|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | What are the key elements of a sustainable university显示文摘 | Rebeka Lukman Peter Glavic | | 0，，09： | 1 |
| 2 | Caspase-9, caspase-3 and easpase-7 have distinct roles during in- trinsic apoptosis显示文摘 | MATTHEW B LUIS R M REBEKA L D G | 2013 | BMC Cell Biology2013，，14： | 1 |
| 3 | Differences in abuse report- ed by female and male Canadian medical students显示文摘 | Rebeka Moscarello Katalin J Margittai | 1994 | CAN MED ASSOC J1994，150，3： | 1 |
| 4 | Rheological study of interactions between non-ionic surfactants and polysac- eharide thickeners used in textile printing显示文摘 | Rebeka Fijan Sonja Sostar-Turka Romano Lapasin | 2007 | Carbohydrate Poly- mers2007，68，4： | 1 |
| 5 | Slow disease progression and robust therapy-mediated CD4^+ T-cell recovery are associated with efficient thymopoiesis during HIV-1 infection 显示文摘 | Marie-Lise Dion Rebeka Bordi Joumana Zeidan | 2007 | Blood2007，109，7： | 1 |
| 6 | Indicators of Activity-Friendly Communities显示文摘 | Laura K. Brennan Ramirez Christine M. Hoehner Ross C. Brownson Rebeka Cook C. Tracy Orleans Marla Hollander Dianne C. Barker Philip Bors Reid Ewing Richard Killingsworth Karen Petersmarck Thomas Schmid William Wilkinson | 2006 | American Journal of Preventive Medicine2006，，6： | 1 |
| 7 | Fostering collaboration between universities regarding regional sustainability initiatives-the University of Maribor显示文摘 | Rebeka Lukman Damjan Krajnc Peter Glavic | 2009 | Journal of Cleaner Production2009，，11： | 1 |
| 8 | Multilayered nano-foils for low-temperature metal-ceramic joining显示文摘 | Karlo T Raic Rebeka Rudolf | 2008 | Assoe Metall Eng Serbia2008，14，2： | 1 |
| 9 | Muhilayered nano-foils for low-temperature metal-ceramic joining 显示文摘 | KARLOT R REBEKA R ALEKSANDAR T IVAN A | 2008 | Metalurgija-Journal of Metallurgy2008，，14： | 1 |
| 10 | Stress dependent electrical resistivity of orthodontic wire from the shape memory alloy NiTi 显示文摘 | Janko Fercec Ivan Anzel Rebeka Rudolf | 2014 | Materials and Design2014，55，： | 1 |
| 11 | Review of sustainability terms and their definitions显示文摘 | Peter Glavi? Rebeka Lukman | 2007 | Journal of Cleaner Production2007，，18： | 1 |
| 12 | Review of sustainability terms and their definitions显示文摘 | Peter Glavic Rebeka Lukman | 2007 | Joumal ofCleanerProduction2007，，15： | 1 |
| 13 | Clinicopathological significance of KU70/KU80, a key DNA damage repair protein in breast cancer显示文摘 | Alaa T. Alshareeda Ola H. Negm Nada Albarakati Andrew R. Green Christopher Nolan Rebeka Sultana Srinivasan Madhusudan Ahmed benHasouna Paddy Tighe Ian O. Ellis Emad A. Rakha | 2013 | Breast Cancer Research and Treatment2013，，2： | 1 |
| 14 | Serological evidence of Toxoplasma gondii infection as potential risk for the development of lepromatous leprosy in an endemic area for both neglected tropical diseases in Brazil显示文摘Background:Mycobacterium leprae and Toxoplasma gondii infections are both neglected tropical diseases highly prevalent in Brazil.Infection with certain parasite species can significantly alter susceptibility to other important pathogens,and/or influence the development of pathology.Here we investigated the possible influence of M.leprae/T.gondii co-parasitism on the manifestation of leprosy and its clinical forms.Methods:Participants(n=291)were recruited in Campos dos Goytacazes city,Rio de Janeiro state,southeast Brazil,from August 2015 to December 2019 and clinically diagnosed for leprosy.Participants were selected based on the presence(patients)or absence(healthy controls)of the leprosy disease.Contacts of patients were also recruited for this study.Serum samples from patients(n=199)with leprosy,contacts(n=40)and healthy controls(n=52)were investigated for levels of IgM and IgG anti-phenolic glycolipid-1(PGL-1)by ELISA.Additionally,IgG antibody against soluble Toxoplasma antigen(STAg)was measured in sera samples from leprosy patients,contacts and healthy controls for Toxoplasma gondii serology by ELISA.Anti-PGL-1 IgG and IgM levels were compared using one-way ANOVA Kruskal-Wallis or Mann-Whitney,while Spearman test was used to correlate levels of IgG anti-STAg and IgM/IgG anti-PGL-1 from seropositive and seronegative individuals for T.gondii infection.The risk of T.gondii infection for leprosy disease was assessed using Fisher’s test.Results:Levels of IgM anti-PGL-1 antibodies were significantly higher in multibacillary(MB)patients compared to paucibacillary(PB)patients(P=0.0068).Higher IgM and IgG levels anti-PGL-1 were detected in patients with the lepromatous forms.The serologic prevalence for T.gondii infection was 74.9%.We detected increased anti-STAg antibody levels in leprosy patients(79.4%),reaching 88.8%within those with lepromatous form of this disease.The leprosy risk increase in T.gondii seropositive individuals was two-fold(odds ratio[OR]=2.055;95% confidence intervals[95%CI]:1.18–3.51)higher than those seronegative,and considering the lepromatous leprosy risk this increase was even dramatic(OR=4.33;95%CI:1.76–9.69)in T.gondii seropositive individuals.Moreover the leprosy risk in T.gondii seropositive individuals was weakly correlated to the levels of IgG anti-STAg and IgM/IgG anti-PGL-1.Conclusions:Altogether,our results suggest that T.gondii infection may exert immunomodulatory properties that influence to the susceptibility of leprosy,mainly on its more severe clinical form.A better understanding of parasite immunomodulation can ultimately contribute to the development of medical applications. | Luciana Regina Pereira Oliveira Lívia Mattos Martins Rebeka da Conceição Souza Yuri Scheidegger de Castro Letícia Silva Nascimento Juliana Azevedo da Silva Edilbert Pellegrini Nahn Junior Wilmar Dias da Silva Alba Lucínia Peixoto-Rangel | 2020 | Infectious Diseases of Poverty2020，9，1： | 0 |
| 15 | Restoration of Motor Function through Delayed Intraspinal Delivery of Human IL-10-Encoding Nucleoside-Modified mRNA after Spinal Cord Injury显示文摘Efficient in vivo delivery of anti-inflammatory proteins to modulate the microenvironment of an injured spinal cord and promote neuroprotection and functional recovery is a great challenge.Nucleoside-modified messenger RNA(mRNA)has become a promising new modality that can be utilized for the safe and efficient delivery of therapeutic proteins.Here,we used lipid nanoparticle(LNP)-encapsulated human interleukin-10(hIL-10)-encoding nucleoside-modified mRNA to induce neuroprotection and functional recovery following rat spinal cord contusion injury.Intralesional administration of hIL-10 mRNA-LNP to rats led to a remarkable reduction of the microglia/macrophage reaction in the injured spinal segment and induced significant functional recovery compared to controls.Furthermore,hIL-10 mRNA treatment induced increased expression in tissue inhibitor of matrix metalloproteinase 1 and ciliary neurotrophic factor levels in the affected spinal segment indicating a time-delayed secondary effect of IL-105 d after injection.Our results suggest that treatment with nucleoside-modified mRNAs encoding neuroprotective factors is an effective strategy for spinal cord injury repair. | LászlóGál Tamás Bellák Annamária Marton Zoltán Fekécs Drew Weissman Dénes Török Rachana Biju Csaba Vizler Rebeka Kristóf Mitchell B.Beattie Paulo J.C.Lin Norbert Pardi Antal Nógrádi Krisztián Pajer | 2023 | Research2023，，4： | 0 |
| 16 | Capsaicin-sensitive afferentation represents an indifferent defensive pathway from eradication in patients with H.pylori gastritis显示文摘AIM:To study the role of capsaicin-sensitive afferent nerves in Helicobacter pylori (H.pylori) positive chronic gastritis before and after eradication.METHODS:Gastric biopsy samples were obtained from corpus and antrum mucosa of 20 healthy human subjects and 18 patients with H.pylori positive chronic gastritis (n=18) before and after eradication.Tradi-tional gastric mucosal histology (and Warthin-Starry silver impregnation) and special histochemical examina-tions were carried out.Immunohistochemistry for cap-saicin receptor (TRVP1),calcitonin gene-related peptide (CGRP) and substance P (SP) were carried out by the labeled polymer immunohistological method (Lab VisionCo.,USA) using polyclonal rabbit and rat monoclonal antibodies (Abcam Ltd.,UK).RESULTS:Eradication treatment was successful in 16 patients (89%).Seven patients (7/18,39%) re-mained with moderate complaints,meanwhile 11 pa-tients (11/28,61%) had no complaints.At histological evaluation,normal gastric mucosa was detected in 4 patients after eradication treatment (4/18,22%),and moderate chronic gastritis could be seen in 14 (14/18,78%) patients.Positive immuno-staining for capsaicin receptor was seen in 35% (7/20) of controls,89% (16/18,P < 0.001) in patients before and 72% (13/18,P < 0.03) after eradication.CGRP was positive in 40% (8/20) of controls,and in 100% (18/18,P < 0.001) of patients before and in 100% (18/18,P < 0.001) after eradication.The immune-staining of gastric mucosa for substance-P was positive in 25% (5/20) of healthy con-trols,and in 5.5% (3/18,P > 0.05) of patients before and in 0% of patients (0/18,P > 0.05) after H.pylori eradication.CONCLUSION:Distibution of TRVP1 and CGRP is altered during the development of H.pylori positive chronic gastritis.The immune-staining for TRVP1,CGRP and SP rwemained unchanged before and after H.py-lori eradication treatment.The capsaicin-sensitive affer-entation is an independent from the eradication treat-ment.The 6 wk time period might not be enough time for the restituion of chronic H.pylori positive chronic gastritis.The H.pylori infection might not represent the main pathological factor in the development of chronic | Lilla Lakner András Dmtr Csaba Tóth Imre L Szabó gnes Meczker Rebeka Hajós László Kereskai Gyrgy Szekeres Zoltán Dbrnte Gyula Mózsik | 2011 | World Journal of Gastrointestinal Pharmacology and Therapeutics2011，2，5： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员