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| 1 | Immobilized thrombin on X-ray radiopaque polyvinyl alcohol/chitosan embolic microspheres for precise localization and topical blood coagulation显示文摘Trans-catheter arterial embolization(TAE)plays an important role in treating various diseases.The available embolic agents lack X-ray visibility and do not prevent the reflux phenomenon,thus hindering their application for TAE therapy.Herein,we aim to develop a multifunctional embolic agent that combines the X-ray radiopacity with local procoagulant activity.The barium sulfate nanoparticles(BaSO4 NPs)were synthesized and loaded into the polyvinyl alcohol/chitosan(PVA/CS)to prepare the radiopaque BaSO4/PVA/CS microspheres(MS).Thereafter,thrombin was immobilized onto the BaSO4/PVA/CS MS to obtain the thrombin@BaSO4/PVA/CS MS.The prepared BaSO4/PVA/CS MS were highly spherical with diameters ranging from 100 to 300μm.In vitro CT imaging showed increased X-ray visibility of BaSO4/PVA/CS MS with the increased content of BaSO4 NPs in the PVA/CS MS.The biocompatibility assessments demonstrated that the MS were non-cytotoxic and possessed permissible hemolysis rate.The biofunctionalized thrombin@BaSO4/PVA/CS MS showed improved hemostatic capacity and facilitated hemostasis in vitro.Additionally,in vivo study performed on a rabbit ear embolization model confirmed the excellent X-ray radiopaque stability of the BaSO4/PVA/CS MS.Moreover,both the BaSO4/PVA/CS and thrombin@BaSO4/PVA/CS MS achieved superior embolization effects with progressive ischemic necrosis on the ear tissue and induced prominent ultrastructural changes in the endothelial cells.The findings of this study suggest that the developed MS could act as a radiopaque and hemostatic embolic agent to improve the embolization efficiency. | Xiaohong Li Xiongfa Ji Kun Chen Muhammad Wajid Ullah Basen Li Jiameng Cao Lin Xiao Jun Xiao Guang Yang | 2021 | Bioactive Materials2021，6，7： | 6 |
| 2 | Characteristic spectral studies and in vitro antifungal activity of some Schiff bases and their organotin (Ⅳ) complexes显示文摘The synthesis and in vitro antifungal activity of some Schiff bases and their Sn (Ⅳ) complexes has been tested against plant pathogenic fungi and it is found that they possess excellent fungicidal activity. On the basis of ^1H-, ^13C-,^119Sn NMR-, ^119Sn Mǒssbauer, IR and Elemental analysis the tetrahedral geometry is proposed for the synthesized compounds. | Wajid Rehman Musa Kaleem Baloch Bakhtiar Muhammad Amin Badshah Khalid M.Khan | 2004 | Chinese Science Bulletin2004，49，2： | 3 |
| 3 | Synthesis of yttrium and cerium doped ZnO nanoparticles as highly inexpensive and stable photocatalysts for hydrogen evolution显示文摘Yttrium and cerium co-doped ZnO nanoparticles were synthesized by combustion route and characterized using X-ray diffraction(XRD),scanning electron microscopy(SEM),Brunauer-Emmett-Teller(BET),energy dispersive spectroscopy(EDS),X-ray photoelectron spectroscopy(XPS),UV-visible diffuse reflectance spectroscopy(UV-vis DRS),photoluminescence(PL)and electrochemical impedance spectroscopy(EIS)techniques.The introduction of yttrium ions has efficiently increased the relative percentage of Ce^(3+)ions in ZnO.Yttrium and cerium co-doped ZnO shows efficient photo activity for hydrogen evolution(10.61 mmol/((g·h))higher than previously reported optimal value for rare earth codoped ZnO photocatalysts.This remarkably increased hydrogen evolution can be ascribed to the synergy between electronic anchoring effect of Y^(3+)/Y^(2+)and Ce^(4+)/Ce^(3+)redox couples.This report presents new idea for the synthesis of efficient photocatalyst using economical route and ion anchoring effect.The hydrogen evolution was also tested using Na_(2)S and Na_(2)SO_(3)as electron donors under visible light illumination.The synthesized photocatalysts also exhibit high stability. | Irshad Ahmad Muhammad Shoaib Akhtar Mian Faisal Manzoor Muhammad Wajid Muhammad Noman Ejaz Ahmed Mukhtar Ahmad Waheed Qamar Khan Anwar M.Rana | 2021 | Journal of Rare Earths2021，39，4： | 2 |
| 4 | Hollow fiber-based liquid phase microextraction followed by analytical instrumental techniques for quantitative analysis of heavy metal ions and pharmaceuticals显示文摘Hollow-fiber liquid-phase microextraction(HF-LPME)and electromembrane extraction(EME)are miniaturized extraction techniques,and have been coupled with various analytical instruments for trace analysis of heavy metals,drugs and other organic compounds,in recent years.HF-LPME and EME provide high selectivity,efficient sample cleanup and enrichment,and reduce the consumption of organic sol-vents to a few micro-liters per sample.HF-LPME and EME are compatible with different analytical in-struments for chromatography,electrophoresis,atomic spectroscopy,mass spectrometry,and electrochemical detection.HF-LPME and EME have gained significant popularity during the recent years.This review focuses on hollow fiber based techniques(especially HF-LPME and EME)of heavy metals and pharmaceuticals(published 2017 to May 2019),and their combinations with atomic spectroscopy,UV-VIS spectrophotometry,high performance liquid chromatography,gas chromatography,capillary elec-trophoresis,and voltammetry. | Wajid Ali Khan Muhammad Balal Arain Yadollah Yamini Nasrullah Shah Tasneem Gul Kazi Stig Pedersen-Bjergaard Mohammad Tajik | 2020 | Journal of Pharmaceutical Analysis2020，10，2： | 2 |
| 5 | Development of bis-thiobarbiturates as successful urease inhibitors and their molecular modeling studies显示文摘Bis-thiobarbiturate derivatives 1–15 have been synthesized, characterized by1 HNMR and EI-MS and screened for urease inhibition. All compounds showed various degree of urease inhibitory activity with IC_(50) values ranging 7.45 0.12 74.24 0.81 mmol/L while the standard thiourea behaved normally(IC_(50) = 21.10 0.12). Compounds 1(IC_(50) = 7.45 0.12 μmol/L), 9(IC_(50) = 18.17 1.03 μmol/L) and 13(IC_(50) = 8.61 0.45 μmol/L) showed excellent urease inhibitory activity in the series. Molecular modeling studies were performed to understand the binding site with the bimetallic nickel center of the enzyme.Structure-activity relationship has also been established for these compounds. This study identified bisthiobarbiturate as a novel class of urease inhibitors. | Fazal Rahim Muhammad Ali Shifa Ullah Umer Rashid Hayat Ullah Muhammad Taha Muhammad Tariq Javed Wajid Rehman Aftab Ahmad Khan Obaid Ur Rahman Abid Muhammad Bilal | 2016 | Chinese Chemical Letters2016，27，5： | 2 |
| 6 | Plant extract-loaded bacterial cellulose composite membrane for potential biomedical applications显示文摘Bacterial cellulose(BC)has been extensively explored as biomaterial for various biomedical applications owing to its non-toxic nature and unique structural morphology and impressive physicochemical and mechanical properties.However,its high production cost and lack of antimicrobial activity have restricted its large-scale production and therapeutic applications.Therefore,the current study is aimed to devise a strategy for low-cost BC production and develop its composite with bioactive materials to bless it with antimicrobial activity.Herein,5 mm thick reticulated fibrous and highly porous BC was produced by utilizing the wasted rotten tomatoes as the production medium.The produced bacterial cellulose waste(BCW)(i.e.,produced from wastes)was ex-situ modified with bioactive plant extract(PE)obtained from Euclea schimperi,and the bactericidal activity of the developed BCW/PE was evaluated against Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli through disc diffusion and colony forming unit(CFU)count methods.The BCW/PE composite showed high bactericidal activities against S.aureus and produced clear inhibition zone whereas negligible activity was observed against E.coli,indicating its bactericidal activity mainly against the Gram-positive bacterium.Overall,this study illustrates that there is a huge potential for developing valuable biomaterials from food wastes and utilizing their liquid holding capabilities for value-added applications in medical and pharmaceutical fields. | Atiya Fatima Sumayia Yasir MohdShariq Khan Sehrish Manan Muhammad Wajid Ullah Mazhar Ul-Islam | 2021 | Journal of Bioresources and Bioproducts2021，6，1： | 1 |
| 7 | Fabrication of NiO coated SiO_2 and SiO_2 coated NiO for the removal of Pb^(2+) ions显示文摘We have prepared silica,SiO2coated NiO and NiO coated SiO2by sol-gel method.The physicochemical properties of the desired materials were investigated by surface charge properties,scanning electron microscopy(SEM),energy dispersive X-ray(EDX) spectroscopy,surface area measurements and X-ray diffraction(XRD) analyses.The point of zero charge(PZC) of the solid was determined by the salt addition method.In coated materials,two PZC values were noted representing the surface charge of their counterparts.The SEM image of SiO2coated NiO displays a uniform coating of silica on the surface of NiO whereas in case of NiO coated SiO2,a honeycomb like appearance was observed with highly porous structures.In the diffractograms of NiO,the characteristic peaks were suppressed in NiO coated silica however,no diffraction peak could be seen in SiO2coated NiO.Batch adsorption technique was applied for the removal of Pb2+ions from aqueous solution.The sorption trend for Pb2+ions was observed in the order of NiO coated SiO2> SiO2coated NiO > NiO > SiO2.This trend confirms that the coated materials have more sorption capacities than their parent counterparts. | Saba Noor Muhammad Waseem Umer Rashid Muhammad Anis-ur-Rehman Wajid Rehman Khalid Mahmood | 2014 | Chinese Chemical Letters2014，25，5： | 1 |
| 8 | Dietary vitamin E in White Leghorn layer breeder hens: a strategy to combat aflatoxin B1-induced damage显示文摘 | Wajid Arshad Khan Muhammad Zargham Khan Ahrar Khan Zahoor Ul Hassan Shahid Rafique Muhammad Kashif Saleemi Abdul Ahad | 2014 | Avian Pathology2014，，5： | 1 |
| 9 | Syntheses,Spectral Studies and Bioanalyses of Some Triorganotin(IV) Complexes of Cephlaxine显示文摘Five novel triorganotin(IV) complexes have been synthesized by refluxing tri-methyl, triethyl, tributyl, triphenyl and tribenzyltin chloride with Cephlaxine. These compounds were characterized by spectroscopic (IR, 1H, 13C, 119Sn NMR) techniques and elemental analysis. The results obtained through these techniques are in full agreement with the proposed 1:1 stoichiometry. The synthesized compounds were than tested against various microorganisms and fungi. The results of new products obtained showed that the triphenyltin(IV) complex displayed promising activity against all types of bacteria and fungi used while all other compounds showed significant antibacterial and antifungal activity. | Wajid Rehman Bakhtiar Muhammad Farman Ali Sardar Atif | 2008 | Chinese Journal of Structural Chemistry2008，27，7： | 1 |
| 10 | Implantable versatile oxidized bacterial cellulose membrane for postoperative HNSCC treatment via photothermal-boosted immunotherapy显示文摘The recurrence of head and neck squamous cell carcinoma(HNSCC)after surgical resection continues to pose a major challenge to cancer treatment.Advanced HNSCC exhibits a low response rate to immune checkpoint blockade(ICB),while photothermal therapy(PTT)can increase the infiltration of immune cells to make tumors more susceptible to cancer immunotherapy.In this regard,we designed and constructed a novel multifunctional nanocomposite comprised of oxidized bacterial cellulose(OBC),thrombin(TB),and gold nanocages(AuNCs)containing anti-programmed death 1(PD-1)antibody(αPD-1@AuNCs),which allows the combination of therapies with remarkable postoperative antitumor immunity to control local tumor recurrence.TheαPD-1@AuNCs displayed high light-to-heat conversion efficiency and induced pyroptosis under near infrared(NIR)irradiation,which activated a potent antitumor immune response.More importantly,the therapeutic system could induce tumor pyroptosis and enhance antitumor immune response by increasing T-cell infiltration and reducing the immune suppressive cells,when combined with local ICB therapy,which effectively avoided the tumor recurrence in a HNSCC postoperative mice model.Overall,the newly developed multifunctional nanocomposites could be a promising candidate for the treatment of postoperative HNSCC. | Jun-Jie Zhou Xiao-Hong Li Peng-Yu He Fu-Yu Qi Muhammad Wajid Ullah Shu-Jin Li Yuan-Tong Liu Lin-Lin Bu Guang Yang Zhi-Jun Sun | 2023 | Nano Research2023，16，1： | 0 |
| 11 | Evaluation of cotton germplasm for morphological and biochemical host plant UPdates resistance traits against sucking insect pests complex显示文摘Background:Sucking insect pests cause severe damage to cotton crop production.The development of insect resistant cotton cultivars is one of the most effective measures in curtailing the yield losses.Considering the role of morphological and biochemical host plant resista nee(HPR)traits in plant defense,12 cotton genotypes/varieties were evaluated for leaf area,leaf glanding,total soluble sugars,total soluble proteins,total phenolics,tannin and total flavonoids against fluctuating populations of whitefly,thrips and jassid under field conditions.Results:The population of these insects fluctuated during the growing seas on and remained above threshold level(whitefly>5,thrips>(8-10)f or jassid>1 per leaf)during late June and early July.Strong and negative association of whitefly(r=-0.825)and jassid(r=-0.929)with seed cotton yield was observed.Mean population of insects were the highest in Glandless-1 followed by NIA-82 and NIA-M30.NIAB-Kiran followed by NI AB-878 and Sadori were the most resistant,with the mean population of 1.41,1.60,1.66(whitefly);2.24,232,2.53(thrips)and 037,0.31,036(jassid),respectively.The resistant variety NIAB-Kiran showed less soluble sugars(8.54 mg.g^(-1)),soluble proteins(27.11 mg.g^(-1))and more phenolic(36.56 mg.g^(-1))and flavonoids(13.10mg.g^(-1))as compared with the susceptible check Glandless-1.Moreover,all insect populations were positively correlated with total soluble sugars and proteins.Whitefly populations exhibited negative response to leaf gossypol glands,total phenolics,tannins and flavonoids.The thrips and jassid populations had a significant and negative correlation with these four biochemical HPR traits.Conclusion:The ide ntified resistant resources and HPR traits can be deployed against sucking in sect pests'complex in future breeding programs of developing insect resistant cotton varieties. | RIZWAN Muhammad ABRO Saifullah ASIF Muhammad Usman HAMEED Amjad MAH BOOB Wajid DEHO Zaheer Ahmed SIAL Mahboob Ali | 2021 | Journal of Cotton Research2021，4，3： | 0 |
| 12 | Optoelectronic and elastic properties of metal halides double perovskites Cs_(2)InBiX_(6)(X = F, Cl, Br, I)显示文摘Structural geometry, electronic band gaps, density of states, optical and mechanical properties of double perovskite halides Cs2InBiX6(X = F, Cl, Br, I) are investigated using the density functional theory. These compounds possess genuine perovskite stoichiometry, evaluated using various geometry-based indices like tolerance factor, octahedral factor, and formation energy. The fundamental electronic band gaps are direct and valued in the range 0.80–2.79 e V. These compounds have narrow band gaps(except Cs2InBiX6) due to strong orbital coupling of the cations. The valence band maximum and conduction band minimum are confirmed to be essentially of In 5 s and Bi 6 p characters, respectively. The splitting of Bi 6 p bands due to strong spin-orbit coupling causes reduction in the band gaps. These compounds have large dispersion in their bands and very low carrier effective masses. The substitution of halogen atoms has great influence on the optical properties. The mechanical properties reveal that Cs2InBiX6(X = F, Cl, Br, I) satisfy the stability criteria in cubic structures. | Muhammad Saeed Izaz Ul Haq Shafiq Ur Rehman Akbar Ali Wajid Ali Shah Zahid Ali Qasim Khan Imad Khan | 2021 | Chinese Optics Letters2021，19，3： | 0 |
| 13 | COVIDX: Computer-aided diagnosis of COVID-19 and its severity prediction with raw digital chest X-ray scans显示文摘Background: Coronavirus disease (COVID-19) is a contagious infection caused by severe acute respiratory syndrome coronavirus-2 (SARS-COV-2) and it has infected and killed millions of people across the globe.Objective: In the absence or inadequate provision of therapeutic treatments of COVID-19 and the limited convenience of diagnostic techniques, there is a necessity for some alternate spontaneous screening systems that can easily be used by the physicians to rapidly recognize and isolate the infected patients to circumvent onward surge. A chest X-ray (CXR) image can effortlessly be used as a substitute modality to diagnose the COVID-19.Method: In this study, we present an automatic COVID-19 diagnostic and severity prediction system (COVIDX) that uses deep feature maps of CXR images along with classical machine learning algorithms to identify COVID-19 and forecast its severity. The proposed system uses a three-phase classification approach (healthy vs unhealthy, COVID-19 vs pneumonia, and COVID-19 severity) using different conventional supervised classification algorithms.Results: We evaluated COVIDX through 10-fold cross-validation, by using an external validation dataset, and also in a real setting by involving an experienced radiologist. In all the adopted evaluation settings, COVIDX showed strong generalization power and outperforms all the prevailing state-of-the-art methods designed for this purpose.Conclusions: Our proposed method (COVIDX), with vivid performance in COVID-19 diagnosis and its severity prediction, can be used as an aiding tool for clinical physicians and radiologists in the diagnosis and follow-up studies of COVID-19 infected patients.Availability: We made COVIDX easily accessible through a cloud-based webserver and python code available at https://sites.google.com/view/wajidarshad/software and http://gffzz188fe103f8f1460asqcp6ovpx65q069vv.ffgz.tsg.suse.edu.cn/wajidarshad/covidx, respectively. | Wajid Arshad Abbasi Syed Ali Abbas Saiqa Andleeb Maryum Bibi Fiaz Majeed Abdul Jaleel Muhammad Naveed Akhtar | 2022 | Quantitative Biology2022，10，2： | 0 |
| 14 | 社会政治地理和生态压力对传统牧业制度的影响综述(英文)显示文摘Pastoralism is a viable socio-economic system-shaped by landless and agro-pastoral communities in many pastoral regions of the world. This system is mainly based on seasonal migration of pastoralists and their livestock herds between upland and lowland pastures. Traditionally pastoral activities make significant contributions to mountain livelihood subsistence, regional economies and environmental sustainability. However, the pastoralist’s lifestyle and their economies are increasingly confronted to various socio-political, economic and ecological stresses from the last few decades. Extensive literature reviewed on this subject with the aim to explore the current emerging challenges faced by pastoral communities in different pastoral regions. It has been revealed from literature that the prevalent socio-political and economic stress on pastoralism caused by modernization, insecure land tenure, integration of market economy, civil insecurities and pastoralist’s exclusion in states policies while ecological stress on pastoral activities emerged with increasing focus on nature conservation in pastoral regions and climate change induced hazards and disasters. As a consequence of these challenges, pastoral households are abandoning livestock herding–as a traditional way of life and are in continuous transition to transform their pastoral practices and institutions. Thus, the attention and consultation of key stakeholders are needed toward pastoral resource development that improve and sustain traditional pastoral practices in a socio-politically and ecologically stressed environment of the world. | MUHAMMAD Khurshid MOHAMMAD Nafees ABDULLAH Khan MEHMET Somuncu ASHFAQ Ahmad Khan WAJID Rashid | 2019 | Journal of Geographical Sciences2019，29，10： | 0 |
| 15 | Synthesis and applications of fungal mycelium-based advanced functional materials显示文摘Over the last couple of decades,the introduction of living systems to material science for the synthesis of functional materials from biological resources is receiving immense consideration.This is also in accordance with the need for green and sustainable development of new materi-als.For example,the growing concerns of the degradation of synthetic plastics are shifting the direction of materials-related research to the use of polymeric materials acquired from renewable resources.For example,the fungal mycelium-based materials are produced by growing the vegetative part of mushroom-forming fungi on different organic substrates.Such fungi are known for their ability to degrade agricultural wastes such as straws and sawdust.The mycelium-based composites having tailored structural,physical,chemical,mechanical,and biological properties are relying on the strain,feeding substrate,and the manufacturing process.The mycelium cell wall mainly contains the chitin,glucans,proteins,and lipids,whose concentrations depend upon the feeding substrate that ultimately defines the final properties of the synthesized materials.The mycelium-based functional materials with tunable properties are synthesized by selecting the desired components and the synthesis method.The pure and composites of stiff,elastic,porous,less dense,fast-growing,and low-cost mycelium-derived materials with efficient antimicrobial,antioxidant,and skin whitening properties pave their way in various applications such as construction,packaging,medicine,and cosmetics.This review describes the synthesis and structural organization of mycelium-based materials.It further discusses the effect of different factors on the material properties.Finally,it summarizes different applications of mycelium-based materials in medicine,cosmetics,packaging,and construction fields. | Sehrish Manan Muhammad Wajid Ullah Mazhar Ul-Islam Omar Mohammad Atta Guang Yang | 2021 | Journal of Bioresources and Bioproducts2021，6，1： | 0 |
| 16 | Bacterial cellulose/glycolic acid/glycerol composite membrane as a system to deliver glycolic acid for anti-aging treatment显示文摘Glycolic acid(GA),as an anti-aging skincare ingredient,plays a pivotal role in anti-aging treatment.However,its benefits could be overshadowed due to its side effects including skin burning and irritation when overused.Bacterial cellulose(BC)is a highly pure form of cellulose,biosynthesized in the form of a swollen membrane by several kinds of bacteria that was demonstrated to modulate the release of model drugs owing to its porous and 3D fibrous network structure,and glycerol(GL),as a plasticizer,could enhance the controlled drug delivery.Herein,we report a topical controlled drug delivery system based on BC membrane,GA and GL for controlling sustainable release of GA to reduce its side effects on the skin,while maintaining its prolonged and maximum therapeutic effect.The results showed that the incorporation of GL increased the malleability and flexibility of BC/GA/GL membrane,as compared with BC/GA membrane.In addition,the GL enhanced the control of the GA delivery,as evidenced by a higher swelling capacity and thereby a slower release of the GA from BC/GA/GL membrane.More importantly,in vitro study indicated that both BC/GA and BC/GA/GL membranes could effectively stimulate endogenous collagen synthesis in NIH3T3 cells owing to the release of GA,and that BC/GA/GL membrane is more conducive to a long-term cell adhesion,spreading,and proliferation of NIH3T3 and HaCaT cells due to its lower and sustainable release of GA than BC/GA membrane.This study suggests the BC/GL/GA composite membrane holds great promise as an appealing platform to control the release of GA to greatly promote renewal of skin cells for effective anti-aging treatment. | Bricard Mbituyimana Lin Mao Sanming Hu Muhammad Wajid Ullah Kun Chen Lina Fu Weiwei Zhao Zhijun Shi Guang Yang | 2021 | Journal of Bioresources and Bioproducts2021，6，2： | 0 |
| 17 | Reinforcing Artificial Neural Networks through Traditional Machine Learning Algorithms for Robust Classification of Cancer显示文摘Machine Learning(ML)-based prediction and classification systems employ data and learning algorithms to forecast target values.However,improving predictive accuracy is a crucial step for informed decision-making.In the healthcare domain,data are available in the form of genetic profiles and clinical characteristics to build prediction models for complex tasks like cancer detection or diagnosis.Among ML algorithms,Artificial Neural Networks(ANNs)are considered the most suitable framework for many classification tasks.The network weights and the activation functions are the two crucial elements in the learning process of an ANN.These weights affect the prediction ability and the convergence efficiency of the network.In traditional settings,ANNs assign random weights to the inputs.This research aims to develop a learning system for reliable cancer prediction by initializing more realistic weights computed using a supervised setting instead of random weights.The proposed learning system uses hybrid and traditional machine learning techniques such as Support Vector Machine(SVM),Linear Discriminant Analysis(LDA),Random Forest(RF),k-Nearest Neighbour(kNN),and ANN to achieve better accuracy in colon and breast cancer classification.This system computes the confusion matrix-based metrics for traditional and proposed frameworks.The proposed framework attains the highest accuracy of 89.24 percent using the colon cancer dataset and 72.20 percent using the breast cancer dataset,which outperforms the other models.The results show that the proposed learning system has higher predictive accuracies than conventional classifiers for each dataset,overcoming previous research limitations.Moreover,the proposed framework is of use to predict and classify cancer patients accurately.Consequently,this will facilitate the effective management of cancer patients. | Muhammad Hammad Waseem Malik Sajjad Ahmed Nadeem Ishtiaq Rasool Khan Seong-O-Shim Wajid Aziz Usman Habib | 2023 | Computers, Materials & Continua2023，，5： | 0 |
| 18 | A decline in snow cover area of Passu and Ghulkin valleys between 1995 and 2022显示文摘The global cryosphere is experiencing accelerated melting due to climate change.Currently,the Karakoram anomaly is under discussion with a debate about the possibility that the anomaly may have recently ended.This study aims to evaluate the up-to-date changes in snow cover in the western Karakoram region.We observed the snow cover changes in Passu and Ghulkin valleys in the Hunza River basin(HRB)of the Karakoram through multitemporal Landsat satellite data between 1995 and 2022.We found a significant reduction in snow cover in these valleys,with an average reduction rate of 0.42 km~2/yr,resulting in a total reduction of~11.46 km~2 between 1995 and 2022.This reduction in snow cover is consistent with the mass loss of glaciers in the Karakoram region in recent years.The decline in snow cover in these valleys is also consistent with the meteorological data.The temperature in summer(June)has significantly increased whereas the precipitation in the accumulation season(March)has decreased.These rapid changes suggest that it is crucially important to monitor the snow cover on a regular basis to support downstream management of snowmelt runoff.In addition,there is a need of planning for mitigation and adaptation strategies for snow-related hazards. | Imran HUSSAIN Mumtaz ALI Sher MUHAMMAD Wajid HASSAN Salar ALI Zakir HUSSAIN Syed Hammad ALI Shaukat ALI Muhammad Younis KHAN | 2023 | Journal of Mountain Science2023，20，12： | 0 |
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