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368篇 您的检索式:作者名="Lillian"
    题名 作者 年代 出处 被引量
1我国四株狂犬病毒糖蛋白基因序列分析和位点比较显示文摘测定我国人用狂犬疫苗株 (aG)、减毒株 (CTN 181)及两株街毒糖蛋白 (GP)基因cDNA的核苷酸序列及推导氨基酸序列。结果两株街毒仅相差两个碱基和一个氨基酸残基 ;两株街毒与CTN的同源性 (85.9% )高于aG株 (81.9% ) ;聚类分析将街毒和固定毒分为两支。比较GP嗜神经位点的氨基酸序列与蛇神经毒素同AChR结合部位高度同源。被认为决定毒力的 333位Arg ,CTN发生了Q替换 ,其它毒株均为Arg333。所比较的毒株均存在 319位糖基化位点 ,此外 37位糖基化位点也相对保守 ;GP两个主要抗原表位 ,GⅡ的氨基酸构成完全一致 ,GⅢ只在一些减毒株中发生与毒力密切相关碱基的替换。唐青 Lillian A Orciari Charles E.Rupprechti 赵秀芹 李志刚 杨为松 2000中国病毒学2000,15,1:60
2Protective links between vitamin D,inflammatory boweldisease and colon cancer显示文摘Vitamin D deficiency has been associated with a wide range of diseases and multiple forms of cancer including breast, colon, and prostate cancers. Relatively recent work has demonstrated vitamin D to be critical in immune function and therefore important in inflammatory diseases such as inflammatory bowel disease(IBD). Because vitamin D deficiency or insufficiency is increasingly prevalent around the world, with an estimated 30%-50% of children and adults at risk for vitamin D deficiency worldwide, it could have a significant impact on IBD. Epidemiologic studies suggest that low serum vitamin D levels are a risk factor for IBD and colon cancer, and vitamin D supplementation is associated with decreased colitis disease activity and/or alleviated symptoms. Patients diagnosed with IBD have a higher incidence of colorectal cancer than the general population, which supports the notion that inflammation plays a key role in cancer development and underscores the importance of understanding how vitamin D influences inflammation and its cancer-promoting effects. In addition to human epidemiological data, studies utilizing mouse models of colitis have shown that vitamin D is beneficial in preventing or ameliorating inflammation and clinical disease. The precise role of vitamin D on colitis is unknown; however, vitamin D regulates immune cell trafficking and differentiation, gut barrier function and antimicrobial peptide synthesis, all of which may be protective from IBD and colon cancer. Here we focus on effects of vitamin D on inflammation and inflammation-associated colon cancer and discuss the potential use of vitamin D for protection and treatment of IBD and colon cancer.Stacey Meeker Audrey Seamons Lillian Maggio-Price Jisun Paik 2016World Journal of Gastroenterology2016,22,3:15
3How would Capital Account Liberalization Affect China's Capital Flows and the Renminbi Real Exchange Rates?显示文摘在这份报纸,我们学习粗野大写的流动的决定因素,在 2020 投射中国的国际投资位置的尺寸,并且分析为人民币的含意真实汇率如果中国放宽大写的报道。我们在这锻练假设人民币将大部分在当前的十年底完成大写的帐户可改变,与由人们中国的银行的最近的建议一致的一张时间表。我们的分析证明如果大写的帐户被放宽,中国的粗野国际投资位置将显著地成长,并且流入和流出将变得更平衡。私人部门将把它的网络责任位置变成一个平衡位置,并且正式扇区将显著地减少它的网络财产位置,相对这个国家的 GDP。因为私人部门的增加的重要性外国主张和正式外国储备的减少的重要性,中国将能挣更高的网投资收入从在国外。总的来说,中国将继续是一个网债权人,与网是的外国财产位置整个这十年仍然保持大部分稳定的 GDP 的份额。这些调查结果建议真实汇率不是的人民币对大写的流动被期望两方面的大写的帐户自由化特别地敏感。真实汇率将多半作为中国在中等欣赏的一条路径上的人民币被期望维持与它的做贸易的搭挡一起微分的可观的生长。Dong He Lillian Cheung Wenlang Zhang Tommy Wu 2012China & World Economy2012,20,6:13
4Science:'记忆碎片'是真的吗?显示文摘半个多世纪以来,神经学家们一直以为长期记忆是由于多个短期记忆储存起来形成的。而最近一项对记忆形成的神经回路的研究则表明这一说法有可能是错的,因为两种类型的记忆(长期与短期)能够同时产生。这项研究是由来自MIT的研究者们做出。他们参考了此前标记特殊”记忆”细胞的手段,并更进一步地强制性使小鼠对特定的记忆作出反应。并且断开了长期与短期记忆的连接。Takashi Kitamura Mark D. Morrissey Lillian M. Smith Roger L. Redondo 2017现代生物医学进展2017,17,17:11
5Is the feminization of labor harmful to agricultural production? The decision-making and production control perspective显示文摘Even today,academics continue to debate the effect of feminization of agricultural labor force on agricultural output.By considering the dimensions of participation in decision-making and production,this study divides the various agricultural production models into three types:(i)the traditional model of decisions made either jointly by men and women or by men alone while both genders participate in production,(ii)complete feminization of agricultural decision-making and the production labor force,and(iii)feminization of the agricultural production labor force only.This study investigates the effects of combining or separating decision-making and production in regard to agricultural development in the context of feminization of the agricultural labor force.Using follow-up data collected from 2004–2008 by the Ministry of Agriculture of China,we built a comprehensive panel data model to test our hypotheses.Our research shows that in comparison to traditional agricultural households and fully feminized agricultural labor forces,partially feminized production resulted in lower grain yield and technological advancement.The feminization of agricultural labor does not necessarily have a negative impact on agricultural output,especially since heavy manual labor is being increasingly replaced by agricultural machinery and outsourcing of tasks.The degree of feminization of the decision-making and production processes should be an important consideration when evaluating the purported negative effects of the feminization of agricultural labor.LIU Jia-cheng XU Zhi-gang ZHENG Qiu-fen Lillian Hua 2019Journal of Integrative Agriculture2019,18,6:8
6Similar efficacy and safety of tenofovir in Asians and non-Asians with chronic hepatitis B显示文摘AIM:To compare the efficacy and safety of tenofovir disoproxil fumarate(TDF)in Asian and non-Asian chronic hepatitis B(CHB)patients.METHODS:The efficacy and safety of the initial 48wk of treatment with TDF was compared in a posthoc analysis of combined data from 217 Asians and299 non-Asians included in Studies 102 and 103and a post-approval,open-label trial(Study 123).Patient groups were compared according to baseline hepatitis B e antigen(HBe Ag)status and viral load.The main outcome measures included the proportion of patients who achieved a hepatitis B virus(HBV)DNA level<400 copies/m L at Week 48 of treatment.Secondary measures included:HBV DNA and alanine aminotransaminase(ALT)levels over time;proportion of patients with normal ALT levels;proportion of patients with HBe Ag loss/seroconversion and proportion of patients with hepatitis B surface antigen loss/seroconversion;changes in liver histology.Safety and tolerability were evaluated by the occurrence of adverse events(AEs),serious AEs,laboratory abnormalities,discontinuation of the study drug due to AEs,or death.The primary efficacy and safety analysis set included all patients who were randomly assigned to treatment and received at least one dose of study drug.RESULTS:At week 48,similar proportions of Asians and non-Asians reached HBV DNA<400 copies/m L(96%of Asian and 97%of non-Asian patients with HBe Ag-negative CHB and 83%of Asian and 79%of non-Asian patients with HBe Ag-positive CHB had HBV DNA)and normal ALT(78%of Asian and 81%of nonAsian patients with HBe Ag-negative CHB and 71%of Asian and 74%of non-Asian patients with HBe Agpositive CHB had normal ALT).On-treatment HBV DNA decline rates were similar between Asians and nonAsians regardless of baseline HBe Ag status and viralload.HBV DNA decline during the first four weeks was2.9 log10 copies/m L in HBe Ag-negative Asians and nonAsians,and in HBe Ag-positive non-Asians,and 3.1log10 copies/m L in HBe Ag-positive Asians.HBe Ag loss and seroconversion was achieved in 14%of Asians vs 26%and 24%,respectively,in non-Asians.Liver histology improved in 77.2%of Asians and 71.5%of non-Asians.No resistance to TDF developed.No renal safety signals were observed.CONCLUSION:TDF demonstrated similar viral suppression,normalization of ALT,improvements in liver fibrosis,and no detectable resistance in Asian and non-Asian patients regardless of baseline HBe Ag status.Calvin Q Pan Sing Chan Huy Trinh Alan Yao Ho Bae Lillian Lou 2015World Journal of Gastroenterology2015,21,18:4
7本科护理教育自我评价的思路与方法显示文摘目的 通过对本科护理教育自我评价思路和方法的描述,以形成在本科护理教育中自我评价的可行性方案.方法 采用描述性方法, 阐述了护理教育自评方法和思路.结果 明确了本科护理评价的过程和由课程、教师及学生组成的课程评价过程中的3个重要组成部分.陈京立 刘华平 何仲 李峥 Gwen.Sherwood Lillian Eriksen 2005中华护理教育2005,2,4:3
8How Do Delirium and Dementia Increase Length of Stay of Elderly General Medical Inpatients?显示文摘Stephen M. Saravay Michael Kaplowitz John Kurek David Zeman Simcha Pollack Sonia Novik Scott Knowlton Michael Brendel Lillian Hoffman 2011Psychosomatics2011,,3:3
9The inner solar system cratering record and the evolution of impactor populations显示文摘We review previously published and newly obtained crater size-frequency distributions in the inner solar system. These data indicate that the Moon and the terrestrial planets have been bombarded by two populations of objects. Population 1,dominating at early times, had nearly the same size distribution as the present-day asteroid belt, and produced heavily cratered surfaces with a complex, multi-sloped crater size-frequency distribution. Population 2, dominating since about 3.8–3.7 Gyr,had the same size distribution as near-Earth objects(NEOs) and a much lower impact flux, and produced a crater size distribution characterized by a differential –3single-slope power law in the crater diameter range 0.02 km to 100 km. Taken together with the results from a large body of work on age-dating of lunar and meteorite samples and theoretical work in solar system dynamics, a plausible interpretation of these data is as follows. The NEO population is the source of Population 2 and it has been in near-steady state over the past ~ 3.7–3.8 Gyr; these objects are derived from the main asteroid belt by size-dependent non-gravitational effects that favor the ejection of smaller asteroids. However, Population 1 was composed of main belt asteroids ejected from their source region in a size-independent manner, possibly by means of gravitational resonance sweeping during orbit migration of giant planets;this caused the so-called Late Heavy Bombardment(LHB). The LHB began some time before ~3.9 Gyr, peaked and declined rapidly over the next ~ 100 to 300 Myr,and possibly more slowly from about 3.8–3.7 Gyr to ~2 Gyr. A third crater population(Population S) consisted of secondary impact craters that can dominate the cratering record at small diameters.Robert G.Strom Renu Malhotra Zhi-Yong Xiao Takashi Ito Fumi Yoshida Lillian R Ostrach 2015Research in Astronomy and Astrophysics2015,15,3:3
10通过物理教育研究促进物理教学显示文摘本文概述了物理教育研究的内涵以及物理教育研究的方法.通过几何光学教学中的简单例子,阐述了通过物理教育研究促进物理教学的必要性,说明了物理教育研究能够帮助学生学习物理,提高教师教学的有效性,促进教师发展.Lillian C. McDermott 罗莹(编译) 2011物理教师(高中版)2011,,7:2
11A Family of microRNAs Encoded by Myosin Genes Governs Myosin Expression and Muscle Performance显示文摘Eva van Rooij Daniel Quiat Brett A. Johnson Lillian B. Sutherland Xiaoxia Qi James A. Richardson Robert J. Kelm Eric N. Olson 2009Developmental Cell2009,,5:2
12Effect of Lactarius piperatus fruiting body maturity stage on antioxidant activity measured by several biochemical assays显示文摘Lillian Barros Paula Baptista Isabel C.F.R. Ferreira 2007Food and Chemical Toxicology2007,,9:2
13Determinants of job mobility: A theoretical integration and extension显示文摘Thomas W. H.Ng Kelly L.Sorensen Lillian T.Eby Daniel C.Feldman 2010Journal of Occupational and Organizational Psychology2010,,3:2
14Evaluation of asphalt mixture behavior incorporating warm mix additives and reclaimed asphalt pavement显示文摘Incorporation of warm mix asphalt(WMA) and reclaimed asphalt pavement(RAP) has benefited the asphalt industry in many ways such as reducing the demand for virgin materials, lowering energy requirement during the asphalt production and construction, in addition to reducing greenhouse-gas emissions. This study evaluated the effects of Evotherm~ and RH-WMA and RAP on mixtures' behavior in terms of the compaction energy index(CEI), indirect tensile strength(ITS) and resilient modulus. The results showed that warm mix additives reduced the CEI, ITS and resilient modulus; while RAP increased the corresponding values. Statistical analysis showed that mixtures incorporating Evotherm~and RAP had significant effects on CEI, while the effects of RH-WMA on the corresponding value were found to be statistically insignificant. General Linear Model showed that Evotherm~, RAP and RH-WMA exhibited no significant effects on the ITS and resilient modulus. The one-way analysis of variance showed that Evotherm~ influenced mixture behavior significantly, while RAP and RH-WMA effects were found to be statistically insignificant. Regression equations with high accuracy levels were proposed to predict CEI,ITS and resilient modulus with respect to modification of mixture variables such as mix constituents(Evotherm~, RH-WMA, and RAP) and compaction temperature.Seyed Reza Omranian Meor Othman Hamzah Lillian Gungat Sek Yee Teh 2018Journal of Traffic and Transportation Engineering(English Edition)2018,5,3:2
15气候变,农业也变——挪威农业应对气候变化带来的挑战显示文摘气候变化是个全局问题,将牵动社会的各个领域,以粮食生产为核心的农业酋当其冲。毕竟,这关系到国计民生。气候变化带来的挑战极其繁多,而且错综复杂,有时甚至相互抵触。从世界范围来看,气候变化对农业产生的影响,会因为处在不同的地区、面对不同的人群而表现出很大的不同。作为极地国家的挪威,其农业活动也呈现出特有的变化。莉莉莲·艾伊加登(Lillian Oygarden) 尼尔斯·瓦格斯达德(Nils Vagstad) 刘继红·克拉克(Jihong Liu Clarke) 夏建宏(翻译) 2011自然与科技2011,,2:2
16The learning styles and strategies of effective language learners显示文摘Lillian L.C. Wong David Nunan 2011System2011,,2:2
17Guidelines for the prevention of intravascular catheter-related infections显示文摘Naomi P. O’Grady Mary Alexander Lillian A. Burns E. Patchen Dellinger Jeffrey Garland Stephen O. Heard Pamela A. Lipsett Henry Masur Leonard A. Mermel Michele L. Pearson Issam I. Raad Adrienne G. Randolph Mark E. Rupp Sanjay Saint 2011AJIC: American Journal of Infection Control2011,,4:2
18A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance显示文摘Christopher B. Newgard Jie An James R. Bain Michael J. Muehlbauer Robert D. Stevens Lillian F. Lien Andrea M. Haqq Svati H. Shah Michelle Arlotto Cris A. Slentz James Rochon Dianne Gallup Olga Ilkayeva Brett R. Wenner William S. Yancy Howard Eisenson Gera 2009Cell Metabolism2009,,4:2
19Epidermal growth factor receptortargeting in head and neck cancer: have we been juslskimming the surface? 显示文摘Aaron RH Lillian LS 2013Journal of Clinical Oncology2013,,:1
20A finite element of the effects an increasing angle on the tower of Pisa 显示文摘Zbeng Zhou Madara Ogot Lillian Schwartz 2001Finite Element in Analysis and Design2001,,37:1
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