|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Protective effect of Nigella sativa oil against binge ethanolinduced oxidative stress and liver injury in rats显示文摘AIM: Nigella sativa L.(Ranunculaceae) is considered as a therapeutic plant-based medicine for liver damage. In this study, the aim was to study the effect of Nigella sativa oil(NSO) pretreatment on ethanol-induced hepatotoxicity in rats. METHOD: Rats were given Nigella sativa oil at doses of 2.5 and 5.0 mL·kg-1, orally for 3 weeks, followed by oral ethanol(EtOH) administration(5 g·kg-1) every 12 h three times(binge model). RESULTS: Binge ethanol application caused significant increases in plasma transaminase activities and hepatic triglyceride and malondialdehyde(MDA) levels. It decreased hepatic glutathione(GSH) levels, but did not change vitamins E and vitamin C levels and antioxidant enzyme activities. NSO(5.0 mL·kg-1) pretreatment significantly decreased plasma transaminase activities, hepatic MDA, and triglyceride levels together with amelioration in hepatic histopathological findings. CONCLUSION: NSO pretreatment may be effective in protecting oxidative stress-induced hepatotoxicity after ethanol administration. | Seval Develi Betül Evran Esra Betül Kalaz Necla Koak-Toker Gül zdemirler Erata | 2014 | Chinese Journal of Natural Medicines2014，12，7： | 4 |
| 2 | Peroxynitrite induced decrease in Na^+, K^+-ATPase activity is restored by taurine显示文摘AIM: Peroxynitrite (ONOO-) is a powerful oxidant shown to damage membranes. In the present study, the effect of taurine on changes of liver plasma membrane Na+, K+-ATPase induced by ONOO- was investigated. METHODS: Liver plasma membrane was exposed toONOO-with or without taurine. Na+, K+-ATPase activity and lipid peroxidation as thiobarbituric acid reactive substances (TBARS) levels were measured.RESULTS: Different concentrations of ONOO- (100, 200,500, and 1 000 μmol/L) were found to decrease liver plasma membrane Na+, K+-ATPase activity significantly. The depletion of enzyme activity was not concentration dependent. Effects of different concentrations of taurine on liver plasma membrane Na+, K+-ATPase activity were also measured. Taurine did not cause any increase in enzyme activity. When plasma membranes were treated with 200 μmol/L ONOO- with different concentrations of taurine, a restoring effect of taurine on enzyme activity was observed. TBARS levels were also measured and taurine was found to decrease the elevated values. CONCLUSION: Taurine is observed to act as an antioxidant of ONOO-to decrease lipid peroxidation and thus affect liver plasma membrane Na+, K+-ATPase by restoring its activity. | Necla Kocak-Toker Murat Giris Feti Tülübas Müjdat Uysal Gülcin Aykac-Toker | 2005 | World Journal of Gastroenterology2005，11，23： | 2 |
| 3 | Adsorption of Zinc(II) on diatomite and manganese-oxide-modified diatomite: A kinetic and equilibrium study显示文摘 | Necla Caliskan Ali Riza Kul Salih Alkan Eda Gokirmak Sogut ?hsan Alacabey | 2011 | Journal of Hazardous Materials2011，，： | 1 |
| 4 | p wave dispersion in hypertensive patients with paroxysmal atrial fibrillation显示文摘 | Necla ozer Kudret Aytemir Enver Atalar | 2000 | PACE2000，23，： | 1 |
| 5 | Classification of impacted blueberries during storage using an electronic nose显示文摘 | NECLA D ANTONIO C STEVEN A | | 0，，： | 1 |
| 6 | QT interval dispersion changes according to the vessel involved during percutaneous coronary angioplasty显示文摘 | Kilic H Atalar E Necla O | 2007 | J Natl Med Assoc2007，，： | 1 |
| 7 | An Overview of Intuitionistic Fuzzy Suprat-Opological Spaces显示文摘 | Necla Turanh | 2003 | Hacettepe Journal of Mathematics and Statistics2003，32，： | 1 |
| 8 | An overview of intuitionistic fuzzy supra topological spaces显示文摘 | Necla Turanh | 2003 | Hacettepe Journal of Mathematics and Statistics2003，32，： | 1 |
| 9 | Leptin and resistin levels and their relationships with glucose metabolism in children with chronic renal insufficiency and undergoing dialysis显示文摘 | Necla B Aysun B Ozan O | 2006 | Nephrol2006，11，： | 1 |
| 10 | WSNSec: A scalable data link layer security pro- tocol for WSNs 显示文摘 | Necla Bandirmali | 2012 | Ad Hoc Networks2012，10，1： | 1 |
| 11 | Prediction of Torque and Specific Fuel Consumption of a Gasoline Engine by Using Artificial Neural Networks显示文摘 | Necla Kara Togun Sedat Bavsec | | 0，，： | 1 |
| 12 | Prediction of torque and specific fuel consumption of a gasoline engine by using artificial neural networks显示文摘 | Necla Kara Togun Sedat Baysec | 2009 | Applied Energy2009，，1： | 1 |
| 13 | Brucella: A Cause of Peripheral Neuropathy显示文摘 | Kutlu Gulnihal Ertem Gunay Tuncer Coskun Ozlem Ergun Ufuk Gomceli Yasemin B Tulek Necla Inan Levent Ertugrul | 2008 | European Neurology2008，，1： | 1 |
| 14 | Unusual Clinical Presentations of Brucellosis显示文摘 | Cigdem Ataman Hatipoglu Arzu Yetkin Gunay Tuncer Ertem Necla Tulek | 2004 | Scandinavian Journal of Infectious Diseases2004，，9： | 1 |
| 15 | Is thioredoxin reductase involved in the defense againsi DNA fragmentation in varicocele?显示文摘 | Gill Ozdemirler Erata Canan Kfiqiikgergin Giilsan Aktan Ates KadoOuI Miijdat Uysal Necla Kocak-Toker | 2013 | Asian Journal of Andrology2013，15，4： | 1 |
| 16 | The inhibition effect of some pyrimidine derivatives on austenitic stainless steel in acidic media显示文摘 | Necla Caliskan Esvet Akbas | 2010 | Materials Chemistry and Physics2010，，3： | 1 |
| 17 | QT interval dispersion changes according to the vessel involved during pereutaneous coronary angioplasty 显示文摘 | KILIC H ATALAR E NECLA O | 2007 | J Natl Med Assoe2007，99，8： | 1 |
| 18 | Pulmonary Function Tests and High-Resolution CT in the Detection of Pulmonary Involvement in Inflammatory Bowel Disease显示文摘 | Necla Songür Yldran Songür Meri? Tüzün Ibrahim Do?an Dilek Tüzün Arzu Ensari Baki Hekimoglu | 2003 | Journal of Clinical Gastroenterology2003，，4： | 1 |
| 19 | Adsorption of Zinc(II) on diatomite and manganese - oxide - modified diatomite: A kinetic and e- quilibrium study 显示文摘 | Necla Caliskan Ali Riza Kul Salih Alkan Eda Gokirmak Sogut I ' hsan Alacabey | 2011 | Journal of Hazardous Materials2011，193，： | 1 |
| 20 | Nonlinear modeling and identification of a spark ignition engine torque显示文摘 | NECLA T SEDATBAYSEC TOLGAYKARA | 2012 | Mechanical Systems and Signal Processing2012，26，29： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员