|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Intraductal endoscopic radiofrequency ablation for the treatment of hilar non-resectable malignant bile duct obstruction显示文摘AIM: To evaluate the safety and technical success of endoscopic radiofrequency ablation(RFA) for palliative treatment of malignant hilar bile duct obstruction. METHODS: In this study, a recently CE and FDA-approved endoscopic RFA catheter was first tested in an ex vivo pig liver model to study the effect of electrosurgical variables on the extent of the area of induced necrosis. Subsequently, a retrospective analysis was conducted of all patients treated with endoscopic RFA for malignant biliary obstruction at our center between February 2012 and April 2013. All patients received an additional plastic stent implantation into the biliary tree following RFA. RESULTS: In the pig model, ablation time of 60-90 seconds using the bipolar soft coagulation mode at 8-10 watts with an effect of 8 was found to be the most feasible setting. Twelve patients(5 females, 7 males; mean age, 70 years) underwent 19 endoscopic RFA(range, 1-5) sessions. Deployment of RFA was successful in all patients. Systemic chemotherapy was administered in four patients. We observed biliary bleeding 4-6 wk after the intervention in three cases and two of these patients died: in one patient, spontaneous hemobilia occurred, whereas bleeding started during stent extraction in the other. In the third patient, bleeding was stopped by insertion of a non-covered self-expanding metal stent. Another three patients developed cholangitis during follow-up. Seven patients died during follow-up and median survival was 6.4 mo(95%CI: 0.05-12.7) from the time of the first RFA. CONCLUSION: Endoscopic RFA is an easy to perform and technically highly successful procedure. However, hemobilia possibly associated with RFA occurred in three of our patients. Therefore, larger prospective studies are needed to further evaluate the safety and efficacy of this promising new method. | Andrea Oliver Tal Johannes Vermehren Mireen FriedrichRust Jrg Bojunga Christoph Sarrazin Stefan Zeuzem Jrg Trojan Jrg Gerhard Albert | 2014 | World Journal of Gastrointestinal Endoscopy2014，6，1： | 18 |
| 2 | Performance of Transient Elastography for the Staging of Liver Fibrosis: A Meta-Analysis显示文摘 | Mireen Friedrich–Rust Mei–Fang Ong Swantje Martens Christoph Sarrazin Joerg Bojunga Stefan Zeuzem Eva Herrmann | 2008 | Gastroenterology2008，，4： | 6 |
| 3 | SEMS vs cSEMS in duodenal and small bowel obstruction:High risk of migration in the covered stent group显示文摘AIM:To compare clinical success and complications of uncovered self-expanding metal stents(SEMS)vs covered SEMS(cSEMS)in obstruction of the small bowel.METHODS:Technical success,complications and outcome of endoscopic SEMS or cSEMS placement in tumor related obstruction of the duodenum or jejunum were retrospectively assessed.The primary end points were rates of stent migration and overgrowth.Secondary end points were the effect of concomitant biliary drainage on migration rate and overall survival.The data was analyzed according to the Strengthening the Reporting of Observational Studies in Epidemiology guidelines.RESULTS:Thirty-two SEMS were implanted in 20 patients.In all patients,endoscopic stent implantation was successful.Stent migration was observed in 9 of16 cSEMS(56%)in comparison to 0/16 SEMS(0%)implantations(P=0.002).Stent overgrowth did not significantly differ between the two stent types(SEMS:3/16,19%;cSEMS:2/16,13%).One cSEMS dislodged and had to be recovered from the jejunum by way of laparotomy.Time until migration between SEMS and cSEMS in patients with and without concomitant biliary stents did not significantly differ(HR=1.530,95%CI0.731-6.306;P=0.556).The mean follow-up was 57±71 d(range:1-275 d).CONCLUSION:SEMS and cSEMS placement is safe in small bowel tumor obstruction.However,cSEMS is accompanied with a high rate of migration in comparison to uncovered SEMS. | Oliver Waidmann Jrg Trojan Mireen Friedrich-Rust Christoph Sarrazin Wolf Otto Bechstein Frank Ulrich Stefan Zeuzem Jrg Gerhard Albert | 2013 | World Journal of Gastroenterology2013，19，37： | 4 |
| 4 | Clinical utility of the ARCHITECT HCV Ag assay for early treatment monitoring in patients with chronic hepatitis C genotype 1 infection显示文摘 | Johannes Vermehren Simone Susser Annemarie Berger Dany Perner Kai-Henrik Peiffer Regina Allwinn Stefan Zeuzem Christoph Sarrazin | 2012 | Journal of Clinical Virology2012，，1： | 3 |
| 5 | Acoustic Radiation Force Impulse Elastography for fibrosis evaluation in patients with chronic hepatitis C: An international multicenter study显示文摘 | Ioan Sporea Simona Bota Markus Peck-Radosavljevic Roxana Sirli Hironori Tanaka Hiroko Iijima Radu Badea Monica Lupsor Carmen Fierbinteanu-Braticevici Ana Petrisor Hidetsugu Saito Hirotoshi Ebinuma Mireen Friedrich-Rust Christoph Sarrazin Hirokazu Takahash | 2012 | European Journal of Radiology2012，，12： | 3 |
| 6 | The role of resistance in HCV treatment显示文摘 | Johannes Vermehren Christoph Sarrazin | 2012 | Best Practice & Research Clinical Gastroenterology2012，，4： | 2 |
| 7 | SCH 503034, a Novel Hepatitis C Virus Protease Inhibitor, Plus Pegylated Interferon α-2b for Genotype 1 Nonresponders显示文摘 | Christoph Sarrazin Regine Rouzier Frank Wagner Nicole Forestier Dominique Larrey Samir K. Gupta Musaddeq Hussain Amrik Shah David Cutler Jenny Zhang Stefan Zeuzem | 2007 | Gastroenterology2007，，4： | 2 |
| 8 | Entecavir plus tenofovir combination as rescue therapy in pre-treated chronic hepatitis B patients: An international multicenter cohort study显示文摘 | Jorg Petersen Vlad Ratziu Maria Buti Harry L.A. Janssen Ashley Brown Pietro Lampertico Jan Schollmeyer Fabien Zoulim Heiner Wedemeyer Martina Sterneck Thomas Berg Christoph Sarrazin Marc Lutgehetmann Peter Buggisch | 2011 | Journal of Hepatology2011，，3： | 2 |
| 9 | Antiviral strategies in hepatitis C virus infection显示文摘 | Christoph Sarrazin Christophe Hézode Stefan Zeuzem Jean-Michel Pawlotsky | 2012 | Journal of Hepatology2012，，： | 2 |
| 10 | Understanding female sport at trition in a stereotypical male sport within the framework of Eccle' s expectancy value model 显示文摘 | Guillet Sarrazin Fontayne | 2006 | Psychology of Women Quarterly2006，30，： | 1 |
| 11 | Endocan or endothelial cell specific molecule-1 (ESM-1):a potential novel endothelial cell marker and a new target for cancer therapy显示文摘 | Sarrazin S Adam E Lyon M | 2006 | Biochim Biophys Acta2006，1765，1： | 1 |
| 12 | Endocan or endothelial cell specific molecule-1 -(ESM-1):a potential novel endothelial cell marker and a new target for cancer therapy显示文摘 | Sarrazin S Adam E Lyon M | | 0，，01： | 1 |
| 13 | Contribution to understanding parabolic oxidation kinetics of dilute alloys Part Ⅱ:Oxides with metal deficit or oxygen excess显示文摘 | Sarrazin Pierre Galerie Alain Caillet Marcel | | 0，，3： | 1 |
| 14 | Characterization of the inhibition of hepatitis C virus entry by in vitro-generated and patient-derived oxidized low-density lipoprotein显示文摘 | Westhaus S Bankwitz D Ernst S Rohrmann K Wappler I AgnéC Luchtefeld M Schieffer B Sarrazin C Manns M P Pietschmann T Ciesek S von Hahn T | 2013 | Hepatology2013，57，5： | 1 |
| 15 | 13C-methacetin Breath Test Shortened: 2-point-measurements After 15 Minutes Reliably Indicate the Presence of Liver Cirrhosis显示文摘 | Arne Schneider Wolfgang F. Caspary Rebecca Saich Christoph F. Dietrich Christoph Sarrazin Wilhelm Kuker Barbara Braden | 2007 | Journal of Clinical Gastroenterology2007，，： | 1 |
| 16 | Reduced incidence of vagally induced atrial fibrillation and expression levels of connexins by n-3 polyunsaturated fatty acids in dogs 显示文摘 | SARRAZIN J F COMEAU G DALEAU P | 2007 | J Am Coil Cardiol2007，50，15： | 1 |
| 17 | Resistance to direct antiviral agents in patients with hepatitis C virus infection显示文摘 | Sarrazin C Zeuzem S | 2010 | Gastroen terology2010，138，2： | 1 |
| 18 | Motivation and dropout in female handballers:s 21-month prospec-tive study显示文摘 | Sarrazin P Vallerand R Guillet E | | 0，，： | 1 |
| 19 | M-CSF instructs myeloid lineage fate in single haematopoietic stem cells显示文摘 | Mossadegh-Keller N Sarrazin S Kandalla PK | 2013 | Nature2013，497，7448： | 1 |
| 20 | The lumbar anterior epidural cavity:the posterior longitudinal ligament,the anterior ligaments of the dura mater and the anterior internal vertebral venous plexus显示文摘 | Plaisant O Sarrazin J L Cosnard G | | 0，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员