restricted river meandering,and exacerbated the erosion phenomenon. | Shuwei ZHENG Heqin CHENG Shengyu SHI Wei XU Quanping ZHOU Yuehua JIANG Fengnian ZHOU Minxiong CAO | 2018 | Science China Earth Sciences2018，61，7： | 10 |
| 2 | Tea plant genomics:achievements,challenges and perspectives显示文摘Tea is among the world’s most widely consumed non-alcoholic beverages and possesses enormous economic,health,and cultural values.It is produced from the cured leaves of tea plants,which are important evergreen crops globally cultivated in over 50 countries.Along with recent innovations and advances in biotechnologies,great progress in tea plant genomics and genetics has been achieved,which has facilitated our understanding of the molecular mechanisms of tea quality and the evolution of the tea plant genome.In this review,we briefly summarize the achievements of the past two decades,which primarily include diverse genome and transcriptome sequencing projects,gene discovery and regulation studies,investigation of the epigenetics and noncoding RNAs,origin and domestication,phylogenetics and germplasm utilization of tea plant as well as newly developed tools/platforms.We also present perspectives and possible challenges for future functional genomic studies that will contribute to the acceleration of breeding programs in tea plants. | En-Hua Xia Wei Tong QiongWu ShuWei Jian Zhao Zheng-Zhu Zhang Chao-Ling Wei Xiao-Chun Wan | 2020 | Horticulture Research2020，7，1： | 9 |
| 3 | Sand mining impact on Poyang Lake: a case study based on high-resolution bathymetry and sub-bottom data显示文摘Poyang Lake in the Changjiang(Yangtze)River catchment has undergone frequent spring drought since 2003,and some researchers attributed this phenomenon to sand mining and the lakebed deformation in the outlet channel linking the lake with Changjiang River main channel.However,there is still a lack of high-resolution subaqueous geomorphological evidence of how sand mining led to lakebed deformation in the outlet channel.We examined the bed morphology and sub-bottom sedimentary structure of the outlet channel,using a multibeam echo sounder and sub-bottom profi ler in Poyang Lake.We found that:(1)the subaqueous micro-topography types of the outlet channel are characterized by sand mining disturbance,natural erosional topography,and fl at bed and dunes,accounting for 44.9%,21.4%,28.6%,and 5.1%of the channel area,respectively;and(2)sand mining activity aff ects the local bed topography extensively and signifi cantly.The depth of sandpits caused by sand mining varied from 1.4 m to 12 m deeper than the surrounding bed surface,with 4.41 m of depth increase on average.Hence,the large-scale high-intensity sand mining activities and their signifi cant geomorphic eff ects demand for an improved assessment for future management and longer-term sustainability.Because of the large-scale and ongoing high-intensity sand mining activities in the Poyang Lake outlet channel,these eff ects should raise caution in the future and contribute to monitoring eff orts that are essential to implement sustainable management solutions.The present study and techniques implemented can serve as a scientifi c reference for dam construction and sand mining within the Poyang Lake basin. | Shuwei ZHENG Heqin CHENG Ming TANG Wei XU Enfeng LIU Shu GAO Jim BEST Yuehua JIANG Quanping ZHOU | 2022 | Journal of Oceanology and Limnology2022，40，4： | 3 |
| 4 | Enhanced aerobic granulation and nitrogen removal by the addition of zeolite powder in a sequencing batch reactor显示文摘 | Dong Wei Xiaodong Xue Shuwei Chen | 2013 | Applied Microbiology and Biotechnology2013，97，20： | 1 |
| 5 | The Effect of Different Potassium Fertilizers on Fruit Flavor Quality of ‘Xinliqihao’ Pear显示文摘[Objectives] This study was conducted to investigate the effects of different types of potassium fertilizers on the flavor and quality of pear fruit.[Methods] With ‘Xinliqihao’ as a research object,such three treatments as potassium sulfate (T1),potassium nitrate (T2) and potassium chloride (T3) were set up,with no application of potassium fertilizer as control (CK).All the fertilizers were applied into soil in the growing season.[Results] The total sugar content of ‘Xinliqihao’ was significantly higher in the potassium fertilizer treatments than that of the control.The total sugar content of T 2 (the potassium sulfate treatment) was the highest,which was 34.55% higher than that of the control,sequentially followed by T3 (the potassium nitrate treatment) and T1 (the potassium chloride treatment).The contents of fructose,glucose and sucrose in the potassium sulfate treatment were all the highest,which were 15.96%,27.32% and 52.81% higher than those of the potassium chloride treatment,respectively,and 11.36%,27.75% and 20.45% higher than the potassium nitrate treatment,respectively.The total acid content of ‘Xinliqihao’ fruit treated with different types of potassium fertilizers was higher than that of the control.The total acid content of the potassium nitrate treatment was the highest,which was 103.68% higher than that of the control,sequentially followed by the potassium sulfate treatment and the potassium chloride treatment.Both the control and potassium treatments of ‘Xinliqihao’ had the highest malic acid content,and except the potassium chloride treatment with the lowest fumaric acid content,other treatments all had the lowest tartaric acid content.Different types of potassium fertilizer treatments had different effects on the organic acid content of ‘Xinliqihao’ fruit.The types and contents of volatile aroma substances in the fruit of ‘Xinliqihao’ treated with potassium fertilizers were significantly higher than the control.The aroma substances in ‘Xinliqihao’ differed among different potassium fertilizer treatments.Specifically,78 kinds of aroma substances were detected in the potassium chloride treatment,and the total content of aroma components was the highest at 746.609 ng/g in the fruit of the potassium sulfate treatment.[Conclusions] The potassium fertilizer treatments improved the flavor and quality of ‘Xinliqihao’ pear fruit,and the potassium sulfate treatment exhibited the best effects. | Shuwei WEI Shaomin WANG Xiaochang DONG Yong ZHANG Ran DONG Kun RAN Hongwei WANG | 2019 | Agricultural Biotechnology2019，8，5： | 1 |
| 6 | Optimisation Method for Determination of Crack Tip Position Based on Gauss-Newton Iterative Technique显示文摘In the digital image correlation research of fatigue crack growth rate,the accuracy of the crack tip position determines the accuracy of the calculation of the stress intensity factor,thereby affecting the life prediction.This paper proposes a Gauss-Newton iteration method for solving the crack tip position.The conventional linear fitting method provides an iterative initial solution for this method,and the preconditioned conjugate gradient method is used to solve the ill-conditioned matrix.A noise-added artificial displacement field is used to verify the feasibility of the method,which shows that all parameters can be solved with satisfactory results.The actual stress intensity factor solution case shows that the stress intensity factor value obtained by the method in this paper is very close to the finite element result,and the relative error between the two is only−0.621%;The Williams coefficient obtained by this method can also better define the contour of the plastic zone at the crack tip,and the maximum relative error with the test plastic zone area is−11.29%.The relative error between the contour of the plastic zone defined by the conventional method and the area of the experimental plastic zone reached a maximum of 26.05%.The crack tip coordinates,stress intensity factors,and plastic zone contour changes in the loading and unloading phases are explored.The results show that the crack tip change during the loading process is faster than the change during the unloading process;the stress intensity factor during the unloading process under the same load condition is larger than that during the loading process;under the same load,the theoretical plastic zone during the unloading process is higher than that during the loading process. | Bing Yang Zhanjiang Wei Zhen Liao Shuwei Zhou Shoune Xiao Tao Zhu Guangwu Yang Mingmeng Wang | 2021 | Chinese Journal of Mechanical Engineering2021，34，4： | 1 |
| 7 | Ca^(2+)-dependent TaCCD1 cooperates with TaSAUR215 to enhance plasma membrane H^(+)-ATPase activity and alkali stress tolerance by inhibiting PP2C-mediated dephosphorylation of TaHA2 in wheat显示文摘Alkali stress is a major constraint for crop production in many regions of saline-alkali land.However,little is known about the mechanisms through which wheat responds to alkali stress.In this study,we identified a calcium ion-binding protein from wheat,TaCCD1,which is critical for regulating the plasma membrane(PM)H^(+)-ATPase-mediated alkali stress response.PM H+-ATPase activity is closely related to alkali tolerance in the wheat variety Shanrong 4(SR4).We found that two D-clade type 2C protein phosphatases,TaPP2C.D1 and TaPP2C.D8(TaPP2C.D1/8),negatively modulate alkali stress tolerance by dephosphorylating the penultimate threonine residue(Thr926)of TaHA2 and thereby inhibiting PM H+-ATPase activity.Alkali stress induces the expression of TaCCD1 in SR4,and TaCCD1 interacts with TaSAUR215,an early auxin-responsive protein.These responses are both dependent on calcium signaling triggered by alkali stress.TaCCD1 enhances the inhibitory effect of TaSAUR215 on TaPP2C.D1/8 activity,thereby promoting the activity of the PM H^(+)-ATPase TaHA2 and alkali stress tolerance in wheat.Functional and genetic analyses verified the effects of these genes in response to alkali stress,indicating that TaPP2C.D1/8 function downstream of TaSAUR215 and TaCCD1.Collectively,this study uncovers a new signaling pathway that regulates wheat responses to alkali stress,in which Ca^(2+)-dependent TaCCD1 cooperates with TaSAUR215 to enhance PM H+-ATPase activity and alkali stress tolerance by inhibiting TaPP2C.D1/8-mediated dephosphorylation of PM H+-ATPase TaHA2 in wheat. | Minghan Cui Yanping Li Jianhang Li Fengxiang Yin Xiangyu Chen Lumin Qin Lin Wei Guangmin Xia Shuwei Liu | 2023 | Molecular Plant2023，16，3： | 1 |
| 8 | Mesenchymal stromal cells alleviate acute respiratory distress syndrome through the cholinergic anti-inflammatory pathway显示文摘Mesenchymal stromal cells(MSCs)have been considered a promising alternative for treatment of acute respiratory distress syndrome(ARDS).However,there is significant heterogeneity in their therapeutic efficacy,largely owing to the incomplete understanding of the mechanisms underlying the therapeutic activities of MSCs.Here,we hypothesize that the cholinergic antiinflammatory pathway(CAP),which is recognized as a neuroimmunological pathway,may be involved in the therapeutic mechanisms by which MSCs mitigate ARDS.Using lipopolysaccharide(LPS)and bacterial lung inflammation models,we found that inflammatory cell infiltration and Evans blue leakage were reduced and that the expression levels of choline acetyltransferase(ChAT)and vesicular acetylcholine transporter(VAChT)in lung tissue were significantly increased 6 hours after MSC infusion.When the vagus nerve was blocked orα7 nicotinic acetylcholine(ACh)receptor(α7nAChR)-knockout mice were used,the therapeutic effects of MSCs were significantly reduced,suggesting that the CAP may play an important role in the effects of MSCs in ARDS treatment.Our results further showed that MSC-derived prostaglandin E2(PGE2)likely promoted ACh synthesis and release.Additionally,based on the efficacy of nAChR andα7nAChR agonists,we found that lobeline,the nicotinic cholinergic receptor excitation stimulant,may attenuate pulmonary inflammation and alleviate respiratory symptoms of ARDS patients in a clinical study(ChiCTR2100047403).In summary,we reveal a previously unrecognized MSC-mediated mechanism of CAP activation as the means by which MSCs alleviate ARDS-like syndrome,providing insight into the clinical translation of MSCs or CAP-related strategies for the treatment of patients with ARDS. | Xiaoran Zhang Xuxia Wei Yiwen Deng Xiaofeng Yuan Jiahao Shi Weijun Huang Jing Huang Xiaoyong Chen Shuwei Zheng Jieying Chen Keyu Chen Ruiming Xu Hongmiao Wang Weiqiang Li Shiyue Li Huimin Yi Andy Peng Xiang | 2022 | Signal Transduction and Targeted Therapy2022，7，10： | 1 |
| 9 | The role of low air pressure in the variation of negative corona-generated space charge in a rod to plane electrode显示文摘The corona-generated space charge may vary in different air pressures,and the quantitative law between the corona-generated space charge density and air pressure has never been investigated.This work utilised computational approaches to explore the role of air pressure in the variation of negative corona-generated space charge.A negative fluid model in which the air pressure could be varied was built up to calculate the charged-particle density and electric field under different applied voltages.The continuity equations were solved by flux corrected transport algorithm and the Poisson equation was computed by the successive over relaxation method.The variations of important parameters due to air pressure were analysed.The particles densities of electrons,positive ions and negative ions at standard and low atmosphere pressures were computed,which increased markedly due to the decrease of atmosphere pressure.At fixed applied voltages,the exponential decay law between the maximal values of electron/positive ion densities at the head of the streamer and air pressure could be obtained.The quantitative law between the maximal values of electron/positive ion densities at the head of the streamer and the applied voltage,relative air density was also achieved. | Bian XingMing Zhu JunYu Yang Wei Wan ShuWei Qi Lei Li XueBao Li HaiBing | 2018 | High Voltage2018，3，2： | 1 |
| 10 | Chemoenzymatic synthesis amphiphilic H-shaped copolymer and its self-assembly behavior显示文摘ABA triblock copolymers were synthesized by dihydroxyl-capped PEO initiated enzymatic ring-opening polymerization (eROP) of ε-CL in the presence of biocatalyst Novozyme 435. The chains ended with hydroxyl of block copolymers were modified by the esterification of 2,2-dichloro acetyl chloride (DCAC) to obtain the tetrafunctional macroinitiator,which was used in the ATRP of 4-vinylpyridine (4-VP). CuCl/HMTETA was used as the catalyst system in the ATRP of 4-VP to acquire the H-shaped block copolymers (PVP)2-b-PCL-b-PEG-b-PCL-b-(PVP)2. The H-shaped block copolymers were characterized by FTIR,NMR,and GPC. Copolymers with high molecular weights (Mn = 46121 g/mol) and low polydispersities (Mw/Mn = 1.30) were prepared. Moreover,the morphology of the copolymer was examined with dynamic light scattering (DLS) and atomic force microscopy (AFM). Spherical micelles with a diameter of 70 nm in aqueous solution were obtained. | ShuWei Wang Bao Zhang Peng Ai Ming Zhu Wei Wang ZhongPeng Sa LiNa Ma YaPeng Li | 2009 | Science China Chemistry2009，52，12： | 1 |
| 11 | High Performance Liquid Chromatography Analysis of Sugars and Acid Components in ’Xintai Tianhong’ Hawthorn Fruit显示文摘[Objectives]This study was conducted to provide basic information for the utilization,quality control and deep processing of‘Xintai Tianhong’hawthorn fruit resources.[Methods]The contents of sugar and acid components in‘Xintai Tianhong’hawthorn fruit were determined by high performance liquid chromatography(HPLC).[Results]‘Xintai Tianhong’hawthorn fruit contained such four kinds of sugar components as fructose,sorbitol,glucose and sucrose,and such six kinds of organic acid components as oxalic acid,tartaric acid,malic acid,acetic acid,citric acid and succinic acid.The fruit had the highest sucrose content,accounting for 70.53%of the total sugar content,followed by fructose,glucose and sorbitol.For the organic acid components,the content of succinic acid was the highest,accounting for 47.32%of the total acid content,followed by citric acid,malic acid,oxalic acid and tartaric acid,and acetic acid had the lowest content.[Conclusions]‘Xintai Tianhong’hawthorn should be a succinic acid-type hawthorn variety,which can be used as a parent in genetic research and breeding practice. | Shuwei WEI Shaomin WANG | 2019 | Agricultural Biotechnology2019，8，4： | 1 |
| 12 | A method to determine the bonded-particle model parameters for simulation of ores显示文摘The bonded-particle model(BPM)is commonly used in the numerical analysis of ore samples.To improve the accuracy of simulating the mechanical process of ore process of ore crushing in a crusher,the parameters of the BPM for the ore must be calibrated.In this study,a calibration method was proposed for the scientific determination of the parameters of the BPM for ore undergoing uniaxial compression.First,physical tests and simulations were conducted to determine the mechanical response(uniaxial compressive strength and macroscopic stiffness)of ore during uniaxial compression.Then,the sensitivity of the mechanical response to the values of microscopic parameters was tested using a Plackett-Burman design.Next,the microscopic parameters with the greatest impact on the response were identified,and the range of parameters that met the target response was determined using a steepest ascent design;Second,a second-order model of the mechanical response was established using the sensitive parameters by combining a Box-Behnken design with response surface methodology to obtain the optimal BPM parameters.Simulation tests showed that the normal stiffness per unit area,critical shear stress,and bonded disk radius had significant effects on the uniaxial compressive strength(UCS)and macroscopic stiffness(MS).To verify the validity of the proposed calibration method,laboratory tests were conducted.The consistency of the simulation results with experimental results indicated that response surface methodology with the Plackett-Burman design,steepest ascent design,and Box-Behnken design can be an effective method for calibrating the BPM of ores. | Shuwei Wu Guoqiang Wang Longfei Fan Wei Guan Jianbo Guo Zhengbin Liu Yukuan Wang | 2024 | Particuology2024，86，3： | 0 |
| 13 | Controllable speckle compression in atomic vapor by frequency modulation and its application in ghost imaging显示文摘An image undergoes a paraxial diffraction spreading when propagating in free space.The reduction of diffraction is critical for many potential applications[1-3].Recently,it has been recognized that optical diffraction can be greatly suppressed or even eliminated by using atomic coherence effects[4-9].Several experimental attempts to extent the | JinWen Wang Xin Yang ShuWei Qiu Ming Tao Cao Dong Wei Hong Gao FuLi Li | 2018 | Science China(Physics,Mechanics & Astronomy)2018，61，9： | 0 |
| 14 | Industrial Economy Analysis of Main Pear-producing Counties in Central and Western Shandong Province(2011-2020)显示文摘This paper selected five main producing counties of Yangxin,Guanxian,Feixian,Tengzhou and Licheng in central and western Shandong Province.Based on the basic economic data of pear industry from 2011 to 2020,the cultivation areas,yields,main cultivars,production costs and garden prices of pears in the main producing counties in the past 10 years were analyzed,so as to provide reference for the development of pear industry in Shandong Province. | Shuwei WEI Xiaoyang WANG | 2022 | Agricultural Biotechnology2022，11，3： | 0 |
| 15 | Investigation of Tree Structure Parameters of High-quality and High-yielding Y-shaped Pear Orchards显示文摘In order to study reasonable tree structure parameters of Y-shaped pear orchards in natural conditions and at management technical level of Tai'an area, the tree structure and population structure of high-quality and high-yielding Y-shaped pear orchards were investigated. The results showed that when the yield of Y-shaped 'Oshu' was 2 550 kg/667 m^2 in the early fully fruiting period, the quantity of the branches per 667 m^2 was about 54 000, and the number of short branches was the largest, accounting for 80.1% of total number of branches, followed by middle branches, long branches and developmental branches. As the yield of Y-shaped 'Qiuyue' was 2 875 kg/667 m^2 in the early fully fruiting period, the quantity of the branches per 667 m^2 was 51 000, and the number of short branches was the largest, accounting for 75.6% of total number of branches, followed by middle branches, long branches and developmental branches. When the yield of Y-shaped 'Niitaka' was 3 000 kg/667 m^2 in the early fully fruiting period, the quantity of the branches per 667 m^2 was 43 000, and the number of short branches was the largest, accounting for 82.0% of total number of branches, followed by long branches, middle branches and developmental branches. | Shuwei WEI Shaomin WANG Ran DONG Kun RAN Hongwei WANG | 2019 | Agricultural Biotechnology2019，8，2： | 0 |
| 16 | Present Situation, Existing Problems and Recommendations for Orchard Fertilization Technology显示文摘This paper summarizes the development process and research status of orchard fertilization technology,introduces many kinds of fertilization methods,such as soil testing and fertilizer recommendation method,and nutrition diagnosis method,probes into the main problems existing in orchard fertilization,and puts forward some suggestions for solving them. The development of orchard fertilization technology in China is also projected. | Shuwei WEI Shaomin WANG Yao TONG Xiaochang DONG Ran DONG Hongwei WANG Kun RAN Yong ZHANG | 2019 | Asian Agricultural Research2019，11，12： | 0 |
| 17 | Development of solid base catalyst X/Y/MgO/-Al_(2)O_(3) for optimization of preparation of biodiesel from Jatropha curcas L.seed oil显示文摘The preparation and regeneration conditions of the identified catalyst X/Y/MgO/?-Al2O3 with high catalytic activity were studied and optimized. The biodiesel was prepared by transesterification of Jatropha curcas seed oil produced in Guizhou with methanol at its reflux temoerature in the presence of X/Y/MgO/?-Al2O3 . The pilot plant tests were carried out in a 100 L reaction vessel. Both average yield and fatty acid methyl esters (FAME) content reached more than 96.50% under the optimum reaction conditions of the pilot plant tests designed with an oil/methanol molar ratio of 1 : 10, catalyst concentration of 1.00%, and reaction time of 3 h at reflux temperature. In addition, analysis shows that the quality of biodiesel meets the standard EN 14214. | Rui WANG Song YANG Shitao YIN Baoan SONG Pinaki SBHADURY Wei XUE Shuwei TAO Zhaohui JIA Da LIU Liang GAO | 2008 | Frontiers of Chemical Science and Engineering2008，2，4： | 0 |
| 18 | Effect of Inter Stock ‘Zhong ai 1hao'on the Structure of Spindle-shaped 'Huangguan' Pear Trees显示文摘In order to investigate the effect of dwarfing inter stock on the structure of pear trees,investigations were made to the tree and group structure of the 4-year-old spindle-shaped‘Huangguan'pear grafted with vigorous stock( Pyrus betulaefolia stock) and that grafted with the dwarfing inter stock‘Zhong ai 1 hao'( P. betulaefolia rootstock). The results showed that the 4-year-old‘Huangguan'pear trees grafted with the dwarfing inter stock‘ Zhong ai 1 hao'were 2. 87 m high on average,with 70. 70% of short braches,converted into 21 016. 0 branches per 667 m^2,840. 64 m^2 of leaf area per 667 m^2 with the leaf area coefficient of 1. 75.On the other hand,for the‘Huangguan'trees grafted with vigorous stocks,the average tree height was 3. 17 m,and the short branch proportion was 63. 20%,converted into 15 806. 4 branches per 667 m^2,719. 28 m^2 of leaf area per 667 m^2 with the leaf area coefficient of 1. 55. Therefore,the use of dwarfing inter stock‘Zhong ai 1 hao'had significant dwarfing effect on‘Huangguan'pear trees,which also showed significant yield increasing effect. | Shuwei WEI Xiaochang DONG Ran DONG Kun RAN Hongwei WANG Shaomin WANG | 2019 | Agricultural Biotechnology2019，8，1： | 0 |
| 19 | A randomized controlled trial to evaluate efficacy and safety of early conversion to a low-dose calcineurin inhibitor combined with sirolimus in renal transplant patients显示文摘Background:The calcineurin inhibitor(CNI)-based immune maintenance regimen that is commonly used after renal transplantation has greatly improved early graft survival after transplantation;however,the long-term prognosis of grafts has not been significantly improved.The nephrotoxicity of CNI drugs is one of the main risk factors for the poor long-term prognosis of grafts.Sirolimus(SRL)has been employed as an immunosuppressant in clinical practice for over 20 years and has been found to have no nephrotoxic effects on grafts.Presently,the regimen and timing of SRL application after renal transplantation vary,and clinical data are scarce.Multicenter prospective randomized controlled studies are particularly rare.This study aims to investigate the effects of early conversion to a low-dose CNI combined with SRL on the long-term prognosis of renal transplantation.Methods:Patients who receive four weeks of a standard regimen with CNI+mycophenolic acid(MPA)+glucocorticoid after renal transplantation in multiple transplant centers across China will be included in this study.At week 5,after the operation,patients in the experimental group will receive an additional administration of SRL,a reduction in the CNI drug doses,withdrawal of MPA medication,and maintenance of glucocorticoids.In addition,patients in the control group will receive the maintained standard of care.The patients’vital signs,routine blood tests,routine urine tests,blood biochemistry,serum creatinine,BK virus(BKV)/cytomegalovirus(CMV),and trough concentrations of CNI drugs and SRL at the baseline and weeks 12,24,36,48,72,and 104 after conversion will be recorded.Patient survival,graft survival,and estimated glomerular filtration rate will be calculated,and concomitant medications and adverse events will also be recorded.Conclusion:The study data will be utilized to evaluate the efficacy and safety of early conversion to low-dose CNIs combined with SRL in renal transplant patients. | Xiang Zheng Weijie Zhang Hua Zhou Ronghua Cao Zhangfei Shou Shuwei Zhang Ying Cheng Xuchun Chen Chenguang Ding Zuofu Tang Ning Li Shaohua Shi Qiang Zhou Qiuyuan Chen Gang Chen Zheng Chen Peijun Zhou Xiaopeng Hu Xiaodong Zhang Ning Na Wei Wang | 2022 | Chinese Medical Journal2022，，13： | 0 |
| 20 | 大功率高电压电动伺服系统在运载火箭上的应用研究显示文摘The 30 kW high-power electric servo system used in the solid booster of the Long March 6 A(LM-6 A)launch vehicle is introduced,and the function,composition of the system as well as its constituent equipments are detailed.To solve the problem of out-of-tolerance in the system dynamic characteristics,an advanced correction network algorithm architecture and double notch filter were designed.Experimental verification was conducted to prove that the dynamic characteristics requirement under multiple operating conditions could be met. | FENG Wei CUI Yebing WANG Yaoyao YU Ge SONG Shuwei CHEN Shuheng GU Dawei | 2022 | Aerospace China2022，23，2： | 0 |
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