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| 1 | Protective effects of intravenous anesthetics on kidney tissue in obstructive jaundice显示文摘AIM:To evaluate the protective effects on kidney tissue of frequently used intravenous anesthetics(ketamine,propofol,thiopental,and fentanyl)in rats with obstructive jaundice.METHODS:There is an increased incidence of postoperative acute renal failure in patients with obstructive jaundice.Thirty-two Wistar-albino rats were randomly divided into four equal groups.Laparatomy was performed on each animal in the four groups and common bile ducts were ligated and severed on day 0.After 7 d,laparotomy was again performed using ketamine,propofol,thiopental,or fentanyl anesthesia whose antioxidative properties are well known in oxidative stress in a rat liver model of obstructive jaundice.After 2 h,the rats were sacrificed.Renal tissue specimens were analyzed for catalase,superoxide dismutase and malondialdehyde enzymes activities.All values are expressed as the mean±SD.P values less than 0.05 were considered statistically significant.RESULTS:All animals survived without complications until the end of the study.Enlargement in the bile duct and obstructive jaundice were observed in all rats.Catalase was found to be significantly lower in the fentanyl group than in the ketamine(P=0.039),propofol(P=0.012),and thiopental(P=0.001)groups.Superoxide dismutase activities were similar in all groups(P>0.05).Malondialdehyde was found to be significantly lower in the ketamine group than in the propofol(P=0.028),thiopental(P=0.002)and fentanyl(P=0.005)groups.Malondialdehyde was also lower in the fentanyl group than in the thiopental group(P=0.001).The results showed that obstructive jaundice sensitizes renal tissue to damage under the different anesthetics.CONCLUSION:Among the agents tested,ketamine and propofol generated the least amount of oxidative stres on renal tissues in this rat model of obstructive jaundice created by common bile duct ligation.The importance of free radical injury in renal tissue in obstructive jaundice under different intravenous anesthetics during hepatobiliary and liver transplant surgery should be considered for prevention of postoperative acute renal failure. | Sinan Hatipoglu Huseyin Yildiz Ertan Bulbuloglu Ismail Coskuner Ergul Belge Kurutas Filiz Hatipoglu Harun Ciralik Mehmet Sait Berhuni | 2014 | World Journal of Gastroenterology2014,20,12: | 9 |
| 2 | Acute right lower abdominal pain in women of reproductive age:Clinical clues显示文摘AIM:To study possible gynecological organ pathologies in the differential diagnosis of acute right lower abdominal pain in patients of reproductive age.METHODS:Following Clinical Trials Ethical Committee approval,the retrospective data consisting of physical examination and laboratory findings in 290 patients with sudden onset right lower abdominal pain who used the emergency surgery service between April2009 and September 2013,and underwent surgery and general anesthesia with a diagnosis of acute appendicitis were collated.RESULTS:Total data on 290 patients were obtained.Two hundred and twenty-four(77.2%)patients had acute appendicitis,whereas 29(10%)had perforated appendicitis and 37(12.8%)had gynecological organ pathologies.Of the latter,21(7.2%)had ovarian cyst rupture,12(4.2%)had corpus hemorrhagicum cyst rupture and 4(1.4%)had adnexal torsion.Defense,Rovsing’s sign,increased body temperature and increased leukocyte count were found to be statistically significant in the differential diagnosis of acute appendicitis and gynecological organ pathologies.CONCLUSION:Gynecological pathologies in women of reproductive age are misleading in the diagnosis of acute appendicitis. | Sinan Hatipoglu Filiz Hatipoglu Ruslan Abdullayev | 2014 | World Journal of Gastroenterology2014,20,14: | 8 |
| 3 | Effect of laparoscopic abdominal surgery on splanchnic circulation: Historical developments显示文摘With the developments in medical technology and increased surgical experience,advanced laparoscopic surgical procedures are performed successfully.Laproscopic abdominal surgery is one of the best examples of advanced laparoscopic surgery(LS).Today,laparoscopic abdominal surgery in general surgery clinics is the basis of all abdominal surgical interventions.Laparo scopica bdomina l surgery is associated with systemic and splanchnic hemodynamic alterations.Inadequate splanchnic perfusion in critically ill patients is associated with increased morbidity and mortality.The underlying pathophysiological mechanisms are still not well understood.With experience and with an increase inthe number and diversity of the resulting data,the pathophysiology of laparoscopic abdominal surgery is now better understood.The normal physiology and pathophysiology of local and systemic effects of laparoscopic abdominal surgery is extremely important for safe and effective LS.Future research projects should focus on the interplay between the physiological regulatory mechanisms in the splanchnic circulation(SC),organs,and diseases.In this review,we discuss the effects of laparoscopic abdominal surgery on the SC. | Sinan Hatipoglu Sami Akbulut Filiz Hatipoglu Ruslan Abdullayev | 2014 | World Journal of Gastroenterology2014,20,48: | 5 |
| 4 | Pancreatic extragastrointestinal stromal tumor:A case report and comprehensive literature review显示文摘AIM: To provide an overview of the literature on pan-creatic extragastrointestinal stromal tumors(EGISTs).METHODS: We report a case of pancreatic EGIST and review published studies on pancreatic EGIST ac-cessed via the PubMed, MEDlInE, Google Scholar, and Google databases. The keywords used were 'pancreas and GIST', 'pancreas and extra GIST', 'pancreas and gastrointestinal stromal tumor', and 'pancreas and ex-tragastrointestinal stromal tumor'. literature reviews and/or duplicate studies were excluded. The search included articles published in the English language be-tween January 1, 2000 and May 15, 2014.RESULTS: From our literature survey, 30 manuscripts on pancreatic EGISTs were considered, of which 27met the search criteria and three were excluded. The studies involved 30 patients(15 men, 15 women) with a mean age of 55.3 ± 14.3 years(range 30-84 years). The mean age of the male patients was 50.8 ± 13.7 years(range 30-84 years); that of the female patients was 59.9 ± 13.3 years(range 38-81 years). Tumor dimensions were obtained for 28 cases(mean 114.4 ± 78.6 mm; range 20-350 mm). Tumors were diagnosed incidentally in 23.3% of patients; abdominal discomfort and weight loss were the major complaints in symp-tomatic patients. Risk of aggressive behavior according to Fletcher criteria was determined in 25 of 30 patients(68%: high risk, 28%: intermediate risk, 4%: low risk). Histopathological examination revealed the presence of spindle cells in 96.1% of cases; CD117 and CD34 were present immunohistochemically in 96.6% and 84% of patients, respectively. The most common surgical pro-cedures were distal pancreatectomy with splenectomy(n = 9) and pancreaticoduodenectomy(n = 7). The to-tal follow-up period for the 28 patients ranged from 3-66 mo, during which locoregional or distant metastases were diagnosed in six patients and two patients died.CONCLUSION: Studies on EGISTs have only been published in the last decade. The lack of studies with large patient cohorts and long-term follow-up limits evidence-based commentary. In theory, each case should be assessed individually and further genetic and immunohistochemical studies are needed. | Sami Akbulut Rdvan Yavuz Emrah Otan Sinan Hatipoglu | 2014 | World Journal of Gastrointestinal Surgery2014,6,9: | 4 |
| 5 | Agenesis of the dorsal pancreas显示文摘Developmental anomalies of the pancreas have been reported but dorsal pancreatic agenesis is an extremely rare entity. We report an asymptomatic 62-year-old woman with complete agenesis of the dorsal pancreas. Abdominal computed tomography (CT) revealed a normal pancreatic head, but pancreatic body and tail were not visualized. Magnetic resonance imaging (MRI) findings were similar to CT. At magnetic resonance cholangiopancreatography (MRCP), the major pancreatic duct was short and the dorsal pancreatic duct was not visualized. The final diagnosis was dorsal pancreatic agenesis. | Lale Pasaoglu Murat Vural Hatice Gul Hatipoglu Gokce Tereklioglu Suha Koparal | 2008 | World Journal of Gastroenterology2008,14,18: | 3 |
| 6 | Effectiveness and safety of ureteroscopy in pregnant women: a comparative study显示文摘 | Yasar Bozkurt Haluk Soylemez Murat Atar Ahmet Ali Sancaktutar Necmettin Penbegul Nam?k Kemal Hatipoglu Mehmet Nuri Bodakc? Mehmet S?dd?k Evsen | 2013 | Urolithiasis2013,,1: | 2 |
| 7 | Photocatalytic degradation of 4-nitrophenol in aqueous TiO2 suspensions: Theoretical prediction of the intermediates 显示文摘 | San N Hatipoglu A | 2002 | J Photochem Photobiol A2002,146,: | 1 |
| 8 | Piperacillin/tazobactam-in- duced neutropenia, thrombocytopenia, and fever during treatment of a diabetic foot infection 显示文摘 | Uzun G Onem Y Hatipoglu M | 2013 | Scand J Infect Dis2013,45,1: | 1 |
| 9 | Texture Classification Using Dual-tree Complex Wavelet Transform显示文摘 | Hatipoglu S Mitra S K Kingsbury N | 1999 | Image Processing and Its Applications1999,1,1315: | 1 |
| 10 | The relationship between bifidobaeteria and allergic asthma and/or al- lergic dermatitis : A prospective study of 0-3 years-old children in Turkey显示文摘 | Hatice Kubra Akay Hrisi Bahar Tokman Nevin Hatipoglu | 2014 | Anaerobe2014,,: | 1 |
| 11 | Changes in brain and lung angiotensin converting enzyme activity in various shocks 显示文摘 | Koyuncuoglu H Gungor M Hatipoglu I | 1984 | Pharmacol Res Commun1984,16,5: | 1 |
| 12 | Inflammation and obstructive sleep apnea syndrome pathogenesis: a working hypothesis显示文摘 | Hatipoglu U Rubinstein I | 2003 | Respiration2003,70,6: | 1 |
| 13 | Inflammation and obstructive sleep apnea syndrome pathogenesis:a working hypothesis 显示文摘 | Hatipoglu U Rubinstein I | 2004 | Respiration2004,70,6: | 1 |
| 14 | Evalua- tion of anxiolytic effect and withdrawal anxiety in chro- nic intermittent diazepam treatment in rats 显示文摘 | Acikmese B Haznedar S Hatipoglu I | 2012 | Behav Pharmacol2012,23,2: | 1 |
| 15 | Hepatitis B virus e antigen (HBeAg) may have a negative effect on dendritic cell generation显示文摘 | Ibrahim Hatipoglu Duygu Ercan Ceyda Acilan Aynur Basalp Deniz Durali Ahmet Tarik Baykal | 2014 | Immunobiology2014,,: | 1 |
| 16 | Pedunculated solitary fibrous tumors arising from the pleura显示文摘 | Poyraz A Kilic D Hatipoglu A | 2006 | Monaldi Arch Chest Dis2006,65,3: | 1 |
| 17 | Islet transplantation for brittlc type 1 diabetes:the UIC protocol显示文摘 | Gangemia A Salehi P Hatipoglu B | | 0,,: | 1 |
| 18 | Steering and Lane Change: A Working System 显示文摘 | CEM Hatipoglu KEITH Redmill UMIT Ozguner | 1998 | 1EEE1998,,: | 1 |
| 19 | Automated lane change controller design显示文摘 | HATIPOGLU C OZGUNER U REDMILL K A | 2003 | IEEE Transactions on Intelligent Transportation Systems2003,4,1: | 1 |
| 20 | Concha bullosa types:their relationship with sinusitis,ostiomeatal and frontal recess disease显示文摘 | Hatipoglu H G Cetin M A Yuksel E | 2005 | Diagn Interv Radiol2005,11,3: | 1 |