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| 1 | Targeting the tumor stroma in hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC) is one of the most common and deadly cancers worldwide. In ninety percent of the cases it develops as a result of chronic liver damage and it is thus a typical inflammationrelated cancer characterized by the close relation between the tumor microenvironment and tumor cells. The stromal environment consists out of several cell types, including hepatic stellate cells, macrophages and endothelial cells. They are not just active bystanders in the pathogenesis of HCC, but play an important and active role in tumor initiation, progression and metastasis. Furthermore, the tumor itself influences these cells to create a background that is beneficial for sustaining tumor growth. One of the key players is the hepatic stellate cell, which is activated during liver damage and differentiates towards a myofibroblast-like cell. Activated stellate cells are responsible for the deposition of extracellular matrix, increase the production of angiogenic factors and stimulate the recruitment of macrophages. The increase of angiogenic factors(which are secreted by macrophages, tumor cells and activated stellate cells) will induce the formation of new blood vessels, thereby supplying the tumor with more oxygen and nutrients, thus supporting tumor growth and offering a passageway in the circulatory system. In addition, the secretion of chemokines by the tumor cells leads to the recruitment of tumor associated macrophages. These tumor associated macrophages are key actors of cancer-related inflammation, being the main type of inflammatory cells infiltrating the tumor environment and exerting a tumor promoting effect by secreting growth factors, stimulating angiogenesis and influ-encing the activation of stellate cells. This complex interplay between the several cell types involved in liver cancer emphasizes the need for targeting the tumor stroma in HCC patients. | Femke Heindryckx Pär Gerwins | 2015 | World Journal of Hepatology2015，7，2： | 16 |
| 2 | 风力发电机中轴承的过电流问题显示文摘介绍了异步电动机中寄生电流的起因和影响,同时指出了双馈发电机与异步电动机在这方面的区别。讨论了轴承的一般电气性能,并展示了轴承损伤内部机理的最新研究成果。 | Zika Thomas Buschbeck Frank Preisinger Gerwin Martin Groschl 王勇 赵明 | 2008 | 电机与控制应用2008，35，9： | 13 |
| 3 | SKF大型混合陶瓷深沟球轴承——风力发电机的可靠解决方案显示文摘早期的风力发电机轴承失效频繁发生,原因多种多样,在研究应用条件和调查轴承失效的基础上,基本确认了造成轴承失效的根本原因:双馈感应发电机变频驱动所导致的轴承过电流和相应的电腐蚀及润滑、磨损等。对风力发电机轴承早期失效的根本原因进行论述,同时介绍了SKF最新大型混合陶瓷深沟球轴承在减小轴承失效、增加运行可靠性方面的优势及其在风力发电机应用中的解决方案。 | Gerwin Preisinger | 2008 | 电机与控制应用2008，35，12： | 9 |
| 4 | Living in a High Mountain Border Region:the Case of the'Bhotiyas'of the Indo-Chinese Border Region显示文摘This article introduces one of South Asia's most important border regions into academic discourse, namely, the Central Himalayan mountain rim separating India and the Tibetan Autonomous Region (People's Republic of China). What makes this border region so interesting is a tangled interplay of changing environmental, cultural, and political forms to which the local populations constantly have to adapt in order to make a living there. We focused on the so-called 'Bhotiyas' of Uttarakhand, former trans-Himalayan traders whose ethnicity and livelihood was traditionally associated with the Indo-Chinese border that was sealed as a result of the India-China war in 1962. Drawing on the work of borderland scholarship, we identified the key processes and developments that changed the perspective of this area. Competing political aspirations as well as the 'Bhotiyas' countervailing strategies were considered equally important for understanding local livelihoods and identities within the dynamics of a 'high mountain border region'. Through an exemplary analysis of historical differences of power in one 'Bhotiya' valley, we further explored the ways in which shifting socio-spatial constellations are creatively re-interpreted by the borderlanders. | Christoph Bergmann Martin Gerwin Marcus Nüsser William S.Sax | 2008 | Journal of Mountain Science2008，5，3： | 5 |
| 5 | Reconfigurable beam system for non-lineof-sight free-space optical communication显示文摘In this paper,we propose a reconfigurable beam-shaping system to permit energy-efficient non-line-of-sight(NLOS)free-space optical communication.Light is steered around obstacles blocking the direct communication pathway and reaches a receiver after reflecting off of a diffuse surface.A coherent array optical transmitter(CAO-Tx)is used to spatially shape the wavefront of the light incident on a diffuse surface.Wavefront shaping is used to enhance the amount of diffusely reflected light reaching the optical receiver.Synthetic NLOS experiments for a signal reflected over an angular range of 20°are presented.A record-breaking 30-Gbit/s orthogonal frequency-division multiplexing signal is transmitted over a diffused optical wireless link with a>17-dB gain. | Zizheng Cao Xuebing Zhang Gerwin Osnabrugge Juhao Li Ivo M.Vellekoop Antonius M.J.Koonen | 2019 | Light(Science & Applications)2019，8，1： | 2 |
| 6 | Radioembolization of Symptomatic, Unresectable Neuroendocrine Hepatic Metastases Using Yttrium-90 Microspheres显示文摘 | Philipp M. Paprottka Ralf-T. Hoffmann Alexander Haug Wieland H. Sommer Franziska Rae?ler Christoph G. Trumm Gerwin P. Schmidt Nima Ashoori Maximilian F. Reiser Tobias F. Jakobs | 2012 | CardioVascular and Interventional Radiology2012，，2： | 2 |
| 7 | 鹿特丹国际电影节专访显示文摘李:您能否简要描述一下鹿特丹电影节是个什么样的电影节? | 李镇(采访人) Gerwin Tamsma(受访人) | 2008 | 当代电影2008，，3： | 2 |
| 8 | Function of fibroblast growth factors and vascular endothelial growth factors and their receptors in angiogenesis显示文摘 | Gerwins P Skoldenberg E Claesson-Welsh L | 2004 | Critical Reviews in Oncoy/Hematol2004，34，： | 1 |
| 9 | Function of fibroblast growth factor and VEGF and their receptors in angiogenesis显示文摘 | Skoidenberg E Claesson Welsh L | 2000 | Crit Rev Oncol Hematol2000，34，3： | 1 |
| 10 | Activation of mitogen-activated protein kinases in experimental cerebral ischemia显示文摘 | Lennmyr F Karlsson S Gerwins P | 2002 | Acta Neurol Scand2002，106，6： | 1 |
| 11 | Alternative operative exposures of the posterior aspect of the humeral diaphysis with reference to the radial nerve 显示文摘 | Gerwin M Hotchkiss RN Weiland AJ | 1996 | J Bone Joint Surg Am1996，78，： | 1 |
| 12 | Histopathology atlas of animal model systems - overview of guiding principles 显示文摘 | Aigner T Cook J L Gerwin N | 2010 | Osteoarthritis Cartilage2010，18，10： | 1 |
| 13 | Flexible active-matrix displays and shift registers based on solution-processed organic transistors显示文摘 | Gerlinck Gerwin H Huitema Edzer A | | 0，，02： | 1 |
| 14 | The Wadsworth BCI Research and Development Program: At Home with BCI 显示文摘 | Theresa M Vaughan Dennis J McFarland Gerwin Schalk | 2006 | IEEE Transactions on Neural Systems and Rehabilitation Engineering2006，14，2： | 1 |
| 15 | Manufacturing flexibility: A strategic perspective 显示文摘 | Gerwin D | 1993 | Management Science1993，39，4： | 1 |
| 16 | A new mechanism of blood vessel growth-hope for new treatment strategies显示文摘 | Kilarski WW Gerwins P | 2009 | Discov Med2009，8，： | 1 |
| 17 | Activa-tion of mitogen activated Protein kinases in experi-mental cerebral ischemia 显示文摘 | Lennmyr F Karlsson S Gerwins P | 2002 | Acta Neurol Scand2002，106，6： | 1 |
| 18 | Alternative operative exposures of the posterior aspect of the humeral diaphysis with reference to the radial nerve显示文摘 | Gerwin M Hotchkiss RN Weiland AJ | | 0，，11： | 1 |
| 19 | Activation of mitogen activated Protein kinases in experimental cere- bral ischemia显示文摘 | Lennmyr F Karlsson S Gerwins P | 2002 | Acta Neurol Scand2002，106，6： | 1 |
| 20 | Histopathology atlas of animal model systems-overview of guiding principles 显示文摘 | Aigner T Cook J L Gerwin N | 2010 | Osteoarthritis Cartilage2010，18，3： | 1 |
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