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| 1 | 光和湿度对土红、朱砂和铅丹变色的影响显示文摘壁画颜料变色是敦煌壁画最严重的病害之一。敦煌壁画中,红色颜料主要是土红、朱砂和铅丹,变色最严重的是铅丹。影响壁画颜料变色的因素,过去我们作过一些研究。1978年到1983年,我们和化工部兰州涂料研究所合作,对莫高窟壁画颜料进行了分析研究。44个洞窟的棕黑色颜料, | 李最雄 Stefan Michalski | 1989 | 敦煌研究1989，，3： | 18 |
| 2 | Gastric ghrelin in relation to gender,stomach topography and Helicobacter pylori in dyspeptic patients显示文摘AIM:To investigate the level of gastric ghrelin in stomach mucosa of dyspeptic patients in relation to Helicobacter pylori(H pylori)infection,bacterial cytotoxicity,topography and gender. METHODS:The study comprised 40 premenopausal women(19 H pylori positive)and 48 men(17 H pylori positive)with functional dyspepsia.All gastric biopsy specimens revealed normal mucosa or non-atrophic gastritis.Gastric ghrelin concentration was determined by Enzyme linked immunosorbent assay.The cagA and vacA strains of bacterial DNA were identified by multiplex polymerase chain reaction. RESULTS:In general,infection with H pylori causedan increase in gastric ghrelin level regardless of gender and stomach topography.Significantly more hormone was present in both,noninfected and H pylori positive female samples,as compared to males.The distribution of bacterial strains showed cagA(+)vacA s1m1 and cagA(-)vacA s2m2 genotypes as the most common infections in the studied population.A tendency to higher ghrelin levels was observed in less cytotoxic (cagA negative)strain-containing specimens from the antrum and corpus of both gender groups(without statistical significance). CONCLUSION:An increase in gastric ghrelin levels at the stage of non-atrophic gastritis in H pylori positive patients,especially in those infected with cagA(-) strains,can exert a gastroprotective effect. | Krystyna Stec-Michalska Sebastian Malicki Blazej Michalski Lukasz Peczek Maria Wisniewska-Jarosinska Barbara Nawrot | 2009 | World Journal of Gastroenterology2009，15，43： | 10 |
| 3 | 胰腺的癌症病人的反应评估追随者 neoadjuvant 治疗显示文摘 Pancreatic ductal adenocarcinoma(PDAC) is one of the most aggressive human neoplastic entities,with a very poor prognosis characterized by a high mortality rate and short survival.This is due both to its aggressive biological behaviour and the high incidence of locally advanced stages at the time of the initial diagnosis.The limits of resectability and the role of neoadjuvant(radio) chemotherapy for PDAC management are still unclear.A recently published article by Kats et al compared the radiological,surgical and histopathological results of 129 patients with borderline resectable tumors undergoing neoadjuvant treatment followed by surgery.Although post-neoadjuvant treatment imaging implied a low response rate,a high rate of complete resections was achieved.This seems to confirm that,though radiology has made a significant progress in defining locally advanced PDAC,there is place for further improvement.In particular,the differentiation between radiotherapy-induced scarring/fibrosis and cancer-associated desmoplasia remains a clinical/radiological challenge.Though selection of patients with occult systemic disease is possible with neoadjuvant treatment,downstaging does not seem to occur frequently.Thus,development of novel,more aggressive(radio) chemotherapy regimens is required to improve prognosis of patients with locally unresectable but not systemically micro-metastasized tumors. | Chiara Tosolini Christoph W Michalski Jrg Kleeff | 2013 | World Journal of Gastrointestinal Surgery2013，5，2： | 7 |
| 4 | Update on surgical treatment of pancreatic neuroendocrine neoplasms显示文摘Pancreatic neuroendocrine neoplasms(PNENs) are rare and account for only 2%-4% of all pancreatic neoplasms. All PNENs are potential(neurendocrine tumors PNETs) or overt(neuroendocrine carcinomas PNECs) malignant,but a subset of PNETs is low-risk. Even in case of low-risk PNETs surgical resection is frequently required to treat hormone-related symptoms and to obtain an appropriate pathological diagnosis. Low-risk PNETs in the body and the tail are ideal for minimallyinvasive approaches which should be tailored to the individual patient. Generally,surgeons must aim for parenchyma sparing in these cases. In high-risk and malignant PNENs,indications for tumor resection are much wider than for pancreatic adenocarcinoma,in many cases due to the relatively benign tumor biology. Thus,patients with locally advanced and metastatic PNETs may benefit from extensive resection. In experienced hands,even multi-organ resections are accomplished with acceptable perioperative morbidity and mortality rates and are associated with excellent long term survival. However,poorly differentiated neoplasms with high proliferation rates are associated with a dismal prognosis and may frequently only be treated with chemotherapy. The evidence on surgical treatment of PNENs stems from reviews of mostly singlecenter series and some analyses of nation-wide tumor registries. No randomized trial has been performed to compare surgical and non-surgical therapies in potentially resectable PNEN. Though such a trial would principally be desirable,ethical considerations and the heterogeneity of PNENs preclude realization of such a study. In the current review,we summarize recent advances in the surgical treatment of PNENs. | Jan G D’Haese Chiara Tosolini Güralp O Ceyhan Bo Kong Irene Esposito Christoph W Michalski J?rg Kleeff | 2014 | World Journal of Gastroenterology2014，20，38： | 4 |
| 5 | 新疆吐-哈地区硝酸盐巨量富集特征及机制探讨显示文摘吐-哈地区是我国目前发现的唯一的硝酸盐巨量堆积分布区,蕴藏有超大型钠硝石矿床,分布着大小不一的硝酸盐型盐湖或干盐湖(郑喜玉等,1995),已发现库姆塔格、大南湖、西戈壁、裤子山、大洼地、乌宗布拉克等许多硝酸盐矿床(蔡克勤等,1992;高月珍,1993;葛文胜等,2007;李博昀等,2005;刘国庆等,2005),在区域上已构成一个规模巨大的硝酸盐成矿区带。 | 葛文胜 Michalski G. 魏乐军 王凡 蔡克勤 桑少杰 邱斌 付强 | 2010 | 矿床地质2010，29，S1： | 3 |
| 6 | Radioprotective thermally generated free-radical dextrins显示文摘Effect of doses of the X-ray radiation from 0 to 400 Gy upon granular cornstarch and dextrins (British gums, BG) thermally generated from it at 230-300℃ was recognized with quantitative EPR and IR ab-sorption spectroscopy, molecular mass distribution in the depolymerization products, Scanning Elec-tron Microscopy, and X-ray diffractometry. Fractal analysis of the profiles of molecular mass distribu-tion showed that the depolymerization involved debranching of amylopectin. Roasting of cornstarch produced BG which differed in concentration and EPR parameters of stable free radicals from BG generated by X-ray radiation. Two types of stable free radicals, with Gaussian and Lorentzian shapes of EPR signals, were recognized. The shapes of the signals and temperature dependence on free radical intensity indicated exchanging interactions of the antiferromagnetic type, causing partial quenching of the spins at-196℃ (77K). Upon X-ray irradiation, new radicals were generated, the number and stability of which strongly depended on the types of radicals present before irradiation. These radicals slowly ceased because of a repolymerization of BG on storage. | Piotr TOMASIK Oskar MICHALSKI Ewa BIDZINSKA Antonina CEBULSKA-WASILEWSKA Krystyna DYREK Maciej FIEDOROWICZ Pawe OLKO | 2008 | Chinese Science Bulletin2008，53，7： | 3 |
| 7 | Geomorphologic Characteristics of Polygonal Features on Chloride-Bearing Deposits on Mars: Implications for Martian Hydrology and Astrobiology显示文摘Over 600 chloride-bearing deposits(chlorides) have been identified on the southern highlands of Mars. These chlorides have critical implications for hydrology and astrobiology: they are indicators of an evaporating super saturated solution, and they could have provided habitat environments for halophilic microorganisms and preserved organic matter. One of the prominent geomorphology characteristics of these chloridebearing regions is the polygonal features within them. The origin of these polygonal features is still in debate. In this study, we have surveyed 153 locations of chlorides using 441 high resolution imaging science experiment(Hi RISE) images to characterize the geomorphology of polygonal features. We identified 3 types of polygonal features of distinct geomorphologic characteristics: fractures, raised ridges, and transitional polygons between fractures and raised ridges. We evaluate previously proposed hypotheses of the formation of the polygonal features, and suggest that the 3 types of polygonal features are indicators of different stages of salt crust formation. Salt crust is usually formed through multiple groundwater activities, and it often occurs in playa environment on Earth. The unique hydrological and astrobiological implications of the chlorides with polygonal features make these deposits of high priority for future landed on and/or sample return exploration missions of Mars. | Binlong Ye Jun Huang Joseph Michalski Long Xiao | 2019 | Journal of Earth Science2019，30，5： | 2 |
| 8 | Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer显示文摘 | Stefan Eser Nina Reiff Marlena Messer Barbara Seidler Kathleen Gottschalk Melanie Dobler Maren Hieber Andreas Arbeiter Sabine Klein Bo Kong Christoph W. Michalski Anna Melissa Schlitter Irene Esposito Alexander J. Kind Lena Rad Angelika E. Schnieke Manuel | 2013 | Cancer Cell2013，，： | 2 |
| 9 | High-resolution,three-dimensional magnetic resonance imaging axial load dynamic study improves diagnostics of the lumbar spine in clinical practice显示文摘BACKGROUND The response to axial physiological pressure due to load transfer to the lumbar spine structures is among the various back pain mechanisms.Understanding the spine adaptation to cumulative compressive forces can influence the choice of personalized treatment strategies.AIM To analyze the impact of axial load on the spinal canal’s size,intervertebral foramina,ligamenta flava and lumbosacral alignment.METHODS We assessed 90 patients using three-dimensional isotropic magnetic resonance imaging acquisition in a supine position with or without applying an axial compression load.Anatomical structures were measured in the lumbosacral region from L1 to S1 in lying and axially-loaded magnetic resonance images.A paired t test atα=0.05 was used to calculate the observed differences.RESULTS After axial loading,the dural sac area decreased significantly,by 5.2%on average(4.1%,6.2%,P<0.001).The intervertebral foramina decreased by 3.4%(2.7%,4.1%,P<0.001),except for L5-S1.Ligamenta flava increased by 3.8%(2.5%,5.2%,P<0.001),and the lumbosacral angle increased.CONCLUSION Axial load exacerbates the narrowing of the spinal canal and intervertebral foramina from L1-L2 to L4-L5.Cumulative compressive forces thicken ligamenta flava and exaggerate lumbar lordosis. | Tomasz Lorenc Marek Gołębiowski Wojciech Michalski Wojciech Glinkowski | 2022 | World Journal of Orthopedics2022，13，1： | 2 |
| 10 | Cancer-Stellate Cell Interactions Perpetuate the Hypoxia-Fibrosis Cycle in Pancreatic Ductal Adenocarcinoma显示文摘 | Mert Erkan Carolin Reiser-Erkan Christoph W. Michalski Stefanie Deucker Danguole Sauliunaite Sylvia Streit Irene Esposito Helmut Friess J?rg Kleeff | 2009 | Neoplasia2009，，： | 2 |
| 11 | Lack of T-cell responses following autologous tumour lysate pulsed dendritic cell vaccination, in patients with relapsed osteosarcoma显示文摘 | Nourredine Himoudi Rebecca Wallace Kathryn Parsley Kimberly Gilmour Alpha-Umaru Barrie Karen Howe Rong Dong Neil Sebire Antony Michalski Adrian Thrasher John Anderson | 2012 | Clinical and Translational Oncology2012，，： | 2 |
| 12 | Is the 1-cm Rule of Distal Bowel Resection Margin in Rectal Cancer Based on Clinical Evidence? A Systematic Review显示文摘 | Krzysztof Bujko MD PhD Andrzej Rutkowski MD PhD George J. Chang MD MS Wojciech Michalski MSc Ewa Chmielik MD PhD Jerzy Kusnierz MD PhD | 2012 | Annals of Surgical Oncology2012，，3： | 2 |
| 13 | The Characteristics and Genesis of the Massive Nitrate Deposits in the Turpan-Hami Basin of Xinjiang,China显示文摘Massive nitrate deposits have been discovered in the Turpan-Hami basin in northwestern China.Previously,large ore grade nitrate minerals were thought only to exist in the Atacama Desert in northern Chile.Estimates of | GE Wensheng Greg MICHALSKI CAI Keqin WANG Fan LIU Yaran | 2014 | Acta Geologica Sinica(English Edition)2014，88，S1： | 2 |
| 14 | All-weather model for sky luminance distribution-preliminary configuration and validation 显示文摘 | Perez R Seals R Michalsky J | 1993 | Solar Energy1993，50，3： | 1 |
| 15 | Childhood and adolescent thyroid carcinoma 显示文摘 | Grigsby PW Gal-or A Michalski JM | 2002 | Cancer2002，95，4： | 1 |
| 16 | Ex vivo cherno- sensitivity testing and gene expression profiling predict response towards adjuvant gerncitabine treatment in pancreatic cancer 显示文摘 | Michalski CW Erkan M Sauliunaite D | 2008 | BrJ Cancer2008，99，5： | 1 |
| 17 | Novel antibacterial peptide derived from bovine aS1-casein显示文摘 | McCann KB Shiell BJ Michalski WP | 2003 | Australian J Dairy Technol2003，58，2： | 1 |
| 18 | Second-generation recombination-based in vivo expression technology for large-scale screening for Vibrio cholerae genes induced during infection of the mouse small intestine显示文摘 | OSORIO C G CRAWFORD J A MICHALSKI J | 2005 | Infect Immun2005，73，2： | 1 |
| 19 | Inorganic oxyhalide by-products in drinking water and ion chromatographic determination methods 显示文摘 | Michalski R | 2005 | Po| J Environ Stud2005，14，： | 1 |
| 20 | Systematic review and meta-analysis of standard and extended lymphadenectomy in pancreaticoduodenectomy for pancreatic cancer显示文摘 | Michalski CW Kleeff J Wente MN | | 0，，03： | 1 |
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