维普中文期刊产品整合服务
16278篇 您的检索式:作者名="TE"
    题名 作者 年代 出处 被引量
1ACCF/SCAI/SVMB/SIR/ASITN 2007年颈动脉支架置入术临床专家共识文件——美国心脏病学会基金会特别工作组关于临床专家共识文件的报告(ACCF/SCAI/SVMB/SIR/ASITN颈动脉支架置入术临床专家共识文件委员会):与美国介入与治疗神经放射学学会、心血管造影和介入治疗学会、血管医学和生物学学会、介入放射学学会联合发布显示文摘序言 本文件在美国心血管造影和介入治疗学会(Society for Cardiovascular Angiography and Interventions,SCAI)、血管医学和生物学学会(Society for Vascular Medicine and Biology,SVMB)、介入放射学学会(Society of Interventional Radiology,SIR)、美国介入与治疗神经放射学学会(American Society of Interventional & Therapeutic Neuroradiology,ASITN)共同倡导下,Bates ER Babb JD Casey DE Jr Cates CU Duckwiler GR Feldman TE Gray WA Ouriel K Peterson ED Rosenfield K Rundback JH Safian RD Sloan MA White CJ 刘慧慧(译) 吴延华(译) 靳勇(译) 曹勇军(译) 刘春风(译) 2007国际脑血管病杂志2007,15,5:52
2Fairness-Oriented Hybrid Precoding for Massive MIMO Maritime Downlink Systems with Large-Scale CSIT显示文摘Different from conventional cellular networks, a maritime communication base station(BS) has to cover a much wider area due to the limitation of available BS sites. Accordingly the performance of users far away from the BS is poor in general. This renders the fairness among users a challenging issue for maritime communications. In this paper, we consider a practical massive MIMO maritime BS with hybrid digital and analog precoding. Only the large-scale channel state information at the transmitter(CSIT) is considered so as to reduce the implementation complexity and overhead of the system. On this basis, we address the problem of fairness-oriented precoding design. A max-min optimization problem is formulated and solved in an iterative way. Simulation results demonstrate that the proposed scheme performs much better than conventional hybrid precoding algorithms in terms of minimum achievable rate of all the users, for the typical three-ray maritime channel model.Chengxiao Liu Wei Feng Te Wei Ning Ge 2018China Communications2018,15,1:23
3Cancer stem-like cells can be isolated with drug selection in human ovarian cancer cell line SKOV3显示文摘为药抵抗的肿瘤的发展的一个新兴的模型利用作为癌症干细胞(CSC ) 或开始癌症的房间(用户信息控制系统) 知道的自我更新的恶意的祖先的一个水池。这研究的目的是从卵巢的癌症房间线 SKOV3 宣传如此的用户信息控制系统。SKOV3 范围房间在与表皮的生长因素补充的没有浆液的文化系统用 40.0 mol/l cisplatin 和 10.0 mol/l paclitaxel 被选择,基本成纤维细胞生长因素,白血病禁止的因素或标准包含浆液的系统。这些房间在药选择(cisplatin 和 paclitaxel ) 和没有浆液的文化系统下面形成了非支持者范围。选择范围房间对 cisplatin, paclitaxel, adriamycin,和 methotrexate 更抵抗。重要地,范围房间有自强的性质,与干细胞基因 Nanog, Oct4, sox2, nestin, ABCG2, CD133,和干细胞因素受体的高表示 CD117 (c 工具包) 。一致地,流动 cytometric 分析表明范围房间比区分的房间(33%) 有 CD133+/CD117+-positive 房间(71%) 的一个高得多的百分比。而且, SKOV3 范围房间是更多的 tumorigenic。而且, cDNA microarray 和随后的本体论的分析表明分类基因的一个大比例与 angiogenesis,细胞外的矩阵,调停 integrin 的发信号小径,房间粘附,和房间增长有关。从在这个文化系统下面的 SKOV3 房间线的 subpopulation 隔离出现一在为以他们的幸存,自强,和 chemoresistance 学习卵巢的 CSC,并且为开发明确地防碍卵巢的 CSC 的治疗学的药的 vitro 模型合适。Li Ma Dongmei Lai Te Liu Weiwei Cheng Lihe Guo 2010Acta Biochimica et Biophysica Sinica2010,42,9:18
4Development of Transgenic Glyphosate-Resistant Rice with G6 Gene Encoding 5-Enolpyruvylshikimate-3-Phosphate Synthase显示文摘Glyphosate-resistant crops have been a huge economic success for genetic engineering. The creating of new glyphosate-resistant plants would increase the available choices for planting and lower the price of genetically modified crop seeds. A novel G6 gene from Pseudomonas putida that encoded 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS) was previously isolated. The G6 gene was transfected into rice via Agrobacterium-mediated transformation. The transgenic rice obtained was confirmed by PCR, Southern, and Western blots. The lab experiment and field trials further confirmed that the transgenic rice can survive glyphosate spraying at a dose of 8 g L-1. In contrast, conventional rice was killed at a weed control glyphosate spray dose of 1 g L-1. Altogether, the present study showed that the G6 gene works well in rice in vivo for glyphosate-resistance.ZHAO Te LIN Chao-yang SHEN Zhi-cheng 2011Agricultural Sciences in China2011,10,9:17
5Prognostic significance of neutrophil to lymphocyte ratio in pancreatic cancer: A meta-analysis显示文摘AIM:To conduct a meta-analysis evaluating theassociation between the peripheral blood neutrophil to lymphocyte ratio(NLR) and the outcome of patients with pancreatic cancer.METHODS:Studies evaluating the relationship between the peripheral blood NLR and outcome of patients with pancreatic cancer published up to May 2014 were searched using electronic databases, including Pub Med, Web of Science, Embase and Ovid.A meta-analysis was performed to pool the hazard ratios(HRs) or odds ratios(ORs) and their 95% confidence intervals(CIs) using either a fixed-effects model or a random-effects model to quantitatively assess the prognostic value of NLR and its association with clinicopathological parameters.RESULTS:Eleven studies containing a total of 1804 patients were eligible according to our selection criteria, and combined hazard ratios indicated that high NLR was a poor prognostic marker for pancreatic cancer patients because it had an unfavorable impact on the overall survival(OS)(HR =2.61, 95%CI:1.68-4.06, P =0.000) and cancer specific survival(HR =1.66, 95%CI:1.08-2.57, P =0.021).Subgroup analysis revealed that high NLR was associated with poor OS in patients with mixed treatment(HR =4.36, 95%CI:2.50-7.61, P =0.000), chemotherapy(HR =2.08, 95%CI:1.49-2.9, P =0.000), or surgical resection(HR =1.2, 95%CI:1.00-1.44, P =0.048).Additionally, high NLR was significantly correlated with tumor metastasis(OR =1.69, 95%CI:1.10-2.59, P =0.016), poor tumor differentiation(OR =2.75, 95%CI:1.19-6.36, P =0.016), poor performance status(OR =2.56, 95%CI:1.63-4.03, P =0.000), high cancer antigen 199(OR =2.62, 95%CI:1.49-4.60, P =0.000), high C-reactive protein(OR =4.32, 95%CI:2.71-6.87, P =0.000), and low albumin(OR =3.56, 95%CI:1.37-9.27, P =0.009).CONCLUSION:High peripheral blood NLR suggested a poor prognosis for patients with pancreatic cancer,and it could be a novel marker of survival evaluation and could help clinicians develop therapeutic strategies for pancreatic cancer patients.Jian-Jun Yang Zhi-Gao Hu Wu-Xiang Shi Te Deng Song-Qing He Sheng-Guang Yuan 2015World Journal of Gastroenterology2015,21,9:15
6SWMM-based methodology for block-scale LID-BMPs planning based on site-scale multi-objective optimization: a case study in Tianjin显示文摘最好的管理惯例(LID-BMPs ) 的低影响发展类型试图减轻城市的 stormwater 流量并且以一个节俭、 eco 友好的方法减少污染物质负担并且在现代城市的 stormwater 管理成为了一颗全球担心。新方法论基于为块规模 LID-BMPs 计划的 stormwater 管理模型(SWMM ) 被开发。在地点规模的综合 LID-BMP 链布局优化在全部块规模与情形分析打包的这个方法城市的区域。非统治的排序的基因算法(NSGA-II ) 成功地通过大蟒被联合到 SWMM 完成地点规模优化过程。研究区域的不同的盖情形根据优化 LID-BMP 链布局被设计。认为流量是数量索引,污染物质负担,和构造费用的多索引评估同时帮助了作为计划计划的期末考试选择划算的情形。在天津的案例研究,中国,被进行表明建议方法论。结果显示出全部的流量体积, 22%-46% 山峰流动减小效率,和超过 32% 污染物质移动率的那超过 75% 控制率被完成。坚韧性分析显示选择最后的计划计划与改变的重量价值是更加柔韧的。Te Xu Haifeng Jia Zheng Wang Xuhui Mao Changqing Xu 2017Frontiers of Environmental Science & Engineering2017,11,4:13
7Evolution of laparoscopy in colorectal surgery:An evidencebased review显示文摘Open surgery for colorectal disease has progressed significantly over the past century from humble beginnings to form the mainstay of treatment for colorectal cancer and a number of benign conditions.Following the introduction of laparoscopic abdominal surgery,the next stage in the evolution of the specialty began in the 1990s with the first laparoscopic colonic resection.Following some early concerns regarding its safety and oncological efficacy during the latter part of that decade,laparoscopic colorectal surgery rapidly came into mainstream use in the early part of the current century with evidence supporting its use being made available from large scale randomised controlled trials.This article provides an evidence-based summary of this evolutionary process as it relates to both benign and malignant colorectal disease,as well as discussion of the next phase of new technologies such as robotic surgery.Alexander Emmanuel Blackmore Mark Te Ching Wong Choong Leong Tang 2014World Journal of Gastroenterology2014,20,17:12
8Cyclooxygenase-2 polymorphisms and the risk of esophageal adeno-or squamous cell carcinoma显示文摘AIM:To determine whether-1195 A→G and/or-765 G→C polymorphisms in Cyclooxygenase-2(COX-2 ) may have a risk modifying effect on the development of esophageal carcinoma in a Dutch Caucasian population.METHODS:Two study groups were recruited, 252 patients with esophageal carcinoma and 240 healthy controls, matched for race, age, gender and recruiting area.DNA was isolated from whole blood and used for genotyping.PCR products were digested with restriction enzymes and products were analyzed by agarose gel electrophoresis.Odds ratios(OR) and 95% confldence intervals(CI) were estimated.RESULTS:The distribution of the-1195 A→G polymorphism was signif icantly different in esophageal cancer patients compared to controls.The-1195 GG genotype resulted in a higher risk of developing esophageal adenocarcinoma(OR = 3.85, 95% CI:1.45-10.3) compared with the-1195 AA genotype as a reference.The-765 G→C genotype distribution was not different between the two groups.The GG/ GG haplotype was present more often in esophageal adenocarcinoma patients than in controls(OR = 3.45, 95% CI:1.24-9.58;with AG/AG as a reference).The same trends were observed in patients with squamous cell carcinomas, however, the results did not reach statistical signif icance.CONCLUSION:Presence of the COX-2-1195 GG genotype and of the GG/GG haplotype may result in a higher risk of developing esophageal carcinoma.Jón O Kristinsson Paul van Westerveld Rene HM te Morsche Hennie MJ Roelofs T Wobbes Ben JM Witteman Adriaan CITL Tan Martijn GH van Oijen Jan BMJ Jansen Wilbert HM Peters 2009World Journal of Gastroenterology2009,15,28:11
9干扰素调节因子5通过损伤胞葬作用控制动脉粥样硬化病变中的坏死核心形成显示文摘髓系细胞是动脉粥样硬化病变发展和易损斑块形成的核心。动脉吞噬细胞吸收凋亡细胞(胞葬作用)的能力受损,可促进病变生长并建立坏死核心。干扰素调节因子(interferon regulatory factor,IRF)5是髓系细胞功能的重要调节因子。该研究试图确定IRF5是否影响动脉粥样硬化病变的形成和表型。方法:通过两种互补模型,研究IRF5在动脉粥样硬化中的作用:Seneviratne AN Edsfeldt AO Cole JE Kassiteridi C Swart M Park I Green P Khoyratty TE Saliba DG Goddard ME Sansom SN Goncalves I Krams R Udalova IA Monaco C 刘莉 叶鹏 2017中华高血压杂志2017,25,8:9
10影响伤口愈合的因素显示文摘伤口愈合是现代外科学的一个重要组成部分。本文介绍了多种因素对愈合过程的影响。这些因素既可影响伤口本身,又可影响年老、体弱者手术后伤口的愈合能力。本文详尽讨论了感染,它对愈合产生最严重的不良作用。本文还讨论了预防问题。作为外科医生,应尽量了解影响伤口愈合的因素及其机理和临床后果,以减少这些因素的作用,使伤口确实得到愈合。Bucknall TE 刘建民 1990国外医学(创伤与外科基本问题分册)1990,11,3:8
11Effect of atorvastatin on expression of TLR4 and NF-κB p65 in atherosclerotic rabbits显示文摘Objective:To study the effect of atorvastatin on atherosclerotic rabbits.Methods:A total of 60 Now Zealand male rabbits were randomly divided into the normal group,model group and atorvastatin group.The replication rabbit atherosclerotic model with immune injury combined with a high fat diet feeding was used.All rabbits were sacrificed after 3 months.TLR4 and NF-κB p65 were observed by HE staining,immunohistochemistry and western blotting.Results: The expression of TLR4,NF- k B p65 were significantly increased in the model group compared widi the normal group.The expression of TI.R4 and NK- k B p65 decreased significantly in the atorvastatin group,and there was no difference compared with the normal group.Conclusions: The effect of atorvastatin on adierosclerosis may be achieved by the inhibition of the expression of TLK4 and NF-κB p65.Ding-Zhu Shen San-Li Xin Chuan Chen Te Liu 2013Asian Pacific Journal of Tropical Medicine2013,6,6:8
12Does urodynamics predict voiding after benign prostatic hyperplasia surgery in patients with detrusor underactivity?显示文摘Objective:We sought to determine if urodynamic study(UDS)predicted voiding outcomes in men with detrusor underactivity(DU)and benign prostatic enlargement(BPE)who underwent photovaporization of the prostate(PVP).Methods:Between September 2010 and July 2015,106 male patients with BPE and DU were identified.All patients underwent PVP.Urinary retention was noted by the preoperative necessity for an indwelling or intermittent catheter.Data collection included comorbidities,quality of life(QoL)scores,prostate volume,prostate-specific antigen(PSA),UDS and perioperative outcomes.UDS parameters included volume at first desire to void,volume at first urge to void,volume of severe urge,volume at capacity,compliance,detrusor contractions,maximum urinary flow rate(Qmax),and postvoid residual(PVR).Results:A total of 106 men were included in this analysis,who had urinary retention with a Foley catheter or clean intermittent catheterization(CIC)at the time of surgery.At baseline we found patients who voided had a detrusor pressure at Qmax(Pdet@Qmax)of 10.05±6.45 cmH2O compared to 16.78±12.17 cmH2O in those who did not void(p=0.071).Postoperatively,96(90.6%,mean age 76.9±26.2 years)of patients voided successfully while 10(9.4%,mean age 80.52±9.61 years)of patients remained in urinary retention.Mean baseline Qmax was 4.895±5.452 mL/s and 2.900±3.356 mL/s(p=0.087)in those who voided and did not respectively.PVR was 319.23±330.62 mL in those who voided and 276.88263.27 mL(p=0.344)in those who did not void.No UDS parameter predicted who would void postoperatively or improvements in QoL.Conclusions:The patients with DU and BPE might be able to successfully void after undergoing PVP regardless of UDS findings.All men who voided had improved international prostate symptom score and QoL scores compared to baseline and these parameters were durable up to 12 months.Dominique Thomas Kevin C.Zorn Nadir Zaidi Stephanie Ashley Chen Yiye Zhang Alexis Te Bilal Chughtai 2019Asian Journal of Urology2019,6,3:8
13电镀镍新工艺的研究显示文摘研究了在甲酸盐稀溶液中镍的电沉积过程。实验表明,该镀液具有较高的阴极极限电流密度(在pH=2时,能达到70A/dm2)。在该溶液中得到的镀层具有较高的耐蚀性能和硬度及较低的内应力。通过对传质过程的分析,阐明了析氢的副反应可以引起“迁移电流的强化”这种特殊效应。魏杰 苏荣军 周定 ЦупакTE 1998哈尔滨工业大学学报1998,30,4:8
14Differentiation of illicit drugs with THz time-domain spectroscopy显示文摘The terahertz time-domain spectroscopy(THz-TDS) was used for sensing and identifying illicit drugs.The absorption spectra of seven illicit drug samples(morphine and its hydrochloride,cocaine hydrochloride,codeine phosphate,papaverine hydrochloride,pethidine hydrochloride,and thebaine) were studied by THz-TDS at 0.3-2.0 THz at room temperature.The geometric structure and vibration frequencies of morphine were calculated by density functional theory.The four absorption features were dominated by intra-/inter-molecular collective or lattice vibration modes.Each illicit drug has a distinct signature in its THz spectra.The results indicate that the THz-TDS can be used to identify and discriminate illicit drugs by their characteristic fingerprints.LIU Guifeng MA Shihua JI Te ZHAO Hongwei WANG Wenfeng 2010Nuclear Science and Techniques2010,21,4:7
15Pollen wall pattern in Arabidopsis显示文摘The pollen wall is a solid and variously sculptured structure. This pattern is determined inside a tetrad. During meiosis, the callose wall is formed outside of the meiocyte/microspore to form a tetrad. Then, primexine is deposited between the callose wall and the microspore plasma membrane which will become undulated. The sporopollenin deposits on top of the undulated membrane and develops into the pollen wall pattern, while the callose wall is gradually degraded. In recent years, much progress has been made in the study of pollen wall pattern formation, at both molecular and genetic levels. In this review,we summarize these achievements mainly in Arabidopsis.Te Xu Cheng Zhang Que Zhou Zhong-Nan Yang 2016Science Bulletin2016,61,11:7
16COX-2 polymorphisms-765G→C and-1195A→G and colorectal cancer risk显示文摘AIM:To determine the possible modulating effect of the COX-2 polymorphisms,-765G→C and-1195A→G, on the risk of colorectal cancer(CRC)in a Dutch population. METHODS:This case-control study includes 326 patients with CRC and 369 age-and gender-matched controls.Genotypes of the COX-2 polymorphisms -765G→C and-1195A→G were determined by polymerase chain reaction-based restriction fragment length polymorphism.COX-2 genotypes and haplotypes were analyzed and odds ratios with 95%confi- dence intervals were estimated by logistic regression. RESULTS:The-765GG genotype was associated with an increased risk of developing CRC(OR,1.45; 95%CI,1.03-2.04).No significant difference was observed in the genotype distribution of the-1195A→ G polymorphism between patients and controls.The GG/AC haplotype was present significantly less often in patients than in controls(OR 0.44;95%CI,0.22-0.85). When the AC,AG and GG haplotypes were investigated separately,the AC haplotype showed a tendency to be less frequent in patients than in controls(OR(AG/AC)0.78; 95%CI,0.57-1.06). CONCLUSION:The-765GG genotype is associatedwith an increased risk of developing CRC and the GG/ AC haplotype seems to protect against CRC.These findings suggest a modulating role for the COX-2 polymorphisms-765G→C and-1195A→G in the development of CRC in a Dutch population.Juliёt H Hoff Rene HM te Morsche Hennie MJ Roelofs Elise MJ van der Logt Fokko M Nagengast Wilbert HM Peters 2009World Journal of Gastroenterology2009,15,36:6
17冷冻面团发酵技术在中式食品中的应用 Ⅱ.冰结构蛋白对鲜酵母及包子类冷冻面团流变发酵特性的影响显示文摘应用 F3 流变发酵仪和动态流变仪研究冰结构蛋白(ISP)对冻藏 0、1、2、3、4 周鲜酵母发酵特性和冷冻面团动态流变学特性的影响。结果表明:随着冻藏时间延长,所有酵母样品发酵过程中气体释放曲线最大高度H′m、产生CO2 气体总体积V总及面团最大膨胀高度Hm 均逐渐降低,冷冻面团的弹性模量(G′)和黏性模量(G 〞)逐渐下降,冷冻面团包子比容显著减小。引入冰结构蛋白(ISP)后,冻藏时间相同时,酵母发酵过程中的 H′m、V 总及Hm 均有所增大,G′和 G 〞下降趋势减缓,冷冻面团包子比容明显大于空白组,说明ISP 能够抑制冻藏过程中冰晶的形成和重结晶,减弱冰晶对酵母及面筋蛋白质网络结构的破坏,同时也说明ISP 能够增强面筋蛋白质网络结构的强度,提高面筋蛋白质对冰晶破坏的抵抗力。任士贤 黄卫宁 王宏兹 堵国成 廖祥儒 贾春利 RAYAS-DUAR TE Patricia 2009食品科学2009,30,23:6
18The role of photovaporization of the prostate in small volume benign prostatic hyperplasia and review of the literature显示文摘Objective:Our objective was to characterize the safety and efficacy of the 180 W XPS-GreenLight laser in men with lower urinary tract symptoms secondary to a small volume benign prostatic hyperplasia(BPH).Methods:A retrospective analysis was performed for all patients who underwent 180 W XPSlaser photoselective vaporization of the prostate(PVP)vaporization of the prostate between 2012 and 2016 at two-tertiary medical centers.Data collection included baseline comorbidities,disease-specific quality of life scores,maximum urinary flow rate(Qmax),postvoid residual(PVR),complications,prostate volume and prostate-specific antigen(PSA).The secondary endpoints were the incidence of intraoperative and postoperative adverse events.Complications were stratified using the Clavien-Dindo grading system up to 90 days after surgery.Results:Mean age of men was 67.8 years old,with a mean body mass index of 29.7 kg/m2.Mean prostate volume as measured by transrectal ultrasound was 29 mL.Anticoagulation use was 47%and urinary retention with catheter at time of surgery was 17%.Mean hospital stay and catheter time were 0.5 days.Median follow-up time was 6 months with the longest duration of follow-up being 22.5 months(interquartile range,3-22.5 months).The International Prostate Symptom Score improved from 22.8±7.0 at baseline to 10.7±7.4(p<0.01)and 6.3±4.4(p<0.01)at 1 and 6 months,respectively.The Qmax improved from 7.70±4.46 mL/s at baseline to 17.25±9.30 mL/s(p<0.01)and 19.14±7.19 mL/s(p<0.001)at 1 and 6 months,respectively,while the PVR improved from 216.0±271.0 mL preoperatively to 32.8±45.3 mL(p<0.01)and 26.2±46.0 mL(p<0.01)at 1 and 6 months,respectively.The PSA dropped from 1.97±1.76 ng/mL preoperatively to 0.71±0.61 ng/mL(p<0.01)and 0.74±0.63 ng/mL at 1 and 6 months,respectively.No patient had a bladder neck contracture postoperatively and no capsular perforations were noted intraoperatively.Conclusion:The 180 W GreenLight XPS system is safe and effective for men with small volume BPH.PVP produced improvements in symptomatic and clinical parameters without any safety concern.It represents a safe surgical option in this under studied population.Dominique Thomas Kevin C.Zorn Malek Meskawi Ramy Goueli Pierre-Alain Hueber Lesa Deonarine Vincent Misrai Alexis Te Bilal Chughtai 2019Asian Journal of Urology2019,6,4:6
19MPK14-mediated auxin signaling controls lateral root development via ERF13-regulated very-long-chain fatty acid biosynthesis显示文摘Auxin plays a critical role in lateral root(LR)formation.The signaling module composed of auxin-response factors(ARFs)and lateral organ boundaries domain transcription factors mediates auxin signaling to control almost every stage of LR development.Here,we show that auxin-induced degradation of the APETALA2/Ethylene Responsive Factor(AP2/ERF)transcription factor ERF13,dependent on MITOGENACTIVATED PROTEIN KINASE MPK14-mediated phosphorylation,plays an essential role in LR development.Overexpression of ERF13 results in restricted passage of the LR primordia through the endodermal layer,greatly reducing LR emergence,whereas the erf13 mutants showed an increase in emerged LR.ERF13 inhibits the expression of 3-ketoacyl-CoA synthase16(KCS16),which encodes a fatty acid elongase involved in very-long-chain fatty acid(VLCFA)biosynthesis.Overexpression of KCS16 or exogenous VLCFA treatment rescues the LR emergence defects in ERF13 overexpression lines,indicating a role downstream of the auxin-MPK14-ERF13 signaling module.Collectively,our study uncovers a novel molecular mechanism by which MPK14-mediated auxin signaling modulates LR development via ERF13-regulated VLCFA biosynthesis.Bingsheng Lv Kaijing Wei Kongqin Hu Te Tian Feng Zhang Zipeng Yu Dajian Zhang Yinghua Su Yalin Sang Xiansheng Zhang Zhaojun Ding 2021Molecular Plant2021,14,2:6
20Human amniotic epithelial cell feeder layers maintain mouse embryonic stem cell pluripotency via epigenetic regulation of the c-Myc promoter显示文摘老鼠胚胎的干细胞(转换字符) 在老鼠的 feeder 层上典型地是有教养的胚胎的成纤维细胞(MEF ) ,与白血病,禁止的因素(LIF ) 增加了处于一个无差别的状态维持他们。我们以前证明了人的羊膜的上皮的房间(hAECs ) 能被用作 feeder 房间维持老鼠转换字符 pluripotency,但是为这的机制是未知的。在现在的学习,我们发现那 CpG 5 c-Myc 基因仍然是的岛在在 hAECs 上有教养的老鼠转换字符的 hypomethylated。另外,在 c-Myc 基因倡导者 histone H3 的 acetylation 和 histone H3K4 的 trimethylation 铺平比在在 MEF 上有教养的 ES 房间的那些在在 hAECs 上有教养的 ES 房间是更高的。这些数据建议 hAECs 能经由 c-Myc 的 epigenetic 修正改变鼠标转换字符基因表示,提供为处于一个无差别的状态的转换字符的导致 hAEC 的维护的可能的机制。Te Liu Weiwei Cheng Tianjin Liu Lihe Guo Qin Huang Lizhen Jiang Xiling Du Fuhui Xu Zhixue Liu Dongmei Lai 2010Acta Biochimica et Biophysica Sinica2010,42,2:6
返回顶部 每页显示:
共814页 首页 上一页 第1页 下一页 末页 /814 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费