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| 1 | Interstitial cells of Cajal, the Maestro in health and disease显示文摘Interstitial cells of Cajal (ICC) are important players in the symphony of gut motility. They have a very signif icant physiological role orchestrating the normal peristaltic activity of the digestive system. They are the pacemaker cells in gastrointestinal (GI) muscles. Absence, reduction in number or altered integrity of the ICC network may have a dramatic effect on GI system motility. More understanding of ICC physiology will foster advances in physiology of gut motility which will help in a future breakthrough in the pharmacological interventions to restore normal motor function of GI tract. This mini review describes what is known about the physiologic function and role of ICCs in GI system motility and in a variety of GI system motility disorders. | Randa M Mostafa Yasser M Moustafa Hosam Hamdy | 2010 | World Journal of Gastroenterology2010，16，26： | 56 |
| 2 | p16 promoter hypermethylation:A useful serum marker for early detection of gastric cancer显示文摘AIM: To determine p16 promoter hypermethylation in gastric tumoral tissue and serum samples, its impact on p16-protein expression, and correlation with clinical and histological features. METHODS: Samples were obtained from 52 histologically confirmed cases of gastric adenocarcinoma. Gastric tissue and serum of 50 age- and sex-matched individuals with normal gastroscopy and biopsy were obtained as control samples. Methylation-specific polymerase chain reaction (MSP) was used to evaluate methylation status of p16 promoter. p16-protein expression was analyzed by immunohistochemical staining on paraffin-embedded sections. RESULTS: Methylation was detected in 44.2% (23/52) of tumoral tissues. 60.9% of them were also methylated in serum, i.e., 26.9% of all patients (14/52). Methylation was not detected in tissue and sera of control samples. p16-protein expression was decreased in 61.5% of cases (32/52), and was significantly associated with promoter hypermethylation (P < 0.001). Methylation was significantly more frequent in higher pathological grades (P < 0.05). Methylation was not associated with other clinicopathological features and environmental factors including H pylori infection and smoking. CONCLUSION: p16 promoter hypermethylation is an important event in gastric carcinogenesis. It is the principle mechanism of p16 gene silencing. It is related to malignant tumor behavior. Detection of DNA methylation in serum may be a biomarker for early detection of gastric cancer. | Mohammad Reza Abbaszadegan Omeed Moaven Hamid Reza Sima Kamran Ghafarzadegan Azadeh A'rabi Mohammad Naser Forghani Hamid Reza Raziee Ali Mashhadinejad Mostafa Jafarzadeh Ehsan Esmaili-Shandiz Ezzat Dadkhah | 2008 | World Journal of Gastroenterology2008，14，13： | 50 |
| 3 | Expression of cell adhesion molecule CD44 in gastric adenocarcinoma and its prognostic importance显示文摘AIM: To evaluate the relation of cluster of differentiation 44 (CD44) expression with clinicopathological features of gastric adenocarcinoma, and also its effect on prognosis with an emphasis on the differences between intestinal and diffuse types. METHODS: From 2000 to 2006, 100 patients with gastric adenocarcinoma, who had undergone total or subtotal gastrectomy without any prior treatment, were studied. Haematoxylin & eosin (HE) staining was used for histological evaluation, including the type (Lauren's classifi cation) and grading of the tumor. The expression of CD44 in the gastric adenocarcinoma mucosa and the adjacent mucosa were determined by immunohistochemistry. The survival analysis was obtained using the Kaplan-Meier test. RESULTS: Of 100 patients, 74 (74%) patients were male. The tumors were categorized as intestinal type (78%) or diffuse type (22%). Sixty-five percent of patients were CD44-positive. CD44 expression was not detected in normal gastric mucosa. Rather, CD44 was more commonly expressed in the intestinal subtype (P = 0.002). A signifi cant relation was seen between the grade of tumor and the expression of CD44 (P = 0.014). The survival analysis showed a poor prognosis of patients with CD44-positive tumors (P = 0.008); and this was more prominent in the intestinal (P = 0.001) rather than diffuse type. CONCLUSION: Cell adhesion molecule CD44 is highly expressed in gastric adenocarcinoma. CD44 expression is correlated with a poor prognosis in patients with the intestinal type of gastric adenocarcinoma. CD44 can, therefore, be utilized as a prognostic marker for this group of patients. | Kamran Ghaffarzadehgan Mostafa Jafarzadeh Hamid Reza Raziee Hamid Reza Sima Ehsan Esmaili-Shandiz Hanieh Hosseinnezhad Ali Taghizadeh Kermani Omeed Moaven Maryam Bahrani | 2008 | World Journal of Gastroenterology2008，14，41： | 18 |
| 4 | Seminal plasma anti-Müllerian hormone level correlates with semen parameters but does not predict success of testicular sperm extraction (TESE)显示文摘瞄准:估计精液的血浆 anti-Muellerian 在肥沃、不肥沃的男性的荷尔蒙(AMH ) levalrelationships。方法:84 个男盒子被学习并且把组划分了成四:肥沃的 normozoospermia (n = 16 ) , oligoastheno-teratozoospermia (n = 15 ) ,妨碍的精子缺乏(OA )(n = 13 ) 并且非妨碍的精子缺乏(NOA )(n = 40 ) 。Conventionalsemen 分析为所有情况被做。阴囊的活体检视在 NOA 情况中为阴囊的精子抽取(TESE ) 用完了组织病理学说和新鲜织物检查。NOA 组根据 TESE 结果被细分进失败的 TESE (n = 19 ) 并且成功的 TESE (n = 21 ) 。Seminalplasma AMH 被酶估计连接免疫吸着剂试金(ELISA ) 和浆液小囊的刺激荷尔蒙(FSH ) 仅仅由放射性免疫测定(RIA ) 在 NOA 情况中被估计。结果:Meanseminal AMH 比在有意义的 oligoasthenoteratozoospermia 在肥沃的组是显著地更高的(41.5 ± 10.9 pmol/L 对 30.5 ± 10.3 pmol/L, P <
0.05 ) 。精液的 AMH 没在任何 OA 病人被检测。精液的 AMH 与阴囊的体积断然被相关( r = 0.329 , P =0.005 ),精子计数( r = 0.483 , P = 0.007 ),精子活动性百分比( r = 0.419 , P = 0.021 )并且否定地与精子反常形式百分比( r =-0.413, p = 0.023 )。不重要的关联与年龄是明显的(r =-0.155, P = 0.414 ) 并且血浆 FSH (r =-0.014, P = 0.943 ) 。在 NOA 情况中,精液的 AMH 在 23/40 情况中是可检测的,他们中的 14 个是成功的 TESE (57.5%) 并且在 17/40 情况中是无法发现的,他们中的 10 个是失败的 TESE (58.2%) 。结论:精液的 plasmaAMH 是在所有 OA 盒子中是不在的一个绝对阴囊的标记。然而,精液的 AMH 在 NOA 情况中为成功的阴囊的精子检索有差的可预测性。 | Taymour Mostafa Medhat K. Amer Guirgis Abdel-Malak Taha Abdel Nsser Wael Zohdy Shedeed Ashour Dina El-Gayar Hosam H. Awad | 2007 | Asian Journal of Andrology2007，9，2： | 17 |
| 5 | Trends and outcomes of pancreaticoduodenectomy for periampullary tumors: A 25-year single-center study of 1000 consecutive cases显示文摘AIM To evaluate the evolution, trends in surgical approaches a n d r e c o n s t r u c t i o n t e c h n i q u e s, a n d i m p o r t a n t lessons learned from performing 1000 consecutive pancreaticoduodenectomies(PDs) for periampullary tumors.METHODS This is a retrospective review of the data of all patients who underwent PD for periampullary tumor during the period from January 1993 to April 2017. The data were categorized into three periods, including early period(1993-2002), middle period(2003-2012), and late period(2013-2017).RESULTS The frequency showed PD was increasingly performed after the year 2000. With time, elderly, cirrhotic and obese patients, as well as patients with uncinate process carcinoma and borderline tumor were increasingly selected for PD. The median operative time and postoperative hospital stay decreased significantly over the periods. Hospital mortality declined significantly, from 6.6% to 3.1%. Postoperative complications significantly decreased, from 40% to 27.9%. There was significant decrease in postoperative pancreatic fistula in the second 10 years, from 15% to 12.7%. There was a significant improvement in median survival and overall survival among the periods.CONCLUSION Surgical results of PD significantly improved, with mortality rate nearly reaching 3%. Pancreatic reconstruction following PD is still debatable. The survival rate was also improved but the rate of recurrence is still high, at 36.9%. | ayman el nakeeb waleed askar ehab atef ehab el hanafy ahmad m sultan tarek salah ahmed shehta mohamed el sorogy emad hamdy mohamed el hemly ahmed a el-geidi tharwat kandil mohamed el shobari talaat abd allah amgad fouad mostafa abu zeid ahmed abu el eneen nabil gad el-hak gamal el ebidy omar fathy ahmed sultan mohamed abdel wahab | 2017 | World Journal of Gastroenterology2017，23，38： | 15 |
| 6 | Semi-hot Stamping as an Improved Process of Hot Stamping显示文摘Reducing the forming load,deletion of springback,increasing the formability of sheets as well as producing high strength parts are the main reasons to apply hot stamping process.Hot stamping process and 22MnB5 steels are the state of the art process and grades,respectively;however novel processes and steel grades are under considerations.In the current research,behavior of the steel grade MSW1200 blanks under semi and fully hot stamping processes was characterized.During semi-hot stamping process,the blank was firstly heated to a temperature of about 650℃ and then formed and quenched in the die assembly,simultaneously.Microstructure and mechanical properties of semi and fully hot stamped blanks were studied and the results were compared with those of normally water/air quenched blanks.The hot stamped blanks attained the strength values as high as water quenched blanks.The highest ductility and consequently,the best formability were achieved for the blank which had been semi-hot stamped.It was concluded that for the mentioned steel,semi-hot stamping process could be considered as an improved thermo-mechanical process which not only guaranteed a high formability,but also led to ultra high strength values. | Malek Naderi Mostafa Ketabchi Mahmoud Abbasi Wolfgang Bleck | 2011 | Journal of Materials Science & Technology2011，27，4： | 15 |
| 7 | The wonders of BMP9:From mesenchymal stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism to regenerative medicine显示文摘Although bone morphogenetic proteins(BMPs)initially showed effective induction of ectopic bone growth in muscle,it has since been determined that these proteins,as members of the TGF-b superfamily,play a diverse and critical array of biological roles.These roles include regulating skeletal and bone formation,angiogenesis,and development and homeostasis of multiple organ systems.Disruptions of the members of the TGF-b/BMP superfamily result in severe skeletal and extra-skeletal irregularities,suggesting high therapeutic potential from understanding this family of BMP proteins.Although it was once one of the least characterized BMPs,BMP9 has revealed itself to have the highest osteogenic potential across numerous experiments both in vitro and in vivo,with recent studies suggesting that the exceptional potency of BMP9 may result from unique signaling pathways that differentiate it from other BMPs.The effectiveness of BMP9 in inducing bone formation was recently revealed in promising experiments that demonstrated efficacy in the repair of critical sized cranial defects as well as compatibility with bone-inducing bio-implants,revealing the great translational promise of BMP9.Furthermore,emerging evidence indicates that,besides its osteogenic activity,BMP9 exerts a broad range of biological functions,including stem cell differentiation,angiogenesis,neurogenesis,tumorigenesis,and metabolism.This review aims to summarize our current understanding of BMP9 across biology and the body. | Sami Mostafa Mikhail Pakvasa Elam Coalson Allen Zhu Alex Alverdy Hector Castillo Jiaming Fan Alex Li Yixiao Feng Di Wu Elliott Bishop Scott Du Mia Spezia Alissa Li Ofir Hagag Alison Deng Winny Liu Mingyang Li Sherwin S·Ho Aravind Athiviraham Michael J·Lee Jennifer Moriatis Wolf Guillermo A·Ameer Hue H·Luu Rex C·Haydon Jason Strelzow Kelly Hynes Tong-Chuan He Russell R·Reid | 2019 | Genes & Diseases2019，6，3： | 15 |
| 8 | Enhancing mechanical behaviors of collapsible soil using two biopolymers显示文摘This study aims to investigate the possibility of using biopolymer(environmental friendly material) to enhance the mechanical behaviors of collapsible soil.Two types of biopolymers were(xanthan gum and guar gum) used in this study due to their stable behaviors under severe conditions and their availability with reasonable prices.The experimental program focused on three major soil properties,i.e.compaction characterizations,collapsible potential and shear parameters.These three properties are essential in process of soil improvement.Different biopolymer concentrations were used in this study and the experimental program was performed at two curing periods(soon after mixing the soil with the biopolymer and after one week curing time).Shear parameters were measured for the treated specimens under both soaked and unsoaked conditions,while a collapsible potential test was performed under different mixing conditions(wet mix and dry mix).A numerical model was built to predict the behavior of the treated collapsible soil after and before water immersing.The results indicated that the ability of both xanthan gum and guar gum can be used as improvement materials for collapsible soil treatment.The collapsible potential has been reduced from 9%to 1%after mixing the soil with 2%biopolymer concentration in the wet case.After one week curing,the cohesion has been increased from 8.5 kPa to105 kPa by increasing the xanthan gum concentration from zero to 2%,leading to an overall improvement in soil shear strength.It also proves that the guar gum is superior to the xanthan gum.The shear strength of soil can be increased by about 30%when using the guar gum in comparison with the xanthan gum at the same conditions;however,the collapsible potential of soil material will be reduced by about 20%. | Mohamed Ayeldeen Abdelazim Negm Mostafa El-Sawwaf Masaki Kitazume | 2017 | Journal of Rock Mechanics and Geotechnical Engineering2017，9，2： | 14 |
| 9 | Application of artificial neural networks and multivariate statistics to estimate UCS using textural characteristics显示文摘Before any rock engineering project,mechanical parameters of rocks such as uniaxial compressive strength and young modulus of intact rock get measured using laboratory or in-situ tests,but in some situations preparing the required specimens is impossible.By this time,several models have been established to evaluate UCS and E from rock substantial properties.Artificial neural networks are powerful tools which are employed to establish predictive models and results have shown the priority of this technique compared to classic statistical techniques.In this paper,ANN and multivariate statistical models considering rock textural characteristics have been established to estimate UCS of rock and to validate the responses of the established models,they were compared with laboratory results.For this purpose a data set for 44 samples of sandstone was prepared and for each sample some textural characteristics such as void,mineral content and grain size as well as UCS were determined.To select the best predictors as inputs of the UCS models,this data set was subjected to statistical analyses comprising basic descriptive statistics,bivariate correlation,curve fitting and principal component analyses.Results of such analyses have shown that void,ferroan calcitic cement,argillaceous cement and mica percentage have the most effect on USC.Two predictive models for UCS were developed using these variables by ANN and linear multivariate regression.Results have shown that by using simple textural characteristics such as mineral content,cement type and void,strength of studied sandstone can be estimated with acceptable accuracy.ANN and multivariate statistical UCS models,revealed responses with 0.87 and 0.76 regressions,respectively which proves higher potential of ANN model for predicting UCS compared to classic statistical models. | Amin Manouchehrian Mostafa Sharifzadeh Rasoul Hamidzadeh Moghadam | 2012 | International Journal of Mining Science and Technology2012，22，2： | 13 |
| 10 | Neural EGF-like protein 1(NELL-1):Signaling crosstalk in mesenchymal stem cells and applications in regenerative medicine显示文摘Bone tissue regeneration holds the potential to solve both osteoporosis and large skeletal defects,two problems associated with significant morbidity.The differentiation of mesenchymal stem cells into the osteogenic lineage requires a specific microenvironment and certain osteogenic growth factors.Neural EGF Like-Like molecule 1(NELL-1)is a secreted glycoprotein that has proven,both in vitro and in vivo,to be a potent osteo-inductive factor.Furthermore,it has been shown to repress adipogenic differentiation and inflammation.NELL-1 can work synergistically with other osteogenic factors such as Bone Morphogenic Protein(BMP)2 and9,and has shown promise for use in tissue engineering and as a systemically administered drug for the treatment of osteoporosis.Here we provide a comprehensive up-to-date review on the molecular signaling cascade of NELL-1 in mesenchymal stem cells and potential applications in bone regenerative engineering. | Mikhail Pakvasa Alex Alverdy Sami Mostafa Eric Wang Lucy Fu Alexander Li Leonardo Oliveira Aravind Athiviraham Michael J.Lee Jennifer Moriatis Wolf Tong-Chuan He Guillermo A.Ameer Russell R.Reid | 2017 | Genes & Diseases2017，4，3： | 13 |
| 11 | The potential for liquid biopsies in the precision medical treatment of breast cancer显示文摘Currently the clinical management of breast cancer relies on relatively few prognostic/predictive clinical markers(estrogen receptor, progesterone receptor, HER2), based on primary tumor biology. Circulating biomarkers, such as circulating tumor DNA(ctDNA) or circulating tumor cells(CTCs) may enhance our treatment options by focusing on the very cells that are the direct precursors of distant metastatic disease, and probably inherently different than the primary tumor's biology. To shift the current clinical paradigm, assessing tumor biology in real time by molecularly profiling CTCs or ctDNA may serve to discover therapeutic targets, detect minimal residual disease and predict response to treatment. This review serves to elucidate the detection,characterization, and clinical application of CTCs and ctDNA with the goal of precision treatment of breast cancer. | Victoria A.Forte Dany K.Barrak Mostafa Elhodaky Lily Tung Anson Snow Julie E.Lang | 2016 | Cancer Biology & Medicine2016，13，1： | 13 |
| 12 | Rome Ⅲ:The functional gastrointestinal disorders, third edition, 2006显示文摘Functional gastrointestinal disorders (FGIDs) represent a common and important class of disorders within gastroenterology. RomeⅠ, the first edition was published in 1994, with symptom-based diagnostic criteria for FGIDs. These criteria began to change the diagnostic approach to FGIDs, and no longer considered 'diagnoses of exclusion' but rather 'diagnoses of inclusion'. Rome Ⅱ, the second edition published in 2000, resulted from the continual process of analyzing new scientific and clinical evidence in the study of FGIDs. Rome Ⅱ, diagnostic criteria for irritable bowel syndrome (IBS), was extended with a focus on the frequency of symptoms occurring twelve weeks (not necessarily consecutive weeks) within twelve months. ROME Ⅲ, the third edition, conservative one, was published in September 2006, with changes made only where there is good evidence to do so. Some of the differences between Rome Ⅱ and Rome Ⅲ criteria are highlighted in this issue. | Randa Mostafa | 2008 | World Journal of Gastroenterology2008，14，13： | 13 |
| 13 | Kinematic Analysis and Design of a 3-DOF Translational Parallel Robot显示文摘Parallel mechanisms are widely used in various fields of engineering and industrial applications such as machine tools, flight simulators, earthquake simulators, medical equipment, etc. Parallel mechanisms are restricted to some limitations such as irregular workspace, existence of singular points and complexity of control systems which should be studied and analyzed for effective and efficient use. In this research, a new machine tool with parallel mechanism which has three translational degrees of freedom is studied and the workspace and singular points are determined by deriving analytical equations and then utilizing of Matlab software. To do so, forward and inverse kinematics of the mechanism are obtained and workspace and singular points are calculated using a search algorithm.Afterward, in order to validate the results, the proposed mechanism is simulated in automatic dynamics analysis of mechanical systems(ADAMS) software. Moreover, in order to investigate the quality of robot performance and dexterity of the mechanism in its workspace,global dexterity index(GDI) of the robot is calculated using Jacobean matrix at different positions of the mobile platform. | Mahmood Mazare Mostafa Taghizadeh M. Rasool Najafi | 2017 | International Journal of Automation and computing2017，14，4： | 13 |
| 14 | Video capsule endoscopy:Perspectives of a revolutionary technique显示文摘Video capsule endoscopy(VCE)was launched in 2000and has revolutionized direct endoscopic imaging of the gut.VCE is now a first-line procedure for exploring the small bowel in cases of obscure digestive bleeding and is also indicated in some patients with Crohn’s disease,celiac disease,and polyposis syndrome.A video capsule has also been designed for visualizing the esophagus in order to detect Barrett’s esophagus or esophageal varices.Different capsules are now available and differ with regard to dimensions,image acquisition rate,battery life,field of view,and possible optical enhancements.More recently,the use of VCE has been extended to exploring the colon.Within the last 5 years,tremendous developments have been made toward increasing the capabilities of the colon capsule.Although colon capsule cannot be proposed as a first-line colorectal cancer screening procedure,colon capsule may be used in patients with incomplete colonoscopy or in patients who are unwilling to undergo colonoscopy.In the near future,new technological developments will improve the diagnostic yield of VCE and broaden its therapeutic capabilities. | Simon Bouchard Mostafa Ibrahim Andre Van Gossum | 2014 | World Journal of Gastroenterology2014，20，46： | 12 |
| 15 | Management of tear trough deformity with and without tear trough-orbicularis retaining ligament complex release in transconjunctival blepharoplasty: a comparative study显示文摘AIM: To evaluate the effect of releasing the orbicularis retaining ligament(ORL) complex of the tear trough combined with the transconjunctival blepharoplasty in the surgical management of tear trough deformity compared with the effect of blepharoplasty alone. METHODS: A prospective, randomized(by closed envelope technique), controlled surgical trial which included 50 patients(100 eyes) with bilateral visible tear trough deformity and lower eyelid fat bulging, was divided into two groups where 25 patients(50 eyes) had tear trough-ORL release with blepharoplasty and 25 patients(50 eyes) didn't. Qualitative and quantitative assessments of tear trough deformity were done at 6 mo postoperatively, achieving grade 0 or 1 of Barton's classification was considered a success. Standardized photographic documentation of each patient was done pre and postoperatively, also assessment of the patients' satisfaction postoperatively was done and ranked as excellent, very good, good or fair. RESULTS: There was statistically significant difference between the two groups in the overall aesthetic results postoperatively regarding the qualitative and quantitative analysis of the tear trough deformity, where patients who had tear trough-ORL complex release had more successful outcomes than those of the second group. CONCLUSION: ORL release should be done in patients with tear trough deformity in order to release the tethering effect of this ligament which causes the prominence of the naso jugal groove. | Tamer Ismail Gawdat Engy Abd Eltawab Elsherif Yomna Amr Alahmadawy Yehia Salah Eldin Mostafa | 2019 | International Journal of Ophthalmology(English edition)2019，12，1： | 12 |
| 16 | 开鲁盆地砂岩型铀矿中黄铁矿与铀矿化成因关系探讨显示文摘开鲁盆地位于松辽盆地西南部,是中国北方砂岩型铀矿勘查的重点地区,自钱家店铀矿床发现以来,盆地内上白垩统姚家组目的层中相继发现了一些具有工业价值的铀矿床。为查明该层位中黄铁矿成因及其形成机制,探讨其与铀矿化之间的关系,本研究对含矿层砂岩中黄铁矿与铀矿物矿物学特征、黄铁矿S同位素开展细致研究。研究表明:(1)开鲁盆地姚家组砂岩中铀主要以独立铀矿物及吸附铀形式存在,独立铀矿物以沥青铀矿为主,含少量的钛铀矿及部分铀石,多数沿黄铁矿周边生长。吸附态的铀与黏土矿物密切相关。(2)姚家组砂岩中黄铁矿主要以草莓状、胶状及粒状产出,多与沥青铀矿共生,其中黄铁矿S同位素(d^(34)S=–55.6‰~23.2‰),平均值–20.87‰,变化范围很大,说明硫的分馏程度较高,硫的来源范围较广。(3)分析表明黄铁矿具有细菌硫酸盐还原作用及热化学硫酸盐还原作用两种成因,并探讨了这2种成因黄铁矿的形成机制。综合前人研究,结合研究区成矿地质背景,认为黄铁矿为铀成矿作用提供了发生还原反应所需要的还原剂,且黄铁矿及铀矿物的形成与区内热流体存在紧密联系。 | 陈梦雅 聂逢君 Mostafa FAYEK | 2021 | 地球学报2021，42，6： | 12 |
| 17 | 西准白杨河铍矿床萤石及流体包裹体特征显示文摘利用激光测温学和激光拉曼光谱方法,通过镜下观察,研究了白杨河铍矿床与铍成矿作用有关的脉石矿物(萤石),将萤石分为4 个期次,其中第三期萤石与铍成矿关系最密切.萤石流体包裹体具低盐(0.7%-7.0%)、低温(89.7℃-188.9℃)的特征,第三期萤石脉流体包裹体成矿温度99.4℃-120.5℃,成矿盐度3.5%-5.4%,与铍矿物属同-期,揭示出该矿床成矿流体为低温、低盐度热液. | 杨文龙 Mostafa Fayek 李彦龙 王谋 周剑 | 2014 | 新疆地质2014，32，1： | 11 |
| 18 | Development of underground mine monitoring and communication system integrated ZigBee and GIS显示文摘An automated underground mine monitoring and communication system based on the integration of new technologies is introduced to promote safety and health,operational management and cost-effectiveness.The proposed system integration considering Wireless Sensor Network(WSN) assisted Geographic Information System(GIS) enables to monitor and control underground mining applications from surface office.Based on the capabilities of WSNs,ZigBee network is adapted for near real-time monitoring,ventilation system control and emergency communication in underground mine.ZigBee nodes were developed to sense environmental attributes such as temperature,humidity and gases concentration;switching ON and OFF ventilation fans;and texting emergency messages.A trigger action plan for monitored attributes above normal and threshold value limits is programmed in the surface GIS management server.It is designed to turn the auxiliary fans on remotely or automatically in orange condition and sending evacuation messages for underground miners in unsafe(red) condition.Multi-users operation and 3D visualisations are other successful achievements of the proposed system for the underground monitoring and communication. | Moridi Mohammad Ali Kawamura Youhei Sharifzadeh Mostafa Chanda Emmanuel Knox Wagner Markus Jang Hyongdoo Okawa Hirokazu | 2015 | International Journal of Mining Science and Technology2015，25，5： | 11 |
| 19 | Ultrafast hydrogen bond dynamics of liquid water revealed by terahertz-induced transient birefringence显示文摘The fundamental properties of water molecules,such as their molecular polarizability,have not yet been clarified.The hydrogen bond network is generally considered to play an important role in the thermodynamic properties of water.The terahertz(THz)Kerr effect technique,as a novel tool,is expected to be useful in exploring the low-frequency molecular dynamics of liquid water.Here,we use an intense and ultrabroadband THz pulse(peak electric field strength of 14.9 MV/cm,centre frequency of 3.9 THz,and bandwidth of 1–10 THz)to resonantly excite intermolecular modes of liquid water.Bipolar THz field-induced transient birefringence signals are observed in a free-flowing water film.We propose a hydrogen bond harmonic oscillator model associated with the dielectric susceptibility and combine it with the Lorentz dynamic equation to investigate the intermolecular structure and dynamics of liquid water.We mainly decompose the bipolar signals into a positive signal caused by hydrogen bond stretching vibration and a negative signal caused by hydrogen bond bending vibration,indicating that the polarizability perturbation of water presents competing contributions under bending and stretching conditions.A Kerr coefficient equation related to the intermolecular modes of water is established.The ultrafast intermolecular hydrogen bond dynamics of water revealed by an ultrabroadband THz pump pulse can provide further insights into the transient structure of liquid water corresponding to the pertinent modes. | Hang Zhao Yong Tan Liangliang Zhang Rui Zhang Mostafa Shalaby Cunlin Zhang Yuejin Zhao Xi-Cheng Zhang | 2020 | Light(Science & Applications)2020，9，1： | 10 |
| 20 | 3-D bioprinting technologies in tissue engineering and regenerative medicine:Current and future trends显示文摘Advances in three-dimensional(3D)printing have increased feasibility towards the synthesis of living tissues.Known as 3D bioprinting,this technology involves the precise layering of cells,biologic scaffolds,and growth factors with the goal of creating bioidentical tissue for a variety of uses.Early successes have demonstrated distinct advantages over conventional tissue engineering strategies.Not surprisingly,there are current challenges to address before 3D bioprinting becomes clinically relevant.Here we provide an overview of 3D bioprinting technology and discuss key advances,clinical applications,and current limitations.While 3D bioprinting is a relatively novel tissue engineering strategy,it holds great potential to play a key role in personalized medicine. | Elliot S.Bishop Sami Mostafa Mikhail Pakvasa Hue H.Luu Michael J.Lee Jennifer Moriatis Wolf Guillermo A.Ameer Tong-Chuan He Russell R.Reid | 2017 | Genes & Diseases2017，4，4： | 10 |
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