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1中国慢性病前瞻性研究:研究方法和调查对象的基线特征显示文摘目的探讨环境、个体生活方式、体格和生化指标以及遗传易感性等因素对中国成年人主要慢性病发生、发展的影响。方法中国慢性病前瞻性研究为一项建立有生物样本库的超大型前瞻性队列研究。2004--2008年在城市和农村各5个地区开展基线调查,包括问卷调查、体格检查和血液样本采集。2008年对随机抽取5%的队列成员进行第一次重复调查。通过常规和定向监测对队列成员进行长期全死因监测和四类主要慢性病的发病监测,并从全民医疗保险数据库获取个体全病种入院诊疗信息。结果基线调查共人选30~79(平均51.5)岁512891名对象。其中男性占41.0%,农村人群占55.9%。队列人群男女性现在吸烟率分别为61.3%和2.4%;男性过去一年中每周至少一次饮酒率为33.4%,女性为2.1%;超重肥胖(BMI≥24.0kg/m2)率,男性为41.8%,女性为45.3%;调查时SBP≥140mmHg或DBP≥90mmHg(1mmHg=1.33kPa)的比例男性为32.2%,女性为30.2%。不同年龄、性别和地区各主要调查指标均有差异。结论中国不同地区、年龄、性别及出生年代人群具有不同的慢性病暴露谱。李立明 吕筠 郭彧 Rory Collins 陈君石 Richard Peto 吴凡 陈铮鸣 2012中华流行病学杂志2012,33,3:142
2Petawatt and exawatt class lasers worldwide显示文摘In the 2015 review paper‘Petawatt Class Lasers Worldwide’a comprehensive overview of the current status of highpower facilities of>200 TW was presented.This was largely based on facility specifications,with some description of their uses,for instance in fundamental ultra-high-intensity interactions,secondary source generation,and inertial confinement fusion(ICF).With the 2018 Nobel Prize in Physics being awarded to Professors Donna Strickland and Gerard Mourou for the development of the technique of chirped pulse amplification(CPA),which made these lasers possible,we celebrate by providing a comprehensive update of the current status of ultra-high-power lasers and demonstrate how the technology has developed.We are now in the era of multi-petawatt facilities coming online,with 100 PW lasers being proposed and even under construction.In addition to this there is a pull towards development of industrial and multi-disciplinary applications,which demands much higher repetition rates,delivering high-average powers with higher efficiencies and the use of alternative wavelengths:mid-IR facilities.So apart from a comprehensive update of the current global status,we want to look at what technologies are to be deployed to get to these new regimes,and some of the critical issues facing their development.Colin N.Danson Constantin Haefner Jake Bromage Thomas Butcher Jean-Christophe FChanteloup Enam A.Chowdhury Almantas Galvanauskas Leonida A.Gizzi Joachim Hein David I.Hillier Nicholas W.Hopps Yoshiaki Kato Efim A.Khazanov Ryosuke Kodama Georg Korn Ruxin Li Yutong Li Jens Limpert Jingui Ma Chang Hee Nam David Neely Dimitrios Papadopoulos Rory R.Penman Liejia Qian Jorge J.Rocca andrey A.Shaykin Craig W.Siders Christopher Spindloe Sándor Szatmári Raoul M.G.M.Trines Jianqiang Zhu Ping Zhu Jonathan D.Zuegel 2019High Power Laser Science and Engineering2019,7,3:33
3中国急性心肌梗死和梗死后2级预防治疗状况调查显示文摘目的 :了解我国各医院对急性心肌梗死 (AMI)临床诊治以及出院后长期 2级预防治疗的基本模式。方法 :在全国选择较有代表性的 2 5 0 0余家医院 ,采用统一问卷的方式对各院心血管病主管医生进行调查。结果 :本次调查共收回有效问卷 1919份 ,应答率为 77%。调查显示 ,具有降低死亡等积极疗效的抗血小板、静脉溶栓和血管紧张素转换酶抑制剂 (ACEI)等药物已成为我国AMI治疗的常规手段。 90 %左右的被调查医生对这些药物的疗效均有明确认识。 82 %的医生认为 β 受体阻滞剂对AMI有积极疗效 ,但有 5 0 %左右医生以选择性使用为主 ,且用药剂量很小 (约为国外常用剂量的 1/4) ,开始使用的时间也相对较迟。一些对改善患者预后并无积极疗效的药物 (如硫酸镁、钙通道阻滞剂 )或疗效尚不明确的药物 (如中药制剂 ,蛇毒等 )常规使用的情况仍较为普遍 ,尤其是硫酸镁 (47% )和中药制剂 (45 % )。在AMI后的 2级预防中 ,除阿司匹林外 ,对其余几类有效的治疗药物常规使用比例均较低 ,包括ACEI(5 0 % ) ,β 受体阻滞剂 (35 % )和他汀类降胆固醇药物 (2 5 % )。 结论 :目前我国AMI和梗死后 2级预防药物治疗模式与欧美等国家基本相似 ,但仍有不够规范之处。尤其是一些已被证明并无积极疗效的药物使用过度 。蒋立新 陈铮鸣 谢晋湘 Rory Collin Richard Peto 刘力生 2002临床心血管病杂志2002,18,9:30
4应用于三维生物打印的DNA超分子水凝胶显示文摘水凝胶因其高含水量和类似于细胞外基质的特点,是三维组织打印和人工器官制备的首选基材,也因此成为化学、材料学和生命医学领域研究的热点[1]。截止目前,用于生物打印的水凝胶主要包括海藻酸钠、壳聚糖、胶原蛋白、琼脂糖等天然水凝胶及其衍生产物,以及人工合成的聚乙二醇、聚多肽等化学类水凝胶[2]。无论是天然的物理类水凝胶还是人工合成的化学类水凝胶。李闯 Alan Faulkner-Jones Alison R. Dun 金娟 陈平 邢永政 杨忠强 李志波 舒文淼 刘冬生 Rory R. Duncan 2015中国科学基金2015,29,3:18
5A history of high-power laser research and development in the United Kingdom显示文摘The first demonstration of laser action in ruby was made in 1960 by T.H.Maiman of Hughes Research Laboratories,USA.Many laboratories worldwide began the search for lasers using different materials,operating at different wavelengths.In the UK,academia,industry and the central laboratories took up the challenge from the earliest days to develop these systems for a broad range of applications.This historical review looks at the contribution the UK has made to the advancement of the technology,the development of systems and components and their exploitation over the last 60 years.Colin N.Danson Malcolm White John R.M.Barr Thomas Bett Peter Blyth David Bowley Ceri Brenner Robert J.Collins Neal Croxford A.E.Bucker Dangor Laurence Devereux Peter E.Dyer Anthony Dymoke-Bradshaw Christopher B.Edwards Paul Ewart Allister I.Ferguson John M.Girkin Denis R.Hall David C.Hanna Wayne Harris David I.Hillier Christopher J.Hooker Simon M.Hooker Nicholas Hopps Janet Hull David Hunt Dino A.Jaroszynski Mark Kempenaars Helmut Kessler Sir Peter L.Knight Steve Knight Adrian Knowles Ciaran L.S.Lewis Ken S.Lipton Abby Littlechild John Littlechild Peter Maggs Graeme P.A.Malcolm OBE Stuart P.D.Mangles William Martin Paul McKenna Richard O.Moore Clive Morrison Zulfikar Najmudin David Neely Geoff H.C.New Michael J.Norman Ted Paine Anthony W.Parker Rory R.Penman Geoff J.Pert Chris Pietraszewski Andrew Randewich Nadeem H.Rizvi Nigel Seddon MBE Zheng-Ming Sheng David Slater Roland A.Smith Christopher Spindloe Roy Taylor Gary Thomas John W.G.Tisch Justin S.Wark Colin Webb S.Mark Wiggins Dave Willford Trevor Winstone 2021High Power Laser Science and Engineering2021,9,2:5
6基于位置识别的移动学习系统5R自适应框架显示文摘如何利用移动设备的位置识别功能开发创新性的移动应用系统,是众多研究者和商业应用开发者关注的焦点。基于位置识别的移动学习系统5R自适应框架为实现自适应移动学习环境提供了一套解决方案和标准化结构。5R自适应框架能够根据学习者、位置、时间、移动设备等因素自动生成学习者所需要的学习内容,增强学习者与学习情境之间的交互。5R自适应框架的实施需要描述基于位置的学习内容并使之标签化,建立自适应约束条件和学习内容之间的关系。在基于位置识别的地理课实地考察移动学习过程中,5R自适应框架能够很好地支持这一应用,而且在实现过程中体现出高度的灵活性。QingTan Xiaokun Zhang Kinshuk Rory McGreal 孙洪涛(编译) 石鹏峰(编译) 2012现代远程教育研究2012,24,3:5
7未来货币政策的构建:政策工具选择显示文摘全球金融危机爆发后,很多OECD经济体设立了新型货币政策工具。未来的经济环境与危机时期相比有诸多不同,与危机前相比更宽泛的金融稳定概念已成为货币政策重要目标,本文分析了未来哪些货币政策新工具需要保留,并分析了在向常态化经济转型过渡期间可以选择哪些货币政策新工具,以及如果经济陷入长期停滞又该如何选择这些工具。在后复苏时期,央行可以回归到盯住短期市场利率和缩小资产负债表。然而,新的流动性监管要求可能需要货币政策实施有所改变。向常态化经济转型过渡会是一个漫长的过程,需要组合使用各种流动性工具。同时,央行可以采用利率走廊下限体系,维护金融稳定。作为降低政策利率的替代品,非传统货币政策措施必要性降低,除非经济陷入长期停滞。在后复苏时期,仍然可以延续扩大抵押品和交易对方范围,推广央行间货币互换。Kei-Ichiro Inaba Rory O'Farrell ?ukasz Rawdanowicz Ane Kathrine Christensen 盖新哲 朱尘 2016国际金融研究2016,,3:4
8Two-dimensional gel electrophoresis in bacterial proteomics显示文摘Two-dimensional gel electrophoresis(2-DE)is a gel-based technique widely used for analyzing the pro-tein composition of biological samples.It is capable of resolving complex mixtures containing more than a thousand protein components into individual protein spots through the coupling of two orthogonal bio-physical separation techniques:isoelectric focusing(first dimension)and polyacrylamide gel electrophore-sis(second dimension).2-DE is ideally suited for ana-lyzing the entire expressed protein complement of a bacterial cell:its proteome.Its relative simplicity and good reproducibility have led to 2-DE being widely used for exploring proteomics within a wide range of envi-ronmental and medically-relevant bacteria.Here we give a broad overview of the basic principles and his-torical development of gel-based proteomics,and how this powerful approach can be applied for studying bacterial biology and physiology.We highlight specific 2-DE applications that can be used to analyze when,where and how much proteins are expressed.The links between proteomics,genomics and mass spectrometry are discussed.We explore how proteomics involving tandem mass spectrometry can be used to analyze(post-translational)protein modifications or to identify proteins of unknown origin by de novo peptide se-quencing.The use of proteome fractionation tech-niques and non-gel-based proteomic approaches are also discussed.We highlight how the analysis of pro-teins secreted by bacterial cells(secretomes or exo-proteomes)can be used to study infection processes or the immune response.This review is aimed at non-specialists who wish to gain a concise,compre-hensive and contemporary overview of the nature and applications of bacterial proteomics.Shirly O.T.Curreem Rory M.Watt Susanna K.P.Lau Patrick C.Y.Woo 2012Protein & Cell2012,3,5:4
9The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression显示文摘Thomas Derrien Rory Johnson Giovanni Bussotti Andrea Tanzer Sarah Djebali Hagen Tilgner Gregory Guernec David Martin Angelika Merkel David G. Knowles Julien Lagarde Lavanya Veeravalli Xiaoan Ruan Yijun Ruan Timo Lassmann Piero Carninci James B. Brown Leon 2012Genome Research2012,,9:3
10Resolution of phylogenetic relationships of the major subfamilies of the Delphacidae (Homoptera: Fulgoroidea) using the mitochondrial ribosomal DNA显示文摘到亚科的从类水平的 Delphacid 关系完全被解决了(在那些之中征税一检验) 用从 12S 的 3'' 结束的顺序数据, gene.Monophyly, non-asiracine,亚科强烈被支持, asiracine Ugyops 被放在最树的基础位置。支持层次为 monophyly 在 weighting transversions 以后的 Delphaciniincreased 更重重地比转变并且在把 cixiidoutgroup 从数据集移开以后。在 Delphacini 之中, Conomelus 和 Megamelus 比也到过 Chloriona 与对方有关仔细是更多。这些结果基于词法人物与树一致。然而,与词法数据相对照我们的结果强烈在之间的 supportedasister 组关系 Stenocraninae 和 Kelisiinae。尽管 12S 基因碎片在 Chloriona 以内关于种类关系给了一些信息,既不这碎片也不 16S 基因的 5'' 结束看起来为这水平很有用。Molecularevolutionary 模式提供了在从 T 的基础作文有移动到 Aduring 的证据 non-Asiracinae 的早进化。non-Asiracinae 也有比较地快的替换率,这二观察可能被相关。在“现代”的 delphacidChloriona, AT 内容在没有限制的区域是比较地低的,但是这为“非现代”的 delphacids 不是事实。为缬氨酸的 tRNA 是在其它地方的 translocated,可能从对方在 Delphacidae 和 Cixiidae 前分叉。EDDY DIJKSTRA MICHEL A. SLOTMAN RORY J. POST 2006Insect Science2006,13,3:3
11Wearable multifunctional printed graphene sensors显示文摘The outstanding properties of graphene have initiated myriads of research and development;yet, its economic impact is hamperedby the difficulties encountered in production and practical application. Recently discovered laser-induced graphene is generated bya simple printing process on flexible and lightweight polyimide films. Exploiting the electrical features and mechanical pliability ofLIG on polyimide, we developed wearable resistive bending sensors that pave the way for many cost-effective measurementsystems. The versatile sensors we describe can be utilized in a wide range of configurations, including measurement of force,deflection, and curvature. The deflection induced by different forces and speeds is effectively sensed through a resistancemeasurement, exploiting the piezoresistance of the printed graphene electrodes. The LIG sensors possess an outstanding range forstrain measurements reaching >10% A double-sided electrode concept was developed by printing the same electrodes on bothsides of the film and employing difference measurements. This provided a large bidirectional bending response combined withtemperature compensation. Versatility in geometry and a simple fabrication process enable the detection of a wide range of flowspeeds, forces, and deflections. The sensor response can be easily tuned by geometrical parameters of the bending sensors and theLIG electrodes. As a wearable device, LIG bending sensors were used for tracking body movements. For underwater operation,PDMS-coated LIG bending sensors were integrated with ultra-low power aquatic tags and utilized in underwater animal speedmonitoring applications, and a recording of the surface current velocity on a coral reef in the Red Sea.Altynay Kaidarova Mohammed Asadullah Khan Marco Marengo Liam Swanepoel Alexander Przybysz Cobus Muller Andreas Fahlman Ulrich Buttner Nathan R.Geraldi Rory P.Wilson Carlos M.Duarte Jurgen Kosel 2019npj Flexible Electronics2019,3,1:2
12深圳证券交易所结构设计显示文摘深圳证券交易所塔楼采用钢梁-型钢混凝土柱组合框架+钢筋混凝土核心筒结构体系,东西两侧外框架在裙楼以下采用转换桁架结构。位于塔楼7-10层的悬臂裙楼最大悬挑距离37m,采用钢桁架结构支承。本项目为超高、超限结构,受地震作用及风荷载影响较大,设计时基于不同性能水准下的抗震性能目标,同时考虑风洞试验风荷载数据,对结构设计方案及整体性能进行了研究。弹性分析采用了两种不同的分析软件进行计算对比,同时对塔楼进行了非线性时程分析。分析结果表明,本工程整体结构性能满足相关规范要求,结构设计安全,构件设计主要由风荷载或重力荷载控制。罕遇地震下结构抗震性能满足"大震不倒"的性能目标。朴才思 Rory McGowan 何伟明 李秀英 张然 2014建筑结构2014,44,24:2
13Incremental Prognostic Value of Myocardial Perfusion Single Photon Emission Computed Tomography for the Prediction of Cardiac Death: Differential Stratification for Risk of Cardiac Death and Myocardial Infarction显示文摘Rory Hachamovitch Daniel S. Berman Leslee J. Shaw Hosen Kiat Ishac Cohen J. Arthur Cabico John Friedman George A. Diamond 1998Circulation1998,,6:2
14Adenosquamous Carcinoma of the Pancreas: A Single-Institution Experience Comparing Resection and Palliative Care显示文摘Rory L. Smoot Lizhi Zhang Thomas J. Sebo Florencia G. Que 2008Journal of the American College of Surgeons2008,,3:2
15Water crisis?显示文摘Rory Clarke 2003OECD observer2003,19,:2
16Chronic pancreatitis显示文摘Joan M Braganza Stephen H Lee Rory F McCloy Michael J McMahon 2011The Lancet . 2011 (9772)2011,,:2
17Unselfish giants? Understanding China and India as security providers显示文摘Rory Medcalf 2012Australian Journal of International Affairs2012,,5:2
18血清胆固醇与癌症死亡率的前瞻性定群研究显示文摘李婉先 Rory,C 1993中华流行病学杂志1993,14,1:2
19Prognostic Significance of Myocardial Fibrosis in Hypertrophic Cardiomyopathy显示文摘Rory O’Hanlon Agata Grasso Michael Roughton James C. Moon Susan Clark Ricardo Wage Jessica Webb Meghana Kulkarni Dana Dawson Leena Sulaibeekh Badri Chandrasekaran Chiara Bucciarelli-Ducci Ferdinando Pasquale Martin R. Cowie William J. McKenna Mary N. Shep 2010Journal of the American College of Cardiology2010,,11:2
20In vitro evidence for role of ERK, p38, and JNK in exocrine pancreatic cytokine production显示文摘Isaac Samuel Asgar Zaheer Rory A. Fisher 2006Journal of Gastrointestinal Surgery2006,,10:2
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