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| 1 | Adsorptive hemofiltration for sepsis management: expert recommendations based on the Asia Pacific experience显示文摘To the Editor:In sepsis,bacterial endotoxins play a central role by inducing a dysregulated and exaggerated release of inflammatory mediators and cytokines,often described as the“cytokine storm”or“cytokinemia.”[1]Both endotoxins and cytokines have been implicated in the development of organ dysfunction,including acute kidney injury(AKI).[2]Removing circulating endotoxins and excess cytokines from the circulation restores chemotactic gradients,localizing the immune response to the principal site of infection and re-establishing a regulated immune response.[1,3]Therefore,using hemofilters with enhanced endotoxin and cytokine adsorptive properties may bring about additional therapeutic benefits compared with conventional continuous renal replacement therapy(CRRT)filters. | Ling Zhang Matthew Cove Binh G.Nguyen Nuttha Lumlertgul Kartik Ganesh Alfred Chan Giang T.H.Bui Chunwen Guo Junhua Li Songqiao Liu Mian Peng Kit W.Foong Jian Zhang Minmin Wang Jacques Goldstein Kai Harenski | 2021 | Chinese Medical Journal2021，，18： | 6 |
| 2 | Does diffusion kurtosis imaging lead to better neural tissue characterization? A rodent brain maturation study显示文摘 | Matthew M. Cheung Edward S. Hui Kevin C. Chan Joseph A. Helpern Liqun Qi Ed X. Wu | 2008 | Neuroimage2008，，2： | 2 |
| 3 | Posttraumatic Stress Disorder in Aware Patients from the B-Aware Trial显示文摘 | Kate Leslie Matthew T. V. Chan Paul S. Myles Andrew Forbes Timothy J. McCulloch | 2010 | Anesthesia & Analgesia2010，，3： | 2 |
| 4 | Multiresidue determination of triarylmethane and phenothiazine dyes in fish tissues by LC–MS/MS显示文摘 | Jonathan A. Tarbin Danny Chan George Stubbings Matthew Sharman | 2008 | Analytica Chimica Acta2008，，2： | 2 |
| 5 | Consensus Guidelines for the Management of Postoperative Nausea and Vomiting显示文摘 | Tong J. Gan Pierre Diemunsch Ashraf S. Habib Anthony Kovac Peter Kranke Tricia A. Meyer Mehernoor Watcha Frances Chung Shane Angus Christian C. Apfel Sergio D. Bergese Keith A. Candiotti Matthew TV Chan Peter J. Davis Vallire D. Hooper Sandhya Lagoo-Deena | 2014 | Anesthesia & Analgesia2014，，： | 2 |
| 6 | Fully integrated wearable impedance cytometry platform on flexible circuit board with online smartphone readout显示文摘We present a wearable microfluidic impedance cytometer implemented on a flexible circuit wristband with on-line smartphone readout for portable biomarker counting and analysis.The platform contains a standard polydimethylsiloxane(PDMS)microfluidic channel integrated on a wristband,and the circuitry on the wristband is composed of a custom analog lock-in amplification system,a microcontroller with an 8-bit analog-to-digital converter(ADC),and a Bluetooth module wirelessly paired with a smartphone.The lock-in amplification(LIA)system is implemented with a novel architecture which consists of the lock-in amplifier followed by a high-pass filter stage with DC offset subtraction,and a post-subtraction high gain stage enabling detection of particles as small as 2.8μm using the 8-bit ADC.The Android smartphone application was used to initiate the system and for offline data-plotting and peak counting,and supports online data readout,analysis,and file management.The data is exportable to researchers and medical professionals for in-depth analysis and remote health monitoring.The system,including the microfluidic sensor,microcontroller,and Bluetooth module all fit on the wristband with a footprint of less than 80 cm2.We demonstrate the ability of the system to obtain generalized blood cell counts;however the system can be applied to a wide variety of biomarkers by interchanging the standard microfluidic channel with microfluidic channels designed for biomarker isolation. | Abbas Furniturewalla Matthew Chan Jianye Sui Karan Ahuja Mehdi Javanmard | 2018 | Microsystems & Nanoengineering2018，4，1： | 2 |
| 7 | Brain derived neutrophic factor is produced by skeletal muscle cells in response to contraction and enhances fat oxidation via activation of AMPK显示文摘 | Matthews VB Astr m MB Chan MHS | 2009 | Diabetologia2009，52，： | 1 |
| 8 | Preoperative Ketamine Improves Postoperative Analgesia After Gynecologic Laparoscopic Surgery显示文摘 | Rebecca F. K . Kwok Jean Lim Matthew T.V . Chan Tony Gin Wallace K.Y. Chiu | 2004 | Anesthesia & Analgesia2004，，4： | 1 |
| 9 | Use of Three-Dimensional Speckle-Tracking Echocardiography for Quantitative Assessment of Global Left Ventricular Function: A Comparative Study to Three-Dimensional Echocardiography显示文摘 | Sushil A. Luis Akira Yamada Bijoy K. Khandheria Vicki Speranza Anthony Benjamin Matthew Ischenko David G. Platts Christian R. Hamilton-Craig Luke Haseler Darryl Burstow Jonathan Chan | 2014 | Journal of the American Society of Echocardiography2014，，： | 1 |
| 10 | Brain-derived neu rotrophic factor is produced by skeletal muscle cells in response to contraction and enhances fat oxidation via activation of AMP acti- vated protein kinase显示文摘 | V Matthews M-BAstr6m M H S Chan | 2009 | Diabetologia2009，52，： | 1 |
| 11 | Cytokine gene expression in human skeletal muscle during concentric contraction:evidence that il-8,like il-6,is influenced by glycogen availability显示文摘 | M H STANLEY CHAN ANDREW L CAREY MATTHEW J | 2004 | AM J Physiol Regul Integr Comp Phsiol2004，287，2： | 1 |
| 12 | 猪FGL2基因cDNA末端序列检测及结构分析显示文摘检测猪FGL2基因cDNA末端序列并对该基因结构初步分析。α 32PdCTP放射性同位素标记cDNA探针筛选猪基因组DNA文库;cDNA末端快速扩增(rapidamplificationofcDNAend,RACE)。以猪正常小肠及心脏组织提取新鲜总RNA,反转录后作为模板,设计基因特异性引物,采用Advantage2聚合酶混合物进行PCR扩增;依据猪与人FGL2基因3′端已知同源序列设计PCR上游引物,以人FGL2基因3′末端序列设计下游引物,以猪基因组DNA为模板采用Advantage2聚合酶混合物进行PCR反应;PCR载体重组质粒DNA亚克隆扩增。同位素探针未能筛选到特异阳性克隆,RACE反应检测到特异性转录起始位置及第一个转录终止位置,但仍未检测到第二个转录终止位置。猪基因组DNA行PCR扩增成功检测到猪FGL2基因3′末端未知序列及第二个转录终止位置。 | 刘浩 Anand Ghanekar Matthew Chan Ming Feng Liu 刘永锋 Gary Levy | 2003 | 遗传2003，25，1： | 1 |
| 13 | Diabetes impairs hypothalamo-pituitary-adrenal (HPA) responses to hypoglycemia,and insulin treatment normalizes HPA but not epinephrine responses显示文摘 | Chan O Chan S Inouye K Shum K Matthews SG Vranic M | | 0，，6： | 1 |
| 14 | Diabetes and the hypothalamo-pituitary-adrenal (HPA) axis显示文摘 | Chan O Inouye K Riddell MC Vranic M Matthews SG | | 0，，2： | 1 |
| 15 | The role of renqing in mediating customer relationship investment and relationship commitment in China显示文摘 | Guicheng Shi Yizheng Shi Allan K.K. Chan Matthew Tingchi Liu Kim-Shyan Fam | 2010 | Industrial Marketing Management2010，，4： | 1 |
| 16 | Modulation of HIV-1Replication by a Novel RhoA Effector Activity显示文摘 | Liping Wang Hangchun Zhang Patricia A Solski Matthew J Hart Channing J | 2000 | The Journal of Immunology2000，164，： | 1 |
| 17 | Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance显示文摘 | V. B. Matthews T. L. Allen S. Risis M. H. S. Chan D. C. Henstridge N. Watson L. A. Zaffino J. R. Babb J. Boon P. J. Meikle J. B. Jowett M. J. Watt J.-O. Jansson C. R. Bruce M. A. Febbraio | 2010 | Diabetologia2010，，11： | 1 |
| 18 | A prospective, phase 1/2 study of everolimus and temozolomide in patients with advanced pancreatic neuroendocrine tumor显示文摘 | Jennifer A. Chan Lawrence Blaszkowsky Keith Stuart Andrew X. Zhu Jill Allen Raymond Wadlow David P. Ryan Jeffrey Meyerhardt Marielle Gonzalez Eileen Regan Hui Zheng Matthew H. Kulke | 2013 | Cancer2013，，17： | 1 |
| 19 | Impact of obesity on prostate cancer recurrence after radical prostatectomy: Data from CaPSURE显示文摘 | William W. Bassett Matthew R. Cooperberg Natalia Sadetsky Stefanie Silva Janeen DuChane David J. Pasta June M. Chan Jason W. Anast Peter R. Carroll Christopher J. Kane | 2005 | Urology2005，，5： | 1 |
| 20 | Twin-arginine translocase may have a role in the chaperone function of NarJ from Escherichia coli 显示文摘 | Chan CS Howell JM Matthew L | 2006 | Biochem Biophy Res Commun2006，343，： | 1 |
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