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| 1 | 基本参数法X-射线荧光光谱同时分析镍、钴和铁基合金显示文摘用基本参数法分析了镍、钴和铁基合金,对每种元素在整个含量范围内用单一校准进行了测定,并获得了满意的结果。研究显示,本方法可以采用多通道光谱仪对主次元素进行分析测定。例如,对镍元素来说,在质量分数0%到100%的浓度范围内,准确度达到质量分数0.14%。我们还发现,在铬的分析中,三级激发很显著,对整体强度的贡献率达到2.4%。通过将三级激发考虑进理论强度计算,方法的准确度可由质量分数0.14%提高到0.10%。对灵敏度进行了最小二乘拟合法校准,研究显示二次拟合多项式用单一校准曲线在整个浓度范围内都能给出很好的结果。在多通道光谱仪中,当通道不再适合谱线重叠时,理论强度重叠校正法是有效的手段。 | KATAOKA Yoshiyukki FURUSAWA Eiichi KOHNO Hisayuki ARAI Tomoya MARTIN Al INOUE Hisashi MANTLER Michael | 2009 | 冶金分析2009，29，5： | 9 |
| 2 | Prevalence and determinants of delayed gastric emptying in hospitalised Type 2 diabetic patients显示文摘AIM: To determine the prevalence of delayed gastric emptying (GE) in older patients with Type 2 diabetes mellitus. METHODS: One hundred and forty seven patients with Type 2 diabetes, of whom 140 had been hospitalised, mean age 62.3 ± 8.0 years, HbA1c 9.1% ± 1.9%, treated with either oral hypoglycemic drugs or insulin were studied. GE of a solid meal (scintigraphy), autonomic nerve function, upper gastrointestinal symptoms, acute and chronic glycemic control were evaluated. Gastric emptying results were compared to a control range of hospitalised patients who did not have diabetes. RESULTS: Gastric emptying was delayed (T50 > 85 min) in 17.7% patients. Mean gastric emptying was slower in females (T50 72.1 ± 72.1 min vs 56.9 ± 68.1 min, P = 0.02) and in those reporting nausea (112.3 ± 67.3 vs 62.7 ± 70.0 min, P < 0.01) and early satiety (114.0 ± 135.2 vs 61.1 ± 62.6 min, P = 0.02). There was no correlation between GE with age, body weight, duration of diabetes, neuropathy, current glycemia or the total score for upper gastrointestinal symptoms. CONCLUSION: Prolonged GE occurs in about 20% of hospitalised elderly patients with Type 2 diabetes when compared to hospitalised patients who do not have diabetes. Female gender, nausea and early satiety areassociated with higher probability of delayed GE. | Vladimir Kojecky Jaromir Bernatek Michael Horowitz Stanislav Zemek Jiri Bakala Ales Hep | 2008 | World Journal of Gastroenterology2008，14，10： | 8 |
| 3 | Beneficial effects of nutritional supplements on intestinal epithelial barrier functions in experimental colitis models in vivo显示文摘Acute and chronic colitis affect a huge proportion of the population world-wide.The etiology of colitis cases can be manifold,and diet can significantly affect onset and outcome of colitis.While many forms of acute colitis are easily treatable,chronic forms of colitis such as ulcerative colitis and Crohn’s disease(summarized as inflammatory bowel diseases)are multifactorial with poorly understood pathogenesis.Inflammatory bowel diseases are characterized by exacerbated immune responses causing epithelial dysfunction and bacterial translocation.There is no cure and therapies aim at reducing inflammation and restoring intestinal barrier function.Unfortunately,most drugs can have severe side effects.Changes in diet and inclusion of nutritional supplements have been extensively studied in cell culture and animal models,and some supplements have shown promising results in clinical studies.Most of these nutritional supplements including vitamins,fatty acids and phytochemicals reduce oxidative stress and inflammation and have shown beneficial effects during experimental colitis in rodents induced by dextran sulphate sodium or 2,4,6-trinitrobenzene sulfonic acid,which remain the gold standard in pre-clinical colitis research.Here,we summarize the mechanisms through which such nutritional supplements contribute to epithelial barrier stabilization. | Hilda Vargas-Robles Karla Fabiola Castro-Ochoa Alí Francisco Citalán-Madrid Michael Schnoor | 2019 | World Journal of Gastroenterology2019，25，30： | 5 |
| 4 | Transradial approach for acute stroke intervention: technical procedure and clinical outcomes显示文摘background and purpose Radial artery catheterisation is an alternate route of access that has recently started to gain more widespread use for neuroendovascular procedures,including acute stroke intervention.In this small case series,we present our institution’s outcomes in patients undergoing acute stroke interventions via transradial access.Materials and methods We present a retrospective study of 15 patients who underwent acute stroke intervention via radial artery access.We analyse these patients’periprocedural and clinical outcomes after undergoing mechanical thrombectomy.results A total of 15 consecutive patients were included in the study(9 males and 6 females),and all patients were able to successfully undergo mechanical thrombectomy via radial artery access.The mean time of arterial puncture to reperfusion was 50±28 min(range:15-104).A TICI 2b/3 revascularisation was achieved in 13/15 patients(87%);a TICI 1 and TICI 2a outcome was achieved on the other two patients.One patient incurred an iatrogenic vessel dissection during the procedure.Eight of out 15 patients(53%)had favourable mRS(0-3)at the time of discharge from the hospital.Conclusion Radial artery catheterisation is technically feasible for performing acute stroke interventions with favourable time to revascularisation and good overall clinical outcomes. | Omaditya Khanna Nikolaos Mouchtouris Ahmad Sweid Nohra Chalouhi Ritam Ghosh Fadi Al Saiegh Michael R Gooch Stavropoula Tjoumakaris Robert H Rosenwasser Victor Romo Pascal Jabbour | 2020 | Stroke & Vascular Neurology2020，5，1： | 4 |
| 5 | Diagnostic value and utility of the simplified International Autoimmune Hepatitis Group (IAIHG) criteria in acute and chronic liver disease显示文摘 | Andrew D. Yeoman Rachel H. Westbrook Thawab Al‐Chalabi Ivana Carey Nigel D. Heaton Bernard C. Portmann Michael A. Heneghan | 2009 | Hepatology2009，，： | 3 |
| 6 | Psychosocial mechanisms for the transmission of somatic symptoms from parents to children显示文摘AIM: To examine familial aggregation of irritable bowel syndrome(IBS) via parental reinforcement/modeling of symptoms, coping, psychological distress, and exposure to stress.METHODS:Mothers of children between the ages of8 and 15 years with and without IBS were identified through the Group Health Cooperative of Puget Sound.Mothers completed questionnaires,including the Child Behavior Checklist(child psychological distress),the Family Inventory of Life Events(family exposure to stress),SCL-90R(mother psychological distress),and the Pain Response Inventory(beliefs about pain).Children were interviewed separately from their parents and completed the Pain Beliefs Questionnaire(beliefs about pain),Pain Response Inventory(coping)and Child Symptom Checklist[gastrointestinal(GI)symptoms].In addition,health care utilization data was obtained from the automated database of Group Health Cooperative.Mothers with IBS(n=207)and their 296 children were compared to 240 control mothers and their 335 children,while controlling for age and education.RESULTS:Hypothesis 1:reinforcement of expression of GI problems is only related to GI symptoms,but not others(cold symptoms)in children.There was no significant correlation between parental reinforcement of symptoms and child expression of GI or other symptoms.Hypothesis 2:modeling of GI symptomsis related to GI but not non-GI symptom reporting in children.Children of parents with IBS reported more non-GI(8.97 vs 6.70,P<0.01)as well as more GI(3.24 vs 2.27,P<0.01)symptoms.Total health care visits made by the mother correlated with visits made by the child(rho=0.35,P<0.001 for cases,rho=0.26,P<0.001 for controls).Hypothesis 3:children learn to share the methods of coping with illness that their mothers exhibit.Methods used by children to cope with stomachaches differed from methods used by their mothers.Only 2/16 scales showed weak but significant correlations(stoicism rho=0.13,P<0.05;acceptance rho=0.13,P<0.05).Hypothesis 4:mothers and children share psychological traits such as anxiety,depression,and somatization.Child psychological distress correlated with mother’s psychological distress(rho=0.41,P<0.001 for cases,rho=0.38,P<0.001 for controls).Hypothesis 5:stress that affects the whole family might explain the similarities between mothers and their children.Family exposure to stress was not a significant predictor of children’s symptom reports.Hypothesis 6:the intergenerational transmission of GI illness behavior may be due to multiple mechanisms.Regression analysis identified multiple independent predictors of the child’s GI complaints,which were similar to the predictors of the child’s non-GI symptoms(mother’s IBS status,child psychological symptoms,child catastrophizing,and child age).CONCLUSION:Multiple factors influence the reporting of children’s gastrointestinal and non-gastrointestinal symptoms.The clustering of illness within families is best understood using a model that incorporates all these factors. | Miranda AL van Tilburg Rona L Levy Lynn S Walker Michael Von Korff Lauren D Feld Michelle Garner Andrew D Feld William E Whitehead | 2015 | World Journal of Gastroenterology2015，21，18： | 2 |
| 7 | Appropriateness of systemic treatments in unresectable metastatic well-differentiated pancreatic neuroendocrine tumors显示文摘AIM:To evaluate systemic treatment choices in unresectable metastatic well-differentiated pancreatic neuroendocrine tumors(PNETs)and provide consensus treatment recommendations.METHODS:Systemic treatment options for pancreatic neuroendocrine tumors have expanded in recent years to include somatostatin analogs,angiogenesis inhibitors,inhibitors of mammalian target of rapamycinand cytotoxic agents.At this time,there is little data to guide treatment selection and sequence.We therefore assembled a panel of expert physicians to evaluate systemic treatment choices and provide consensus treatment recommendations.Treatment appropriateness ratings were collected using the RAND/UCLA modified Delphi process.After studying the literature,a multidisciplinary panel of 10 physicians assessed the appropriateness of various medical treatment scenarios on a 1-9 scale.Ratings were done both before and after an extended discussion of the evidence.Quantitative measurements of agreement were made and consensus statements developed from the second round ratings.RESULTS:Specialties represented were medical and surgical oncology,interventional radiology,and gastroenterology.Panelists had practiced for a mean of15.5 years(range:6-33).Among 202 rated scenarios,disagreement decreased from 13.2%(26 scenarios)before the face-to-face discussion of evidence to 1%(2)after.In the final ratings,46.5%(94 scenarios)were rated inappropriate,21.8%(44)were uncertain,and30.7%(62)were appropriate.Consensus statements from the scenarios included:(1)it is appropriate to use somatostatin analogs as first line therapy in patients with hormonally functional tumors and may be appropriate in patients who are asymptomatic;(2)it is appropriate to use everolimus,sunitinib,or cytotoxic chemotherapy therapy as first line therapy in patients with symptomatic or progressive tumors;and(3)beyond first line,these same agents can be used.In patients with uncontrolled secretory symptoms,octreotide LAR doses can be titrated up to 60 mg every4 wk or up to 40 mg every 3 or 4 wk.CONCLUSION:Using the Delphi process allowed physician experts to systematically obtain a consensus on the appropriateness of a variety of medical therapies in patients with PNETs. | Jonathan R Strosberg George A Fisher Al B Benson Lowell B Anthony Bulent Arslan John F Gibbs Edward Greeno Renuka V Iyer Michelle K Kim William J Maples Philip A Philip Edward M Wolin Dasha Cherepanov Michael S Broder | 2015 | World Journal of Gastroenterology2015，21，8： | 2 |
| 8 | Consensus Statements for Management of Barrett’s Dysplasia and Early-Stage Esophageal Adenocarcinoma, Based on a Delphi Process显示文摘 | Cathy Bennett Nimish Vakil Jacques Bergman Rebecca Harrison Robert Odze Michael Vieth Scott Sanders Laura Gay Oliver Pech Gaius Longcroft–Wheaton Yvonne Romero John Inadomi Jan Tack Douglas A. Corley Hendrik Manner Susi Green David Al Dulaimi Haythem Ali | 2012 | Gastroenterology2012，，2： | 2 |
| 9 | Increased Quality of Life Among Hepatocellular Carcinoma Patients Treated with Radioembolization, Compared with Chemoembolization显示文摘 | Riad Salem Margaret Gilbertsen Zeeshan Butt Khairuddin Memon Michael Vouche Ryan Hickey Talia Baker Michael M. Abecassis Rohi Atassi Ahsun Riaz David Cella James L. Burns Daniel Ganger Al B. Benson Mary F. Mulcahy Laura Kulik Robert Lewandowski | 2013 | Clinical Gastroenterology and Hepatology2013，，： | 2 |
| 10 | Comparison of Intravitreal Bevacizumab versus Triamcinolone for the Treatment of Diffuse Diabetic Macular Edema显示文摘 | Kreutzer Thomas C Al Saeidi Rashid Kook Daniel Wolf Armin Ulbig Michael W Neubauer Aljoscha S Haritoglou Christos | 2010 | Ophthalmologica2010，，4： | 2 |
| 11 | Unintended biological invasions: Does risk vary by trading partner? 显示文摘 | Costello Christopher Springbom Michael McAusland Carol et al | 2007 | Journal of Environmental Economics and Management2007，54，3： | 1 |
| 12 | The many faces of PPAR 显示文摘 | Michael L Mitchell AL | 2005 | Cell2005，123，6： | 1 |
| 13 | The non operative functional management of patients with a rupture of the tendo Achillis leads to low rates of re- rupture显示文摘 | Wallace RG Heyes GJ Michael AL | 2011 | The Journal of Bone and Joint Surgery British Volume2011，93，10： | 1 |
| 14 | Systemic inflammatory parameters in patients with atherosclerosis of the coronary and peripheral arteries 显示文摘 | Michael E Holger R Ralf J et al | 1999 | Arterioscler Thromb Vasc Biol1999，19，： | 1 |
| 15 | Knowledge Management and Data Mining for Marketing 显示文摘 | MICHAEL J etc al | 2001 | Decision Support Systems2001，31，1： | 1 |
| 16 | Evaluation of ultrahigh temperature ceramics for aero- propulsion use显示文摘 | STANLEY R L ELIZABETH J O MICHAEL C H et al | 2002 | Journal of the European Ceramic Society2002，22，： | 1 |
| 17 | Erratum to: The inci- dence of deep vein thrombosis and pulmonary embolism following cast immobilisation and early functional bracing of Tendo Achilles rupture without thromboprophylaxis 显示文摘 | Heyes GJ Tucker A Michael AL | 2015 | Eur J Trauma Emerg Surg2015，41，3： | 1 |
| 18 | The definition and classification of dry eye disease:report of the Definition and Classification Subcommittee of the International Dry Eye Workshop(2007)显示文摘 | Michael AL Baudouin C Gary NF | 2007 | Ocul Surf2007，5，2： | 1 |
| 19 | The role of CCR5 and CCR2 polymorphisms in HIV-1 transmission and disease progression显示文摘 | Michael NL Louie LG Rohrbaugh AL | 1997 | Nat Med1997，3，10： | 1 |
| 20 | Anaerobic digestion o fprocessed municipal solid waste using a novel highsolids reactor maximum solids levels and mixing re-quirements 显示文摘 | CHRISTOPHER J RIVARD MICHAEL E H IMME’LTODD B V INZANT e? al | 1990 | Biotechnology Letters1990，12，3： | 1 |
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