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| 1 | 耐高温水基压裂液研究进展显示文摘随着勘探技术的发展,油气勘探向纵深发展,而越往深井发展地层温度越高,国内外对高温油藏的开发愈加重视。水基压裂液由于其施工方便、价格低廉以及性能优异等优点,一直是应用最为普遍的压裂液。但早期压裂液的耐温性能较差,无法满足高温油藏的压裂施工需求。因此开发可用于耐高温油气藏的水基压裂液具有重要的研究价值和实际应用价值。本文介绍了国内外耐高温水基压裂液的研究进展,对于胍胶压裂液,通过提高稠化剂用量,进行稠化剂、交联剂的改性,以提高其耐温性能;耐温清洁压裂液稠化剂类型由早期的阳离子、阴离子型向双子及复合型发展,近年还有学者将纳米体系用于改性表面活性剂;耐温合成聚合物压裂液发展较快,多是通过设计多元共聚物提升耐温能力。对于胍胶压裂液体系,研发满足特高温油藏压裂施工需求的低浓度胍胶压裂液还是今后的主要研究方向。文中指出清洁压裂液体系成本过高,无法大规模使用;合成聚合物压裂液耐温性能好,研究含有支链聚合单体或磺酸基团等的多元共聚物,引入合适的疏水基团作为稠化剂,是合成聚合物的研究方向。 | 潘一 夏晨 杨双春 马欣 MUAVMMAD Abubakar Rona 苏占全 | 2019 | 化工进展2019，38，4： | 21 |
| 2 | Psychosocial mechanisms for the transmission of somatic symptoms from parents to children显示文摘AIM: To examine familial aggregation of irritable bowel syndrome(IBS) via parental reinforcement/modeling of symptoms, coping, psychological distress, and exposure to stress.METHODS:Mothers of children between the ages of8 and 15 years with and without IBS were identified through the Group Health Cooperative of Puget Sound.Mothers completed questionnaires,including the Child Behavior Checklist(child psychological distress),the Family Inventory of Life Events(family exposure to stress),SCL-90R(mother psychological distress),and the Pain Response Inventory(beliefs about pain).Children were interviewed separately from their parents and completed the Pain Beliefs Questionnaire(beliefs about pain),Pain Response Inventory(coping)and Child Symptom Checklist[gastrointestinal(GI)symptoms].In addition,health care utilization data was obtained from the automated database of Group Health Cooperative.Mothers with IBS(n=207)and their 296 children were compared to 240 control mothers and their 335 children,while controlling for age and education.RESULTS:Hypothesis 1:reinforcement of expression of GI problems is only related to GI symptoms,but not others(cold symptoms)in children.There was no significant correlation between parental reinforcement of symptoms and child expression of GI or other symptoms.Hypothesis 2:modeling of GI symptomsis related to GI but not non-GI symptom reporting in children.Children of parents with IBS reported more non-GI(8.97 vs 6.70,P<0.01)as well as more GI(3.24 vs 2.27,P<0.01)symptoms.Total health care visits made by the mother correlated with visits made by the child(rho=0.35,P<0.001 for cases,rho=0.26,P<0.001 for controls).Hypothesis 3:children learn to share the methods of coping with illness that their mothers exhibit.Methods used by children to cope with stomachaches differed from methods used by their mothers.Only 2/16 scales showed weak but significant correlations(stoicism rho=0.13,P<0.05;acceptance rho=0.13,P<0.05).Hypothesis 4:mothers and children share psychological traits such as anxiety,depression,and somatization.Child psychological distress correlated with mother’s psychological distress(rho=0.41,P<0.001 for cases,rho=0.38,P<0.001 for controls).Hypothesis 5:stress that affects the whole family might explain the similarities between mothers and their children.Family exposure to stress was not a significant predictor of children’s symptom reports.Hypothesis 6:the intergenerational transmission of GI illness behavior may be due to multiple mechanisms.Regression analysis identified multiple independent predictors of the child’s GI complaints,which were similar to the predictors of the child’s non-GI symptoms(mother’s IBS status,child psychological symptoms,child catastrophizing,and child age).CONCLUSION:Multiple factors influence the reporting of children’s gastrointestinal and non-gastrointestinal symptoms.The clustering of illness within families is best understood using a model that incorporates all these factors. | Miranda AL van Tilburg Rona L Levy Lynn S Walker Michael Von Korff Lauren D Feld Michelle Garner Andrew D Feld William E Whitehead | 2015 | World Journal of Gastroenterology2015，21，18： | 2 |
| 3 | Social learning contributions to the etiology and treatment of functional abdominal pain and inflammatory bowel disease in children and adults显示文摘This paper reviews empirical work on cognitive and social learning contributions to the etiology and treatment of illness behavior associated with functional abdominal pain and inflammatory bowel disease. A particular emphasis is placed on randomized controlled trials, the majority of which are multi-modal in orientation, incorporating elements of cognitive behavioral therapy, social learning, and relaxation. Based on this review, we offer methodological and clinical suggestions: (1) Research investigations should include adequate sample sizes, long-term follow-up assessments, and a credible, active control group. (2) Standard gastrointestinal practice should include, when appropriate, learning opportunities for patients and family members, for example, instruction regarding the encouragement of wellness behavior. | Rona L Levy Shelby L Langer William E Whitehead | 2007 | World Journal of Gastroenterology2007，13，17： | 2 |
| 4 | Irritable Bowel Syndrome in Twins: Heredity and Social Learning Both Contribute to Etiology显示文摘 | Rona L. Levy Kenneth R. Jones William E. Whitehead Shara I. Feld Nicholas J. Talley Linda A. Corey | 2001 | Gastroenterology2001，，4： | 2 |
| 5 | αvβ3 and αvβ5 Integrin Expression in Glioma Periphery显示文摘 | Lorenzo Bello Maura Francolini Paola Marthyn Jianping Zhang Rona S. Carroll Demetrios C. Nikas Jon F. Strasser Roberto Villani David A. Cheresh Peter McL. Black | 2001 | Neurosurgery2001，，2： | 2 |
| 6 | Significance of serum carcinoembryonic antigen in metastatic breast cancer patients:A prospective study显示文摘BACKGROUND Carcinoembryonic antigen(CEA)is an important serum tumour marker with a substantial role in diagnosis and monitoring of various solid tumours.About 36%-70%of breast cancers have elevated serum CEA.And the available studies show discrepancy in addressing the prognostic significance of CEA in advanced breast cancer.AIM To estimate the serum CEA level in our metastatic breast cancer patients and correlate it with response to treatment and clinical outcome.METHODS This was a prospective clinical study conducted on 50 metastatic breast cancer patients treated at breast clinic,with newly diagnosed metastatic breast cancer planned for palliative chemotherapy,targeted therapy,and hormonal treatment.We estimated the proportion of patients with elevated serum CEA level at baseline and after palliative treatment and also studied the association of serum CEA levels with known prognostic factors.The response to treatment was correlated with the serum CEA levels in the context of responders and nonresponders.RESULTS The median pre-treatment and post-treatment CEA levels were 7.9(1.8-40.7)ng/mL and 4.39(1.4-12.15)ng/mL,respectively,in the whole study population(P=0.032).No statistically significant difference was seen in baseline serum CEA between responders and non-responders.Even in the luminal group,pretreatment serum CEA was not a predictor of response,but post-treatment CEA was a significant predictor of tumour progression.In patients with liver and lung metastases,post-treatment CEA level difference was not statistically significant in both responders and non-responders though the values were higher in nonresponders.Among those with bone metastases,69.5%had elevated post-treatment serum CEA,and only 37.5%had elevated serum CEA in those with no bone metastases.CONCLUSION Elevated post-treatment serum CEA levels are associated with disease progression and poor response to therapy.Persistently elevated post-treatment serum CEA levels are significantly associated with bone metastases.Elevated serum CEA and hormonal status are significant predictors of treatment response. | Thattungal Manoharan Anoop Rona Joseph P Saikumar Soman Steffi Chacko Mintu Mathew | 2022 | World Journal of Clinical Oncology2022，13，6： | 2 |
| 7 | Disturbed sleep:Effects of sociocultural factors and illness显示文摘 | Rona RJ Li L Gulliford MC | 1998 | Arch Dis Child1998，78，1： | 1 |
| 8 | An infarct - like myocardial lesion and other toxic manifestations produced by isoproterenol in the rat 显示文摘 | Rona G Chappel GI Balazs T Gaudry R | 1959 | Arch Pathol1959，67，： | 1 |
| 9 | Resources of the sea floor 显示文摘 | Rona P A | 2003 | Science2003，299，5607： | 1 |
| 10 | An observation of pressure waves around a shallow cavity 显示文摘 | Zhang X Rona A | 1998 | Journal of sound and vibration1998，214，4： | 1 |
| 11 | An infarct-like myocardial lesion and other toxic manifestations produced by isoproterenol in the rat显示文摘 | Rona G Chappel CI Balazs T Gaudry R | 1959 | Arch Pathol Lab Med1959，67，： | 1 |
| 12 | Disturbed sleep:effects of sociocultural factors and illness显示文摘 | RONA RJ LI L GULLIFORD MC | 1998 | Arch Dis Child1998，78，： | 1 |
| 13 | Analysis of laboratory data of 155 patients with pheochromocytoma-paraganglioma syndrome diagnosed during the past 20 years显示文摘 | BALOG B TOKE J RONA K | 2015 | Orvosi hetilap2015，156，16： | 1 |
| 14 | Acoustic imaging,visualization and quantification of buoyant hydrothermal plumes in the ocean显示文摘 | Rona P A Bemis K G Silver D | 2002 | Marine Geophysical Researches2002，23，： | 1 |
| 15 | criteria for recognition of hydrothermal minerals deposits in ocean crest 显示文摘 | Rona P A | 1987 | Economic Geology1987，73，2： | 1 |
| 16 | Active and relict sea-floor hydrothermal mineralization at the TAG hydrothermal field, Mid-Atlantic Ridge显示文摘 | Rona P A Hannington M D Raman C V | 1993 | Economic Geology1993，88，： | 1 |
| 17 | Criteria for recogmtion of hydrothermal mineral deposits in ocean crust显示文摘 | Rona P A | 1978 | Economic Geology1978，73，2： | 1 |
| 18 | Criteria for recognition of hydrothermal mineral deposits in oceanic crust显示文摘 | Rona P A | 1978 | Economic Geology1978，73，： | 1 |
| 19 | Intralesional injection of herpes simplex virus 1716 in metastatic melanoma显示文摘 | Rona M MacKie Barry Stewart S Moira Brown | 2001 | The Lancet2001，，9255： | 1 |
| 20 | Hydrothermal mineralization of oceanic ridges 显示文摘 | RONA P A | 1988 | Canadian Mineralogist1988，26，3： | 1 |
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