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| 1 | Effects of probiotic bacteria on gastrointestinal motility in guinea-pig isolated tissue显示文摘AIM: To evaluate the intestinal motility changes evoked by 8 bacterial strains belonging to Bifidobacterium , Lactobacillus and Streptococcus genera within the probiotic preparation VSL#3. METHODS: Ileum and proximal colon segments isolated from guinea-pigs were used as a study model. Entire cells and cell fractions (cell debris, cell wall fraction, cytoplasmatic fraction, proteinaceous and non- proteinaceous cytoplasmatic components) of VSL#3 strains and, as controls, Escherichia coli, Salmonella aboni and Bacillus licheniformis were tested in this in vitro model. RESULTS: Among the bacterial cell fractions tested, only the cytoplasmatic fraction modified intestinal motility. Lactobacillus strains stimulated the contraction of ileum segment, whereas all probiotic strains tested induced proximal colon relaxation response. The non-proteinaceous cytoplasmatic components were responsible for the colon relaxation. CONCLUSION: The results obtained in this study suggest that the proximal colon relaxation activity showed by the probiotic bacteria could be one of the possible mechanisms of action by which probiotics exert their positive effects in regulating intestinal motility. | Matteo Massi Pierfranco Ioan Roberta Budriesi Alberto Chiarini Beatrice Vitali Karen M Lammers Paolo Gionchetti Massimo Campieri Anthony Lembo Patrizia Brigidi | 2006 | World Journal of Gastroenterology2006，12，37： | 3 |
| 2 | Eye reflux:an ocular extraesophageal manifestation of gastric reflux显示文摘AIM: To suspect laryngopharyngeal reflux(LPR) in patients with ocular surface disease(OSD). METHODS: The present study evaluated a group of subjects with OSD assessing the Ocular Surface Disease Index(OSDI) and the Reflux Symptom Index(RSI) to detect patients with suspected LPR and define a possible relationship between tests.RESULTS: Two hundred and ninety subjects(175 females, mean age: 60.41±15.68y) were consecutively visited at ophthalmologist offices. One hundred and one(34%) patients had pathological RSI(>13) and consequently a suspected LPR.CONCLUSION: The current study shows that suspected LPR may be common(34%) in patients with OSD and a suspected LPR may be considered in OSD patients when RSI score is >13 and OSDI score is >42. | Danilo Mazzacane Valerio Damiani Michela Silvestri Giorgio Ciprandi Pierfranco Marino | 2018 | International Journal of Ophthalmology(English edition)2018，11，9： | 2 |
| 3 | Two-millimeter dermoscopically detected excision margins in the treatment of basal cell carcinoma:an assessment of radicality and recurrence显示文摘Sir,Eighty-five percent of all basal cell carcinomas(BCCs)are located in the head and neck,with a markedly increased incidence after the age of 40 years.Complete extirpation in the early phase allows to limit skin excision and facilitates reconstruction,reducing consequent scarring.In the medical literature,it is reported that appropriate excision margins should be included between 3 and 10 mm,based on location,dimensions,margins and histology.[1]BCC margins are defined by the discontinuation of well-known dermoscopic features along the skin lesion borders,so separating cancer from healthy skin.[2]The authors conducted a study to assess the effectiveness of preoperative dermoscopic evaluation of BCC peripheral margins,in order to achieve complete excision. | Pierfranco Simone Carlo Carusi Riccardo Iannuzzi Paolo Persichetti | 2016 | Plastic and Aesthetic Research2016，3，1： | 1 |
| 4 | Bevacizumab and osteonecrosis of the jaw: incidence and association with bisphosphonate therapy in three large prospective trials in advanced breast cancer显示文摘 | Valentina Guarneri David Miles Nicholas Robert Véronique Diéras John Glaspy Ian Smith Christoph Thomssen Laura Biganzoli Tanya Taran PierFranco Conte | 2010 | Breast Cancer Research and Treatment2010，，1： | 1 |
| 5 | Multicentric, Randomized Phase III Trial of Two Different Adjuvant Chemotherapy Regimens plus Three Versus Twelve Months of Trastuzumab in Patients with HER2-Positive Breast Cancer (Short-HER Trial; NCT00629278)显示文摘 | Valentina Guarneri Antonio Frassoldati Paolo Bruzzi Roberto D’Amico Maurizio Belfiglio Annamaria Molino Oscar Bertetto Stefano Cascinu Francesco Cognetti Angelo Di Leo Paolo Pronzato Lucio Crinó Biagio Agostara PierFranco Conte | 2008 | Clinical Breast Cancer2008，，5： | 1 |
| 6 | Mitochondrial Dysfunction and α -Synuclein Synaptic Pathology in Parkinson’s Disease: Who’s on First?显示文摘 | Michela Zaltieri Francesca Longhena Marina Pizzi Cristina Missale PierFranco Spano Arianna Bellucci Patrick Lewis | 2015 | Parkinson’s Disease2015，，： | 1 |
| 7 | Analysis of One-Dimensional Modelling for Flood Routing in Compound Channels显示文摘 | Pierfranco Costabile Francesco Macchione | 2012 | Water Resources Management2012，，5： | 1 |
| 8 | Prevention of neuron and oligodendrocyte degeneration by interleukin-6 (IL-6) and IL-6 receptor/IL-6 fusion protein in organotypic hippocampal slices显示文摘 | Marina Pizzi Ilenia Sarnico Flora Boroni Marina Benarese Michel Dreano Gianni Garotta Alessandra Valerio PierFranco Spano | 2003 | Molecular and Cellular Neuroscience2003，，2： | 1 |
| 9 | Concentration, distribution, and translocation of mercury and methylmercury in mine-waste, sediment, soil, water, and fish collected near the Abbadia San Salvatore mercury mine, Monte Amiata district, Italy显示文摘 | Valentina Rimondi John E. Gray Pilario Costagliola Orlando Vaselli Pierfranco Lattanzi | 2011 | Science of the Total Environment2011，，： | 1 |
| 10 | Distinct roles of diverse nuclear factor-KB complexes in neuropathological mechanisms 显示文摘 | Marina Pizzi PierFranco Spano | 2006 | European Journal of Pharmacology2006，545，1： | 1 |
| 11 | A storm event watershed model for surface runoff based on 2D fully dy- namic wave equations 显示文摘 | Pierfranco CostabiLe Carmelina Costanzo Francesco Macchione | 2013 | Hydrological Processes2013，27，4： | 1 |
| 12 | Primary Angioplasty with Manual Thrombectomy Alone as a Therapeutic Strategy in a Patient with Acute Myocardial Infarction and Severe Anemia显示文摘 | Giuseppe Talanas Giuseppina Fiore pierFranco Terrosu | 2016 | HellenicJ Cardiol2016，57，1： | 1 |
| 13 | Isolation, Characterization, and Transduction of Endometrial Decidual Tissue Multipotent Mesenchymal Stromal/Stem Cells from Menstrual Blood显示文摘 | Filippo Rossignoli Anna Caselli Giulia Grisendi Serena Piccinno Jorge S. Burns Alba Murgia Elena Veronesi Pietro Loschi Cristina Masini Pierfranco Conte Paolo Paolucci Edwin M. Horwiz Massimo Dominici Thomas Skutella | 2013 | BioMed Research International2013，，： | 1 |
| 14 | Usefulness of Three‐Dimensional Transthoracic Echocardiography in Particular Clinical Settings: A Case of Aorto‐Cavitary Fistula in Periprosthetic Aortic Valve Abscess显示文摘 | Stefano Maffè Franco Zenone Pierfranco Dellavesa Paola Paffoni Anna Maria Paino Fabiana Signorotti Lorenzo Cucchi Nicolò Franchetti Pardo Umberto Parravicini | 2012 | Echocardiography2012，，6： | 1 |
| 15 | Safety of intrabenous and oral bisphosphonates and compliance with dosing regimens显示文摘 | Pierfranco Conte Valentina Guarneri | 2004 | The Oncologist2004，9，4： | 1 |
| 16 | Digital Photography in Plastic Surgery: How to Achieve Reasonable Standardization Outside a Photographic Studio 显示文摘 | Paolo Persichetti Pierfranco Simone Marika Langella | 2007 | Aesth Plast Surg2007，31，： | 1 |
| 17 | Acetylcysteine and contrast agent-associated nephrotoxicity显示文摘 | Carlo Briguori Fiore Manganelli Pierfranco Scarpato Pietro Paolo Elia Bruno Golia Guido Riviezzo Stefano Lepore Mariateresa Librera Bruno Villari Antonio Colombo Bruno Ricciardelli | 2002 | Journal of the American College of Cardiology2002，，2： | 1 |
| 18 | Under the Skin. Intangible Components as the Basic Realities of Contemporary Post-bureaucratic Organizations: A Sociological Perspective显示文摘 | Pierfranco Malizia | 2012 | Journal of Sociology Study2012，2，8： | 0 |
| 19 | 意大利政府对残疾人的优惠政策及工法架构(英文)显示文摘The most important reference in Italian legislation concerning interventions in favour of people with disabilities came about with Law 104 from February 5th 1992 in which the most important rights for disabled people were established. This law led to a new vision,the person with disabilities is no longer seen only a subject needing help but as a person who has the right to live his life in the best possible way that his condition allows him to and thus,it is society's duty and that of the Government,to do everything possible to remove invalidating causes,to promote a disabled person's autonomy and to realise his best social integration possible. To implement what is foreseen by this law it was necessary to activate different important interventions,two of which are very significant:the realisation of Guidelines from the Ministry of Health on rehabilitation activities in which the aims are defined on how rehabilitation should be implemented and how it should be organised on a national level and at a community level. Law 68 from March 12th 1999 decreed the full rights of people with disability to be integrated into the workplace. In the article we will also report some significant data concerning the results of the applications of the law. | Maria Teresa Agati Alessandro Giustini Alessandro Solipaca Pierfranco Linari David Fletzer Elisabetta Del Bufalo | 2011 | 中国康复理论与实践2011，17，10： | 0 |
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