|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Advances in prognostic factors in acute pancreatitis:a mini-review显示文摘BACKGROUND:Early assessment of the severity of acute pancreatitis is essential to the proper management of the disease.It is dependent on the criteria of the Atlanta classification system.DATA SOURCES:PubMed search of recent relevant articles was performed to identify information about the severity and prognosis of acute pancreatitis.RESULTS:The scoring systems included the Ranson's or Glasgow's criteria ≥3,the APACHE II classification system ≥8,and the Balthazar's criteria ≥4 according to the computed tomography enhanced scanning findings.The single factors on admission included age >65 years,obesity,hemoconcentration(>44%),abnormal chest X-ray,creatinine >2 mg/dl,C-reactive protein>150 mg/dl,procalcitonin >1.8 ng/ml,albumin <2.5 mg/dl,calcium <8.5 mg/dl,early hyperglycemia,increased intra-abdominal pressure,macrophage migration inhibitory factor,or a combination of IL-10 >50 pg/ml with calcium <6.6 mg/dl.CONCLUSION:The prediction of the severity of acute pancreatitis is largely based on well defined multiple factor scoring systems as well as several single risk factors. | Theodoros E Pavlidis Efstathios T Pavlidis Athanasios K Sakantamis | 2010 | Hepatobiliary & Pancreatic Diseases International2010，9，5： | 25 |
| 2 | Current opinion on lymphadenectomy in pancreatic cancer surgery显示文摘BACKGROUND:Adenocarcinoma of the pancreas exhibits aggressive behavior in growth,inducing an extremely poor prognosis with an overall median 5-year survival rate of only 1%-4%.Curative resection is the only potential therapeutic opportunity. DATA SOURCES:A PubMed search of relevant articles published up to 2009 was performed to identify information about the value of lymphadenectomy and its extent in curative resection of pancreatic adenocarcinoma. RESULTS:Despite recent advances in chemotherapy,radio-therapy or even immunotherapy,surgery still remains the major factor that affects the outcome.The initial promising performance in Japan gave conflicting results in Western countries for the extended and more radical pancreatectomy; it has failed to prove beneficial.Four prospective,randomized trials on extended versus standard lymphadenectomy during pancreatic cancer surgery have shown no improvement in long-term survival by the extended resection.The exact lymph node status,including malignant spread and the total number retrieved as well as the lymph node ratio,is the most important prognostic factor.Positive lymph nodes after pancreatectomy are present in 70%.Paraaortic lymph node spread indicates poor prognosis. CONCLUSIONS:Undoubtedly,a standard lymphadenectomy including>15 lymph nodes must be no longer preferred in patients with the usual head location.The extended lymphadenectomy does not have any place,unless in randomized trials.In cases with body or tail location,the radical antegrade modular pancreatosplenectomy gives promising results.Nevertheless,accurate localization and detailed examination of the resected specimen are required for better staging. | Theodoros E Pavlidis Efstathios T Pavlidis Athanasios K Sakantamis | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，1： | 12 |
| 3 | Autoimmune pancreatitis versus pancreaticcancer: a comprehensive review withemphasis on differential diagnosis显示文摘BACKGROUND: Autoimmune pancreatitis (AIP) is a rare form of chronic pancreatitis with a discrete pathophysiology occasional diagnostic radiological findings, and characteristic histological features. Its etiology and pathogenesis are still under investigation, especially during the last decade Another aspect of interest is the attempt to establish specific criteria for the differential diagnosis between autoimmune pancreatitis and pancreatic cancer, entities that are frequently indistinguishable. DATA SOURCES: An extensive search of the PubMed database was performed with emphasis on articles about the differential diagnosis between autoimmune pancreatitis and pancreatic cancer up to the present. RESULTS: The most interesting outcome of recent research is the theory that autoimmune pancreatitis and its various extra-pancreatic manifestations represent a systemic fibro inflammatory process called IgG4-related systemic disease The diagnostic criteria proposed by the Japanese Pancreatic Society, the more expanded HISORt criteria, the new definitions of histological types, and the new guidelines of the International Association of Pancreatology help to establish the diagnosis of the disease types. CONCLUSION: The valuable help of the proposed criteria for the differential diagnosis between autoimmune pancreatitis and pancreatic cancer may lead to avoidance of pointless surgical treatments and increased patient morbidity. | Kyriakos Psarras Minas E Baltatzis Efstathios T Pavlidis Miltiadis A Lalountas Theodoros E Pavlidis Athanasios K Sakantamis | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，5： | 9 |
| 4 | Current surgical management of pancreatic endocrine tumor liver metastases显示文摘BACKGROUND: The management of metastatic disease in pancreatic endocrine tumors (PETs) demands a multidisciplinary approach and the cooperation of several medical specialties. The role of surgery is critical, even when a radical excision cannot always be achieved. DATA SOURCES: A PubMed search of relevant articles published up to February 2011 was performed to identify current information about PET liver metastases regarding diagnosis and management, with an emphasis on surgery. RESULTS: The early diagnosis of metastases and their accurate localization, most commonly in the liver, is very important. Surgical options include radical excision, and palliative excision to relieve symptoms in case of failure of medical treatment. The goal of the radical excision is to remove the primary tumor bulk and all liver metastases at the same time, but unfortunately it is not feasible in most cases. Palliative excisions include aggressive tumor debulking surgeries in well-differentiated carcinomas, trying to remove at least 90% of the tumor mass, combined with other additional destructive techniques such as hepatic artery embolization or chemoembolization to treat metastases or chemoembolization to relieve symptoms in cases of rapidly growing tumors. The combination of chemoembolization and systemic chemotherapy results in better response and survival rates. Other local destructive techniques include ethanol injection, cryotherapy and radiofrequency ablation. CONCLUSION: It seems that the current management of PETs can achieve important improvements, even in advanced cases. | Theodoros E Pavlidis Kyriakos Psarras Nikolaos G Symeonidis Efstathios T Pavlidis Athanasios K Sakantamis | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，3： | 5 |
| 5 | Use of isolated Roux loop for pancreaticojejunostomy reconstruction after pancreaticoduodenectomy显示文摘AIM: To evaluate the efficacy of the isolated Roux loop technique in decreasing the frequency of pancreaticojejunal anastomosis failure. METHODS: We retrospectively reviewed 88 consecutive patients who underwent pancreaticoduodenectomy (standard or pylorus-preserving). Single jejunal loop was used in 42 patients (SL group) while isolated Roux loop was used in 46 patients (RL group). Demographic characteristics (age, gender) and perioperative results (major/minor complications, mortality, hospital stay) were compared between the two groups. RESULTS: Mortality was almost equal in both groups and overall mortality was 2.27%. Leak rate from the pancreaticojejunal anastomosis and hospital stay were lower in the RL group without significant difference. Morbidity was 39.1% in the RL group, insignificantly higherthan the SL group. Operative time was almost 30 min longer in the RL group. CONCLUSION: The isolated Roux loop, although an equally safe alternative, does not present advantages over the traditional use of a single jejunal loop. Randomized controlled studies are required to further clarify its efficacy. | Konstantinos Ballas Nikolaos Symeonidis Savvas Rafailidis Theodoros Pavlidis Georgios Marakis Nikolaos Mavroudis Athanasios Sakantamis | 2010 | World Journal of Gastroenterology2010，16，25： | 4 |
| 6 | Advances in prognostic factors in acute pancreatitis: a mini-review 显示文摘 | Pavlidis TE Pavlidis ET Sakantamis AK | 2010 | Hepatohiliary Pancreat Dis Int2010，9，48： | 1 |
| 7 | Advances in prognostic factors in acute panereatltis: a minireview 显示文摘 | Pavlidis TE Pavlidis ET Sakantamis AK | 2010 | Hepatobiliary Pancreat Dis Int2010，9，2： | 1 |
| 8 | Advances in prognostic factors in acute pancreatitis: a mini-review 显示文摘 | Pavlidis TE Pavlidis ET Sakantamis AK | 2010 | Hepatobiliary Pancreat Dis Int2010，9，5： | 1 |
| 9 | The Effect of Celecoxib Administration on the Healing and Neovascularization of Colonic Anastomosis in Rats显示文摘 | Nikolaos Symeonidis Eleni Papakonstantinou Kyriakos Psarras Konstantinos Ballas Theodoros Pavlidis Georgios Karakiulakis Athanasios Sakantamis | 2014 | Journal of Investigative Surgery2014，，3： | 1 |
| 10 | The effect of bevacizumab on colon anastomotic healing in rats显示文摘 | Efstathios T. Pavlidis Konstantinos D. Ballas Nikolaos G. Symeonidis Kyriakos Psarras Georgios Koliakos Kokona Kouzi-Koliakos Konstantina Topouridou Savas F. Rafailidis Theodoros E. Pavlidis Georgios N. Marakis Athanasios K. Sakantamis | 2010 | International Journal of Colorectal Disease2010，，12： | 1 |
| 11 | CmTent opinion on lymphadenectomy in pancreatic cancer surgery 显示文摘 | PAVLIDIS TE PAVLIDIS ET SAKANTAMIS AK | 2011 | Hepatobiliary Pancreat Dis Int2011，10，1： | 1 |
| 12 | Combination docetaxel (Taxotere), fluorouracil, and leucovorin (TFL), as first-line chemotherapy in advanced gastric cancer: a Hellenic Cooperative Oncology Group phase II study显示文摘 | Pavlos Papakostas Dimitrios Tsavdaridis Paris Kosmidis Haralabos P. Kalofonos Athanassios Sakantamis Dimitrios Janinis Dimosthenis Skarlos Dimitrios Bafaloukos Aristotelis Bamias Nikos Xiros George Fountzilas | 2006 | Gastric Cancer2006，，1： | 1 |
| 13 | The role of laparoendoscopic surgery in acute pancreatitis显示文摘 | Pavlidis TE Pavlidis ET Sakantamis AK | 2011 | Surg Endosc2011，25，7： | 1 |
| 14 | The role of laparoscopic surgery in gastric cancer显示文摘 | Pavlidis TE Pavlidis ET Sakantamis AK | | 0，，2： | 1 |
| 15 | The role of laparoendo- scopic surgery in acute pancreatitis 显示文摘 | Pavlidis TE Pavlidis ET Sakantamis A K | 2011 | Surg Endosc2011，25，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员