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| 1 | Reversibility of minimal hepatic encephalopathy following liver transplantation in Egyptian cirrhotic patients显示文摘AIM To evaluate the reversibility of minimal hepatic encephalopathy(MHE) following liver transplantation(LT) in Egyptian cirrhotic patients. METHODS This prospective study included twenty patients with biopsy-proven liver cirrhosis listed for LT and twenty ageand sex-matched healthy control subjects. All underwent neuro-psychiatric examination, laboratory investigations, radiological studies and psychometric tests including trail making test A(TMT A), TMT B, digit symbol test and serial dotting test. The psychometric hepatic encephalopathy score(PHES) was calculated for patients to diagnose MHE. Psychometric tests were repeated six months following LT in the cirrhotic patient group. RESULTS Before LT, psychometric tests showed highly significant deficits in cirrhotic patients in comparison to controls(P < 0.001). There was a statistically significant improvement in test values in the patient group after LT; however, their values were still significantly worse than those of the controls(P < 0.001). The PHES detected MHE in 16 patients(80%) before LT with a median value of -7 ± 3.5. The median PHES value was significantly improved following LT, reaching-4.5 ± 5(P < 0.001), and the number of patients with MHE decreased to 11(55%). The pre-transplant model for end-stage liver disease(MELD) score ≥ 15 was significantly related to the presence of post-transplant MHE(P = 0.005). More patients in whom reversal of MHE was observed had a pre-transplant MELD score < 15.CONCLUSION Reversal of MHE in cirrhotic patients could be achieved by LT, especially in those with a MELD score < 15. | Mahmoud A Osman Moataz M Sayed Khaled A Mansour Shereen A Saleh Wesam A Ibrahim Sara M Abdelhakam Mohamed Bahaa Wael A Yousry Hosam S Elbaz Reginia N Mikhail Azza M Hassan Ehab H Elsayed Dalia A Mahmoud | 2016 | World Journal of Hepatology2016，8，30： | 11 |
| 2 | Simulation of the response of base-isolated buildings under earthquake excitations considering soil flexibility显示文摘The accurate analysis of the seismic response of isolated structures requires incorporation of the flexibility of supporting soil.However,it is often customary to idealize the soil as rigid during the analysis of such structures.In this paper,seismic response time history analyses of base-isolated buildings modelled as linear single degree-of-freedom(SDOF) and multi degree-of-freedom(MDOF) systems with linear and nonlinear base models considering and ignoring the flexibility of supporting soil are conducted.The flexibility of supporting soil is modelled through a lumped parameter model consisting of swaying and rocking spring-dashpots.In the analysis,a large number of parametric studies for different earthquake excitations with three different peak ground acceleration(PGA) levels,different natural periods of the building models,and different shear wave velocities in the soil are considered.For the isolation system,laminated rubber bearings(LRBs) as well as high damping rubber bearings(HDRBs) are used.Responses of the isolated buildings with and without SSI are compared under different ground motions leading to the following conclusions:(1) soil flexibility may considerably influence the stiff superstructure response and may only slightly influence the response of the flexible structures;(2) the use of HDRBs for the isolation system induces higher structural peak responses with SSI compared to the system with LRBs;(3) although the peak response is affected by the incorporation of soil flexibility,it appears insensitive to the variation of shear wave velocity in the soil;(4) the response amplifications of the SDOF system become closer to unit with the increase in the natural period of the building,indicating an inverse relationship between SSI effects and natural periods for all the considered ground motions,base isolations and shear wave velocities;(5) the incorporation of SSI increases the number of significant cycles of large amplitude accelerations for all the stories,especially for earthquakes with low and moderate PGA levels;and(6) buildings with a linear LRB base-isolation system exhibit larger differences in displacement and acceleration amplifications,especially at the level of the lower stories. | Sayed Mahmoud Per-Erik Austrell Robert Jankowski | 2012 | Earthquake Engineering and Engineering Vibration2012，11，3： | 9 |
| 3 | 不同铸造工艺制备A356-CNT纳米复合材料的摩擦学行为(英文)显示文摘研究液态成形和半固态成形法制备的A356 铝合金整体铸件和A356-CNT 纳米复合铸造件的摩擦学行为。采用熔体搅拌、流变铸造、搅拌铸造、复合铸造等不同工艺制备样品。研究碳纳米管(CNTs)的加入、铸造工艺和施加载荷对磨损性能和磨损机理的影响。结果表明,添加碳纳米管显著降低了纳米复合材料的磨损量、磨损率和摩擦因数。铸造工艺由液态成形变为半固态成形,和初相含量的增加是提高合金尤其是纳米复合合金样品耐磨性能的两个主要因素。此外,研究还发现液态成形和半固态成形两种方法制备的整体铸件其主要磨损机理分别是粘着磨损和剥层磨损。然而,无论制备工艺如何,磨粒磨损是纳米复合材料的主要磨损机理。 | Benyamin ABBASIPOUR Behzad NIROUMAND Sayed Mahmoud MONIR VAGHEFI Mohammad ABEDI | 2019 | Transactions of Nonferrous Metals Society of China2019，29，10： | 9 |
| 4 | Multiple linear regression, artificial neural network, and fuzzy logic prediction of 28 days compressive strength of concrete显示文摘评估在里面然而,借助于核心的压缩力量从变硬的水泥割了的 situ 水泥作为最平常的方法被承认自从它被象不同混合图案那样的许多因素影响,预言水泥的压缩力量是很困难的,混合的方法,治好条件,压缩,等等。在这份报纸,就试验性的结果而言,多重线性回归模型( MLR )的三个不同模型,人工的神经网络( ANN ),和适应neuro模糊的推理系统( ANFIS )被建立,训练,并且为与 173 个不同混合图案预言水泥的 28 天压缩的力量在 Matlab 编程环境以内测试了。最后,这三个模型与对方相比并且导致 ANN 和 ANFIS 模型使我们能然而,可靠地与不同混合图案评估水泥的压缩力量的事实因为在具体混合参数之间的非线性的关系,多重线性回归模型不在这个区域是足够可行的。最后,为具体压缩力量预言上的参数的二个不同集合的敏感分析(SA ) 被执行。 | Faezehossadat KHADEMI Mahmoud AKBARI Sayed Mohammadmehdi JAMAL Mehdi NIKOO | 2017 | Frontiers of Structural and Civil Engineering2017，11，1： | 8 |
| 5 | 模具几何形状对AZ80镁合金非等通道横向挤压的影响(英文)显示文摘非等通道横向挤压(NECLE)是一种新工艺,与等通道横向挤压(ECLE)相比,采用非等通道横向挤压工艺可以得到更加细化的晶粒。对该模具设计工艺进行了数值模拟和实验研究。发现数值模拟和实验结果之间存在良好的相关性,并进行了全面的有限元分析。考虑了不同的模具几何参数,并研究了这些参数对诱导塑性应变、应力分布、速度场和载荷的影响。结果表明,当具有一组合适的模具几何参数时,与等通道横向挤压相比,采用非等通道横向挤压工艺可以得到高诱导有效应变和更均匀应变分布。 | Faramarz FERESHTEH-SANIEE Mohammad ASGARI Mahmoud BARATI Sayed Mahmoud PEZESHKI | 2014 | Transactions of Nonferrous Metals Society of China2014，24，10： | 4 |
| 6 | Occult hepatitis B virus infection among Egyptian blood donors显示文摘AIM:To identify blood donors with occult hepatitis B virus(HBV) infection(OBI) to promote safe blood donation.METHODS:Descriptive cross sectional study was conducted on 3167 blood donors negative for hepatitis B surface antigen(HBsAg),hepatitis C antibody(HCV Ab) and human immunodeficiency virus Ab.They were subjected to the detection of alanine aminotransferase(ALT) and aspartate transaminase(AST) and screening for anti-HBV core antibodies(total) by two different techniques;[Monoliza antibodies to hepatitis B core(Anti-HBc) Plus-Bio-Rad] and(ARC-HBc total-ABBOT).Positive samples were subjected to quantitative detection of antibodies to hepatitis B surface(anti-HBs)(ETI-AB-AUK-3,Dia Sorin-Italy).Serum anti-HBs titers > 10 IU/L was considered positive.Quantitative HBV DNA by real time polymerase chain reaction(PCR)(QIAGEN-Germany) with 3.8 IU/mL detection limit was estimated for blood units with negative serum anti-HBs and also for 32 whose anti-HBs serum titers were > 1000 IU/L.Also,265 recipients were included,34 of whom were followed up for 3-6 mo.Recipients were investigated for ALT and AST,HBV serological markers:HBsAg(ETI-MAK-4,Dia Sorin-Italy),anti-HBc,quantitative detection of anti-HBs and HBV-DNA.RESULTS:525/3167(16.6%) of blood units were positive for total anti-HBc,64% of those were antiHBs positive.Confirmation by ARCHITECT anti-HBc assay were carried out for 498/525 anti-HBc positive samples,where 451(90.6%) confirmed positive.Reactivity for anti-HBc was considered confirmed only if two positive results were obtained for each sample,giving an overall prevalence of 451/3167(14.2%) for total anti-HBc.HBV DNA was quantified by real time PCR in 52/303(17.2%) of anti-HBc positive blood donors(viral load range:5 to 3.5 x 105 IU/mL) with a median of 200 IU/mL(mean:1.8 x 104 ± 5.1 x 104 IU/mL).AntiHBc was the only marker in 68.6% of donors.Univariate and multivariate logistic analysis for identifying risk factors associated with anti-HBc and HBV-DNA positivity among blood donors showed that age above thirty and marriage were the most significant risk factors for prediction of anti-HBc positivity with AOR 1.8(1.4-2.4) and 1.4(1.0-1.9) respectively.Other risk factors as gender,history of blood transfusion,diabetes mellitus,frequent injections,tattooing,previous surgery,hospitalization,Bilharziasis or positive family history of HBV or HCV infections were not found to be associated with positive anti-HBc antibodies.Among anti-HBc positive blood donors,age below thirty was the most significant risk factor for prediction of HBV-DNA positivity with AOR 3.8(1.8-7.9).According to HBV-DNA concentration,positive samples were divided in two groups;group one with HBV-DNA ≥ 200 IU/mL(n = 27) and group two with HBV-DNA < 200 IU/mL(n = 26).No significant difference was detected between both groups as regards mean age,gender,liver enzymes or HBV markers.Serological profiles of all followed up blood recipients showed that,all were negative for the studied HBV markers.Also,HBV DNA was not detected among studied recipients,none developed post-transfusion hepatitis(PTH) and the clinical outcome was good.CONCLUSION:OBI is prevalent among blood donors.Nucleic acid amplification/HBV anti core screening should be considered for high risk recipients to eliminate risk of unsafe blood donation. | Zeinab N Said Manal H El Sayed Iman I Salama Enas K Aboel-Magd Magda H Mahmoud Maged El Setouhy Faten Mouftah Manal B Azzab Heidi Goubran Amal Bassili Gamal E Esmat | 2013 | World Journal of Hepatology2013，5，2： | 4 |
| 7 | Correlation between corneal demarcation line depth in epithelium-off and trans-epithelium accelerated corneal cross linking and keratoconus progression显示文摘AIM:To compare corneal demarcation line(DL)depth in both accelerated epithelium-off and trans-epithelium cross linking(CXL)using anterior segment optical coherence tomography(AS-OCT)and its relation to maximum keratometry(Kmax)progression in both techniques.METHODS:A prospective comparative interventional study where patients with mild to moderate keratoconus(KC)were classified into two groups:accelerated epitheliumoff and trans-epithelium CXL based on corneal pachymetry.Assessment of corneal DL depth was carried out after 3mo by AS-OCT.Kmax readings were evaluated after one year follow up using the Scheimpflug imaging system.RESULTS:Study included 74 eyes of 44 patients.Group A underwent epithelium-off CXL(41 eyes),while Group B underwent trans-epithelium CXL(33 eyes).At 3mo follow up,mean corneal DL depth in Group A was 219.9±58.4μm while in Group B was 127.2±7.8μm(P<0.05).The mean Kmaxchangedfrom51.9±3.9to51.3±4.2dioptersin Group A and from 53.1±4.1 to 53.6±5 diopters in Group B with insignificant difference in Kmax changes in either group(P>0.05).In addition,no significant change in corneal pachymetry was found in both groups(meanchange at 1y:6.4±4.7 and-10.1±2.3μm in Groups A and B respectively).CONCLUSION:Despite a significantly deeper corneal DL depth created by accelerated epithelium-off CXL technique compared to accelerated trans-epithelium CXL,there is no significant impact on keratoconus progression. | Mahmoud Abdel-Radi Zeiad Eldaly Hazem Abdelmotaal Reham Abdelrahman Mohamed Sayed Kamel Soliman | 2020 | International Journal of Ophthalmology(English edition)2020，13，6： | 2 |
| 8 | The pharmacokinetics of the prostaglandin E1 analogue misoprostol in plasma and colostrum after postpartum oral administration显示文摘 | Hany Abdel-Aleem José Villar A Metin Gülmezoglu Sayed A Mostafa Alaa A Youssef Mahmoud Shokry Bernhard Watzer | 2002 | European Journal of Obstetrics and Gynecology2002，，1： | 2 |
| 9 | Early detection of hepatocellular carcinoma co-occurring with hepatitis C virus infection: A mathematical model显示文摘AIM: To develop a mathematical model for the early detection of hepatocellular carcinoma(HCC) with a panel of serum proteins in combination with α-fetoprotein(AFP).METHODS: Serum levels of interleukin(IL)-8, soluble intercellular adhesion molecule-1(s ICAM-1), soluble tumor necrosis factor receptor Ⅱ(s TNF-RⅡ), proteasome, and β-catenin were measured in 479 subjects categorized into four groups:(1) HCC concurrent with hepatitis C virus(HCV) infection(n = 192);(2) HCV related liver cirrhosis(LC)(n = 96);(3) Chronic hepatitis C(CHC)(n = 96); and(4) Healthy controls(n = 95). The R package and different modules for binary and multi-class classifiers based on generalized linear models were used to model the data. Predictive power was used to evaluate the performance of the model. Receiver operating characteristic curve analysis over pairs of groups was used to identify the best cutoffs differentiating the different groups. RESULTS: We revealed mathematical models, based on a binary classifier, made up of a unique panel of serum proteins that improved the individual performance of AFP in discriminating HCC patients from patients with chronic liver disease either with or without cirrhosis. We discriminated the HCC group from the cirrhotic liver group using a mathematical model(-11.3 + 7.38 × Prot + 0.00108 × s ICAM + 0.2574 ×β-catenin + 0.01597 × AFP) with a cutoff of 0.6552, which achieved 98.8% specificity and 89.1% sensitivity. For the discrimination of the HCC group from the CHC group, we used a mathematical model [-10.40 + 1.416 × proteasome + 0.002024 × IL + 0.004096 × s ICAM-1 +(4.251 × 10-4) × s TNF + 0.02567 ×β-catenin + 0.02442 × AFP] with a cutoff 0.744 and achieved 96.8% specificity and 89.7% sensitivity. Additionally, we derived an algorithm, based on a binary classifier, for resolving the multi-class classification problem by using three successive mathematical model predictions of liver disease status. CONCLUSION: Our proposed mathematical model may be a useful method for the early detection of different statuses of liver disease co-occurring with HCV infection. | Abdel-Rahman Nabawy Zekri Amira Salah El-Din Youssef Yasser Mabrouk Bakr Reham Mohamed Gabr Ola Sayed Ahmed Mostafa Hamed Elberry Ahmed Mahmoud Mayla Mohamed Abouelhoda Abeer A Bahnassy | 2016 | World Journal of Gastroenterology2016，22，16： | 2 |
| 10 | Preparation and comparative evaluation of sustained release metoclopramide hydrochloride matrix tablets显示文摘 | Sayed I. Abdel-Rahman Gamal M. Mahrous Mahmoud El-Badry | 2009 | Saudi Pharmaceutical Journal2009，，4： | 1 |
| 11 | Corneal topographic changes and surgically induced astigmatism following combined phacoemulsification and 25-gauge vitrectomy显示文摘● AIM: To evaluate corneal topographic changes and surgically induced astigmatism(SIA) after combined phacoemulsification and 25-gauge transconjunctival sutureless vitrectomy(25-G TSV).● METHODS: A retrospective study on 96 eyes of 87 patients who underwent combined phacoemulsification and 25-G TSV. The different topographic parameters and SIA were analyzed pre- and postoperatively. ● RESULTS: There was no significant changes in corneal topographic parameters at different follow up periods. Only surface regularity index changed significantly in the 2^(nd) postoperative week and then returned to baseline values thereafter. Mean SIA gradually decreased to reach 0.12 D by the 6^(th) postoperative month. ● CONCLUSION: Corneal surface and astigmatic changes are insignificant in either early or late postoperative periods following combined phacoemulsification and 25-G TSV. The SIA was the minimum among previous reports on sutureless vitrectomy alone or combined with phacoemulsification. Improvement of SIA did not stop at the 3^(rd) postoperative month but it continued till the 6^(th) month postoperatively. | Khulood Mohammed Sayed Mahmoud M.Farouk Takashi Katome Toshihiko Nagasawa Takeshi Naito Yoshinori MitamurA | 2017 | International Journal of Ophthalmology(English edition)2017，10，1： | 1 |
| 12 | Clinical implications of adiponectin and inflammatory biomarkers in type 2 diabetes mellitus显示文摘 | Swellam M Sayed Mahmoud And M Abdel-Fatah Ali A | 2009 | Dis Markers2009，27，6： | 1 |
| 13 | Repro- ductive biomarkers to identify endocrine disruption in Clarias gariepinus exposed to 4-nonylphenol 显示文摘 | Sayed AeI-D Mahmoud U M Mekkawy I A | 2012 | Eco- toxicology and Environmental Safety2012，78，： | 1 |
| 14 | Surface properties and thermodynamic parameters of some sugar - based ethoxylated amine surfactants 1 : Synthesis, characterization, and demulsification efficiency 显示文摘 | MANAR EL - SAYED ABDEL - RAOUF ABDUL - RAHEIM MAHMOUD ABDUL - RAHEIM ABDEL - AZIM AHMED ABDEL - AZIM | 2011 | Journal of Surfactants and Detergents2011，14，1： | 1 |
| 15 | Prognostic factors for extracorporeal shock‐wave lithotripsy of ureteric stones A multivariate analysis study显示文摘 | Mohamed Abdel‐Khalek Khaled Z. Sheir Emad Elsobky Saied Showkey Mahmoud Kenawy | 2003 | Scandinavian Journal of Urology and Nephrology2003，，5： | 1 |
| 16 | The role of platelets CD40 ligand(CD154)in acute coronary syndromes显示文摘 | Abu el-Makrem MA Mahmoud YZ Sayed D | 2009 | Thrombesis Research2009，124，6： | 1 |
| 17 | Polyphenolic metabolites of Rhamnus disperma显示文摘 | Marzouk Mohamed S El-Toumy Sayed A A Merfort Irmgard Nawwar Mahmoud A M | 1999 | Phytochemistry1999，52，5： | 1 |
| 18 | Aberrant methylation of APC amt RAR132 genes in breast cancer patients 显示文摘 | Swellam M Abdehnaksoud MD Sayed Mahmoud M | 2015 | IUBMB Life2015，67，1： | 1 |
| 19 | Reproductive biomarkers to identify endocrine disruption in Clarias gariepinus exposed to 4- nonylphenol显示文摘 | Sayed AD Mahmoud UM Mekkawy IA | 2012 | Ecotoxicol Environ Saf2012，78，： | 1 |
| 20 | Synthesis of Some New Diazo Disperse Dyes and Their Application on Dyeing of Polyester显示文摘 | Ahmed Zaky Sayed Mahmoud Sayed Aboul-Fetouh Hesham Sayed Nassar | 2011 | Journal of Chemistry and Chemical Engineering2011，5，2： | 1 |
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