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| 1 | Use of isolated Roux loop for pancreaticojejunostomy reconstruction after pancreaticoduodenectomy显示文摘AIM: To evaluate the efficacy of the isolated Roux loop technique in decreasing the frequency of pancreaticojejunal anastomosis failure. METHODS: We retrospectively reviewed 88 consecutive patients who underwent pancreaticoduodenectomy (standard or pylorus-preserving). Single jejunal loop was used in 42 patients (SL group) while isolated Roux loop was used in 46 patients (RL group). Demographic characteristics (age, gender) and perioperative results (major/minor complications, mortality, hospital stay) were compared between the two groups. RESULTS: Mortality was almost equal in both groups and overall mortality was 2.27%. Leak rate from the pancreaticojejunal anastomosis and hospital stay were lower in the RL group without significant difference. Morbidity was 39.1% in the RL group, insignificantly higherthan the SL group. Operative time was almost 30 min longer in the RL group. CONCLUSION: The isolated Roux loop, although an equally safe alternative, does not present advantages over the traditional use of a single jejunal loop. Randomized controlled studies are required to further clarify its efficacy. | Konstantinos Ballas Nikolaos Symeonidis Savvas Rafailidis Theodoros Pavlidis Georgios Marakis Nikolaos Mavroudis Athanasios Sakantamis | 2010 | World Journal of Gastroenterology2010，16，25： | 4 |
| 2 | Effect of early propranolol administration on portal hypertensive gastropathy in cirrhotic rats显示文摘AIM:To investigate any protective effect of early propranolol administration in the development of portal hypertensive gastropathy in cirrhotic rats. METHODS:For the development of liver cirrhosis and portal hypertensive gastropathy,60 rats underwent ligation of the left adrenal vein and complete devascularization of the left renal vein,followed by phenobarbital and carbon tetrachloride(CCl4) administration.After two weeks of CCl4 administration, the rats were randomly separated into two groups.In group A,propranolol was continuously administered intragastrically throughout the study,whereas in group B normal saline(placebo)was administered instead. Hemodynamic studies and vascular morphometric analysis of gastric sections were performed after complete induction of cirrhosis. RESULTS:Vascular morphometric studies showed higher numbers of vessels in all mucosal layers in the control group.Statistical analysis revealed a significantly higher total vascular surface in the control group compared to the propranolol group,but with no statistically significant difference between the mean vascular surfaces between the groups.Our study clearly shows that the increased mucosal blood flow is manifested by a marked increase of vessel count. CONCLUSION:Early propranolol's administration in portal hypertensive cirrhotic rats seems to prevent intense gastric vascular congestion that characterizes portal hypertensive gastropathy. | Savas Rafailidis Charalampos Demertzidis Konstantinos Ballas Michail Alatsakis Nikolaos Symeonidis Theodoros Pavlidis Kyriakos Psarras Valentini Tzioufa-Asimakopoulou Athanassios Sakadamis | 2009 | World Journal of Gastroenterology2009，15，34： | 3 |
| 3 | Intravenous fosfomycin for the treatment of nosocomial infections caused by carbapenem-resistent Klebsiella pneumoniae in critically ill patients: a prospective evaluation显示文摘 | Michalopoulos A Virtzili S Rafailidis P | 2010 | Clin Microbiollnfect2010，16，2： | 1 |
| 4 | Ampicillin/sulbactam:current status in severe bacterial infections显示文摘 | Rafailidis PI Ioannidou EN Falagas ME | 2007 | Drugs2007，6713，： | 1 |
| 5 | Resistance to polymyxins: Mechanisms, frequency and treatment options显示文摘 | Falagas M E Rafailidis P I Matthaiou D K | 2010 | Drug Resist Updat2010，13，45： | 1 |
| 6 | Frequency of the off-label use of antibiotics in clinical practice: a system- atie review显示文摘 | Tansarlid GS Rafailidis PI Kapaskelis A | 2012 | Expert Rev Anti Infect Ther2012，10，12： | 1 |
| 7 | Attributable mortality of acine- tobacter baumannii:No longer a controversial issue显示文摘 | Falagas ME Rafailidis PI | 2007 | Critical Care2007，11，3： | 1 |
| 8 | A- mpicillin/sulbactam:current status in severe bacterial in- fections 显示文摘 | RAFAILIDIS P I IOANNIDOU E N FALAGAS M E | 2007 | Drugs2007，67，13： | 1 |
| 9 | Ampicillin/sulbactam:current status in severe bacterial infections显示文摘 | Rafailidis PI Ioannidou EN Falagas ME | | 0，，13： | 1 |
| 10 | Ampicillin/sulbactam: current status in severe bacterial infections显示文摘 | Rafailidis PI Ioannidou EN Falagas ME | 2007 | Drugs2007，67，13： | 1 |
| 11 | Severe cytomegalovirus infection in apparently immunocompetent patients: a systematic review显示文摘 | Rafailidis Pl Mourtzoukou EG Varbobitis IC | 2008 | Virol J2008，5，： | 1 |
| 12 | Colistin therapy for micro-biologically documented multidrug-resistant gram-negative bacterial infections:a retrospective cohort study of 258patients显示文摘 | Falagas ME Rafailidis PI Ioannidou E | 2010 | Int J Antimicrob Agents2010，35，2： | 1 |
| 13 | Wind-tunnel numerical modeling of flow and dispersion about several building shapes显示文摘 | Meroney B N Leitl B M Rafailidis S | 1999 | Journal of Wind Engineering and Industrial Aerodynamics1999，，81： | 1 |
| 14 | Current diagno-sis and management of infectious mononucleosis显示文摘 | Vouloumanou EK Rafailidis PI Falagas ME | 2012 | CurrOpin Hematol2012，19，1： | 1 |
| 15 | Risk factors associated with the isolation of colistin-resistant gram-negative bacteria:a matched case-control study显示文摘 | Matthaiou D K Michalopoulos A Rafailidis P I | 2008 | Crit Care Med2008，36，3： | 1 |
| 16 | Options for treating carbapen- em-resistant Enterobacteriaeeae显示文摘 | Rafailidis PI Falagas ME | 2014 | Curt Opin Infect Dis2014，27，6： | 1 |
| 17 | Carbapenems versus altemative antibiotics for the treatment of bacteraemia due to Enterobacteriaceaeproducing extended-spectrum β-lactamases:a systematic review and meta-analysis显示文摘 | Vardakas KZ Tansarli GS Rafailidis PI | 2012 | J Antimicrob Chemother2012，67，12： | 1 |
| 18 | Ampieiltin/sulbactam: current status in severe bacterial infections显示文摘 | Rafailidis PI Ioannidou EN Falagas ME | 2007 | Drugs2007，67，13： | 1 |
| 19 | Arrhythmias associated with fluoroquinolone therapy显示文摘 | Falagas ME Rafailidis PI Rosmarakis ES | 2007 | Int J Antimicrob Agents2007，29，4： | 1 |
| 20 | Synergy of fosfomycin with other antibiotics for Gram-positive and Gram-negative bacteria显示文摘 | Kastoris AC Rafailidis PI Vouloumanou EK | 2010 | Eur J Clin Pharmacol2010，66，4： | 1 |
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