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| 1 | DC-derived IL-18 drives Treg differentiation, murine Helicobacter pylori-specific immune tolerance, and asthma protection显示文摘 | Oertli Mathias Sundquist Malin Hitzler Iris Engler Daniela B Arnold Isabelle C Reuter Sebastian Maxeiner Joachim Hansson Malin Taube Christian Quiding-J?rbrink Marianne Müller Anne | 2012 | EN2012，，3： | 5 |
| 2 | Not interferon, but interleukin‐6 controls early gene expression in hepatitis B virus infection显示文摘 | Marianna H?sel Maria Quasdorff Katja Wiegmann Dennis Webb Uta Zedler Mathias Broxtermann Raindy Tedjokusumo Knud Esser Silke Arzberger Carsten J. Kirschning Anja Langenkamp Christine Falk Hildegard Büning Stefan Rose‐John Ulrike Protzer | 2009 | Hepatology2009，，6： | 3 |
| 3 | Analysis of genomic rearrangement and subsequent gene deletion of the attenuated Orf virus strain D1701显示文摘 | Rosita Cottone Mathias Büttner Berthilde Bauer Marco Henkel Eduard Hettich Hanns-Joachim Rziha | 1998 | Virus Research1998，，1： | 3 |
| 4 | Lithium beyond psychiatric indications:the reincarnation of a new old drug显示文摘Lithium has been used in the treatment of bipolar disorders for decades,but the exact mechanisms of action remain elusive to this day.Recent evidence suggests that lithium is critically involved in a variety of signaling pathways affecting apoptosis,inflammation,and neurogenesis,all of which contributing to the complex pathophysiology of various neurological diseases.As a matter of fact,preclinical work reports both acute and longterm neuroprotection in distinct neurological disease models such as Parkinson’s disease,traumatic brain injury,Alzheimer’s disease,and ischemic stroke.Lithium treatment reduces cell injury,decreasesα‑synuclein aggregation and Tau protein phosphorylation,modulates inflammation and even stimulates neuroregeneration under experimental conditions of Parkinson’s disease,traumatic brain injury,and Alzheimer’s disease.The therapeutic impact of lithium under conditions of ischemic stroke was also studied in numerous preclinical in vitro and in vivo studies,giving rise to a randomized double-blind clinical stroke trial.The preclinic data revealed a lithium-induced upregulation of anti-apoptotic proteins such as B-cell lymphoma 2,heat shock protein 70,and activated protein 1,resulting in decreased neuronal cell loss.Lithium,however,does not only yield postischemic neuroprotection but also enhances endogenous neuroregeneration by stimulating neural stem cell proliferation and by regulating distinct signaling pathways such as the RE1-silencing transcription factor.In line with this,lithium treatment has been shown to modulate postischemic cytokine secretion patterns,diminishing microglial activation and stabilizing blood-brain barrier integrity yielding reduced levels of neuroinflammation.The aforementioned observations culminated in a first clinical trial,which revealed an improved motor recovery in patients with cortical stroke after lithium treatment.Beside its well-known psychiatric indications,lithium is thus a promising neuroprotective candidate for the aforementioned neurological diseases.A detailed understanding of the lithium-induced mechanisms,however,is important for prospective clinical trials which may pave the way for a successful benchto-bedside translation in the future.In this review,we will give an overview of lithiuminduced neuroprotective mechanisms under various pathological conditions,with special emphasis on ischemic stroke. | Matteo Haupt Mathias Bähr Thorsten R.Doeppner | 2021 | Neural Regeneration Research2021，16，12： | 2 |
| 5 | 脊髓损伤后残存自主神经功能载录国际标准显示文摘近年来,脊髓损伤神经学分类园际标准(International Stand- ards for the Neurological Classification of Spinal Cord Injury, ISNCSCI)被用来记载脊髓损伤后运动和感觉功能的损害,目前该标准已是第六版。1992年第一份国际认可的标准出版时,曾进行了较大的修订,修订内容包括完全性损伤与不完全性损伤的定义, | MS Alexander AB Jackson W Donovan DE Graves SL Elliott A Krassioukov AW Sheel I Estoresl B Green A Gousse NL Braekett D Cardenas M Kennelly A-K Karlason F Biering-Sorensen K Krogh T Linsenmeyer R Marino J Ditunno CJ Mathias I Perkash G Creasey G Schilero J Wecht B Schurch V Dietz J Sonksen S Stiens D Bodner LA Wuermser J-J Wyndaele 周谋望 刘楠 S Charlifue | 2010 | 中华物理医学与康复杂志2010，32，4： | 2 |
| 6 | Synthesis and characterization of antibacterial and temperature responsive methacrylamide polymers显示文摘 | B Dizman M O Elasri L J Mathias | 2006 | Macromolecules2006，39，： | 1 |
| 7 | Deep intrauterine insemination in sows: first field trial in a USA commercial farm with a newly developed device显示文摘 | Day B N Mathias K Didion B A | 2003 | Theriogenology2003，，59： | 1 |
| 8 | A semi-quantitative RT-PCR method to readily compare expression levels within Botrytis cinerea multigenie families in vitro and in planta显示文摘 | Mathias C Martine B and Anne V C | 2003 | Curr Genet2003，43，1： | 1 |
| 9 | Diagnostic and therapeutic strategies in locally recurrent rectal cancer显示文摘 | Mathias K Hasse FM Theophil B | 2009 | Radiologe2009，32，2： | 1 |
| 10 | Current evidence for transurethral laser therapy of non-muscle invasive bladder cancer 显示文摘 | Mario W K Thorsten B Mathias W | 2011 | World J Urol2011，29，4： | 1 |
| 11 | 显示文摘 | Mathias B T Remeika J | 1951 | Phys Rev1951，82，： | 1 |
| 12 | Electrochemis- try and the future the automobile显示文摘 | Wagner F T Lakshmanan B Mathias M F | 2010 | J Phys Chem Lett2010，1，： | 1 |
| 13 | Synthesis of new hydroxylated monomers based on methacrylate, dimethacrylate, and tetra methacrylate Michael adducts and photopolymerization kinetics of bulk cross-linkers 显示文摘 | Mathias L J Shemper B S Alirol M | 2004 | Macromolecules2004，37，： | 1 |
| 14 | Sorafenib in combination with capecitabine: an oral regimen for patients with HER2-negative locally advanced or metastatic breast cancer 显示文摘 | Baselga J Segalla JG Roch6 H Del Giglio A Pinczowski H Ciruelos EM Filho SC G6mez P Van Eyll B Bermejo B Llombart A Garicochea B Durdn Md Hoff PM Espi6 M de Moraes AA Ribeiro RA Mathias C Gil Gil M Ojeda B Morales J Kwon Ro S Li S Costa F | 2012 | J Clin Oncol2012，30，13： | 1 |
| 15 | Balance in elderly patients:the“get-up and go”test显示文摘 | Mathias S Nayak US Isaacs B | 1986 | Arch Phys Med Rehabil1986，67，： | 1 |
| 16 | Epinephrine Improves 24-Hour Survival in a Swine Model of Prolonged Ventricular Fibrillation Demonstrating that Early Intraosseous Is Superior to Delayed Intravenous Administration显示文摘 | Zuereher Mathias MD Kern Karl B | 2011 | Anesthesia & Analgesia2011，112，4： | 1 |
| 17 | Patterning inconsistencies restrict the true potential of dopaminergic neurons derived from human induced pluripotent stem cells显示文摘Human induced pluripotent stem cells(hiPSCs)are multipotent stem cells genetically reprogrammed using transcription factors,such as Sox2,c-Myc,Oct3/4 and Klf4(Takahashi and Yamanaka,2006)from fibroblasts,derived from either patient or control individuals.These factors are highly expressed in embryonic stem cells,and their overexpression can induce pluripotency in human somatic cells such as fibroblasts.Upon the generation of hiPSCs after reprogramming,these cells can be further differentiated into multiple neuronal cell types by using a strictly designed protocol.This process is known as patterning.Correct use of these hiPSCs derived neurons holds immense potential for researchers to uncover the underpinnings of disease pathophysiology and therefore is considered as a powerful tool. | Sameehan Mahajani Mathias Bähr Sebastian Kügler | 2021 | Neural Regeneration Research2021，16，4： | 1 |
| 18 | Genetic polymorphisms of the T- cell immunoglobulin mucin 1 but not the T-cell immunoglobulin mucin 3 gene are associated with asthma in an Mrican American population显示文摘 | Gao P S Mathias R A Plunkett B | 2005 | J Allergy Clin Immunol2005，115，5： | 1 |
| 19 | Synthesis and antibacterial activities of water-soluble methacrylate polymers containing quaternary ammonium compounds显示文摘 | Dizman B Elasri M O Mathias L J | 2006 | J Polym Sci Pol Chem2006，44，： | 1 |
| 20 | Monitoring survivin expression in cancer: implications for prognosis and therapy显示文摘 | Guindalini R Mathias Machado MC Garicochea B | 2013 | Mol Diagn Ther2013，17，6： | 1 |
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