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| 1 | BZR1 Positively Regulates Freezing Tolerance via CBF-Dependent and CBF-Independent Pathways in Arabidopsis显示文摘冷应力是不利地影响植物生长和开发的一个主要环境因素。C 重复有约束力的 factor/DRE 绑定因素 1 (CBF/DREB1 ) 规章的串联被显示出在对的植物反应起重要作用的 transcriptional 冷。这里,我们证明发信号的 brassinosteroid (BR ) 的二个关键部件调制 Arabidopsis 植物的结冰忍耐。象 GSK3 一样 kinases 的 loss-of-function 异种在 BR 发信号包含了, bin2-3 bil1 bil2,显示出的增加的结冰公差,而 BIN2 的 overexpression 导致了超敏性到结冰,在 non-acclimated 和 acclimated 下面的应力调节。由对比,显示的抄写因素 BZR1 和 BES1 的 gain-of-function 异种提高了结冰忍耐,和一致地冷的处理能导致 dephosphorylated BZR1 的累积。生物化学、基因的分析证明 BZR1 行动 CBF1 和 CBF2 到在上游直接调整他们的表示。而且,我们发现 BZR1 也调整了另外的英国管基因与 CBF 解开了例如 WKRY6, PYL6, SOC1, JMT,和 SAG21,种反应调制到冷应力。一致地, wrky6 异种显示出减少的结冰忍耐。一起拿,我们的结果显示 BZR1 断然调制通过 CBF 依赖、 CBF 独立的小径冻结忍耐的植物。 | Hui Li Keyi Ye Yiting Shi Jinkui Cheng Xiaoyan Zhang Shuhua Yang | 2017 | Molecular Plant2017，10，4： | 37 |
| 2 | Determining the critical size of a rabbit rib segmental bone defect model显示文摘In order to establish and standardize the rabbit rib segmental bone defect model,it is of vital importance to determine rabbit rib critical size defect(CSD).According to the general time needed for spontaneous long-bone regeneration,three-month observation period was set to determine the CSD.The rabbit rib segmental bone defects with different sizes from 1 to 5cm with or without periosteum were performed in the eighth rib of 4-month-old male New Zealand rabbits and underwent Xray examinations at the 4th,8th and 12th weeks postoperatively.The gross and histological examinations at postoperative week 12 were evaluated,which showed that the critical sizes in the rabbit rib models with and without periosteum were 5 and 2 cm,respectively.This study provides prerequisite data for establishing rabbit rib CSD model and evaluating bonematerials using this model. | Fengzhen Liu Kun Chen Lei Hou Keyi Li Dawei Wang Bin Zhang Xiumei Wang | 2016 | Regenerative Biomaterials2016，3，5： | 2 |
| 3 | Effects of glycerol on apoptotic signaling pathways during boar spermatozoa cryopreservation显示文摘 | Changjun Zeng Keyi Tang Lian He Wenpei Peng Li Ding Donghui Fang Yan Zhang | 2014 | Cryobiology2014，，： | 2 |
| 4 | Incorporating topographic factors in nonlinear mixed-effects models for aboveground biomass of natural Simao pine in Yunnan,China显示文摘A total of 128 Simao pine trees(Pinus kesiya var. langbianensis) from three regions of Pu'er City,Yunnan Province, People's Republic of China, were destructively sampled to obtain tree aboveground biomass(AGB). Tree variables such as diameter at breast height and total height, and topographical factors such as altitude,aspect of slope, and degree of slope were recorded. We considered the region and site quality classes as the random-effects, and the topographic variables as the fixedeffects. We fitted a total of eight models as follows: leastsquares nonlinear models(BM), least-squares nonlinear models with the topographic factors(BMT), nonlinear mixed-effects models with region as single random-effects(NLME-RE), nonlinear mixed-effects models with site as single random-effects(NLME-SE), nonlinear mixed-effects models with the two-level nested region and site random-effects(TLNLME), NLME-RE with the fixed-effects of topographic factors(NLMET-RE), NLME-SE with the fixed-effects of topographic factors(NLMET-SE), and TLNLME with the fixed-effects of topographic factors(TLNLMET). The eight models were compared by modelfitting and prediction statistics. The results showed: model fitting was improved by considering random-effects of region or site, or both. The models with the fixed-effects of topographic factors had better model fitting. According to AIC and BIC, the model fitting was ranked as TLNLME[ NLMET-RE [ NLME-RE [ NLMET-SE [ TLNLMET[ NLME-SE [ BMT [ BM. The differences among these models for model prediction were small. The model prediction was ranked as TLNLME [ NLME-RE [ NLMES E [ N L M E T- R E [ N L M E T- S E [ T L N L M E T [BMT [ BM. However, all eight models had relatively high prediction precision([90 %). Thus, the best model should be chosen based on the available data when using the model to predict individual tree AGB. | Guanglong Ou Junfeng Wang Hui Xu Keyi Chen Haimei Zheng Bo Zhang Xuelian Sun Tingting Xu Yifa Xiao | 2016 | Journal of Forestry Research2016，27，1： | 2 |
| 5 | Mathematical Modeling for On -line Performanee Analysis of Heat Exehange System显示文摘 | Zhou Keyi Zhang Chenyue | 1993 | Science In China1993，36，7： | 1 |
| 6 | Suppression of ETI by PTI priming to balance plant growth and defense through an MPK3/MPK6-WRKYs-PP2Cs module显示文摘Pattern-triggered immunity(PTI)and effector-triggered immunity(ETI)are required for host defense against pathogens.Although PTI and ETI are intimately connected,the underlying molecular mechanisms remain elusive.In this study,we demonstrate that flg22 priming attenuates Pseudomonas syringae pv.tomato DC3000(Pst)AvrRpt2-induced hypersensitive cell death,resistance,and biomass reduction in Arabidopsis.Mitogen-activated protein kinases(MAPKs)are key signaling regulators of PTI and ETI.The absence of MPK3 and MPK6 significantly reduces pre-PTI-mediated ETI suppression(PES).We found that MPK3/MPK6 interact with and phosphorylate the downstream transcription factor WRKY18,which regulates the expression of AP2C1 and PP2C5,two genes encoding protein phosphatases.Furthermore,we observed that the PTI-suppressed ETI-triggered cell death,MAPK activation,and growth retardation are significantly attenuated in wrky18/40/60 and ap2c1 pp2c5 mutants.Taken together,our results suggest that the MPK3/MPK6-WRKYs-PP2Cs module underlies PES and is essential for the maintenance of plant fitness during ETI. | Dacheng Wang Lirong Wei Ting Liu Jinbiao Ma Keyi Huang Huimin Guo Yufen Huang Lei Zhang Jing Zhao Kenichi Tsuda Yiming Wang | 2023 | Molecular Plant2023，16，5： | 1 |
| 7 | Tree-ring δ^(15)N of Qinghai spruce in the central Qilian Mountains of China:Is pre-treatment of wood samples necessary?显示文摘A knowledge of the tree-ring stable nitrogen isotope ratio(δ^(15)N)can deepen our understanding of forest ecosystem dynamics by indicating the long-term availability,cycling and sources of nitrogen(N).However,the radial mobility of N blurs the interannual variations in the long-term N records.Previous studies of the chemical extraction of tree rings before analysis had produced inconsistent results and it is still unclear whether it is necessary to pre-treat wood samples from specific tree species to remove soluble N compounds before determining theδ^(15)N values.We compared the effects of pre-treatment with organic solvents and hot ultrapure water on the N concentration andδ^(15)N of tree rings from endemic Qinghai spruce(Picea crassifolia)growing in the interior of the central Qilian Mountains,China,during the last 60 a.We assessed the effects of different preparation protocols on the removal of the labile N compounds and investigated the need to pre-treat wood samples before determining theδ^(15)N values of tree rings.Increasing trends of the tree-ring N concentration were consistently observed in both the extracted and unextracted wood samples.The total N removed by extraction with organic solvents was about 17.60%,with a significantly higher amount in the sapwood section(P<0.01).Theδ^(15)N values of tree rings decreased consistently from 1960 to 2019 in both the extracted and unextracted wood samples.Extraction with organic solvents increased theδ^(15)N values markedly by about 5.2‰and reduced the variations in theδ^(15)N series.However,extraction with hot ultrapure water had little effect,with only a slight decrease in theδ^(15)N values of about 0.5‰.Our results showed that the radial pattern in the inter-ring movement of N in Qinghai spruce was not minimized by extraction with either organic solvents or hot ultrapure water.It is unnecessary to conduct hot ultrapure water extraction for the wood samples from Qinghai spruce because of its negligible effect on the removal of the labile N.Theδ^(15)N variation trend of tree rings in the unextracted wood samples was not influenced by the heartwood-sapwood transition zone.We suggest that theδ^(15)N values of the unextracted wood samples of the climate-sensitive Qinghai spruce could be used to explore the ecophysiological dynamics while focusing on the long-term variations. | WANG Ziyi LIU Xiaohong WANG Keyi ZENG Xiaomin ZHANG Yu GE Wensen KANG Huhu LU Qiangqiang | 2022 | Journal of Arid Land2022，14，6： | 1 |
| 8 | Dyeing/cross - Linking property of natu- ral iridoids to protein fibers, Part Ⅱ: Color- forming rules and mechanism of methylamine and protein fibers dyed by four natural iridoids 显示文摘 | Zhang Baoqin Xu Loujin Ding Keyi | 2011 | The Journal of the American Leather Chemists Association2011，106，10： | 1 |
| 9 | Influence of driving current' s wave on accelerative per- formance of induction coil launcher显示文摘 | ZHAO KEYI CHENG SHUKANG ZHANG RUIPING | 2008 | IEEE Transactions on Magnetics2008，44，1： | 1 |
| 10 | Advances in chemical synthesis and application of metal-metalloid amorphous alloy nanoparticulate catalysts显示文摘This paper reviews the advances in the chemical synthesis and application of metal-metalloid amorphous alloy nanoparticles consisting of transition metal(M)and metalloid elements(B,P).After a brief introduction on the history of amorphous alloy catalysts,the paper focuses on the properties and characterization of amorphous alloy catalysts,and recent developments in the solution-phase synthesis of amorphous alloy nanoparticles.This paper further outlines the applica-tions of amorphous alloys,with special emphasis on the problems and strategies for the application of amorphous alloy nanoparticles in catalytic reactions. | WU Zhijie LI Wei ZHANG Minghui TAO Keyi | 2007 | Frontiers of Chemical Science and Engineering2007，1，1： | 1 |
| 11 | Dyeing/Cross-Linking Property Of Natural Iridoids To Protein Fibers Part I1 : Color-forming rules and mechanism of methylamine and protein fibers dyed by four natural iridoids 显示文摘 | Zhang BaoQin Xu Loujin Ding Keyi | 2011 | The Journal of the American Leather Chemists Association2011，106，10： | 1 |
| 12 | Catalytic dechlorination of monochlorobenzene with a new type of nanoscale Ni(B)/Fe(B) bimetallic catalytic reductant显示文摘 | Yi Han Wei Li Minghui Zhang Keyi Tao | 2008 | Chemosphere2008，，1： | 1 |
| 13 | Bio-resolution of glycidyl (o, m, p)-methylphenyl ethers by Bacillus megaterium显示文摘 | Zhengfang Zhang Yanming Sheng Keyi Jiang Zhao Wang Yuguo Zheng Qing Zhu | 2010 | Biotechnology Letters2010，，4： | 1 |
| 14 | Nanodiamonds decorated yolk-shell ZnFe_(2)O_(4) sphere as magnetically separable and recyclable composite for boosting antibiotic degradation performance显示文摘Photocatalysis is an environmentally friendly and energy-saving technology, which can effectively remove persistent dangerous pollutants in the water. Pitifully, optical absorption capacity and carrier separation have become major bottlenecks for marvelous photocatalytic performance of photocatalysts.Herein, to address these issue, Nanodiamonds/yolk-shell ZnFe_(2)O_(4) spheres(NDs/ZFO) nanocomposites were successfully constructed via a facile two-step of solvothermal and calcination methods. The synthesized optimal NDs/ZFO-10 nanocomposite exhibits superior photocatalytic degradation activity of antibiotic under visible light, approximately 85% of the total tetracycline(TC) is degraded, and this photocatalyst shows durable cycling stability. This stems from two aspects of refinement: improvement of light absorption capacity and photo-induced charges migration and separation. In addition, the NDs/ZFO composite photocatalyst features excellent magnetic recovery capability, facilitating the recovery of photocatalyst in industry. This study opens a new chapter in the combination of NDs with magnetic materials, and deepens the understanding of the application of NDs modified composite photocatalysts. | Jingjing Pan Haoran Sun Keyi Chen Yuhao Zhang Pengnian Shan Weilong Shi Feng Guo | 2023 | Chinese Journal of Chemical Engineering2023，54，2： | 0 |
| 15 | Metabarcoding of fecal DNA reveals the broad and flexible diet of a globally endangered bird显示文摘Knowing the diet of endangered wild animals is a prerequisite for species-specific conservation and habitat management.The Sichuan partridge Arborophila rufipectus is a globally endangered Galliformes species endemic to the mountains of southwest China.Existing information on the diet of this species is biased and fragmented owing to traditional observation methods.Little is known about their dietary composition or how they respond to temporal variations in food resources throughout the year.In this study,a dietary analysis was performed on 6o fecal samples using DNA Metabarcoding of invertebrates and plants to determine the primary animal and plant components of the diet across 3 critical periods of adult life history(breeding,postbreeding wandering,and overwintering).Preys from the dipteran order,followed by the lepidopteran and ara-neaen spp.,were the predominant,animal-derived foods.Symplocos,Rubus,Celastrus,Holboellia,and Actinidia spp.supply a large abundance of fruits and seeds for this omnivorous bird.Substantial temporal dietary changes among the 3 periods and a general shift toward lower dietary diversity during the breeding season were observed,suggesting that the Sichuan partridge can adjust their diet according to the availability of food resources and their own needs.Characterizing the composition and seasonal changes in Sichuan partridge diets informs the habitat management of native flora(the plant taxa that can generate berries and seeds,such as Symplocos,Rubus,Celastrus,and Holboellia,which are likely of conservation interest)to achieve full life-cycle conservation. | Keyi Tang Yufeng Wang Mengling Wu Shufang Wang Changkun Fu Zhengwang Zhang Yiqiang Fu | 2023 | Current Zoology2023，69，5： | 0 |
| 16 | Mass Spectrometry Analysis of Newly Emerging Coronavirus HCoV-19 Spike Protein and Human ACE2 Reveals Camouflaging Glycans and Unique Post-Translational Modifications显示文摘The coronavirus disease 2019(COVID-19)pandemic has led to worldwide efforts to understand the biological traits of the newly identified human coronavirus(HCoV-19)virus.In this mass spectrometry(MS)-based study,we reveal that out of 21 possible glycosites in the HCoV-19 spike protein(S protein),20 are completely occupied by N-glycans,predominantly of the oligomannose type.All seven glycosylation sites in human angiotensin I converting enzyme 2(hACE2)were found to be completely occupied,mainly by complex N-glycans.However,glycosylation did not directly contribute to the binding affinity between HCoV-19 S protein and hACE2.Additional post-translational modification(PTM)was identified,including multiple methylated sites in both proteins and multiple sites with hydroxylproline in hACE2.Refined structural models of HCoV-19 S protein and hACE2 were built by adding N-glycan and PTMs to recently published cryogenic electron microscopy structures.The PTM and glycan maps of HCoV-19 S protein and hACE2 provide additional structural details for studying the mechanisms underlying host attachment and the immune response of HCoV-19,as well as knowledge for developing desperately needed remedies and vaccines. | Zeyu Sun Keyi Ren Xing Zhang Jinghua Chen Zhengyi Jiang Jing Jiang Feiyang Ji Xiaoxi Ouyang Lanjuan Li | 2021 | Engineering2021，7，10： | 0 |
| 17 | Single-cell transcriptome landscape and antigen receptor dynamic during SARS-CoV-2 vaccination显示文摘Vaccination by inactivated vaccine is an effective strategy to prevent the COVID-19pandemic.However,the detailed molecular immune response at single-cell level is poorly un-derstood.In this study,we systematically delineated the landscape of the pre-and post-vaccination single-cell transcriptome,TCR(T cell antigen receptor)and BCR(B cell antigen re-ceptor)expression profile of vaccinated candidates.The bulk TCR sequencing analysis of COV-ID-19 patients was also performed.Enrichment of a clonal CD8+T cell cluster expressingspecific TCR was identified in both vaccination candidates and COVID-19 patients.These clonalCD8+T cells showed high expression of cytotoxicity,phagosome and antigen presentationrelated genes.The cellecell interaction analysis revealed that monocytes and dendritic cellscould interact with these cells and initiate phagocytosis via ICAM1-ITGAM and ITGB2 signaling.Together,our study systematically deciphered the detailed immunological response duringSARS-CoV-2 vaccination and infection.It may facilitate understanding the immune responseand the T-cell therapy against COVID-19. | Xiaojian Cao Xiaohua Chen Yaqi Zhu Xiaojuan Gou Keyi Yan Bing Yang Dong Men Lei Liu Yong-an Zhang Gang Cao | 2023 | Genes & Diseases2023，10，4： | 0 |
| 18 | Quantum-Inspired Distributed Memetic Algorithm显示文摘This paper proposed a novel distributed memetic evolutionary model,where four modules distributed exploration,intensified exploitation,knowledge transfer,and evolutionary restart are coevolved to maximize their strengths and achieve superior global optimality.Distributed exploration evolves three independent populations by heterogenous operators.Intensified exploitation evolves an external elite archive in parallel with exploration to balance global and local searches.Knowledge transfer is based on a point-ring communication topology to share successful experiences among distinct search agents.Evolutionary restart adopts an adaptive perturbation strategy to control search diversity reasonably.Quantum computation is a newly emerging technique,which has powerful computing power and parallelized ability.Therefore,this paper further fuses quantum mechanisms into the proposed evolutionary model to build a new evolutionary algorithm,referred to as quantum-inspired distributed memetic algorithm(QDMA).In QDMA,individuals are represented by the quantum characteristics and evolved by the quantum-inspired evolutionary optimizers in the quantum hyperspace.The QDMA integrates the superiorities of distributed,memetic,and quantum evolution.Computational experiments are carried out to evaluate the superior performance of QDMA.The results demonstrate the effectiveness of special designs and show that QDMA has greater superiority compared to the compared state-of-the-art algorithms based on Wilcoxon’s rank-sum test.The superiority is attributed not only to good cooperative coevolution of distributed memetic evolutionary model,but also to superior designs of each special component. | Guanghui Zhang Wenjing Ma Keyi Xing Lining Xing Kesheng Wang | 2022 | Complex System Modeling and Simulation2022，2，4： | 0 |
| 19 | Hydrogenation of furfuryl alcohol to tetrahydrofurfuryl alcohol on NiB/SiO_(2) amorphous alloy catalyst显示文摘NiB/SiO2 amorphous alloy catalyst was prepared by power electroless plating method and characterized by induction coupled plasma(ICP),Brunauer–Emmett–Teller method(BET),transmission electron microscope(TEM)and X-ray diffraction(XRD)techniques.The catalytic perfor-mance of NiB/SiO2 was investigated for the hydrogenation of furfuryl alcohol(FA)to tetrahydrofurfuryl alcohol(THFA).The effects of operational conditions,such as reaction tem-perature,pressure,and stirring rate were carefully studied.The proper conditions were determined as the following:pressure 2.0 MPa,temperature 120°C and stirring rate 550 r/min.A typical result with FA conversion of 99%and THFA selectivity of 100%was obtained under such conditions,which was close to that over Raney Ni. | SONG Yun LI Wei ZHANG Minghui TAO Keyi | 2007 | Frontiers of Chemical Science and Engineering2007，1，2： | 0 |
| 20 | An AIE probe for long-term plasma membrane imaging and membrane-targeted photodynamic therapy显示文摘Two red-emissive luminogens(TPTH and TPTB) with typical aggregation-induced emission characteristics were developed. By introducing the heavy atom of Br at the end of alkyl chain, TPTB exhibited higher reactive oxygen species generation efficiency through both types I and II pathways. Due to its excellent biocompatibility and proper lipophilicity, TPTB could be used for long-term cell membrane staining and this staining ability was independent of the change of plasma membrane potential. Furthermore, TPTB could ablate the cancer cells through cell membrane-targeted photodynamic therapy. | Hailing Zhao Nan Li Caixia Ma Zhengwei Wei Qiya Zeng Keyi Zhang Na Zhao Ben Zhong Tang | 2023 | Chinese Chemical Letters2023，34，4： | 0 |
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