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| 1 | 美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。 | Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) | 2012 | 中华神经科杂志2012，45，5： | 22 |
| 2 | Novel proteasome inhibitors to overcome bortezomib resistance显示文摘 | Ruschak AM Slassi M Kay LE | 2011 | J Natl Cancer Inst2011，103，13： | 1 |
| 3 | Tissue selec tive action of tamoxifen methiodide,raloxifene and tamoxifen on creatine kinas e B activity in vitro and in vivo显示文摘 | Waisman A Kaye AM | 1996 | J Steroid Biochem Mol Biol1996，59，56： | 1 |
| 4 | Rhabdomyolysis: Pathogenesis ,Diagnosis ,and Treatment 显示文摘 | Torres PA Helmstetter JA Kaye AM | 2015 | OchSner J2015，15，1： | 1 |
| 5 | Predominant TH2 - like bronchoalveolar T- lymphocyte population in atopic asthma显示文摘 | Robinson DS Hamid Q Ying S Tsicopoulos A Barkans J Bentley AM Corrigan C Durham SR Kay AB | 1992 | N Engl J Med1992，326，： | 1 |
| 6 | Rhabdomyoly- sis: pathogenesis, diagnosis, and treatment显示文摘 | Torres PA Helmstetter JA Kaye AM | 2015 | Ochsner J2015，15，： | 1 |
| 7 | The prism bar-Prentice and frontal positions显示文摘 | Kaye SB Ansons AM Green JR | 1989 | Eye1989，3，： | 1 |
| 8 | Stimulation of protein synthesis and expansion of pig blastocysts by insulin in vitro显示文摘 | Lewis AM Kaye PL Lising R | 1992 | Reprod Fertil Dev1992，4，1： | 1 |
| 9 | Rapid detection of mecA and nucgenes in staphylococci by real-time multiplex polymerase chain re-action显示文摘 | Costa AM kay I Palladino | 2005 | Diagn Microbiol Infect Dis2005，51，1： | 1 |
| 10 | Evaluation of ultra- sound-guided radial artery cannulation in children 显示文摘 | Ganesh A Kaye R Cahill AM | 2009 | Pediatr Crit Care Med2009，10，： | 1 |
| 11 | Does double row rotator cuff repair improve functional outcome of patients compared with single-row technique? A systematic review显示文摘 | DeHaan AM Axelrad TW Kaye E | | 0，，05： | 1 |
| 12 | Does double-row rotator cuff repair improve functional outcome of patients compared with single-row technique?A systematic review显示文摘 | DeHaan AM Axelrad TW Kaye E | | 0，，05： | 1 |
| 13 | A further look at tricuspid annuloplasty显示文摘 | Mendez AM Zubiate P | 1976 | Ann Thorac Surg1976，22，5： | 1 |
| 14 | Anfiadrenergic effect of chronic amiodarone therapy in human heart failure显示文摘 | Kaye DM Dart AM Jennings GL | 1999 | J Am Coll Cardiol1999，33，6： | 1 |
| 15 | Transgluteal approach for draining pelvic fluid collections in pediatric patients显示文摘 | Caltill AM Baskin KM Kaye RD | 2005 | Radiology2005，234，3： | 1 |
| 16 | Rhabdomyolysis : path- ogenesis, diagnosis, and treatment 显示文摘 | Torres PA Helmstetter JA Kaye AM | 2015 | Ochsner J2015，15，1： | 1 |
| 17 | CT - guided percutaneous lung biopsy in children 显示文摘 | Cahill AM Baskin KM Kaye RD | 2004 | J Vase Interv Radiol2004，15，9： | 1 |
| 18 | Impaired inhibitory control is associated with higher-order repetitive behaviors in autism spectrum disorders显示文摘 | Mosconi MW Kay M D'Cruz AM | 2009 | Psychol Med2009，39，9： | 1 |
| 19 | Tramadol, pharmacolo- gy, side effects, and serotonin syndrome: a review 显示文摘 | BEAKLEY BD KAYE AM KAYE AD | 2015 | Pain Physician2015，18，4： | 1 |
| 20 | Does double-row rotator cuff repair improve functional outcome of patients compared with sin- gle-row technique? A systematic review显示文摘 | De Haan AM Axelrad TW Kaye E | 2012 | Am J Sports Med2012，40，： | 1 |
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