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| 1 | A review of human carcinogens—Part B: biological agents显示文摘 | Véronique Bouvard Robert Baan Kurt Straif Yann Grosse Béatrice Secretan Fatiha El Ghissassi Lamia Benbrahim-Tallaa Neela Guha Crystal Freeman Laurent Galichet Vincent Cogliano | 2009 | Lancet Oncology2009，，4： | 4 |
| 2 | 黑曲霉AS0023果糖转移酶和转化酶催化特性的研究显示文摘研究了在不同蔗糖浓度下从黑曲霉AS0 0 2 3纯化的转化酶 (INV)和果糖转移酶 (FTS)的酶催化活力 ,结果表明 :INV只有水解活性 ,且随着蔗糖浓度的增加酶活力显著下降 ,相反 ,FTS酶活随着蔗糖浓度的增加而增加 ,并且仅催化转果糖基反应 ;用纯化的FTS生产低聚果糖产量可达 6 3% ,应用粗酶制品产量只有 51%。 | Lamia L’Hocine 王璋 江波 | 2000 | 食品与发酵工业2000，26，2： | 4 |
| 3 | Sensory reinnervation of free flaps in reconstruction of the breast and the upper and lower extremities显示文摘There is long-standing debate about sensate versus non-sensate free microvascular flaps among microsurgeons. The principle of connecting not only the vascular supply, but also sensitive nerves, in free tissue transfer is attractive. However, increased operating time and partial spontaneous innervation led to the common decision to restrict microsurgical tissue transfer to the vascular anastomosis and to leave the nerves 'untreated'. Nevertheless, in special cases such as breast reconstruction or extremity reconstruction, the question about sensory nerve coaptation of the flaps remains open. We present our experience with free microvascular tissue transfer for breast and extremity reconstruction and compare the data with previous literature and conclude that most free flap surgeries do not benefit from nerve coaptation. | Nektarios Sinis Androniki Lamia Helml Gudrun Thomas Schoeller Frank Werdin | 2012 | Neural Regeneration Research2012，7，29： | 4 |
| 4 | High level HIV-1 DNA concentrations in brain tissues differentiate patients with post-HAART AIDS dementia complex or cardiovascular disease from those with AIDS显示文摘Highly active antiretroviral treatment(HAART) has had a significant impact on survival of individuals with acquired immunodeficiency syndrome(AIDS);however,with the longer life-span of patients with AIDS,there is increasing prevalence of AIDS dementia complex(ADC) and other non-AIDS-defining illness,and cardiovascular diseases(CVD) are also common.The influence of these varied disease processes on HIV-1 DNA concentration in brain tissues has not been thoroughly assessed in the post-HAART era.The purpose of the current study is to clarify the impacts of ADC and other complications of HIV disease on the viral load in the brains in AIDS patients with post-HARRT.We examined autopsy specimens from the brains of thirteen patients who died from complications of AIDS with quantitative polymerase chain reaction(QPCR).All but one patient had received HAART prior to death since 1995.Two patients died with severe CVD,multiple cerebrovascular atherosclerosis(CVA) throughout the brain and five patients died with ADC.Six patients had no ADC/CVA.A QPCR was used to measure the presence of HIV-1 DNA in six brain tissues(meninges,frontal grey matter,frontal white matter,temporal subcortex,cerebellum and basal ganglia).In the post-HARRT era,for non-ADC/CVA patients,HIV-1 DNA concentration in brain tissues was statistically higher than that in patients with ADC.In a new finding,two patients who suffered from severe CVD,especially CVA,also had high concentrations of HIV-1 in brain compartments not showing ADC related changes.To our knowledge,this is the first report of a relationship between the CVA and HIV-1 viral burden in brain.The current observations suggest that HAART-resistant HIV reservoirs may survive within ADC lesions of the brain as well as the macrophage rich atherosclerosis,which needs to be confirmed by more AIDS cases with CVA. | GALLIGAN Derek C. LAMERS Susanna L. YU Stephanie SHAGRUN Lamia SALEMI Marco MCGRATH Michael S. | 2009 | Science China(Life Sciences)2009，52，7： | 3 |
| 5 | Dual-color deep-tissue three-photon microscopy with a multiband infrared laser显示文摘Multiphoton microscopy combined with genetically encoded fluorescent indicators is a central tool in biology.Threephoton(3P)microscopy with excitation in the short-wavelength infrared(SWIR)water transparency bands at 1.3 and 1.7μm opens up new opportunities for deep-tissue imaging.However,novel strategies are needed to enable in-depth multicolor fluorescence imaging and fully develop such an imaging approach.Here,we report on a novel multiband SWIR source that simultaneously emits ultrashort pulses at 1.3 and 1.7μm that has characteristics optimized for 3P microscopy:sub-70 fs duration,1.25 MHz repetition rate,and μJ-range pulse energy.In turn,we achieve simultaneous 3P excitation of green fluorescent protein(GFP)and red fluorescent proteins(mRFP,mCherry,tdTomato)along with third-harmonic generation.We demonstrate in-depth dual-color 3P imaging in a fixed mouse brain,chick embryo spinal cord,and live adult zebrafish brain,with an improved signal-to-background ratio compared to multicolor twophoton imaging.This development opens the way towards multiparametric imaging deep within scattering tissues. | Khmaies Guesmi Lamiae Abdeladim Samuel Tozer Pierre Mahou Takuma Kumamoto Karolis Jurkus Philippe Rigaud Karine Loulier Nicolas Dray Patrick Georges Marc Hanna Jean Livet Willy Supatto Emmanuel Beaurepaire Frédéric Druon | 2018 | Light(Science & Applications)2018，7，1： | 3 |
| 6 | Isolation and characterization of marine-derived actinomycetes with cytotoxic activity from the Red Sea coast显示文摘Objective: To isolate and evaluate the cytotoxic activity of different actinomycetes species isolated from the Red Sea coast in Sharm el-Sheikh, Egypt.Methods: Forty actinomycetes strains were isolated from different sediments and seawater samples collected from the Red Sea coast in Egypt. Actinomycetes were recognized by morphological and microscopic examinations. Cell viability and cytotoxicity induced by the crude extracts on breast cancer cell lines MDA-MB-231 were assessed using methylene blue assay. The strains with promising cytotoxic activity were identified by sequencing and amplifying the 16 S r RNA genes. The antibacterial activities of the crude extracts were performed using Kirby–Bauer disc diffusion method.Results: The results indicated that five ethyl acetate extracts exhibited cytotoxicity towards breast cancer cell lines MDA-MB-231. The highest cytotoxic activity was found for the ethyl acetate extracts of EGY2 and EGY39. The isolate EGY3 was identified as a new Streptomyces species, while the actinomycete EGY22 was found to be a member of the genus Nocardiopsis sp. The crude extract of the isolate EGY8 showed slightly high antimicrobial activity against different test microorganisms.Conclusions: The results of the present study reveal that marine sediments of the Red Sea are a potent source of novel species of actinomycetes. The isolates may be useful in discovery of novel bioactive compounds and an important step in the development of microbial natural product research. | Mohamed Saleh Abdelfattah Mohammed Ismail Youssef Elmallah Usama Wahid Hawas Lamia Taha Abou El-Kassema Mennat Allah Gamal Eid | 2016 | Asian Pacific Journal of Tropical Biomedicine2016，6，8： | 3 |
| 7 | 国际癌症研究机构工作组乳腺癌筛查简报显示文摘乳腺癌是导致全球女性死亡最常见的恶性肿瘤之一,而且超过一半发生在低至中等收入的国家。近年来在我国,特别是大中城市及沿海经济发展较快地区,乳腺癌已排在女性恶性肿瘤的第一位,是危害妇女健康的主要疾病。如何在早期筛查乳腺癌,以提高防癌效果,对社区及临床有重要意义。本期世界全科医学工作嘹望对2015—06-03在线发表于《新英格兰杂志》的《国际癌症研究机构(IARC)工作组乳腺癌筛查简报》进行了部分翻译,IARC对经乳腺钼靶X线摄影检查筛查乳腺癌的利弊进行了细致评估后,推荐50~69岁女性接受筛查利大于弊。同时,简报还对一般人群及乳腺癌高危人群采取不同方法进行乳腺癌筛查的利弊相关证据评价进行了总结,对全科医生和临床医师筛查工作提供了借鉴。 | Béatrice Lauby-Secretan Chiara Scoccianti Dana Loomis Lamia Benbrahim-Tallaa Véronique Bouvard Franca Bianchini Kurt Straif | 2015 | 中国全科医学2015，18，27： | 2 |
| 8 | Mental health in the post-COVID-19 era:challenges and the way forward显示文摘The COVID-19 pandemic has posed a serious threat to global mental health.Multiple lines of evidence suggest that there is a varying yet considerable increase in mental health issues among the general population and vulnerable groups.12 The aftermath is obscure and speculative from a social,economic,individual and public mental health perspective.Recently published studies support the existence of an emotional epidemic curve,describing a high probability of an increase in the burden of mental health issues in the post-pandemic era.34 Furthermore,previous major public health emergencies showed that more than half of the population devel-oped mental health problems and required mental health intervention.45 There is,therefore,an urgent need to reorganise existing mental health services to address the current unmet needs for mental health and to prepare for future challenges in the postpandemic era in terms of prevention and management. | Ramyadarshni Vadivel Sheikh Shoib Sarah El Halabi Samer El Hayek LamiaàEssam Drita Gashi Bytyçi Ruta Karaliuniene Andre Luiz Schuh Teixeira Sachin Nagendrappa Rodrigo Ramalho Ramdas Ransing Victor Pereira-Sanchez Chonnakarn Jatchavala Frances Nkechi Adiukwu Ganesh Kudva Kundadak | 2021 | General Psychiatry2021，34，1： | 2 |
| 9 | Effects of Nigella sativa on outcome of hepatitis C in Egypt显示文摘AIM: To evaluate the safety, efficacy and tolerability of Nigella sativa (N. sativa ) in patients with hepatitis C not eligible for interferon (IFN)-α. METHODS: Thirty patients with hepatitis C virus (HCV) infection, who were not eligible for IFN/ribavirin therapy, were included in the present study. Inclusion criteria included: patients with HCV with or without cirrhosis, who had a contraindication to IFN-α therapy, or had refused or had a financial constraint to IFN-α therapy. Exclusion criteria included: patients on IFN-α therapy, infection with hepatitis B or hepatitis Ⅰ virus, hepatocellular carcinoma, other malignancies, major severe illness, or treatment non-compliance. Various parameters, including clinical parameters, complete blood count, liver function, renal function, plasma glucose, total antioxidant capacity (TAC), and polymerase chain reaction, were all assessed at baseline and at the end of the study. Clinical assessment included: hepato and/ or splenomegaly, jaundice, palmar erythema, flapping tremors, spider naevi, lower-limb edema, and ascites. N. sativa was administered for three successive months at a dose of (450 mg three times daily). Clinical response and incidence of adverse drug reactions were assessed initially, periodically, and at the end of the study. RESULTS: N. sativa administration significantly improved HCV viral load (380808.7 ± 610937 vs 147028.2 ± 475225.6, P = 0.001) and TAC (1.35 ± 0.5 vs 1.612 ± 0.56, P = 0.001). After N. sativa administration, the following laboratory parameters improved: total protein (7.1 ± 0.7 vs 7.5 ± 0.8, P = 0.001), albumin (3.5 ± 0.87 vs 3.69 ± 0.91, P = 0.008), red blood cell count (4.13 ± 0.9 vs 4.3 ± 0.9, P = 0.001), and platelet count (167.7 ± 91.2 vs 198.5 ± 103, P = 0.004). Fasting blood glucose (104.03 ± 43.42 vs 92.1 ± 31.34, P = 0.001) and postprandial blood glucose (143.67 ± 72.56 vs 112.1 ± 42.9, P = 0.001) were significantly decreased in both diabetic and non-diabetic HCV patients. Patients with lower-limb edema decreased significantly from baseline compared with after treatment [16 (53.30%) vs 7 (23.30%), P = 0.004]. Adverse drug reactions were unremarkable except for a few cases of epigastric pain and hypoglycemia that did not affect patient compliance. CONCLUSION: N. sativa administration in patients with HCV was tolerable, safe, decreased viral load, and improved oxidative stress, clinical condition and glycemic control in diabetic patients. | Eman Mahmoud Fathy Barakat Lamia Mohamed El Wakeel Radwa Samir Hagag | 2013 | World Journal of Gastroenterology2013，19，16： | 2 |
| 10 | Purification and partial characterization of fructosyltransferase and invertase from Aspergillus niger显示文摘 | Lamia L'Hocine Zhang Wang Bo Jiang | 2000 | J Biotechnol2000，81，： | 1 |
| 11 | Towards an aggregation performance measurement system model in a supply chain context 显示文摘 | LAMIA BERRAH VINCENT CLIVILLE | 2007 | Computers in Industry2007，，58： | 1 |
| 12 | Meaning of arterio - venous PCO2 difference in circulatory shock 显示文摘 | Lamia B Monnet X Teboul JL | 2006 | Minerva Anestesiol2006，72，6： | 1 |
| 13 | Bull semen in vitro fertility after cryopreservation using egg yolk LDL: a comparison with Optidyl, a commercial egg yolk extender显示文摘 | Lamia A Daniel T Laetitia J | 2004 | Theriogenology2004，61，： | 1 |
| 14 | Children’s Oncology Group’s 2013 blueprint for research: Behavioral science显示文摘 | Robert B. Noll Sunita K. Patel Leanne Embry Kristina K. Hardy Wendy Pelletier Robert D. Annett Andrea Patenaude E. Anne Lown Stephen A. Sands Lamia P. Barakat | 2012 | Pediatr. Blood Cancer2012，，6： | 1 |
| 15 | Echocardiographic diagnosis of pulmonary artery occlusion pressure elevation during weaning from mechanical ventilation显示文摘 | Lamia B Maizel J Ochagavia A | 2009 | Crit Care Med2009，37，5： | 1 |
| 16 | Short-Term postharvest carbondioxide treatments induce selective molecular and metabolic changes in grape berries显示文摘 | Elisa B Lamia C Pietro T | 2010 | Journal of Agricultural and Food Chemistry2010，58，13： | 1 |
| 17 | Oxaliplatin, Fluorouracil, and leucovorin as adjuvant treatment for colon cancer 显示文摘 | THIERRY A CORRADO B LAMIA M ct al | 2004 | NEC2004，350，23： | 1 |
| 18 | Evaluation of a gas chromatography/mass spectrometry method for the quantification of carboxymethyllysine in food samples显示文摘 | Charissou Lamia Ait-Ameur In'es Birlouez-Aragon | 2007 | Journal of Chromatography A2007，1140，： | 1 |
| 19 | A review of human carcinogens—Part E: tobacco, areca nut, alcohol, coal smoke, and salted fish显示文摘 | Béatrice Secretan Kurt Straif Robert Baan Yann Grosse Fatiha El Ghissassi Véronique Bouvard Lamia Benbrahim-Tallaa Neela Guha Crystal Freeman Laurent Galichet Vincent Cogliano | 2009 | Lancet Oncology2009，，11： | 1 |
| 20 | A method to estimate aquifer artificial recharge from a hill dam in Tunisia显示文摘In arid and semi-arid areas, artificial recharge is a key technology in groundwater resources management, and a reliable estimate of artificial recharge is necessary to its sustainable development. Several methods are available to estimate the artificial recharge; however, most of them require field data or model parameters, thus limiting their applications. To overcome this limitation, we presented an analytical method to estimate the artificial recharge through monitoring the water release by piezometer and analysing the controlling factors of the artificial recharge from a hill dam in Tunisia. A total of 97 measurements of water flow in the streambed recorded from 4 gauging stations were analysed. Results indicated that the average infiltration velocity ranged from 0.043 to 0.127 m/d and the infiltration index varied from 7.6 to 11.8 L/(s·km). Pearson's correlation coefficient analysis shows that the infiltration index, the stream gradient, the thickness of unsaturated zone, the number of infiltration pond, the stream geometry, and the water flow rate were found to be the main factors in determining the infiltration. The high correlation coefficients(0.908 for the number of infiltration pond and 0.999 for the stream geometry) mean that the number of infiltration pond and the stream geometry are the most influential factors. Time variations of groundwater level were used to analyze the recharge effects on the piezometry of aquifer. The analysis showed that during the artificial recharge, the water table increased at a rate of 5 mm/d and that the increase was limited to the area surrounding the recharge site. Based on the results of the study, building infiltration ponds along streambed and improving the potential of rainwater harvesting over the study area are recommended. | Zouheira IBN ALI Ibtissem TRIKI Lamia LAJILI-GHEZAL Moncef ZAIRI | 2017 | Journal of Arid Land2017，9，2： | 1 |
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