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| 1 | Wet and dry deposition fluxes of heavy metals in Pearl River Delta Region(China):Characteristics,ecological risk assessment,and source apportionment显示文摘The atmospheric deposition of heavy metals poses serious risks to the ecological system and human health. To advance our knowledge of atmospheric dry/wet heavy metal deposition in the PRD region, monthly fluxes were examined based on soluble/insoluble fractions of five heavy metal elements(Cu, Pb, Cd, Cr and Zn) in samples collected from January 2014 to December 2015 at Guangzhou(urban) and Dinghushan(suburban) sites. The ratios of wet/dry deposition fluxes indicated that heavy metal deposition was governed by wet deposition rather than dry deposition in the PRD region. Affected by the shifting of the Asian monsoon, wet deposition fluxes exhibited significant seasonal variation between summer monsoon seasons(April to September) and winter monsoon seasons(October to February) in this region. Cd was classified as an extremely strong potential ecological risk based on solubility and the Hakanson ecological risk index. Source contributions to wet deposition were calculated by PMF, suggesting that dust, biomass burning, industries,vehicles, long-range transport and marine aerosol sources in Guangzhou, and Zn fertilizers,marine aerosol sources, agriculture, incense burning, biomass burning, vehicles and the ceramics industry in Dinghushan, were the potential sources of heavy metals. | Lyumeng Ye Minjuan Huang Buqing Zhong Xuemei Wang Qiulan Tu Haoran Sun Chao Wang Luolin Wu Ming Chang | 2018 | Journal of Environmental Sciences2018，30，8： | 20 |
| 2 | The endocrine regulation network of growth hormone synthesis and secretion in fish: Emphasis on the signal integration in somatotropes显示文摘In teleosts, growth hormone (GH) production is governed by multiple neuroendocrine factors from the hypothalamus and other regulators from the pituitary and peripheral organs. Exploring the principles followed by pituitary somatotropes when differentiating and integrating the signals from these regulators at the cellular and intracellular level is essential for understanding the endocrine regulation network of growth hormone synthesis and secretion in fish. This paper discusses recent advances in the action mechanisms of GH regulation factors, including the neuroendocrine regulators, pituitary level factors and peripheral factors, primarily involved in their receptor systems as well as in post-receptor signal transduction pathways. | LI WenSheng & LIN HaoRan State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals and the Guangdong Provincial Key Laboratory for Aquatic Economic Animals, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China | 2010 | Science China(Life Sciences)2010，53，4： | 11 |
| 3 | The interfacial fracture behavior of foam core composite sandwich structures by a viscoelastic cohesive model显示文摘A sandwich beam model consisting of two face sheets and a foam core bonded by a viscoelastic adhesive layer is considered in order to investigate interfacial fracture behavior. Firstly, a cohesive zone model in conjunction with a Maxwell element in parallel, or with a Kelvin element in series, respectively, is employed to describe the characteristics of viscoelasticity for the adhesive layer. The models can be implemented into the implicit finite element code. Next, the parametric study shows that the in- fluences of loading rates on the cohesive zone energy and strength are quite different for different models. Finally, a sandwich double cantilever beam model is adopted to simulate the interface crack growth between the face sheet and core. Numerical examples are presented for various loading rates to demonstrate the efficacy of the rate-dependent cohesive models. | SUN ShiYong CHEN HaoRan | 2011 | Science China(Physics,Mechanics & Astronomy)2011，54，8： | 9 |
| 4 | Genetically optimized on-chip wideband ultracompact reflectors and Fabry–Perot cavities显示文摘Reflectors are an essential component for on-chip integrated photonics. Here, we propose a new method for designing reflectors on the prevalent thin-film-on-insulator platform by using genetic-algorithm optimization.In simulation, the designed reflector with a footprint of only 2.16 μm× 2.16 μm can achieve ~97% reflectivity and 1 dB bandwidth as wide as 220 nm. The structure is composed of randomly distributed pixels and is highly robust against the inevitable corner rounding effect in device fabrication. In experiment, we fabricated on-chip Fabry–Perot(FP) cavities constructed from optimized reflectors. Those FP cavities have intrinsic quality factors of>2000 with the highest value beyond 4000 in a spectral width of 200 nm. The reflectivity fitted from the FP cavity resonances is >85% in the entire wavelength range of 1440–1640 nm and is beyond 95% at some wavelengths.The fabrication processes are CMOS compatible and require only one step of lithography and etch. The devices can be used as a standard module in integrated photonic circuitry for wide applications in on-chip semiconductorlaser structures and optical signal processing. | ZEJIE YU HAORAN CUI XIANKAI SUN | 2017 | Photonics Research2017，5，6： | 7 |
| 5 | Geochronology, Geochemistry, and Hf Isotopic Compositions of Monzogranites and Mafic-Ultramafic Complexes in the Maxingdawannan Area, Eastern Kunlun Orogen, Western China: Implications for Magma Sources, Geodynamic Setting, and Petrogenesis显示文摘This paper presents zircon U-Pb-Hf isotopic compositions and whole-rock geochemical data for monzogranites and mafic-ultramafic complexes of the Maxingdawannan area in the western end of the east Kunlun orogenic belt, western China. The data are used to determine the ages, petrogenesis, magma sources, and geodynamic setting of the studied rocks. U-Pb zircon dating indicates that monzogranites and gabbros of the complexes were emplaced at 399 and 397 Ma, respectively. The monzogranites are shoshonitic, with high SiO2, Al2 O3 and total-alkali contents, and low TFeO, MgO, TiO2 and P2 O5 contents. The mafic-ultramafic complexes are characterized by low Si O2 contents. The monzogranites display enrichment in light rare-earth elements(LREE) and large-ion lithophile elements(LILE), depletion in heavy REEs(HREE) and high-field-strength elements(HFSE), and negative Eu anomalies(Eu/Eu*=0.36–0.48). The mafic-ultramafic complexes are also enriched in LREEs and LILEs, and depleted in HREEs and HFSEs, with weak Eu anomalies(Eu/Eu*=0.84–1.16). Zircon εHf(t) values for the monzogranites and mafic-ultramafic complexes range from-6.68 to 1.11 and-1.81 to 6.29, with zircon model ages of 1 812–1 319 Ma(TDM2) and 1 087–769 Ma(TDM1), respectively. Hf isotopic data indicate that primary magmas of the monzogranites are originated from partial melting of ancient lower crust during the Paleo-Mesoproterozoic, with a juvenile-crust component. Primitive magmas of the mafic-ultramafic complexes are likely originated from a depleted-mantle source modified by slab-derived fluids and contaminated by crustal components. Geochemical data and the geological setting indicate that Devonian intrusions in the Maxingdawannan area are related to northward subduction of the ProtoTethys oceanic lithosphere. | Jiaming Yan Guosheng Sun Fengyue Sun Liang Li Haoran Li Zhenhua Gao Lei Hua Zhengping Yan | 2019 | Journal of Earth Science2019，30，2： | 6 |
| 6 | Is seawater geochemical composition recorded in marine carbonate? Evidence from iron and manganese contents in Late Devonian carbonate rocks显示文摘Iron and manganese are the important redoxsensitive elements in the ocean. Previous studies have established a series of paleo-depositional redox proxies based on the form and content of iron in sedimentary rocks(e.g., degree of pyritization, FeHR/FeT, Fe/Al). These proxies were developed and applied on siliciclastic-rich marine sediments. Although marine carbonate rocks are generally considered to preserve the geochemical signals of ancient seawater, neither Fe nor Mn content in marine carbonate rocks(Fecarb, Mncarb) has been independently used as a proxy to quantify environmental cues in paleo-oceans. Both Fe and Mn are insoluble in oxic conditions(Fe_2O_3, Fe(OH)_3,MnO_2), while their reduced forms(Fe^(2+) and Mn^(2+)) are soluble. Therefore, oxic seawater should have low concentrations of dissolved Fe^(2+)and Mn^(2+), and accordingly carbonate rocks precipitated from oxic seawater should have low Fecarband Mncarb, and vice versa. To evaluate whether Fecarband Mncarbcan be used to quantify oxygen fugacity in seawater, we measured Fecarband Mncarbof Upper Devonian marine carbonate rocks collected from nine sections in South China. Fecarbof intraplatform basin samples wassignificantly higher than that of shelf samples, while shelf and basin samples had comparable Mncarb. The modeling result indicates that the dramatic difference in Fecarbcannot be explained by variation in oxygen fugacity between the shelf and basin seawater. Instead, both Fecarband Mncarb appear to be more sensitive to benthic flux from sediment porewater that is enriched in Fe^(2+)and Mn^(2+). Porewater Fe^(2+)and Mn^(2+)derive from bacterial iron and manganese reduction; flux was controlled by sedimentation rate and the depth of the Fe(Mn) reduction zone in sediments, the latter of which is determined by oxygen fugacity at the water–sediment interface. Thus, high Fecarbof the basin samples might be attributed to low sedimentation rate and/or low oxygen fugacity at the seafloor. However, invariant Mncarbof the shelf and basin samples might be the consequence of complete reduction of Mn in sediments. Our study indicates that marine carbonate rocks may not necessarily record seawater composition, particularly for benthic carbonate rocks. The influence of benthic flux might cause carbonate rocks' geochemical signals to deviate significantly from seawater values. Our study suggests that interpretation of geochemical data from carbonate rocks, including carbonate carbon isotopes, should consider the process of carbonate formation. | Zhe Wang Wen Guo Ting Nie Haoran Ma Tianzheng Huang Yuanlin Sun Bing Shen | 2019 | Acta Geochimica2019，38，2： | 5 |
| 7 | Experimental free-space quantum secure direct communication and its security analysis显示文摘We report an experimental implementation of free-space quantum secure direct communication based on single photons.The quantum communication scheme uses phase encoding,and the asymmetric Mach–Zehnder interferometer is optimized so as to automatically compensate phase drift of the photons during their transitions over the free-space medium.At a 16 MHz pulse repetition frequency,an information transmission rate of 500 bps over a 10 m free space with a mean quantum bit error rate of 0.49%±0.27%is achieved.The security is analyzed under the scenario that Eve performs the collective attack for single-photon state and the photon number splitting attack for multi-photon state in the depolarizing channel.Our results show that quantum secure direct communication is feasible in free space. | DONG PAN ZAISHENG LIN JIAWEI WU HAORAN ZHANG ZHEN SUN DONG RUAN LIUGUO YIN AND GUI LU LONG | 2020 | Photonics Research2020，8，9： | 5 |
| 8 | Bimodular effects of D614G mutation on the spike glycoprotein of SARS-CoV-2 enhance protein processing,membrane fusion,and viral infectivity显示文摘Dear Editor,By the end of June 2020,the pandemic of coronavirus diseases 2019(COVID-19)had resulted in more than 10 million individuals,all over the world,being infected with the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).1 The high contagiousness of SARS-CoV-2 virus was largely attributed to the relatively unique sequence composition in its spike(S)glycoprotein,which is in charge of the host entry by interacting with its cellular receptor angiotensin-converting enzyme 2(ACE2).2,3 The S glycoprotein can be processed into an N terminal S1 fragment that is responsible for receptor binding,and a C terminal S2 fragment that functions to promote membrane fusion.4 SARS-CoV-2 is a type of single-stranded positive-sense ribonucleic acid(RNA)virus,and an increasing number of mutations were identified across the SARS-CoV-2 genome,including the region encoding S glycoprotein.Nevertheless,the functional implications of these mutations remain largely unknown,we here reported the mutation analysis of S gene and a functional exploration of the dominant D614G mutation. | Xiaoyi Jiang Zhengrong Zhang Chenxi Wang Hongguang Ren Lihua Gao Haoran Peng Zubiao Niu He Ren Hongyan Huang Qiang Sun | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 5 |
| 9 | Emerging roles of transforming growth factor β signaling in wet age-related macular degeneration显示文摘Age-related macular degeneration (AMD) is one of the major causes of irreversible blindness among aging populations in developed countries and can be classified as dry or wet according to its progression.Wet AMD,which is characterized by angiogenesis on the choroidal membrane,is uncommonly seen but more severe.Controlling or completely inhibiting the factors that contribute to the progression of events that lead to angiogenesis may be an effective strategy for treating wet AMD.Emerging evidence has shown that transforming growth factor-β(TGF-β) signaling plays a significant role in the progression of wet AMD.In this review,we described the roles of and changes in TGF-β signaling in the development of AMD and discussed the mechanisms of the TGF-β superfamily in choroidal neovascularization (CNV) and wet AMD,including the modulation of angiogenesis-related factors,inflammation,vascular fibrosis,and immune responses,as well as cross-talk with other signaling pathways.These remarkable findings indicate that TGF-β signaling is a potential target for wet AMD treatment. | Kai Wang Haoran Li Ruipu Sun Chaxian Liu Yunfei Luo Shuhua Fu Ying Ying | 2019 | Acta Biochimica et Biophysica Sinica2019，51，1： | 5 |
| 10 | Hexagonal boron nitride nanosheet for effective ambient N2 fixation to NH3显示文摘Industrial production of NH3 from N2 and H2 significantly relies on Haber-Bosch process,which suffers from high energy consume and CO2 emission.As a sustainable and environmentally-benign alternative process,electrochemical artificial N2 fixation at ambient conditions,however,is highly required efficient electrocatalysts.In this study,we demonstrate that hexagonal boron nitride nanosheet (h-BNNS) is able to electrochemically catalyze N2 to NH3.In acidic solution,h-BNNS catalyst attains a high NH3 formation rate of 22.4 μg·h-1·mg-1cat.and a high Faradic efficiency of 4.7% at-0.75 V vs.reversible hydrogen electrode,with excellent stability and durability.Density functional theory calculations reveal that unsaturated boron at the edge site can activate inert N2 molecule and significantly reduce the energy barrier for NH3 fonmation. | Ya Zhang Huitong Du Yongjun Ma Lei Ji Haoran Guo Ziqi Tian Hongyu Chen Hong Huang Guanwei Cui Abdullah M. Asiri Fengli Qu Liang Chen Xuping Sun | 2019 | Nano Research2019，12，4： | 5 |
| 11 | Vesicular Li3V2(PO4)3/C hollow mesoporous microspheres as an efficient cathode material for lithium-ion batteries显示文摘Vesicular lithium vanadium phosphate/carbon hollow mesoporous microspheres were fabricated using a facile polyvinylpyrrolidone-assisted aerosol-spray-assisted method and subsequent heat-treatment. While changing the content of polyvinylpyrrolidone, we found that carbon content was adjustable on the surface of lithium vanadium phosphate. By optimizing the carbon content among the composites, the electrochemical performance can be enhanced significantly. The results of electrochemical performance tests suggested that the samples exhibited good cycle performance and high discharge capability in the voltages between 3.0-4.8 V. The observed excellent electrochemical performances could be attributed to the proper content of carbon coating and the vesicular hollow mesoporous microsphere structure, increasing the transmission rate of lithium ions and reducing the structural change during charging and discharging effectively. | Hongxia Sun Haoran Du Mengkang Yu Kuangfu Huang Nan Yu Baoyou Geng | 2019 | Nano Research2019，12，8： | 4 |
| 12 | Gas template-assisted spray pyrolysis: A facile strategy to produce porous hollow Co3O4 with tunable porosity for high-performance lithium-ion battery anode materials显示文摘 | Haoran Du Kuangfu Huang Min Li Yuanyuan Xia Yixuan Sun Mengkang Yu Baoyou Geng | 2018 | Nano Research2018，11，3： | 4 |
| 13 | Insights into the influence of temperature on the adsorption behavior of sodium oleate and its response to flotation of quartz显示文摘Temperature affects the flotation of quartz in the calcium/sodium oleate(Na OL)system,while there is a lack of understanding of its potential mechanism.Therefore,in this work,the flotation response of quartz to temperature was investigated via micro-flotation experiments,interface property analyses,and theoretical calculations.Flotation results demonstrated that increasing temperature contributed to higher flotation recovery of quartz,which enhanced the removal of quartz from hematite.Surface tension results revealed that higher temperatures lowered the critical micelle concentration(CMC)and surface tension of the Na OL solution,and thus enhanced its surface activity.Solution chemistry calculations and X-ray photoelectron spectroscopy(XPS)measurements confirmed that the increased content of Ca(OH)+achieved by increasing temperatures enhanced the adsorption amounts of calcium species(acting as activation sites)on the quartz surface.Dynamic light scattering(DLS)measurements verified that the association degree of RCOOàto form(RCOO)22àwas strengthened.Furthermore,adsorption density measurements and molecular dynamics(MD)simulations confirmed that increasing the temperature facilitated Na OL adsorption toward the surface of the quartz,which was attributed to the stronger interaction between Na OL and the calcium-activated quartz surface at higher temperatures.As a result,quartz flotation was improved by increasing temperatures.Accordingly,a possible adsorption model was proposed. | Shaohang Cao Wanzhong Yin Bin Yang Zhanglei Zhu Haoran Sun Qiuyue Sheng Keqiang Chen | 2022 | International Journal of Mining Science and Technology2022，32，2： | 4 |
| 14 | Numerical simulation of nonlinear propagation of sound waves in a finite horn显示文摘Nonlinear acoustic propagation generated by a piston in a finite horn is numerically studied.A quasi-one-dimensional nonlinear model with varying cross-section uses high-order low-dispersion numerical schemes to solve the governing equation.Because of the nonlinear wave distortion and reflected sound waves at the mouth,broadband time-domain impedance boundary conditions are employed.The impedance approximation can be optimized to identify the complex-conjugate pole-residue pairs of the impedance functions,which can be calculated by fast and efficient recursive convolution.The numerical results agree very well with experimental data in the situations of weak nonlinear wave propagation in an exponential horn,it is shown that the model can describe the broadband characteristics caused by nonlinear distortion.Moreover,finite-amplitude acoustic propagation in types of horns is simulated,including hyperbolic,conical,exponential and sinusoidal horns.It is found that sound pressure levels at the horn mouth are strongly affected by the horn profiles,the driving velocity and frequency of the piston.The paper also discusses the influence of the horn geometry on nonlinear waveform distortion. | HOU Wei PAN Haoran SONG Weihua JING Xiaodong SUN Xiaofeng | 2015 | Chinese Journal of Acoustics2015，34，2： | 4 |
| 15 | Aberrant cholesterol metabolic signaling impairs antitumor immunosurveillance through natural killer T cell dysfunction in obese liver显示文摘Obesity is a major risk factor for cancers including hepatocellular carcinoma(HCC)that develops from a background of non-alcoholic fatty liver disease(NAFLD).Hypercholesterolemia is a common comorbidity of obesity.Although cholesterol biosynthesis mainly occurs in the liver,its role in HCC development of obese people remains obscure.Using high-fat high-carbohydrate diet-associated orthotopic and spontaneous NAFLD-HCC mouse models,we found that hepatic cholesterol accumulation in obesity selectively suppressed natural killer T(NKT)cell-mediated antitumor immunosurveillance.Transcriptome analysis of human liver revealed aberrant cholesterol metabolism and NKT cell dysfunction in NAFLD patients.Notably,cholesterol-lowering rosuvastatin restored NKT expansion and cytotoxicity to prevent obesogenic diet-promoted HCC development.Moreover,suppression of hepatic cholesterol biosynthesis by a mammalian target of rapamycin(mTOR)inhibitor vistusertib preceded tumor regression,which was abolished by NKT inactivation but not CD8^(+)T cell depletion.Mechanistically,sterol regulatory element-binding protein 2(SREBP2)-driven excessive cholesterol production from hepatocytes induced lipid peroxide accumulation and deficient cytotoxicity in NKT cells,which were supported by findings in people with obesity,NAFLD and NAFLD-HCC.This study highlights mTORC1/SREBP2/cholesterol-mediated NKT dysfunction in the tumor-promoting NAFLD liver microenvironment,providing intervention strategies that invigorating NKT cells to control HCC in the obesity epidemic. | Wenshu Tang Jingying Zhou Weiqin Yang Yu Feng Haoran Wu Myth T.S.Mok Lingyun Zhang Zhixian Liang Xiaoyu Liu Zhewen Xiong Xuezhen Zeng Jing Wang Jiahuan Lu Jingqing Li Hanyong Sun Xiaoyu Tian Philip Chun Yeung Yong Hou Heung Man Lee Candice C.H.Lam Howard H.W.Leung Anthony W.H.Chan Ka Fai To John Wong Paul B.S.Lai Kelvin K.C.Ng Simon K.H.Wong Vincent W.S.Wong Alice P.S.Kong Joseph J.Y.Sung Alfred S.L.Cheng | 2022 | Cellular & Molecular Immunology2022，19，7： | 3 |
| 16 | Heterogeneous Mg isotopic composition of the early Carboniferous limestone: implications for carbonate as a seawater archive显示文摘Carbonate precipitation and hydrothermal reaction are the two major processes that remove Mg from seawater.Mg isotopes are significantly(up to 5%)fractionated during carbonate precipitation by preferential incorporation of ^(24)Mg,while hydrothermal reactions are associated with negligible Mg isotope fractionation by preferential sequestration of^( 26)Mg.Thus,the marine Mg cycle could be reflected by seawater Mg isotopic composition(δ^(26)Mg_(sw)),which might be recorded in marine carbonate.However,carbonates are both texturally and compositionally heterogeneous,and it is unclear which carbonate component is the most reliable for reconstructing δ^(26)Mg_(sw).In this study,we measured Mg isotopic compositions of limestone samples collected from the early Carboniferous Huangjin Formation in South China.Based on petrographic studies,four carbonate components were recognized:micrite,marine cement,brachiopod shell,and mixture.The four components had distinct δ^(26)Mg:(1)micrite samples ranged from -2.86% to -2.97%;(2)pure marine cements varied from -3.40% to -3.54%,while impure cement samples containing small amount of Rugosa coral skeletons showed a wider range(-3.27% to-3.75%);(3)values for the mixture component were-3.17% and -3.49%;and (4)brachiopod shells ranged from -2.20% to -3.07%,with the thickened hinge area enriched in ^( 24)Mg.Due to having multiple carbonate sources,neither the micrite nor the mixture component could be used to reconstruct δ^(26)Mg_(sw).In addition,the marine cement was homogenous in Mg isotopes,but lacking the fractionation by inorganic carbonate precipitation that is prerequisite for the accurate determination of δ^(26)Mg_(sw).Furthermore,brachiopod shells had heterogeneous C and Mg isotopes,suggesting a significant vital effect during growth.Overall,the heterogeneous δ^(26)Mg of the Huangjin limestone makes it difficult to reconstruct δ^(26)Mg_(sw)using bulk carbonate/calcareous sediments.Finally,δ^(26)Mg_(sw)was only slightly affected by the faunal composition of carbonate-secreting organisms,even though biogenic carbonate accounts for more than 90% of marine carbonate production in Phanerozoic oceans and there is a wide range(0.2%–4.8%)of fractionation during biogenic carbonate formation. | Haoran Ma Yihe Xu Kangjun Huang Yuanlin Sun Shan Ke Yang Peng Xianguo Lang Zhen Yan Bing Shen | 2018 | Acta Geochimica2018，37，1： | 3 |
| 17 | Realization of quantum secure direct communication over 100 km fiber with time-bin and phase quantum states显示文摘Rapid progress has been made in quantum secure direct communication in recent years.For practical application,it is important to improve the performances,such as the secure information rate and the communication distance.In this paper,we report an elaborate physical system design and protocol with much enhanced performance.This design increased the secrecy capacity greatly by achieving an ultra-low quantum bit error rate of<0.1%,one order of magnitude smaller than that of existing systems.Compared to previous systems,the proposed scheme uses photonic time-bin and phase states,operating at 50 MHz of repetition rate,which can be easily upgraded to over 1 GHz using current on-the-shelf technology.The results of our experimentation demonstrate that the proposed system can tolerate more channel loss,from 5.1 dB,which is about 28.3 km in fiber in the previous scheme,to 18.4 dB,which corresponds to fiber length of 102.2 km.Thus,the experiment shows that intercity quantum secure direct communication through fiber is feasible with present-day technology. | Haoran Zhang Zhen Sun Ruoyang Qi Liuguo Yin Gui-Lu Long Jianhua Lu | 2022 | Light(Science & Applications)2022，11，5： | 2 |
| 18 | Grading of uterine cervical cancer by using the ADC difference value and its correlation with microvascular density and vascular endothelial growth factor显示文摘 | Ying Liu Zhaoxiang Ye Haoran Sun Renju Bai | 2013 | European Radiology2013，，3： | 2 |
| 19 | Temperature dependence of densities of Sb and Bi melts显示文摘The densities of Sb and Bi melts were investigated by an improved Archimedean method. The results show that the density of the Sb melt decreases linearly with increasing temperature,but the density of the Bi melt firstly increases and then decreases as the temperature increases. There is a maximum density value of 10.002 g/cm3 at 310 ℃ ,about 39℃ above the melting point. The temperature depend-ence of the Sb melt is well fitted with the expression ρ =6.8590-5.8105×10-4T,and that of the Bi melt is fitted with ρ =10.3312-1.18×10-3T. The results were discussed from a microstructure viewpoint. | GENG HaoRan SUN ChunJing WANG Rui QI XiaoGang ZHANG Ning | 2007 | Chinese Science Bulletin2007，52，15： | 2 |
| 20 | Genome-wide analysis of NDR1/HIN1-like genes in pepper(Capsicum annuum L.)and functional characterization of CaNHL4 under biotic and abiotic stresses显示文摘Plant NDR1/HIN1-like(NHL)genes play an important role in triggering plant defenses in response to biotic stresses.In this study,we performed a genome-wide identification of the NHL genes in pepper(Capsicum annuum L.)and characterized the functional roles of these CaNHL genes in response to abiotic stresses and infection by different pathogens.Phylogenetic analysis revealed that CaNHLs can be classified into five distinct subgroups,with each group containing generic and specific motifs.Regulatory element analysis showed that the majority of the promoter regions of the identified CaNHLs contain jasmonic acid(JA)-responsive and salicylic acid(SA)-responsive elements,and transcriptomic analysis revealed that CaNHL genes are expressed in all the examined tissues of pepper.The CaNHL1,CaNHL4,CaNHL6,CaNHL10,CaNHL11,and CaNHL12 genes were significantly upregulated under abiotic stress as well as in response to different pathogens,such as TMV,Phytophthora capsici and Pseudomonas syringae.In addition,we found that CaNHL4 localizes to the plasma membrane.CaNHL4-silenced pepper plants display significantly increased susceptibility to TMV,Phytophthora capsici and Pseudomonas syringae,exhibiting reduced expression of JA-related and SA-related genes and reduced ROS production.However,transient overexpression of CaNHL4 in pepper increases the expression of JArelated and SA-related genes,enhances the accumulation of ROS,and inhibits the infection of these three pathogens.Collectively,for the first time,we identified the NHL genes in pepper and demonstrated that CaNHL4 is involved in the production of ROS and that it also regulates the expression of JA-related and SA-related genes in response to different pathogens,suggesting that members of the CaNHL family play an essential role in the disease resistance of pepper. | Changyun Liu Haoran Peng Xinyu Li Chaolong Liu Xing Lv Xuefeng Wei Aihong Zou Jian Zhang Guangjin Fan Guanhua Ma Lisong Ma Xianchao Sun | 2020 | Horticulture Research2020，7，1： | 2 |
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