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| 1 | 子宫颈癌筛查异常妇女处理的共识指南(2006版)显示文摘2001年,美国阴道镜与宫颈病理学会(American Society for Colposcopyand Cervical Pathology,ASCCP)联合其他专业学会以及联邦与国际组织.制订了2001版的宫颈癌细胞学筛查结果异常妇女处理的共识指南。这是全面的、以循证医学为依据的指南,其目的是帮助所有亚专业的临床医生,处理每年约480万诊断为细胞学异常的美国妇女。 | 李志刚(翻译) Thomas C. Wright Jr L Stewart Massad Charles J. Dunton MarkSpitzer Edward J. Wilkinson DianeSolomon | 2008 | 循证医学2008，8，4： | 16 |
| 2 | 肥胖和动脉老化:Whitehall Ⅱ队列主动脉僵硬度纵向研究显示文摘该研究旨在确定肥胖症是否中年后动脉硬化加速的独立预测因子。纳入Whitehall Ⅱ研究受试者男性3789例,女性1383例,平均年龄66岁,均接受颈-股动脉压检测,4年后再次进行测定。一般肥胖状况由体质量指数,中心肥胖由腰围和腰臀比,脂肪含量百分比由身体阻抗来评估。通过线性混合模型,对年龄、性别、种族和平均动脉压进行调整后,所有肥胖症测量指标与主动脉硬化[通过随访的脉搏波传导速度(pulse wave velocity,PWV)较基线增加值来确定]相关。 | 刘莉 叶鹏 Brunner EJ Shipley MJ Ahmadi-Abhari S Tabak AG McEniery CM Wilkinson IB Marmot MG Singh-Manoux A Kivimaki M | 2015 | 中华高血压杂志2015，23，6： | 8 |
| 3 | Anisotropy of mechanical properties and crystallographic texture in hot rolled AZ31+XSr sheets显示文摘The influences of Sr on the microstructure,texture and mechanical properties including flow and anisotropy behavior of AZ31 alloys are investigated.Slabs containing no,0.4 and 0.8 wt%of strontium were cast and subjected to hot rolling.Results indicate that Sr reduces the basal texture intensity(23%in the AZ31+0.8Sr alloy)and homogenizes the distribution of strain in uniaxial tension.Furthermore,Sr increases both the strength coefficient and the strain hardening exponent in all directions.In the transverse direction,enhancements are more significant.Moreover,Sr enhances the combination of tensile strength and total elongation;i.e.,toughness,whether tests are performed parallel to the rolling,diagonal or transverse directions,to significant extents. | Alireza Sadeghi Hossein Mortezapour Javad Samei Mihriban Pekguleryuz David Wilkinson | 2019 | Journal of Magnesium and Alloys2019，7，3： | 4 |
| 4 | Autophagy in cancer biology and therapy显示文摘macroautophagy 的角色(此后 autophagy ) 在癌症,到临床的干预的生物学和反应是复杂的。autophagy 是在许多肿瘤背景的 dysregulated,是清楚的,在肿瘤开始和前进期间,并且响应治疗。然而,在控制房间行为的 autophagy 的多种的机械学的角色使在一个给定的肿瘤背景预言困难 autophagy 的角色,并且,由扩展,指向 autophagy 的治疗学的结果,力量。在这评论,我们在在癌症支持 pro-tumorigenic 和 anti-tumorigenic 和 autophagy 的治疗学的角色的文学总结证据。这概述在滋养的管理,房间死亡,房间老朽, proteotoxic 应力的规定和细胞的动态平衡包含 autophagy 的角色,在在新陈代谢的变化的肿瘤主人相互作用和参予的规定。在可能的地方,我们也试着理解,为 autophagy 的这些角色的机械学的底。我们明确地阐述在在 vivo.We 使这些问题清楚些的癌症的模型也考虑 autophagy 蛋白质的任何东西或上述所有函数怎么可能是可指向的由的遗传上设计的老鼠的新兴的角色现存或 pharmacologic 代理人的未来类。我们由简短在细胞的过程为关键 autophagy 蛋白质的子集探索不在经典中的角色得出结论,并且这些怎么可能在癌症之上影响。 | Noor GAMMOH Simon WILKINSON | 2014 | Frontiers in Biology2014，9，1： | 4 |
| 5 | 1998年印度洋珊瑚死亡事件的生态影响和社会经济影响:是ENSO影响和未来变化的警告吗?显示文摘自大约15O年前开始有气温记录以来,1998年是所记录到的最热的一年,20世纪90年代是最热的十年。另外,1998年也是有记录以来厄尔尼诺现象最严重的一年。这一现象产生的结果是,海洋中许多地方的水温很高,尤其是位于热带的印度洋的水温常常比正常年份高3~5℃。该区域内的大量珊瑚脱色并死亡,可能是由于高的水温以及其它气象、气候因子共同作用所致。斯里兰卡、马尔代夫、印度、肯尼亚、坦桑尼亚和塞舌尔群岛的珊瑚礁中珊瑚的死亡率较高,许多浅海区甚至高达90%。在位于印度洋其它地方和距海面20米以下的珊瑚礁中,珊瑚的死亡率通常为50%。因此,1998年珊瑚的死亡情况是空前严重的。印度洋的珊瑚褪色对沿海社区的二级社会经济影响可能是长期的和严重的。除了鱼资源可能减少和对旅游造成不良影响外,侵蚀可能成为一个严重的问题,尤其是在马尔代夫和塞舌尔群岛。如果目前已经发现的全球温度升高的趋势继续下去,那么1998年印度洋珊瑚礁上发生的情况在未来一些年内极有可能加剧并在其它的热带海洋区出现。印度洋的珊瑚礁可能是反映全球气候变化潜在影响的一个重要信号,我们应当对这一警告引起注意。 | Clive Wilkinson OlofLindén Herman Cesar Gregor Hodgson Jaston Rubens Alan E.Strong 李岱青 | 1999 | 人类环境杂志1999，28，2： | 4 |
| 6 | Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales显示文摘 | C.P Wilkinson Frederick L Ferris Ronald E Klein Paul P Lee Carl David Agardh Matthew Davis Diana Dills Anselm Kampik R Pararajasegaram Juan T Verdaguer | 2003 | Ophthalmology2003，，9： | 4 |
| 7 | Active earth pressure acting on retaining wall considering anisotropic seepage effect显示文摘This paper presents a general solution for active earth pressure acting on a vertical retaining wall with a drainage system along the soil-structure interface. The backfill has a horizontal surface and is composed of cohesionless and fully saturated sand with anisotropic permeability along the vertical and horizontal directions. The extremely unfavourable seepage flow on the back of the retaining wall due to heavy rainfall or other causes will dramatically increase the active earth pressure acting on the retaining walls, increasing the probability of instability. In this paper, an analytical solution to the Laplace differential governing equation is presented for seepage problems considering anisotropic permeability based on Fourier series expansion method. A good correlation is observed between this and the seepage forces along a planar surface generated via finite element analysis. The active earth pressure is calculated using Coulomb's earth pressure theory based on the calculated pore water pressures. The obtained solutions can be degenerated into Coulomb's formula when no seepage exists in the backfill. A parametric study on the influence of the degree of anisotropy in seepage flow on the distribution of active earth pressure behind the wall is conducted by varying ratios of permeability coefficients in the vertical and horizontal directions,showing that anisotropic seepage flow has a prominent impact on active earth pressure distribution. Other factors such as effective internal friction angle of soils and soil/wall friction conditions are also considered. | HU Zheng YANG Zhong-xuan Stephen Philip WILKINSON | 2017 | Journal of Mountain Science2017，14，6： | 4 |
| 8 | Baculovirus-derived hemagglutinin vaccines protect against lethal influenza infections by avian H5 and H7 subtypes显示文摘 | Crawford J Wilkinson B Vosnesensky A | 1999 | Vaccine1999，17，18： | 3 |
| 9 | 荨麻疹性皮炎的定义:皮肤过敏反应模式的一种亚型显示文摘Background: Urticarial dermatitis may represent a useful term for a subset of a reaction pattern designated most commonly as dermal hypersensitivity by pathologists. The term is not commonly used, and requires definition to determine whether it is clinically relevant. Objectives: To define urticarial dermatitis and distinguish it from other urticarial reaction patterns and to review the frequency with which dermatologists can recognize clinical settings that match the biopsy findings of urticarial dermatitis. Design: Retrospective analysis of clinical and/or histological diagnosis of urticarial dermatitis, applying strict histological criteria in a center using urticarial dermatitis as a diagnostic term in 190 archived reports. Setting: Tertiary referral dermatopathology service reporting for dermatological practices in Sydney, Australia. Main Outcome Measures: The correlation between clinical and histological diagnoses of urticarial dermatitis and alternate diagnoses was analyzed. The frequency of positive immunofluorescence findings for bullous pemphigoid was determined in a subset of patients with urticarial dermatitis in whom this test was ordered to exclude prodromal bullous pemphigoid. Results: Urticarial dermatitis was the histological diagnosis in at least 1 biopsy result in 148 patients, and matched the provisional clinical diagnosis in 49 (33.1% ) patients. Urticarial dermatitis was the only diagnosis provided in 21 patients. The main alternate clinical diagnoses provided were early bullous pemphigoid or dermatitis herpetiformis (47 patients [31.8% ]), dermatitis (39 patients [26.4% ]),drug reaction (35 patients [23.6% ]), urticarial vasculitis (24 patients [16.2% ]), and urticaria (12 patients [8.1% ]). In 91 patients with a clinical diagnosis of urticarial dermatitis, the histological diagnosis in at least 1 biopsy result was matched in 49 patients (53.8% ); other histological diagnoses included dermatitis (21 patients [23.1% ]), papular urticaria (12 patients [13.2% ]), drug reaction (6 patients [6.6% ]), and urticaria (3 patients [3.3% ]). Review of 38 direct immunofluorescent results for prodromal bullous pemphigoid and a biopsy finding of urticarial dermatitis revealed only 3 positive results (7.9% ).Conclusions: Urticarial dermatitis seems to be a useful histological and clinical term for a subset of the dermal hypersensitivityreaction pattern. Although the clinical presentation is not restricted to a specific entity, eczema and drug reactions seem to be the most frequent clinical associations; and in a subset of patients, urticarial dermatitis remains as a recognizable reaction pattern. Urticarial dermatitis without eosinophilic spongiosis is not a reliable indicator for bullous pemphigoid, because the findings of immunofluorescence are often negative. | Kossard S. Hamann I. Wilkinson B. 潘敏 | 2006 | 世界核心医学期刊文摘(皮肤病学分册)2006，2，3： | 3 |
| 10 | 儿童扩张型心肌病的发病率、病因及预后显示文摘背景:扩张型心肌病(dilated cardiomyopathy,DCM)是儿童心肌病最常见的类型,也是小儿心脏移植最常见的原因。但是,目前尚不清楚儿童DCM的流行病学特点和临床过程。
目的:详细描述儿童DCM的发病率、病因、预后及相关危险因素。
设计及地点:本项以人群为基础的前瞻性纵向队列研究入选1996年1月至2003年2月在89个儿科心脏中心诊断为DCM的儿童以及1990年1月至1995年12月在北美大型三级治疗中心诊断的患儿。
参试者:共入选1426例来自美国和加拿大的18岁以下DCM患儿。通过严格的超声心动图和/或病理学标准来诊断原发性DCM。因内分泌、免疫、药物中毒及其他原因患病者除外。
主要观测指标:每年每10万儿童的发病率、死亡率和心脏移植率。
结果:18岁以下儿童DCM每年的总发病率为0.57/10万,男孩的年发病率高于女孩(分别为0.66/10万和0.47/10万;P〈0.001),黑人的年发病率高于白人(分别为0.98/10万和0.46/10万;P〈0.001),婴儿(〈1岁)的年发病率高于儿童(分别为4.40/10万和0.34/10万;P〈0.001)。绝大部分属特发性,最常见的病因为心肌炎(46%)和神经肌肉性疾病(26%)。1年和5年死亡/移植率分别为31%和46%。死亡/移植的独立危险因素包括患儿诊断DCM时年龄较大、伴有充血性心力衰竭、左室收缩期Z评分较低以及DCM的病因(P均〈0.001)。
结论:儿童DCM有其多样性。患儿预后主要取决于病因、年龄和心力衰竭状况。人种、性别和年龄对发病率有一定影响。大部分患儿无明确病因,限制了特异性治疗。 | Jeffrey A. Towbin April M. Lowe Steven D. Colan Lynn A. Sleeper E. John Orav Sarah Clunie Jane Messere Gerald F. Cox Paul R. Lurie Daphne Hsu Charles Canter James D. Wilkinson Steven E. Lipshultz 康俊萍(译) 马长生(校) | 2007 | 美国医学会杂志(中文版)2007，26，4： | 3 |
| 11 | Speed of healing and symptom relief in grade II to IV gastroesophageal reflux disease: A meta-analysis显示文摘 | N Chiba CJ De Gara JM Wilkinson RH Hunt | 1997 | Gastroenterology1997，，6： | 3 |
| 12 | 妊娠前心血管功能与先兆子痫及胎儿生长受限的关系显示文摘妊娠期间的子痫前期和胎儿生长受限与后期母亲心血管病风险增加有关。目前尚不清楚这种关联是因果关系还是由类似的事先存在的风险因素导致。澄清这种关联需要在受孕前征募研究对象,但在方法上是困难的。 | Foo FL Mahendru AA Masini G Fraser A Cacciatore S MacIntyre DA McEniery CM Wilkinson IB Bennett PR Lees CC 刘青 叶鹏 | 2018 | 中华高血压杂志2018，26，8： | 3 |
| 13 | The publication symmetry test:a simple editorial heuristic to combat publication bias显示文摘Premier academic journals—that is, the journals in whichmany researchers must publish their work in order to maintainor advance their careers—have historically tended to rejectpapers reporting “negative” or null findings, including thosederived from “failed” attempts to replicate prior results [1–3].This tendency was likely due to three main factors. First, thelimited space available for publishing articles when journalswere printed exclusively on paper. Second, the prestige-relateddesire of “top” journals to publish new and exciting findings—i.e., “discoveries” (often taken to imply a demonstrationthat something “works,” as opposed to “fails to work”). Andthird, the difficulty posed by negative findings in terms of howthey should be interpreted: do they suggest that there is noeffect of interest to be found, or rather that the experiment,whether in its design or execution, was simply inadequate toshow the effect even though it is real [4–6]? | Brian D.Earp Dominic Wilkinson | 2017 | Journal of Clinical & Translational Research2017，3，4： | 3 |
| 14 | Tuberculosis显示文摘 | Gary Maartens Robert J Wilkinson | 2007 | The Lancet2007，，9604： | 2 |
| 15 | Shock fragmentation model for gravitational collapse显示文摘A cloud of gas collapsing under gravity will fragment.We present a new theory for this process,in which layers of shocked gas fragment due to their gravitational instability.Our model explains why angular momentum does not inhibit the collapse process.The theory predicts that the fragmentation process produces objects which are significantly smaller than most stars,implying that accretion onto the fragments plays an essential role in determining the initial masses of stars.This prediction is also consistent with the hypothesis that planets can be produced by gravitational collapse. | Michael Wilkinson Bernhard Mehlig Michael A.Morgan | 2011 | Research in Astronomy and Astrophysics2011，11，5： | 2 |
| 16 | Posterior surgical approaches to the elbow: A comparative anatomic study显示文摘 | J.Mark Wilkinson David Stanley | 2001 | Journal of Shoulder and Elbow Surgery2001，，4： | 2 |
| 17 | Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales显示文摘 | C.P Wilkinson Frederick L Ferris Ronald E Klein Paul P Lee Carl David Agardh Matthew Davis Diana Dills Anselm Kampik R Pararajasegaram Juan T Verdaguer | 2003 | Ophthalmology2003，，9： | 2 |
| 18 | MICP as a potential sustainable technique to treat or entrap contaminants in the natural environment:A review显示文摘In the last two decades,developments in the area of biomineralization has yielded promising results making it a potentially environmentally friendly technique for a wide range of applications in engineering and wastewater/heavy metal remediation.Microbially Induced Carbonate Precipitation(MICP)has led to numerous patented applications ranging from novel strains and nutrient sources for the precipitation of biominerals.Studies are being constantly published to optimize the process to become a promising,cost effective,ecofriendly approach when compared with the existing traditional remediation technologies which are implemented to solve multiple contamination/pollution issues.Heavy metal pollution still poses a major threat towards compromising the ecosystem.The removal of heavy metals is of high importance due to their recalcitrance and persistence in the environment.In that perspective,this paper reviews the current and most significant discoveries and applications of MICP towards the conversion of heavy metals into heavy metal carbonates and removal of calcium from contaminated media such as polluted water.It is evident from the literature survey that although heavy metal carbonate research is very effective in removal,is still in its early stages but could serve as a solution if the microorganisms are stimulated directly in the heavy metal environment. | Adharsh Rajasekar Stephen Wilkinson Charles K.S.Moy | 2021 | Environmental Science and Ecotechnology2021，，2： | 2 |
| 19 | An Analysis of Prospective Risk Factors for Aortic Stiffness in Men: 20-Year Follow-Up From the Caerphilly Prospective Study显示文摘 | Carmel M. McEniery Michael Spratt Margaret Munnery John Yarnell Gordon D. Lowe Ann Rumley John Gallacher Yoav Ben-Shlomo John R. Cockcroft Ian B. Wilkinson | 2010 | Hypertension2010，，1： | 2 |
| 20 | Diagnostic Yield of Spiral Enteroscopy When Performed for the Evaluation of Abnormal Capsule Endoscopy Findings显示文摘 | Jonathan M. Buscaglia Robert Richards Mark N. Wilkinson Joel R. Judah Yvette Lam Satish Nagula Peter V. Draganov | 2011 | Journal of Clinical Gastroenterology2011，，4： | 2 |
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