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| 1 | Reversibility of minimal hepatic encephalopathy following liver transplantation in Egyptian cirrhotic patients显示文摘AIM To evaluate the reversibility of minimal hepatic encephalopathy(MHE) following liver transplantation(LT) in Egyptian cirrhotic patients. METHODS This prospective study included twenty patients with biopsy-proven liver cirrhosis listed for LT and twenty ageand sex-matched healthy control subjects. All underwent neuro-psychiatric examination, laboratory investigations, radiological studies and psychometric tests including trail making test A(TMT A), TMT B, digit symbol test and serial dotting test. The psychometric hepatic encephalopathy score(PHES) was calculated for patients to diagnose MHE. Psychometric tests were repeated six months following LT in the cirrhotic patient group. RESULTS Before LT, psychometric tests showed highly significant deficits in cirrhotic patients in comparison to controls(P < 0.001). There was a statistically significant improvement in test values in the patient group after LT; however, their values were still significantly worse than those of the controls(P < 0.001). The PHES detected MHE in 16 patients(80%) before LT with a median value of -7 ± 3.5. The median PHES value was significantly improved following LT, reaching-4.5 ± 5(P < 0.001), and the number of patients with MHE decreased to 11(55%). The pre-transplant model for end-stage liver disease(MELD) score ≥ 15 was significantly related to the presence of post-transplant MHE(P = 0.005). More patients in whom reversal of MHE was observed had a pre-transplant MELD score < 15.CONCLUSION Reversal of MHE in cirrhotic patients could be achieved by LT, especially in those with a MELD score < 15. | Mahmoud A Osman Moataz M Sayed Khaled A Mansour Shereen A Saleh Wesam A Ibrahim Sara M Abdelhakam Mohamed Bahaa Wael A Yousry Hosam S Elbaz Reginia N Mikhail Azza M Hassan Ehab H Elsayed Dalia A Mahmoud | 2016 | World Journal of Hepatology2016，8，30： | 11 |
| 2 | Clinical implications of adiponectin and inflammatory biomarkers in type 2 diabetes mellitus显示文摘 | Swellam M Sayed Mahmoud And M Abdel-Fatah Ali A | 2009 | Dis Markers2009，27，6： | 1 |
| 3 | Repro- ductive biomarkers to identify endocrine disruption in Clarias gariepinus exposed to 4-nonylphenol 显示文摘 | Sayed AeI-D Mahmoud U M Mekkawy I A | 2012 | Eco- toxicology and Environmental Safety2012，78，： | 1 |
| 4 | Polyphenolic metabolites of Rhamnus disperma显示文摘 | Marzouk Mohamed S El-Toumy Sayed A A Merfort Irmgard Nawwar Mahmoud A M | 1999 | Phytochemistry1999，52，5： | 1 |
| 5 | Aberrant methylation of APC amt RAR132 genes in breast cancer patients 显示文摘 | Swellam M Abdehnaksoud MD Sayed Mahmoud M | 2015 | IUBMB Life2015，67，1： | 1 |
| 6 | Influence of Deposition Temperature on the Properties of Sprayed Cul~ Thin Films显示文摘 | Sayed M H Mahmoud FA Boshta M | 2012 | J Mater Sci: Mater Electron2012，23，： | 1 |
| 7 | Influence of deposition temperature on the properties of sprayedCuInS2 thin films 显示文摘 | Sayed M H Mahmoud F A Boshta M | 2012 | Journal of Materials Science-Materials in Electronics2012，27，17： | 1 |
| 8 | The role of platelets CD40 ligand (CD154) in acute coronary syndromes显示文摘 | Abu el-Makrem M A Mahmoud Y Z Sayed D | | 0，，06： | 1 |
| 9 | Biliary fistula and late recurrence of liver hydatid cyst:Role of cystobiliary communication:A prospective multicenter study显示文摘BACKGROUND Hydatid cyst disease(HCD)is common in certain locations.Surgery is associated with postoperative biliary fistula(POBF)and recurrence.The primary aim of this study was to identify whether occult cysto-biliary communication(CBC)can predict recurrent HCD.The secondary aim was to assess the role of cystic fluid bilirubin and alkaline phosphatase(ALP)levels in predicting POBF and recurrent HCD.AIM To identify whether occult CBC can predict recurrent HCD.The secondary aim was to assess the role of cystic fluid bilirubin and ALP levels in predicting POBF and recurrent HCD.METHODS From September 2010 to September 2016,a prospective multicenter study was undertaken involving 244 patients with solitary primary superficial stage cystic echinococcosis 2 and cystic echinococcosis 3b HCD who underwent laparoscopic partial cystectomy with omentoplasty.Univariable logistic regression analysis assessed independent factors determining biliary complications and recurrence.RESULTS There was a highly statistically significant association(P≤0.001)between cystic fluid biochemical indices and the development of biliary complications(of 16 patients with POBF,15 patients had high cyst fluid bilirubin and ALP levels),where patients with high bilirubin-ALP levels were 3405 times more likely to have biliary complications.There was a highly statistically significant association(P≤0.001)between biliary complications,biochemical indices,and the occurrence of recurrent HCD(of 30 patients with recurrent HCD,15 patients had high cyst fluid bilirubin and ALP;all 16 patients who had POBF later developed recurrent HCD),where patients who developed biliary complications and high bilirubin-ALP were 244.6 and 214 times more likely to have recurrent hydatid cysts,respectively.CONCLUSION Occult CBC can predict recurrent HCD.Elevated cyst fluid bilirubin and ALP levels predicted POBF and recurrent HCD. | Tamer A A M Habeeb Mauro Podda Boris Tadic Vishal G Shelat Yaman Tokat Mohamed Ibrahim Abo Alsaad Abd-Elfattah Kalmoush Mohammed Shaaban Nassar Fawzy Metwally Mustafa Mahmoud Hassib Morsi Badawy Mohamed Sobhy Shaaban Tarek Zaghloul Mohamed Mohammed Ibrahim El Sayed Henish Hamdi Elbelkasi Mahmoud Abdou Yassin Abdelshafy Mostafa Amr Ibrahim Waleed A-Abdelhady TamerMohamed Elshahidy Mohamed Ibrahim Mansour Adel Mahmoud Moursi Mohamed Abdallah Zaitoun EhabShehata Abd-Allah Ashraf Abdelmonem Elsayed Rasha S Elsayed Ahmed M Yehia Amr Abdelghani Mohamed Negm Heba Alhussein Abo-Alella Mostafa M Elaidy | 2023 | World Journal of Methodology2023，13，4： | 0 |
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