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| 1 | Sentinel-lymph-node resection compared with conventional axillary-lymph-node dissection in clinically node-negative patients with breast cancer: overall survival findings from the NSABP B-32 randomised phase 3 trial显示文摘 | David N Krag Stewart J Anderson Thomas B Julian Ann M Brown Seth P Harlow Joseph P Costantino Takamaru Ashikaga Donald L Weaver Eleftherios P Mamounas Lynne M Jalovec Thomas G Frazier R Dirk Noyes André Robidoux Hugh MC Scarth Norman Wolmark | 2010 | Lancet Oncology2010，，10： | 3 |
| 2 | SLC26A4 mutation testing for hearing loss associated with enlargement of the vestibular aqueduct显示文摘Pendred syndrome(PS) is characterized by autosomal recessive inheritance of goiter associated with a defect of iodide organification, hearing loss, enlargement of the vestibular aqueduct(EVA), and mutations of the SLC26A4 gene. However, not all EVA patients have PSor SLC26A4 mutations. Two mutant alleles of SLC26A4 are detected in 1/4 of North American or European EVA populations, one mutant allele is detected in another 1/4 of patient populations, and no mutations are detected in the other 1/2. The presence of two mutant alleles of SLC26A4 is associated with abnormal iodide organification, increased thyroid gland volume, increased severity of hearing loss, and bilateral EVA. The presence of a single mutant allele of SLC26A4 is associated with normal iodide organification, normal thyroid gland volume, less severe hearing loss and either bilateral or unilateral EVA. When other underlying correlations are accounted for, the presence of a cochlear malformation or the size of EVA does not have an effect on hearing thresholds. This is consistent with observations of an Slc26a4 mutant mouse model of EVA in which hearing loss is independent of endolymphatic hydrops or inner ear malformations. Segregation analyses of EVA in families suggest that the patients carrying one mutant allele of SLC26A4 have a second, undetected mutant allele of SLC26A4, and the probability of a sibling having EVA is consistent with its segregation as an autosomal recessive trait. Patients without any mutations are an etiologically heterogeneous group in which siblings have a lower probability of having EVA. SLC26A4 mutation testing can provide prognostic information to guide clinical surveillance and management, as well as the probability of EVA affecting a sibling. | Taku Ito Julie Muskett Parna Chattaraj Byung Yoon Choi Kyu Yup Lee Christopher K Zalewski Kelly A King Xiangming Li Philine Wangemann Thomas Shawker Carmen C Brewer Seth L Alper Andrew J Griffith | 2013 | World Journal of Otorhinolaryngology2013，3，2： | 2 |
| 3 | Landscape features and weather influence nest survival of a ground-nesting bird of conservation concern,the greater sage-grouse,in humanaltered environments显示文摘Introduction:Ground-nesting birds experience high levels of nest predation.However,birds can make selection decisions related to nest site location and characteristics that may result in physical,visual,and olfactory impediments to predators.Methods:We studied daily survival rate[DSR]of greater sage-grouse(Centrocercus urophasianus)from 2008 to 2010 in an area in Wyoming experiencing large-scale alterations to the landscape.We used generalized linear mixed models to model fixed and random effects,and a correlation within nesting attempts,individual birds,and years.Results:Predation of the nest was the most common source of nest failure(84.7%)followed by direct predation of the female(13.6%).Generally,landscape variables at the nest site(≤30 m)were more influential on DSR of nests than features at larger spatial scales.Percentage of shrub canopy cover at the nest site(15-m scale)and distances to natural gas wells and mesic areas had a positive relationship with DSR of nests,whereas distance to roads had a negative relationship with DSR of nests.When added to the vegetation model,maximum wind speed on the day of nest failure and a 1-day lag in precipitation(i.e.,precipitation the day before failure)improved model fit whereby both variables negatively influenced DSR of nests.Conclusions:Nest site characteristics that reduce visibility(i.e.,shrub canopy cover)have the potential to reduce depredation,whereas anthropogenic(i.e.,distance to wells)and mesic landscape features appear to facilitate depredation.Last,predators may be more efficient at locating nests under certain weather conditions(i.e.,high winds and moisture). | Stephen L Webb Chad V Olson Matthew R Dzialak Seth M Harju Jeffrey B Winstead Dusty Lockman | 2012 | Ecological Processes2012，1，1： | 2 |
| 4 | Technical outcomes of sentinel-lymph-node resection and conventional axillary-lymph-node dissection in patients with clinically node-negative breast cancer: results from the NSABP B-32 randomised phase III trial显示文摘 | David N Krag Stewart J Anderson Thomas B Julian Ann M Brown Seth P Harlow Takamaru Ashikaga Donald L Weaver Barbara J Miller Lynne M Jalovec Thomas G Frazier R Dirk Noyes André Robidoux Hugh MC Scarth Denise M Mammolito David R McCready Eleftherios P Mamo | 2007 | Lancet Oncology2007，，10： | 2 |
| 5 | Cardiac resynchronization therapy for the treatment of heart failure in patients with intraventricular conduction delay and malignant ventricular tachyarrhythmias显示文摘 | Steven L Higgins John D Hummel Imran K Niazi Michael C Giudici Seth J Worley Leslie A Saxon John P Boehmer Michael B Higginbotham Teresa De Marco Elyse Foster Patrick G Yong | 2003 | Journal of the American College of Cardiology2003，，8： | 2 |
| 6 | 显示文摘 | Seth M L Raychaudhuri S P Investigations on the relationship of new brinjal mosaic virus and its vector Aphis gossypii Glov | 1977 | Acta Botanica Indica1977，5，2： | 1 |
| 7 | Multivariate granger causality and generalized variance显示文摘 | Barrett A B Barnett L Seth A K | 2010 | Physical Review E2010，81，04： | 1 |
| 8 | Developments in destructive and non-destructive pathway for selective desulfurization in oil-biorefining processes 显示文摘 | SETH L FARINELLI P DI MARTINO S | 1999 | Applied Microbiology and Biotechnology1999，52，1： | 1 |
| 9 | Muscle contributions to propulsion and support during running 显示文摘 | HAMNER S R SETH A DELP S L | 2010 | J Biom2010，43，14： | 1 |
| 10 | Pigmentary Disorders 显示文摘 | JEAN L B SETH J O | 2000 | Melanotype Biology2000，，1： | 1 |
| 11 | Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia显示文摘 | Seth R Lide L Elizabeta N | 2005 | Blood2005，105，4： | 1 |
| 12 | Amalnerkar,Surface cupricated SnO2-ZnO Thick Films as a H2S Gas Sensor显示文摘 | Wagh M S Patil L A Tanay Seth D P | 2004 | Materials Chemistry and Physics2004，84，23： | 1 |
| 13 | Efficacy of postoperative patient - controlled and continuous ifusion epidural analgesia versus intravenous patient controlled analgesia with opioi- da 显示文摘 | CHRISTOPHER L W SETH R COHEN B C | 2005 | Anrsthesiology2005，103，6： | 1 |
| 14 | Polymerase chain reaction in clinically suspected genitourinary tuberculosis: comparison with intravenous urography, bladder biopsy, and urine acid fast bacilli culture显示文摘 | A.K Hemal N.P Gupta T.P Rajeev Rajeev Kumar L Dar P Seth | 2000 | Urology2000，，4： | 1 |
| 15 | The distribution of Δ5 polyene acids in some pine seed oils between the α- and β-chains by 13C-NMR spectroscopy 显示文摘 | D Frank Gunstone Shirley Seth L Robert | 1995 | Chemistry and Physics of Lipids1995，78，7： | 1 |
| 16 | Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3显示文摘 | Seth RB Sun L Ea CK | 2005 | Ce112005，122，： | 1 |
| 17 | Anergy induction by dimeric TCR ligands显示文摘 | Appel H Seth NP Gauthier L | 2001 | J lmmunol2001，166，： | 1 |
| 18 | Gen-eralized averaging method for power conversion circuits显示文摘 | SETH R S MARK N J XIAOJUN Z L | 1991 | IEEE Trans on Power Electronics1991，6，2： | 1 |
| 19 | Muscle contributions to pro-pulsion and support during running 显示文摘 | Hamner S R Seth A Delp S L | 2010 | Journal of biomechanics2010，43，14： | 1 |
| 20 | Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NFkappaB and IRF 3显示文摘 | Seth RB Sun L Ea CK | 2005 | Cell2005，122，5： | 1 |
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