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| 1 | Pharmacologic rationale for treatments of peritoneal surface malignancy from colorectal cancer显示文摘The peritoneal surfaces of the abdomen and pelvis are important sites for the dissemination of gastrointestinal and gynecologic malignancy. Transcoelomic dissemination of cancer cells gives rise to carcinomatosis, which, without special treatment, is a fatal manifestation of these diseases. To treat peritoneal carcinomatosis, cytoreductive surgery removes gross disease plus perioperative intraperitoneal and perioperative intravenous chemotherapy eradicates microscopic residual disease and chemical compatibilities. Chemotherapy agents are administered either by the intraperitoneal or intravenous route, based on their pharmacologic properties. A peritoneal-plasma barrier, which retards the clearance of high molecular weight chemotherapy from the peritoneal cavity, results in a large exposure of small cancer nodules on abdominal and pelvic surfaces. Tissue penetration of the intraperitoneal chemotherapy is facilitated by moderate hyperthermia (41-42℃). Targeting of intravenous chemotherapy to the peritoneal surface is facilitated by the intraperitoneal heat. A constant dose of chemotherapy agent and volume of carrier solution, based on body surface area, allows prediction of systemic drug exposure and systemic toxicity. Timing of the hyperthermic chemotherapy as a scheduled part of the surgical procedure to uniformly expose all peritoneal surfaces is crucial to success. | PaulH Sugarbaker Kurt Vander Speeten O Anthony Stuart | 2010 | World Journal of Gastrointestinal Oncology2010，2，1： | 4 |
| 2 | Acute Intramural Hematoma of the Aorta: A Mystery in Evolution显示文摘 | Arturo Evangelista Debabrata Mukherjee Rajendra H. Mehta Patrick T. O’Gara Rossella Fattori Jeanna V. Cooper Dean E. Smith Jae K. Oh Stuart Hutchison Udo Sechtem Eric M. Isselbacher Christoph A. Nienaber Linda A. Pape Kim A. Eagle | 2005 | Circulation2005，，8： | 2 |
| 3 | 10-1800 MHz Dielectric properties of fresh apples during storage显示文摘 | GUO Wenchuan STUART O NELSON | 2007 | Journal of Food Engineering2007，83，4： | 1 |
| 4 | The Geography of Opportunity: Spatial Heterogeneity in Founding Rates and the Performance of Bioteehnology Firms 显示文摘 | STUART T SORENSON O | 2003 | Research Policy2003，32，2： | 1 |
| 5 | Effects of Cardiac Resynchronization on Disease Progression in Patients With Left Ventricular Systolic Dysfunction, an Indication for an Implantable Cardioverter-Defibrillator, and Mildly Symptomatic Chronic Heart Failure显示文摘 | William T. Abraham James B. Young Angel R. León Stuart Adler Alan J. Bank Shelley A. Hall Randy Lieberman L Bing Liem John B. O’Connell John S. Schroeder Kevin R. Wheelan | 2004 | Circulation2004，，18： | 1 |
| 6 | Efficacy of interpersonal psychotherapy for postpartum depression 显示文摘 | O' Hara MW Stuart S Gorman LL | 2000 | Arch GenPsychiatry2000，57，6： | 1 |
| 7 | Changes in global gene expression patterns during development and maturation of the rat kidney显示文摘 | Stuart R O Bush K T Nigam S K | 2001 | Proc Natl Acad Sci U S A2001，98，10： | 1 |
| 8 | Hematopoiesis : an evolving paradigm for stem cell biology 显示文摘 | STUART H O LEONARD I Z | 2008 | Cell2008，132，： | 1 |
| 9 | Rival penalized competitive learning (RPCL) : a topology-determining algorithm for analyzing gene expression data 显示文摘 | NAIR T M ZHENG C L FINK J L STUART R O GRIBSKOV M | 2003 | Computational Biology and Chemistry2003，27，6： | 1 |
| 10 | MCMC methods for functions:modifying old algorithms to make them faster显示文摘 | COTTER S L ROBERTS G O STUART A M | 2013 | Statistical Science2013，28，3： | 1 |
| 11 | Syndication networks andthe spatial distribution of venture capital investments 显示文摘 | SORENSON O STUART T E | 2001 | American Journal of2001，106，6： | 1 |
| 12 | The BH3-Only Proteins Bim and Puma Cooperate to Impose Deletional Tolerance of Organ-Specific Antigens显示文摘 | Daniel H.D. Gray Fiona Kupresanin Stuart P. Berzins Marco J. Herold Lorraine A. O’Reilly Philippe Bouillet Andreas Strasser | 2012 | Immunity2012，，3： | 1 |
| 13 | Youth gang affiliation, violence, and criminal activities: A review of motivational, risk, and protective factors显示文摘 | Kate O’Brien Michael Daffern Chi Meng Chu Stuart D.M. Thomas | 2013 | Aggression and Violent Behavior2013，，4： | 1 |
| 14 | Modeling of peptide adsorption interactions with a poly(lactic acid)surface显示文摘 | O'Brien CP Stuart SJ Bruce DA | 2008 | Langmuir2008，24，14： | 1 |
| 15 | 10-1800MHz Dielec-tricpropertiesof fresh apples during storage显示文摘 | GUO Wenchuan STUART O NELSON S el at | | 0，，： | 1 |
| 16 | Effective treatment for postpartum depression is not sufficient to improve the development mother-child relationship显示文摘 | Forman DR O Hara MW Stuart S | 2007 | Development and Psychopathology2007，19，2： | 1 |
| 17 | The modification of infectiousbronchitis virus of chickens as result of propagation in embry-onated chicken eggs显示文摘 | DelaPlane J P Stuart H O | 1941 | Rhode Island University Agri ExPCultural Exp Station Bulletin1941，284，： | 1 |
| 18 | Microwave dielectric method for the rapid, non-destructive determination of bulk density and moisture content ofpeanut hull pellets显示文摘 | Samir Trabelsi Ana M Paz Stuart O Nelson | 2013 | 115:332-3382013，115，： | 1 |
| 19 | Efficacy of interpersonal psychotherapy for postpartum depression 显示文摘 | O' Hara MW Stuart S Gorman LL | 2000 | Arch Gen Psychiatry2000，57，： | 1 |
| 20 | Fomannoxin, a phytotoxic metabolite of Fomes annosus:in vitro production, host toxicity and isolation from naturally infected Sitka spruce heartwood显示文摘 | M C Heslin M R Stuart P O Murchu and D MX Donnelly | 1983 | European Journal Forest Pathology1983，，13： | 1 |
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