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| 1 | Hardy Weinberg Equilibrium in Genetic PE Research Remains Critical to Avoid Misinterpretation显示文摘 | Marcel D. Waldinger Paddy K.C. Janssen Dave H. Schweitzer | 2009 | Asian Journal of Andrology2009,11,4: | 3 |
| 2 | Rates and risk factors for suicidal ideation,suicide attempts and suicide deaths in persons with HIV:a systematic review and meta-analysis显示文摘Background People living with HIV/AIDS(PLWHA)must contend with a significant burden of disease.However,current studies of this demographic have yielded wide variations in the incidence of suicidality(defined as suicidal ideation,suicide attempt and suicide deaths).Aims This systematic review and meta-analysis aimed to assess the lifetime incidence and prevalence of suicidality in PLWHA.Methods Publications were identified from PubMed(MEDLINE),SCOPUS,OVID(MEDLINE),Joanna Briggs Institute EBP and Cochrane Library databases(from inception to before 1 February 2020).The search strategy included a combination of Medical Subject Headings associated with suicide and HIV.Researchers independently screened records,extracted outcome measures and assessed study quality.Data were pooled using a random-effects model.Subgroup and meta-regression analyses were conducted to explore the associated risk factors and to identify the sources of heterogeneity.Main outcomes were lifetime incidence of suicide completion and lifetime incidence and prevalence of suicidal ideation and suicide attempt.Results A total of 185199 PLWHA were identified from 40 studies(12 cohorts,27 cross-sectional and 1 nested case-control).The overall incidence of suicide completion in PLWHA was 10.2/1000 persons(95%CI:4.5 to 23.1),translating to 100-fold higher suicide deaths than the global general population rate of 0.11/1000 persons.The lifetime prevalence of suicide attempts was 158.3/1000 persons(95%CI:106.9 to 228.2)and of suicidal ideation was 228.3/1000 persons(95%CI:150.8 to 330.1).Meta-regression revealed that for every 10-percentage point increase in the proportion of people living with HIV with advanced disease(AIDS),the risk of suicide completion increased by 34 per 1000 persons.The quality of evidence by Grading of Recommendations,Assessment,Development and Evaluations for the suicide deaths was graded as‘moderate’quality.Conclusions The risk of suicide death is 100-fold higher in people living with HIV than in the general population.Lifetime incidence of suicidal ideation and attempts are substantially high.Suicide risk assessments should be a priority in PLWHA,especially for those with more advanced disease. | Matt Pelton Matt Ciarletta Holly Wisnousky Nicholas Lazzara Monica Manglani Djibril M Ba Vernon M Chinchillli Ping Du Anna E Ssentongo Paddy Ssentongo | 2021 | General Psychiatry2021,34,2: | 3 |
| 3 | The 5-HT2c receptor gene Cys23Ser polymorphism influences the intravaginal ejaculation latency time in Dutch Caucasian men with lifelong premature ejaculation显示文摘有终生的早泄(LPE ) 的人的坚持的短 intravaginal 射精潜伏时间(IELT ) 与 5-hydroxytryptamine (HT ) 有关是 2C 受体工作,这被要求了。这研究的目的是与 LPE 在人调查 Cys23Ser 5-HT 2C 受体基因多型性和 IELT 的持续时间的关系。因此,未来的研究与 LPE 在 64 个荷兰的白种人人被进行。基线 IELT 被秒表在一个 1 月的时期上在性交期间估计。所有人是为 Cys23Ser 5-HT 2C 受体基因多型性的 genotyped。Cys 的等位基因频率和 5-HT 2C 受体基因多型性的重量的单位变体是坚定的。在 Cys/Cys 和重量的单位 / 重量的单位遗传型和在有 LPE 的人的 IELT 的自然对数之间的协会被调查。作为结果,几何吝啬、中部、自然的吝啬的 IELT 是 25.2, 27.0, 33.9 s 分别地。所有人, 20.0% , 10.8% , 23.1% 和 41.5% 在 10 以内射精,在阴道穿入以后的 10-20, 20-30 和 30-60 s。64 个人,为 5-HT 2C 受体基因的 Cys23Ser 多型性的 Cys/Cys 和重量的单位 / 重量的单位遗传型频率分别地是 81% 和 19% 。wildtypes (Cys/Cys ) 的几何吝啬的 IELT 显著地更低(22.6 s;95% CI 18.3-27.8 s ) 比在男同型结合的异种(重量的单位 / 重量的单位)(40.4 s;95% CI 20.3-80.4 s )(P = 0.03 ) 。Cys23Ser 5-HT 2C 受体基因多型性与 LPE 在人与 IELT 被联系,这被结束。有 Cys/Cys 遗传型的人与重量的单位 / 重量的单位遗传型比人有更短的 IELT。 | Paddy KC Janssen Ron van Schaik Berend Olivier Marcel D Waldinger | 2014 | Asian Journal of Andrology2014,16,4: | 3 |
| 4 | 一种新型数字式加速度传感器原理与设计显示文摘建立了一种新型纯数字式加速度传感器的理论模型,通过检测吸合时间差检测加速度.该传感器不存在吸合电压的限制,避免了寄生电容的影响,其芯片面积远小于传统电容式加速度传感器;由于输出时间信号,可采用简单的纯数字接口电路检测.理论分析表明,质量块在两个检测电极之间的吸合时间差ΔT与加速度成正比关系,通过检测ΔT的变化即可检测加速度,其灵敏度、非线性与传统电容式加速度传感器相当.设计了一个悬臂梁-质量块结构的加速度传感器,芯片有效面积仅为0.03mm2,模拟结果显示,工作电压为8V,加速度为1gn时,吸合时间的变化ΔT为1.0554μs.采用TTL电路进行检测,其分辨率可以达到0.01gn,满量程±10gn工作时,非线性度为1.23%. | 庞洁 Lukasz Pakula Paddy French 杨恒 王跃林 | 2007 | 传感技术学报2007,20,9: | 2 |
| 5 | Menisci at a Free Liquid Surface:Surface Tension from the Maximum Pull on a Rod显示文摘 | Paddy J F Pitt A R Pashley R M | 1975 | J Chem Soc Faraday Trans1975,71,: | 1 |
| 6 | The comet-tail(A^2Πi-X^2Σ+ ) system of 12C160+ : A reinvestigation显示文摘 | Haridass C Prasad C V V Paddi R S | 2000 | J Mol Spetrosc2000,199,: | 1 |
| 7 | Monitoring of contaminated toxic and heavy metals, from mine tailings through age accumulation, in soil and some wild plants at Southeast Egypt显示文摘 | Paddy Water Rashed M N | 2010 | Journal of Hazardous Materials2010,178,: | 1 |
| 8 | The Class Nature of Women' s Oppression 显示文摘 | Paddy Quick | 1977 | Re- view of Radical Political Economics1977,9,3: | 1 |
| 9 | Stable suppression of gene expression by RNAi in mammalisn cells显示文摘 | Paddis on PJ Cana A Hanon GJ | 2002 | Proc Natl Acad Sci USA2002,99,3: | 1 |
| 10 | The Class Nature of Women's Oppression显示文摘 | Paddy Quick | 1977 | Review of Radical Political Economics1977,9,3: | 1 |
| 11 | Derangement of the E-cadherin/catenin complex is involved in transformation of differentiated to anaplastic thyroid carcinoma显示文摘 | Sam MW Hamid M Paddy N | 2006 | Am J Surg2006,19,5: | 1 |
| 12 | Detection of banned nitrofuran metabolites in animal plas- ma samples using UHPLC-MS/MS显示文摘 | Anita Radovnikovic Mary Moloney Paddy Byme | 2010 | Journal of Chromatography B2010,879,2: | 1 |
| 13 | Primary megaureter:result of surgical treatment显示文摘 | Aksnes G Imaji R Paddy A | 2002 | ANZJ Surg2002,72,: | 1 |
| 14 | The carboxyl terminus of IFN-γ contains a functional polybasic nuclear localization sequence 显示文摘 | Subramaniam PS Mujtaba MG Paddy MR | 1999 | J Biol Chem1999,274,1: | 1 |
| 15 | Zinc dialkyldithiophosphate oxidation by cumene hydroperoxide:Kinetic studies by Raman and ^31P-NMR spectroscopy显示文摘 | Paddy J L Lee N C J Waters D N | 1990 | Trib Trans1990,33,1: | 1 |
| 16 | Morphological Characterization of Some Water Yam (Dioscorea alata L.) Germplasm in Ghana显示文摘 | Michael Anokye Joseph Paddy Tettch Emmanuel Otoo | 2014 | Journal of Agricultural Science and Technology(B)2014,4,7: | 1 |
| 17 | Effectiveness of hermetic systems in controlling maize storage pests in Kenya显示文摘 | Hugo De Groote Simon C Kimenju Paddy Likhayo | 2013 | Journal of Stored Products Research2013,53,: | 1 |
| 18 | Angiotensin Ⅱ regulation of plasminogen activator inhibitor- Ⅰ gene expression in neurons of normotensive and spontaneously herpertensive rat brain 显示文摘 | Yu K Lu D Paddy MR | 1996 | Endocrinology1996,137,6: | 1 |
| 19 | Demand side management of industrial electricity consumption:promoting the use of renewable energy through real-time pricing显示文摘 | PADDY F COLIN F | 2014 | Applied Energy2014,113,: | 1 |
| 20 | Building a creative culture for innovation显示文摘 | Paddy Miller and Azra Brankovic | 2011 | Fourth Quarter2011,,11: | 1 |