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| 1 | Chikungunya virus,epidemiology,clinics and phylogenesis:A review显示文摘Chikungunva virus is a mosquito-transmitted alphavirus that causes chikungunva fever,a febrile illness associated with severe arthralgia and rash.Chikungunva virus is transmitted by culicine mosquitoes:Chikungunya virus replicates in the skin,disseminates to liver,muscle,joints.lymphoid tissue and brain,presumably through the blood.Phylogenetic studies showed that the Indian Ocean and the Indian subcontinent epidemics were caused by two different introductions of distinct strains of East/Central/South African genotype of CHIKV.The paraphyletic grouping of African CHIK viruses supports the historical evidence that the virus was introduced into Asia from Africa.Phylogenetic analysis divided Chikungunva virus isolates into three distinct genotypes based on geographical origins:the first,the West Africa genotype,consisted of isolates from Senegal and Nigeria;the second contained strains from East/Central/South African genotype,while the third contained solely Asian.The most recent common ancestor for the recent epidemic,which ravaged Indian Ocean islands and Indian subcontinent in 2004- 2007.was found to date in 2002.Asian lineage dated about 1952 and exhibits similar spread patterns of the recent Indian Ocean outbreak lineage,with successive epidemics detected along an eastward path.Asian group splitted into two clades:an Indian lineage and a south east lineage.Outbreaks of Chikungunya virus fever in Asia have not been associated necessarily with outbreaks in Africa.Phylogenetic tools can reconstruct geographic spread of Chikungunva virus during the epidemics wave.The good management of patients with acute Chikungunva virus infection is essential for public health in susceptible areas with current Aedes spp activity. | Alessandra Lo Presti Alessia Lai Eleonora Cella Gianguglielmo Zehender Massimo Ciccozzi | 2014 | Asian Pacific Journal of Tropical Medicine2014，7，12： | 8 |
| 2 | Molecular epidemiology and phylogeny of Nipah virus infection:A mini review显示文摘Nipah virus(Ni V) is a member of the genus Henipavirus of the family Paramyxoviridae,characterized by high pathogenicity and endemic in South Asia.It is classified as a Biosafety Level-4(BSL-4) agent.The case-fatality varies from 40%-70% depending on the severity of the disease and on the availability of adequate healthcare facilities.At present no antiviral drugs are available for Ni V disease and the treatment is just supportive.Phylogenetic and evolutionary analyses can be used to help in understanding the epidemiology and the temporal origin of this virus.This review provides an overview of evolutionary studies performed on Nipah viruses circulating in different countries.Thirty phylogenetic studies have been published from 2000 to 2015 years,searching on pub-med using the key words ‘Nipah virus AND phylogeny' and twenty-eight molecular epidemiological studies from 2006 to 2015 have been performed,typing the key words ‘Nipah virus AND molecular epidemiology'.Overall data from the published study demonstrated as phylogenetic and evolutionary analysis represent promising tools to evidence NiV epidemics,to study their origin and evolution and finally to act with effective preventive measure. | Silvia Angeletti Alessandra Lo Presti Eleonora Cella Massimo Ciccozzi | 2016 | Asian Pacific Journal of Tropical Medicine2016，9，7： | 4 |
| 3 | Epidemiological network analysis in HIV-1 B infected patients diagnosed in Italy between 2000 and 2008显示文摘 | Annapaola Callegaro Valentina Svicher Claudia Alteri Alessandra Lo Presti Daniela Valenti Antonio Goglio Marco Salemi Eleonora Cella Carlo Federico Perno Massimo Ciccozzi Franco Maggiolo | 2011 | Infection, Genetics and Evolution2011，，3： | 2 |
| 4 | Zika virus spreading in South America: evolutionary analysis of emerging neutralizing resistant Phe279Ser strains显示文摘Objective: To investigate the genetic diversity of Zika virus(ZIKV) and the relationships existing among these circulating viruses worldwide. To evaluate the genetic polymorphisms harboured from ZIKV that can have an influence on the virus circulation. Methods: Three different ZIKV dataset were built. The first dataset included 63 E gene sequences, the second one 22 NS3 sequences and the third dataset was composed of 108 NS5 gene sequences. Phylogenetic and selective pressure analysis was performed. The edited nucleic acid alignment from the Envelope dataset was used to generate a conceptual translation to the corresponding peptide sequences through UGene software. Results: The phylogeographic reconstruction was able to discriminate unambiguously that the Brazilian strains are belonged to the Asian lineage. The structural analysis reveals instead the presence of the Ser residue in the Brazilian sequences(however already observed in other previously reported ZIKV infections) that could suggest the presence of a neutralization-resistant population of viruses. Conclusions: Phylogenetic, evolutionary and selective pressure analysis contributed to improve the knowledge on the circulation of ZIKV. | Marta Giovanetti Teresa Milano Luiz Carlos Alcantara Laura Carcangiu Eleonora Cella Alessia Lai Alessandra Lo Presti Stefano Pascarella Gianguglielmo Zehender Silvia Angeletti Massimo Ciccozzi | 2016 | Asian Pacific Journal of Tropical Medicine2016，9，5： | 2 |
| 5 | Increased Quality of Life Among Hepatocellular Carcinoma Patients Treated with Radioembolization, Compared with Chemoembolization显示文摘 | Riad Salem Margaret Gilbertsen Zeeshan Butt Khairuddin Memon Michael Vouche Ryan Hickey Talia Baker Michael M. Abecassis Rohi Atassi Ahsun Riaz David Cella James L. Burns Daniel Ganger Al B. Benson Mary F. Mulcahy Laura Kulik Robert Lewandowski | 2013 | Clinical Gastroenterology and Hepatology2013，，： | 2 |
| 6 | Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial显示文摘 | Brian I Rini Bernard Escudier Piotr Tomczak Andrey Kaprin Cezary Szczylik Thomas E Hutson M Dror Michaelson Vera A Gorbunova Martin E Gore Igor G Rusakov Sylvie Negrier Yen-Chuan Ou Daniel Castellano Ho Yeong Lim Hirotsugu Uemura Jamal Tarazi David Cella | 2011 | The Lancet . 2011 (9807)2011，，9807： | 2 |
| 7 | Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial显示文摘 | Brian I Rini Bernard Escudier Piotr Tomczak Andrey Kaprin Cezary Szczylik Thomas E Hutson M Dror Michaelson Vera A Gorbunova Martin E Gore Igor G Rusakov Sylvie Negrier Yen-Chuan Ou Daniel Castellano Ho Yeong Lim Hirotsugu Uemura Jamal Tarazi David Cella | 2011 | The Lancet2011，，9807： | 2 |
| 8 | Neuropathy experienced by colorectal cancer patients receiving oxaliplatin: A qualitative study to validate the Functional Assessment of Cancer Therapy/Gynecologic Oncology Group-Neurotoxicity scale显示文摘BACKGROUND Although oxaliplatin is widely established as a standard treatment in colorectal cancer(CRC),oxaliplatin-induced neuropathy has emerged as a prominent doselimiting side effect associated with quality of life decrements.Ongoing monitoring and management of neuropathy is important for CRC patient quality of life and adherence to treatment.Therefore,a validated self-reported measure of neuropathy would aid in the management and assessment of oxaliplatininduced neuropathy in clinical practice and research.We sought to evaluate the content validity of the 13-item Functional Assessment of Cancer Therapy/Gynecologic Oncology Group-Neurotoxicity subscale(FACT/GOGNtx)for CRC patients receiving oxaliplatin.AIM To understand the neuropathy experiences of CRC patients and assess content validity of the FACT/GOG-Ntx.METHODS Semi-structured concept elicitation and cognitive debriefing interviews were conducted with 31 CRC patients experiencing peripheral neuropathy from current or previous oxaliplatin treatment.Interview data were analyzed using a constant comparative approach,and data were mapped to the FACT/GOG-Ntx to assess content validity.RESULTS Mean age of the sample was 54(range 34-82).The sample was primarily Caucasian(84%)and consisted of nearly equal numbers of men and women.Participants described 28 unique neuropathy symptoms;hand tingling(experienced by 87%of respondents);feet tingling(81%);hand numbness(68%);and feet numbness(84%)were most frequently mentioned.Neuropathy symptoms occurring on the feet were most often identified as most bothersome by participants.Eleven of the 13 FACT/GOG-Ntx items exhibited moderate to strong evidence of content validity.Two items related to trouble hearing and ringing in the ears had weak support;however,these items represent severe neuropathy and could be useful for a patient reported outcome measure.CONCLUSION The FACT/GOG-Ntx represents the key neuropathy experiences of CRC patients treated with oxaliplatin. | Karen Kaiser Madison Lyleroehr Sara Shaunfield Leilani Lacson Maria Corona Sheetal Kircher Malin Nittve David Cella | 2020 | World Journal of Gastrointestinal Oncology2020，12，2： | 2 |
| 9 | Maturation,activation,and protection of dendritic cells induced by double-stranded RNA显示文摘 | Cella M Salio M Sakakibara Y | 1999 | J Exp Med1999，189，5： | 1 |
| 10 | Factors influencing quality of life in cancer patients: anemia and fatigue显示文摘 | Cella D | 1998 | Semin Oncol1998，25，3： | 1 |
| 11 | Detection of deep vein thrombosis in the diagnosis of pulmonary embolism显示文摘 | Sasahara AA Cella G Palla A | 1986 | J Nucl Med Allied Sci1986，30，1： | 1 |
| 12 | Impact of cancer related fatigue on the lives of patients New findings from the Fatigue coalition显示文摘 | Curt G Bteitbart W Cella D | 2000 | The on cologist2000，5，5： | 1 |
| 13 | The functional assessment of Cancer therapy scale:development and validation of the general measure显示文摘 | Cella DF Tulsky DS Gray G | | 0，，3： | 1 |
| 14 | Cutting edge:TREM-2 attenuates macrophage activation显示文摘 | Tumbull IR Gilfillan S Cella M | 2006 | J Immunol2006，177，6： | 1 |
| 15 | NKG2D Recruits Two Distinct Adapters to Trigger NK Cell Activation and Costimulation显示文摘 | Gilfillan S Ho E L Cella M | 2002 | Nat Immunol2002，3，12： | 1 |
| 16 | Serumn leptin concentrations during the menstrual cycle in normal-weight women: Effect of an oral triphasic estrogen-progestin medication 显示文摘 | Giordano G Cordera R | 2000 | Eur J Endocrinol2000，142，： | 1 |
| 17 | Plasma markers of en dothelial dysfunction in pulmonary hypertension显示文摘 | Bellotto F Tona F | 2001 | Chest2001，120，4： | 1 |
| 18 | Phase Ⅲ trial of doxorubicin plus cisplatin with or without paclitaxel plus filgrastim in advanced endometrial carcinoma:a Gynecologic Oncology Group Study显示文摘 | Fleming GF Brunetto VL Cella D | 2004 | J Clin Oncol2004，22，11： | 1 |
| 19 | Measuring health -related quali- ty of life in leukemia : The Functional Assessment of Cancer Therapy - Leukemia( FACT - Leu) questionnaire 显示文摘 | Cella D Jensen SE Webster K | 2012 | Value Heal2012，15，8： | 1 |
| 20 | Impact of cancer-related fatigue on the lives of patients:new findings from the fatigue coalition显示文摘 | Curt GA Breitbart W Cella D | 2000 | The Oncologist2000，5，5： | 1 |
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