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| 1 | 造山型金矿的地质特征和成矿流体显示文摘造山型金矿是全球重要的金矿类型。造山型金矿包含三种类型:产于绿岩带的含金石英碳酸盐脉、产于浊积岩中的含金石英脉和产于条带状铁矿(BIF)中的含金石英脉。造山型金矿的形成受板块构造控制,处于压缩或者转换挤压的造山构造环境。造山型金矿中的绿岩带金矿主要受剪切带、转换断层控制,浊积岩型金矿受褶皱和层间走滑断层控制,而赋存于BIF中的金矿则受剪切带和断层所控制。在这些金矿床中发现了4类流体包裹体:H_2O-CO_2型、富CO_2型、气液包裹体和含Na Cl子矿物的包裹体。所有年代的造山型金矿成矿流体的成分均为低盐度的水溶液和富CO_2的流体,温度在200~400℃范围内。稳定同位素研究表明造山型金矿的成矿流体源自变质流体和岩浆流体。金在成矿流体中的络合物应为Au HS^-或Au H_2S。虽然成矿流体中有丰富的CO_2,但Au在CO_2流体中的溶解度很低,有丰富的CO_2时Au在H_2S中的溶解度增大。流体包裹体研究表明,Au的成矿流体是Na Cl-H_2O-CO_2体系的流体,并在成矿过程中发生了相分离,即Na Cl-H_2O-CO_2流体分成两个流体:H_2O-Na Cl和CO_2-H_2O,Au的沉淀是在这种相分离过程中发生的。 | 卢焕章 池国祥 朱笑青 Guha J Archambault G 王中刚 | 2018 | 大地构造与成矿学2018，42，2： | 36 |
| 2 | 黔西南Au-As-Hg-Tl矿化区毒害金属元素的水地球化学显示文摘研究了黔西南典型 Au-As-Hg-Tl矿化区内毒害金属元素在采矿活动和自然状态影响下的水地球化学特征及其环境效应。结果表明,已开采的 Hg-Tl矿区地下水和地表水中均有很高的毒害金属元素,煤采区地下水中亦表现出类似的特征,而 Hg-Tl矿区外围地下水中金属元素保持在较低的水平。 Hg-Tl矿区地表水中 As和 Tl的分布模式表明,其含量的变化受矿区地下水排泄和尾矿淋滤作用的控制。在尚未开采的金矿区,浅层地下水中金属元素的含量没有明显的富集,尚未构成环境问题。采矿活动扰动下的地下水和暴露于地表的尾矿及矿山废物是水中毒害金属元素的主要来源,水环境研究对采矿活动造成的环境影响具有良好的指示效果。 | 肖唐付 洪业汤 郑宝山 洪冰 Dan Boyle Jayanta Guha | 2000 | 地球化学2000，29，6： | 28 |
| 3 | Antibiotic prophylaxis in variceal hemorrhage:Timing,effectiveness and Clostridium difficile rates显示文摘AIM:To investigate if antibiotics administered within 8 h of endoscopy reduce mortality or increase the incidence of Clostridium difficile infection(CDI).METHODS:A 2-year retrospective analysis of all patients who presented with first variceal hemorrhage was undertaken.The primary outcome measure was 28-d mortality.Secondary outcome measures were 28-d rebleeding rates and 28-d incidence of CDI.All patients were admitted to a tertiary liver unit with a consultantled,24-h endoscopy service.Patients received standard care including terlipressin therapy.Data collection included:primary and secondary outcome measures,timing of first administration of intravenous antibiotics,eti-ology of liver disease,demographics,endoscopy details and complications.A prospective study was undertaken to determine the incidence of CDI in the study population and general medical inpatients admitted for antibiotic therapy of at least 5 d duration.Statistical analysis was undertaken using univariate,non-parametric tests and multivariate logistic regression analysis.RESULTS:There were 70 first presentations of variceal hemorrhage during the study period.Seventy percent of cases were male and 65.7% were due to chronic alcoholic liver disease.In total,64/70(91.4%) patients received antibiotics as prophylaxis during their admission.Specifically,53/70(75.7%) received antibiotics either before endoscopy or within 8 h of endoscopy [peri-endoscopy(8 h) group],whereas 17/70(24.3%) received antibiotics at > 8 h after endoscopy or not at all(non peri-endoscopy group).Overall mortality and rebleeding rates were 13/70(18.6%) and 14/70(20%),respectively.The periendoscopy(8 h) group was significantly less likely to die compared with the non peri-endoscopy group [13.2% vs 35.3%,P = 0.04,odds ratio(OR) = 0.28(0.078-0.997)] and showed a trend towards reduced rebleeding [17.0% vs 29.4%,P = 0.27,OR = 0.49(0.14-1.74)].On univariate analysis,the non peri-endoscopy group [P = 0.02,OR = 3.58(1.00-12.81)],higher model for end-stage liver disease(MELD) score(P = 0.02),presence of hepatorenal syndrome [P < 0.01,OR = 11.25(2.24-56.42)] and suffering a clinical episode of sepsis [P = 0.03,OR = 4.03(1.11-14.58)] were significant predictors of death at 28 d.On multivariate logistic regression analysis,lower MELD score [P = 0.01,OR = 1.16(1.04-1.28)] and periendoscopy(8 h) group [P = 0.01,OR = 0.15(0.03-0.68)] were independent predictors of survival at 28 d.The CDI incidence(5.7%) was comparable to that in the general medical population(5%).CONCLUSION:Antibiotics administered up to 8 h following endoscopy were associated with improved survival at 28 d.CDI incidence was comparable to that in other patient groups. | Matthew RL Brown Graeme Jones Kathryn L Nash Mark Wright Indra Neil Guha | 2010 | World Journal of Gastroenterology2010，16，42： | 13 |
| 4 | 加拿大Abitibi绿岩带Donalda金矿近水平含金石英脉的显微构造分析及其对成矿流体动力学的指示显示文摘位于加拿大Abitibi绿岩带南部的Donalda金矿床主要由近水平的、与剪切带近垂直的含金石英脉组成,矿脉厚度0.3~0.5m,含大量与脉壁平行的条带,指示多期次裂隙扩张和矿物沉淀。原生石英c-轴方位测量显示石英生长方向垂直于脉壁,指示断裂属张性,矿物沉淀属空间充填。显微裂隙、细脉及流体包裹体面(FIPs)的方位测量指示原生矿物受到了近直立的最大主压应力(σ1)作用,与区域性的、近水平的南北向挤压应力不符。这一矛盾现象可用流体压力在超静岩和静水压力之间周期性变化及近水平断裂的周期性张开与闭合来解释。当流体压力大于静岩压力时,断裂张开,原生矿物沉淀,而当流体压力减小时,断裂上盘往下垮,两盘突出的矿物碰撞、碾压形成与脉壁平行的变形条带。由于断裂两盘岩石不是沿整条断裂都互相接触,两盘相顶部分承受的垂直应力大于水平方向的挤压应力,这就解释了为什么显微构造指示近直立的最大主压应力(σ1)。这个流体-构造模式支持断层阀模式,并且无须改变区域应力场就可解释脉体内局部主压应力的变化。 | 池国祥 Jayanta Guha | 2011 | 地学前缘2011，18，5： | 6 |
| 5 | A review of human carcinogens—Part B: biological agents显示文摘 | Véronique Bouvard Robert Baan Kurt Straif Yann Grosse Béatrice Secretan Fatiha El Ghissassi Lamia Benbrahim-Tallaa Neela Guha Crystal Freeman Laurent Galichet Vincent Cogliano | 2009 | Lancet Oncology2009，，4： | 4 |
| 6 | Adjustable Mechanism for Walking Robots with Minimum Number of Actuators显示文摘Recent literature on walking robots deals predominantly with multi-degrees-of-freedom leg mechanisms and machines capable of adopting several gaits.This paper explores the other end of the spectrum suggesting mechanisms derived from a four bar coupler curve for a one degree of freedom walking robot.Simulation of the walk indicates that body of the robot is able to move with low variation in velocity.The best strategy for changing the gait to enable the robot to walk over obstacles and the effect of change in length of different links are explored to open up the possibility of a two degree of freedom walking robot with the capability of changing its gait,suitable as a low cost unit for several applications.Such rugged units would permit the use of an IC engine as the primary source of power and could be of utility in installations where electronics may not be functional.In simple walking machines the foot of a leg is usually required to trace a D shaped curve with respect to the chassis.In this paper we begin with a Hoecken mechanism capable of tracing such a curve.The foot is required to move parallel to itself and the same could be achieved using a six or eight link mechanism.A few such devices have been synthesized in this paper and their motion properties compared.The study also covers the possibility of providing adjustments to vary the step length and height of the foot's movement. | GUHA Anirban AMARNATH C | 2011 | Chinese Journal of Mechanical Engineering2011，24，5： | 4 |
| 7 | Therapeutic Potentials of Oroxylum indicum Bark Extracts显示文摘AIM:Diverse therapeutic potentials of methanolic and aqueous extracts of Oroxylum indicum(L.)Vent.bark,includ- ing antioxidant property,cytotoxicity and protection against oxidative DNA damage were investigated in this study.METHODS:Total phenolics in the extracts were determined by spectrophotometric method.Ferric reducing antioxidant property(FRAP),free radical (DPPH·and ·OH)scavenging activities,as well as inhibitory effect on lipid peroxidation have been investigated.Cytotoxicity of the extracts was investigated by XTT assay in MDA-MB-435S and Hep3B cell lines.Protection of DNA by the extracts against oxidative damage by UV-photolysis of H2O2 was studied.RESULTS:Total phenolic content and inhibition of lipid peroxidation in both extracts were found to be dosage-dependent.Moreover,both extracts exhibited considerable free radical scavenging and ferric reducing abili- ties.The extracts demonstrated extensive cytotoxicity in both tested cell lines,with the methanolic extract showing greater cytotoxic potential.Both extracts exhibited moderate levels of DNA protection against oxidative stress.Total phenolic content was noted to have significant positive correlations with free radical scavenging and reducing power,as well as lipid peroxidation inhibition(P<0.05). CONCLUSIONS:These results indicate that O.indicum bark extracts possess diverse biological activities in vitro and could render itself as a prospective candidate for drug research. | R.Ashok Kumar V.Rajkumar Gunjan Guha Lazar Mathew | 2010 | 中国天然药物2010，8，2： | 4 |
| 8 | Biophysical mechanism-mediated time-dependent effect on sperm of human and monkey vas implanted polyelectrolyte contraceptive显示文摘瞄准:为了在是的精子上决定短、长期的词法效果,由 pH 和电的充电的 intra 管改变导致了。方法:需要的生物物理的影响被精子的可逆抑制的注射在指导(RISUG ) 下面获得进管的腔推迟人的题目和猴子的 ens。RISUG 是苯乙烯的聚合电解质水疗院胶化建筑群缩苹果酸酐(SMA ) 和产生静电的费用并且也在 pH 领域的一个近的空格降低的暗淡乙醇 sulfoxide (DMSO ) 。精子的形态学被轻显微镜学检验,扫描并且传播电子显微镜学。人的学习在注射以后象 3 h 一样早由手淫启用了精液收集,研究延长了直到 6 个月。在猴子,在在 RISUG 培植以后的管切除上,精子特征在连续 sections.Results 被检验:在临床的研究和猴子的组织学的数据的 Semenology 在精子显示出 time-sequencedsperm 血浆膜,尾巴线粒体和原子 decondensation 改变结构的部件,它在 capacitationand 入口期间在精子头和尾巴忍受了显著类似到变化进卵。结论:调查结果提供在精子引起如此的变化的一个工具在原子核被影响以前,禁止使肥沃的能力。没有变成精液的不肥沃的精子引起的 genotoxic 或产生畸形的效果,因此 achievingnon 妨碍的基于管的避孕是可行的。 | Sujoy K. Guha | 2007 | Asian Journal of Andrology2007，9，2： | 4 |
| 9 | 象牙海岸Issia地区铌钽砂矿的研究(英文)显示文摘在西非的象牙海岸Issia地区分布着许多铌钽矿床,包括原生矿和砂矿。原生矿产在分带很好的伟晶岩中。这个地区发育着许多花岗岩和花岗伟晶岩。伟晶岩可分为:(1)分异不好的伟晶岩,无矿化;(2)含Be伟晶岩,分带较好,见绿柱石;(3)含Be-Nb-Ta的伟晶岩,分带很好,是矿体;(4)Be-Nb-Ta-Li伟晶岩,分带很好,是矿体。除了10多个原生矿外,还有许多砂矿。砂矿有两种类型:一种近原生矿的坡积砂矿,另一种是经河流冲刷搬运后的冲积砂矿。我们选择了Etienne-Meguhe砂矿作为近原生矿的坡积砂矿的代表,Bemadi矿作为河流冲积型的砂矿的代表,对这两种类型的砂矿的风化、搬运、沉积机理进行了比较研究。研究发现不同的搬运距离和搬运模式对铌钽砂矿的主要矿物——铌钽铁矿的化学性质没有什么影响,而其物理形态则发生了变化。坡积型砂矿的铌钽铁矿常与石英、长石等矿物连生,其颗粒大小与原生的Nb-Ta伟晶岩中的铌钽铁矿一致;经河流冲积而形成的砂矿中,铌钽铁矿颗粒变小、轮廓变得圆滑,几乎无连生矿物,但矿体集中,常在河流的冲积扇中分布,易开采。 | Benjamin A ALLOU Huanzhang LU Jayanta GUHA Jacques CARIGNAN | 2008 | 大地构造与成矿学2008，32，2： | 3 |
| 10 | Predictors of mortality among HIV-infected patients initiating anti retroviral therapy at a tertiary care hospital in Eastern India显示文摘Objective:To assess early mortality and identify its predictors among the ART naive HIV-infected patients initiating anti retroviral therapy(ART) available free of cost at the ART Centres. Methods:A retrospective cohort analysis of routinely collected programme data was done for assessing mortality of all ART naive adult patients who received first-line ART at a government tertiary care hospital in eastern India during 1st March 2009 and 28th February 2010.Bivariate and multiple regression analyses of the baseline demographic,clinical and laboratory records using SPSS 15.0 were done to identify independent predictors of mortality.Results:The mortality rate at one year was estimated to be 7.66(95%CI 5.84-9.83) deaths/100 patient-years and more than 50%of the deaths occurred during first three months of ART initiation with a median time interval of 73 days.Tuberculosis was the major cause of death.ART naive patients with baseline serum albumin <3.5 mg/dL were eight(OR 7.9;95%CI:3.8-16.5) at risk of death than those with higher serum albumin levels and patients with CD4 count <I00 cells/μL were two times(OR 2.2; 95%CI:1.1-4.4) at risk of death compared to higher CD4 counts.Conclusions:Risk of mortality is increased when ART is initiated at advanced stages of immunosuppression denoted by low serum albumin levels and CD4 cell counts.This highlights the importance of early detection of HIV infection,early management of opportunistic infections including tuberculosis and timely initiation of the antiretroviral drugs in the resource-limited countries,now available free in the Indian national ART programme. | Ananya Bhowmik Subhasis Bhandari Rajyasree De Subhasish Kamal Guha | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，12： | 3 |
| 11 | Experimental and analytical investigation on metal damage suffered from simulated lightning currents显示文摘The damage of two typical metal materials, Al alloy 3003 and steel alloy Q235 B, subjected to four representative lightning current components are investigated by laboratory and analytical studies to provide fundamental data for lightning protection. The four lightning components simulating the natural lightning consist of the first return stroke, the continuing current of interval stroke, the long continuing current, and the subsequent stroke, with amplitudes 200 k A, 8 k A,400 A, and 100 k A, respectively. The damage depth and area suffered from different lightning components are measured by the ultrasonic scanning system. And the temperature rise is measured by the thermal imaging camera. The results show that, for both Al 3003 and steel Q235 B, the first return stroke component results in the largest damage area with damage depth0.02 mm uttermost. The long continuing current component leads to the deepest damage depth of 3.3 mm for Al 3003 and much higher temperature rise than other components. The correlation analysis between damage results and lightning parameters indicates that the damage depth has a positive correlation with charge transfer. The damage area is mainly determined by the current amplitude and the temperature rise increases linearly with the charge transfer larger. | 刘亚坤 傅正财 刘全桢 刘宝全 Anirban GUHA | 2017 | Plasma Science and Technology2017，19，12： | 3 |
| 12 | Diagnostic accuracy of EUS in differentiating mucosal versus submucosal invasion of superficial esophageal cancers: a systematic review and meta-analysis显示文摘 | Nirav Thosani Harvinder Singh Asha Kapadia Nobuo Ochi Jeffrey H. Lee Jaffer Ajani Stephen G. Swisher Wayne L. Hofstetter Sushovan Guha Manoop S. Bhutani | 2012 | Gastrointestinal Endoscopy2012，，2： | 3 |
| 13 | Microstructural analysis of a subhorizontal gold-quartz vein deposit at Donalda,Abitibi greenstone belt,Canada:Implications for hydrodynamic regime and fluid-structural relationship显示文摘The Donalda gold deposit in the southern part of the Archean Abitibi greenstone belt consists mainly of a subhonzontal gold-quartz vein perpendicular to subvertical shear zones.The 0.3—0.5 m thick vein is characterized by vein-parallel banding structures indicating multiple episodes of fracture opening and mineral precipitation.Measurement of the c-axis of primary growth quartz indicates that quartz preferentially grew perpendicular to the fracture,suggesting open space filling and/or extensional nature of the fracture.Measurement of the orientations of microfractures,veinlets and fluid—inclusion planes(FIPs) crosscutting primary growth quartz indicates that the vein minerals were subject to a vertical maximum principal stress(σ_1),which is inconsistent with the subhorizontalσ_1 inferred from the regional stress field with N—S shortening.This apparent discrepancy is explained by invoking episodic fluid pressure fluctuation between supralithostatic and hydrostatic regimes accompanied by episodic opening and closing of the sub-horizontal fracture.When fluid pressure was higher than the lithostatic value,the fracture was opened and primary growth minerals were precipitated,whereas when fluid pressure decreased toward the hydrostatic value,the hanging wall of the fracture collapsed,causing collision of protruding primary growth minerals from both sides of the fracture and resulting in formation of vein-parallel deformation bands.The columns where the two facing sides of the fracture collided were subject to higher-than-lithostatic stress due to the bridging effect and reduced support surface area,explaining the development of verticalσ_1.This hypothesis is consistent the fault-valve model,and explains the flipping ofσ_1 without having to change the regional stress field. | Guoxiang Chi Jayanta Guha | 2011 | Geoscience Frontiers2011，2，4： | 3 |
| 14 | Correlating mode-I fracture toughness and mechanical properties of heat-treated crystalline rocks显示文摘For the effect of thermal treatment on the mode-I fracture toughness(FT), three crystalline rocks(two basalts and one tonalite) were experimentally investigated. Semi-circular bend specimens of the rocks were prepared following the method suggested by the International Society for Rock Mechanics(ISRM)and were treated at various temperatures ranging from room temperature(25 ℃) to 600 ℃. Mode-I FT was correlated with tensile strength(TS), ultrasonic velocities, and Young's modulus(YM). Additionally,petrographic and X-ray diffraction analyses were carried out to find the chemical changes resulting from the heat treatment. Further, scanning electron microscopy(SEM) was conducted to observe the micro structural changes when subjected to high temperatures. These experiments demonstrate that heat treatment has a strong negative impact on the FT and mechanical properties of the rocks. From room temperature to 600 ℃, mode-I FT values of massive basalt, giant plagioclase basalt, and tonalite were reduced by nearly 52%, 68%, and 64%, respectively. Also, at all temperature levels, FT and mechanical properties are found to be exponentially correlated. However, the exact nature of the relationship mainly depends on rock type. Besides, TS was found to be a better indicator of degradation degree than the mode-I FT. SEM images show that micro crack density and structural disintegration of the mineral grains increase with temperature. These physical changes confirm the observed reduction in the stiffness of heat-treated crystalline rocks. | Mayukh Talukdar Debanjan Guha Roy T.N.Singh | 2018 | Journal of Rock Mechanics and Geotechnical Engineering2018，10，1： | 3 |
| 15 | Reduced incidence and mortality from colorectal cancer with flexible-sigmoidoscopy screening: A meta-analysis显示文摘AIM:To conduct a systematic review and meta-analysis of published population-based randomized controlled trials(RCTs).METHODS:RCTs evaluating the difference in mortality and incidence of colorectal cancer(CRC)between a screening flexible sigmoidoscopy(FS)group and control group(not assigned to screening FS)with a minimum 5 years median follow-up were identified by a search of MEDLINE and EMBASE databases and the Cochrane Central Register for Controlled Trials through August 2013.Random effects model was used for meta-analysis.RESULTS:Four RCTs with a total of 165659 patientsin the FS group and 249707 patients in the control group were included in meta-analysis.Intention-totreat analysis showed that there was a 22%risk reduction in total incidence of CRC(RR=0.78,95%CI:0.74-0.83),31%in distal CRC incidence(RR=0.69,95%CI:0.63-0.75),and 9%in proximal CRC incidence(RR=0.91,95%CI:0.83-0.99).Those who underwent screening FS were 18%less likely to be diagnosed with advanced CRC(OR=0.82,95%CI:0.71-0.94).There was a 28%risk reduction in overall CRC mortality(RR=0.72,95%CI:0.65-0.80)and 43%in distal CRC mortality(RR=0.57,95%CI:0.45-0.72).CONCLUSION:This meta-analysis suggests that screening FS can reduce the incidence of proximal and distal CRC and mortality from distal CRC along with reduction in diagnosis of advanced CRC. | Jennifer Shroff Nirav Thosani Sachin Batra Harminder Singh Sushovan Guha | 2014 | World Journal of Gastroenterology2014，20，48： | 3 |
| 16 | Antioxidant and anti-neoplastic activities of Picrorhiza kurroa extracts显示文摘 | V. Rajkumar Gunjan Guha R. Ashok Kumar | 2010 | Food and Chemical Toxicology2010，，2： | 3 |
| 17 | High-throughput design of functional-engineered MXene transistors with low-resistive contacts显示文摘Two-dimensional material-based transistors are being extensively investigated for CMOS(complementary metal oxide semiconductor)technology extension;nevertheless,downscaling appears to be challenging owing to high metal-semiconductor contact resistance.Here,we propose a functional group-engineered monolayer transistor architecture that takes advantage of MXenes’natural material chemistry to offer low-resistive contacts.We design an automated,high-throughput computational pipeline that first performs hybrid density functional theory-based calculations to find 16 sets of complementary transistor configurations by screening more than 23,000 materials from an MXene database and then conducts self-consistent quantum transport calculations to simulate their current-voltage characteristics for channel lengths ranging from 10 nm to 3 nm.Performance of these devices has been found to meet the requirements of the international roadmap for devices and systems(IRDS)for several benchmark metrics(on current,power dissipation,delay,and subthreshold swing).The proposed balanced-mode,functional-engineered MXene transistors may lead to a realistic solution for the sub-decananometer technology scaling by enabling doping-free intrinsically low contact resistance. | Sirsha Guha Arnab Kabiraj Santanu Mahapatra | 2022 | npj Computational Materials2022，，1： | 2 |
| 18 | Aqueous extract of Phyllanthus amarus inhibits chromium(VI)-induced toxicity in MDA-MB-435S cells显示文摘 | Gunjan Guha V. Rajkumar R. Ashok Kumar Lazar Mathew | 2009 | Food and Chemical Toxicology2009，，1： | 2 |
| 19 | Greedy strikes back: Improved facility location algorithms显示文摘 | Guha S Khuller S | 1999 | Journal of Algorithms1999，31，： | 2 |
| 20 | Approximation algorithms for connected dominating sets显示文摘 | Guha S Khuller S | 1998 | Algorithmica1998，20，4： | 2 |
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