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14篇 您的检索式:作者名="Matthew Bower"
    题名 作者 年代 出处 被引量
1Chemoprotective effects of curcumin in esophageal epithelial cells exposed to bile acids显示文摘AIM:To investigate the ability of curcumin to counteract the impact of bile acids on gene expression of esophageal epithelial cells.METHODS:An esophageal epithelial cell line(HET1A)was treated with curcumin in the presence of deoxycholic acid.Cell proliferation and viability assays were used to establish an appropriate dose range for curcumin.The combined and individual effects of curcumin and bile acid on cyclooxygenase-2(COX-2)and superoxide dismutase(SOD-1 and SOD-2)gene expression were also assessed.RESULTS:Curcumin in a dose range of 10-100μmol/L displayed minimal inhibition of HET-1A cell viability.Deoxycholic acid at a concentration of 200μmol/L caused a 2.4-fold increase in COX-2 gene expression compared to vehicle control.The increased expression of COX-2 induced by deoxycholic acid was partially reversed by the addition of curcumin,and curcumin reduced COX-2 expression 3.3-to 1.3-fold.HET-1A cells exposed to bile acid yielded reduced expression of SOD-1 and SOD-2 genes with the exception that high dose deoxycholic acid at 200μmol/L led to a 3-fold increase in SOD-2 expression.The addition of curcumin treatment partially reversed the bile acid-induced reduction in SOD-1 expression at all concentrations of curcumin tested.CONCLUSION:Curcumin reverses bile acid suppression of gene expression of SOD-1.Curcumin is also able to inhibit bile acid induction of COX-2 gene expression.Matthew R Bower Harini S Aiyer Robert CG Martin Yan Li 2010World Journal of Gastroenterology2010,16,33:10
2Hepatectomy is Superior to Thermal Ablation for Patients with a Solitary Colorectal Liver Metastasis显示文摘Suzanne Claire Schiffman Matthew Bower Russell E. Brown Robert C. G. Martin Kelly M. McMasters Charles R. Scoggins 2010Journal of Gastrointestinal Surgery2010,,12:1
3Nonprotein neurotoxins显示文摘Bower DJ Hart RJ Matthews PA 0,,07:1
4Temozolomide after Radiotherapy for Newly Diagnosed High-grade Glioma and Unfavorable Low-grade Glioma in Children显示文摘Alberto Broniscer Murali Chintagumpala Maryam Fouladi Matthew J. Krasin Mehmet Kocak Daniel C. Bowers Lisa C. Iacono Thomas E. Merchant Clinton F. Stewart Peter J. Houghton Larry E. Kun Davonna Ledet Amar Gajjar 2006Journal of Neuro - Oncology2006,,3:1
5Nonprotein neurotoxins 显示文摘Bower D J Hart R J Matthews P A 1981Clin Toxicol1981,18,7:1
6Changes in acquired immunodeficiency syndrome-related lymphoma since the introduction of highly active antiretroviral therapy显示文摘Matthews GV Bower M Mandalia S 2000{H}Blood2000,,8:1
7Nonprotein neurotoxins显示文摘Bower D J Hart R J Matthews P A 198118(6):8131981,18,6:1
8AIDS related systemic non-Hodgkin's lymphoma 显示文摘Powles T Matthews G Bower M 2000Sex Transm Infect2000,76,5:1
9Mutations in SLC20A2 are a major cause of familial idiopathic basal ganglia calcification显示文摘Sandy Chan Hsu Renee L. Sears Roberta R. Lemos Beatriz Quintáns Alden Huang Elizabeth Spiteri Lisette Nevarez Catherine Mamah Mayana Zatz Kerrie D. Pierce Janice M. Fullerton John C. Adair Jon E. Berner Matthew Bower Henry Brodaty Olga Carmona Valerija Do 2013neurogenetics2013,,1:1
10AIDS related systemic non- Hodgkins lymphoma显示文摘Tom Powles Gaff Matthews Mark Bower 2000Sex Transm Infect2000,76,5:1
11Changes in acquiredimmunodeficiency syndrome-related lymphoma since the introduction of highly active antiretroviral therapy显示文摘Matthews GV Bower M Mandalia S 2000Blood2000,96,8:1
12潮吧——夹缝求生存的创意建筑显示文摘限制有时要比无限的可能性更能激发灵感,下面的这六座建筑就是这样的例子。 倾斜的纽约 雷姆科尔哈斯为纽约东二十二街23号设计的这个建筑被描述为“拥堵文化中的豪华高层公寓”。Matthew Bower Elefen(编译) 2013时代发现2013,,2:0
13The Struvite Precipitation Index:A Practical Framework for Predicting Struvite Supersaturation in Water and Wastewater显示文摘In wastewater facilities, struvite (MgNH4PO4·6H2O) precipitation and subsequent accumulation within sludge processing can be an expensive nuisance or a pathway to orthophosphate reclamation and beneficial reuse. Predictive solubility models developed in the past have been computationally intensive, highly conservative, and have employed uncertain equilibrium constants for the evaluation of solution saturation. The StrPI (Struvite Precipitation Index) developed in this study is a new, computationally light framework for predicting struvite precipitation based on saturation pH. The model permits process-specific calibration (i.e. StrPI plus a correction pH) to deal with the highly variable characteristics of wastewater streams and to eliminate the pH-independent overprediction inherent in existing solubility models. Verification of this model was performed across a range of waste compositions, ionic strengths, and root-mean-square velocity gradients using data from both synthetic laboratory experiments and field tests. The StrPI framework was found to be an effective and uncomplicated predictor of struvite precipitation in both environments.Nathaniel J. Barnes Alan R. Bowers Matthew P. Madolora 2018Journal of Environmental Science and Engineering(A)2018,7,10:0
14Coagulopathy reversal in intracerebral haemorrhage显示文摘As intracerebral hemorrahge becomes more frequent as a result of an aging population with greater comorbidities,rapid identification and reversal of precipitators becomes increasingly paramount.The aformentioned population will ever more likely be on some form of anticoagulant therapy.Understanding the mechanisms of these agents and means by which to reverse them early on is critical in managing the acute intracerebral hemorrhage.Alexander Jacob Sweidan Navneet Kaur Singh Joseph Luke Conovaloff Matthew Bower Leonid I Groysman Mohammad Shafie Wengui Yu 2020Stroke & Vascular Neurology2020,5,1:0
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