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| 1 | Structural and biochemical mechanism for increased infectivity and immune evasion of Omicron BA.2 variant compared to BA.1 and their possible mouse origins显示文摘The Omicron BA.2 variant has become a dominant infective strain worldwide.Receptor binding studies show that the Omicron BA.2 spike trimer exhibits 11-fold and 2-fold higher potency in binding to human ACE2 than the spike trimer from the wildtype(WT)and Omicron BA.1 strains.The structure of the BA.2 spike trimer complexed with human ACE2 reveals that all three receptor-binding domains(RBDs)in the spike trimer are in open conformation,ready for ACE2 binding,thus providing a basis for the increased infectivity of the BA.2 strain.JMB2002,a therapeutic antibody that was shown to efficiently inhibit Omicron BA.1,also shows potent neutralization activities against Omicron BA.2.In addition,both BA.1 and BA.2 spike trimers are able to bind to mouse ACE2 with high potency.In contrast,the WT spike trimer binds well to cat ACE2 but not to mouse ACE2.The structures of both BA.1 and BA.2 spike trimer bound to mouse ACE2 reveal the basis for their high affinity interactions.Together,these results suggest a possible evolution pathway for Omicron BA.1 and BA.2 variants via a human-cat-mouse-human circle,which could have important implications in establishing an effective strategy for combating SARS-CoV-2 viral infections. | Youwei Xu Canrong Wu Xiaodan Cao Chunyin Gu Heng Liu Meriting Jiang Xiaoxi Wang Qingning Yuan Kai Wu Jia Liu Deyi Wang Xianqing He Xueping Wang Su-Jun Deng H.Eric Xu Wanchao Yin | 2022 | Cell Research2022，32，7： | 6 |
| 2 | Propane Dehydrogenation over PtSnNa Catalyst Supported on La-ZSM-5 Zeolite显示文摘有 La 的不同内容的 La-ZSM-5 沸石被材料的物理化学的性质是的热水的 method.The 综合英尺红外分析的 studied.The 结果显示 La 可能被合并到分析显示出的 ZSM-5 zeolite.The NH3-TPD 的框架沸石的弱酸地点的数量与连续地增加的 La 减少了 content.Afterwards , La-ZSM-5 沸石被用作对丙烷 dehydrogenation.The 测试结果的 PtSnNa | Huang Li Zhou Yuming Zhang Yiwei Li Qingning Tian Xiaoming (School of Chemistry and Chemical Engineering,Southeast University,Nanjing 211189) | 2010 | China Petroleum Processing & Petrochemical Technology2010，12，3： | 4 |
| 3 | Geochemical characteristics of the metapelites from the Xingxingxia group in the Eastern Segment of the Central Tianshan:Implications for the provenance and paleoweathering显示文摘Metapelites from the Mesoproterozoic Xingxingxia group in the Eastern Segment of the Central Tianshan, Northwestern China, were analyzed for major and trace elements, includ-ing rare earth elements. Compared with post-Archean shales, the metapelites are enriched in Sr, Hf and Zr. The other elements are similar to the compositions of the Phanerozoic North American Shale Composite and the Post-Archean Australian average Shale (PAAS). The characteristics of Al2O3/TiO2, Cr/Zr, Cr/Th, Th/Sc and high Zr concentration suggest that these pelites could be derived from a significant proportion of felsic and a few proportion of participation of mafic mate-rials in nature. These rocks display highly fractionated REE patterns, and average (La/Yb)n = 18.6. Several samples have slightly negative Eu anomalies (Eu/Eu* = 0.7―0.84) in comparison with PAAS (Eu/Eu* = 0.65), indicating contribution from young immature materials. The low K2O/Al2O3 values of these metapelites suggest that their source materials could contain minimal alkali feldspar. In the A-CN-K triangular diagram, the sample data array intersects the feldspar join, indicating that the source had a plagioclase: K-feldspar ratio of approximately 5:1, repre-senting weathered products from components that could approximately correspond to granodio-rites and tonalites. The low Chemical Index of Alteration (CIA) and high Index of Compositional Variability (ICV) values suggest low degrees of weathering of the source and low compositional maturity of the sediments, respectively. The geochemical characteristics of the metapelites from the Xingxingxia group also demonstrate that these sediments were deposited in a back-arc background within a continental-arc system. | LI Qiugen LIU Shuwen HAN Baofu WANG Yueran DANG Qingning | 2005 | Science China Earth Sciences2005，48，10： | 4 |
| 4 | Speech enhancement by array crosstalk resistant ANC and spectrum subtraction显示文摘麦克风基于数组的讲话改进为讲话通讯和语音识别有大重要性。为了减少麦克风数组的孔并且增加,讲话改进的效果将极大地拓宽麦克风数组的申请区域。抵抗适应噪音取消方法因此是的数组串音介绍了。然后一改善光谱减法算法进一步被串联获得更好的改进结果。当它同时完成更高的 SNR 改进时,理论上的分析和实验显示建议计划需要一个仅仅很小的麦克风数组。而且,建议计划能在许多吵闹的环境被使用并且为即时实现是容易的。 | ZENG Qingning OUYANG Shan | 2008 | Chinese Journal of Acoustics2008，27，1： | 4 |
| 5 | Petrogenesis of Paleoproterozoic Luyashan charnockitic rocks in Shanxi Province: Constraints from Geochemistry and Nd isotope显示文摘Luyashan charnockite pluton 主要由二长岩, adamellite , charnockite 和 syenogranite 组成,它被 TiO 2, P 2 O 5, K 2 O , Zr , Nb , Y , Pb , La , Ce , Ba 和更高的 K 2 O/Na 2 MgO , CaO , Mg #, Th , U 和更低的 Sr 的 O 和弄空 Ba 和 Rb Ba 。在 Zr, Nb, Ce 和 SiO 2 之间的否定关联从我类型花岗石是不同的。同位素地 Luyashan charnockite plutons 在 Nd 同位素是相对一致的,显示起始的 εNd(t)( 到 -6.97) 和 Nd 的 -5.93 弄空披风模型年龄(到 2.78 Ga 的 2.67 Ga ) 。这些特征显示那 Luyashan charnockitic 岩浆从先存在导出晚太古代的外壳的来源并且与公司 2-rich 液体的在特别高的温度下面的可能的 mafic granulites 的部分融化。石榴石在部分融化期间是一个主要剩余阶段。原来的干燥 charnockitic 岩浆在早结晶化期间经历了辉石,斜长石,磷灰石,和钛铁矿的水晶分别。geochemical 证据建议 Luyashan charnockitic 岩浆可能在碰撞以后的热松驰被产生并且高举在主要碰撞以后的构造背景(∼
1850 妈) 在东方、西方的大陆人块之间。 | LIU Chaohui LIU Shuwen LI Qiugen WANG Yueran DANG Qingning GU Libing YANG Bin ZHAO Fengsan | 2006 | Progress in Natural Science:Materials International2006，16，2： | 3 |
| 6 | Effects of thermal and electrical histories on structure and dielectric behaviors of(Li_(0.5)Nd_(0.5))^(2+)-modified(Bi_(0.5)Na_(0.5))TiO_(3)-BaTiO_(3) ceramics显示文摘The effect of thermal and electrical histories on structure and dielectric behaviors is studied using 0.95(Bi_(0.5)Na_(0.5))_(0.97)(Li_(0.5)Nd_(0.5))_(0.03)TiO_(3)-0.05BaTiO_(3)(abbreviated as BNTLN0.03-BT5)ceramic as a selected system.Subtle structure change caused by annealing treatment,and pronounced phase transition and domain switching by electrical poling,are observed to occur,respectively.The dielectric constant and its strong frequency dispersion in unpoled samples decrease evidently by electrical poling due to electric field-induced ordered domain.The high temperature Maxwell-Wagner relaxor behavior vanishes by annealing treatment due to the loss of electrical inhomogeneity with interface charging effects.Piezoelectric properties are improved evidently by annealing treatment at 900℃,implying a new appropriate method to improve piezoelectric properties. | Jiwen Xu Qingning Li Ling Yang Weidong Zeng Changrong Zhou Changlai Yuan Guohua Chen Guanghui Rao | 2017 | Journal of Materiomics2017，3，2： | 2 |
| 7 | Synthesis and High Electrocatalytic Performance of Hexagram Shaped Gold Particles Having an Open Surface Structure with Kinks显示文摘塑造的金粒子和他们的类似物与性变态由高索引方面围住的六芒星形被与维生素酸(AA ) 减少 HAuCl4 面对成功地综合了 poly (diallyldimethylammonium 氯化物) 在房间温度。由使用电子显微镜学,塑造的 Au 粒子被发现是的六芒星形的表面 { 541 } 飞机,它包含高密度的步和性变态。另外,它被发现那六角形像盾并且在产品在场的其它种粒子是塑造的 Au 粒子组织的六芒星形的类似物,在那,他们有一样的表面结构。以便证实所有准备粒子的表面结构,表面结构 Pb 的敏感 underpotential 免职被执行,并且周期的 voltammetric 侧面根据求婚 { 541 } 表面。最后, Au 六芒星形的结构性质关系被作为探查反应采用 AA 的 electrocatalytic 氧化试验性地分析。金立方体与的 electrocatalytic 反应低索引 { 100 } 方面和金 trioctahedra 与 { 221 } 方面作为参考书被学习。试验性的结果证明六芒星形塑造了 Au 粒子和他们的类似物与暴露 { 541 } 方面在三种金粒子之中举办最高催化的活动,由于纽结原子的高密度。这研究应该激发我们进一步为高索引表面围住的另外的明确的多面的金属 nanocrystals 的准备探索方法。 | Qingning Jiang Zhiyuan Jiang Lei Zhang Haixin Lin Ning Yang Huan Li Deyu Liu Zhaoxiong Xie Zhongqun Tian | 2011 | Nano Research2011，4，6： | 2 |
| 8 | Topological Shape Changes Weaken the Innate Defensive Response to Visual Threat in Mice显示文摘Understanding the primitives of visual perception is a fundamental question in the study of vision.T o address this question,a theory of topology-based functional hierarchy in visual perception has been proposed[1,2].This theory suggests that the extraction of topological properties(TPs)serves as the starting point of object perception.The T P of a figure is the holistic identity which remains constant across various smooth shape-changing transformations of an image[2]. | Yan Huang Lei Li Kun Dong Hongsi Tang Qingning Yang Xianglian Jia Yundan Liao Wenbo Wang Zhen Ren Lin Chen Liping Wang | 2020 | Neuroscience Bulletin2020，36，4： | 2 |
| 9 | Research on Evaluation Model for Secondary Task Driving Safety Based on Driver Eye Movements显示文摘 | Lisheng Jin Huacai Xian Yuying Jiang Qingning Niu Meijiao Xu Dongmei Yang Heiner Bubb | 2014 | Advances in Mechanical Engineering2014，，： | 1 |
| 10 | Effects of stimulated brillouin scattering on gain saturation in discrete Raman fiber amplifiers显示文摘 | CHI R LI Qingning LI Xiangqin | 2004 | Proc of SHE2004，5280，： | 1 |
| 11 | Early identification of acute hypoxia based on brain NADH fluores cence and cerebral blood flow显示文摘Hypoxia is closely related to many diseases and often leads to death.Early detection andidentification of the hypoxia causes may help to promptly determine the right rescue plan andreduce the mortality.We proposed a new multiparametric monitoring method employingmitochondrial reduced nicotinamide adenine dinucleotide(NA DH)fluorescence,regional reflectance,regional cerebral blood flow(CBF),electrocardiography(ECG),and respiration under sixkinds of acute hypoxia in four categories to investigate a correlation bet ween the parametervariances and the hypoxia causes.The variation patterns of the paramet ers were discussed,andthe combination of NADH and CBF may contribute to the identification of the causes of hypoxia. | Hua Shi Nannan Sun Avraham Mayevsky Zhihong Zhang Qingning Luo | 2014 | Journal of Innovative Optical Health Sciences2014，7，2： | 1 |
| 12 | Coupled-local mode theory and study of optical properties of a Gaussian fiber grating 显示文摘 | Qingning Li | 1999 | J Opt Soe Am A1999，16，6： | 1 |
| 13 | The gender- dependent difference of liver GSH antioxidant system in mice and its influence on isoline-induced liver injury显示文摘 | LIANG Qingning SHENG Yuchen JIANG Ping | 2011 | Toxicology2011，280，1： | 1 |
| 14 | Pseudo - dynamic test of the steel frame - Shear wall with prefabricated floor structure 显示文摘 | Chun Hart Qingning Li | 2016 | 20 ( 2 ) 431 - 4452016，20，2： | 1 |
| 15 | Real-time detection of the interaction between anticancer drug daunorubicin and cancer cells by Au-MCNT nanocomposites modified electrodes显示文摘In this study,we have prepared the blending of gold nanoparticles-multiwalled nanotubes (Au-MCNTs) and then applied the new nanocomposites to modify the glassy carbon electrode (GCE) for highly sensitive detection of the interaction between anticancer drug daunorubicin (DNR) and cancer cells. Electrochemical analysis indicates that the Au-MCNT modified GCE shows high sensitivity and could track the real time response of cancer cells under DNR treatments. Therefore,this new nano-interface and Au-MCNT modified electrode could be explored as a rapid,highly sensitive,and convenient real-time detection strategy in cancer related research and would have prospect in other biomedical applications. | LI QingNing WU XiaoJing ZHAO Juan WU ChangYu WANG XueMei | 2011 | Science China Chemistry2011，54，5： | 1 |
| 16 | Syntaphilin显示文摘 | Guifang Lao Volker Scheuss Claudia M Gerwin Qingning Su Sumiko Mochida Jens Rettig Zu-Hang Sheng | 2000 | Neuron2000，，1： | 1 |
| 17 | Lutein and zeaxanthin supplementation reduces photooxidative damage and modulates the expression of inflammation-related genes in retinal pigment epithelial cells显示文摘 | Qingning Bian Shasha Gao Jilin Zhou Jian Qin Allen Taylor Elizabeth J. Johnson Guangwen Tang Janet R. Sparrow Dennis Gierhart Fu Shang | 2012 | Free Radical Biology and Medicine2012，，6： | 1 |
| 18 | Diurnal and Seasonal Courses of Photosynthesis,Transpiration and Water Use Efficiency of Apple and Black Locust Seedlings in Different Soil Water Conditions显示文摘 | HAN Qingn | 1995 | 日本緑化工学会誌1995，21，2： | 1 |
| 19 | A review of parallel and series turbocharging for the diesel engine 显示文摘 | ZHANG Qingning PENNYCOTI' A BRACE C J | 2013 | Journal of Automobile Engineering2013，227，12： | 1 |
| 20 | A Lagrangian relaxation ap- proach for a multi-mode inventory routing problem with transship- ment in crude oil transportation显示文摘 | Qingning Shen Feng Chu Haoxun Chen | 2011 | Computers and Chemical Engineer- ing2011，，10： | 1 |
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