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| 1 | Hand bone mass in rheumatoid arthritis:A review of the literature显示文摘Rheumatoid arthritis(RA) is a common chronic inflammatory disease and periarticular osteoporosis or osteopenia of the inflamed hand joints is an early feature of RA Quantitative measurement of hand bone loss may be an outcome measure for the detection of joint destruction and disease progression in early RA. This systematic review examines the published literature reporting hand bone mass in patients with RA, particularly those using the dual X-ray absorptiometry(DXA) methods The majority of the studies reported that hand bone loss is associated with disease activity, functional statusand radiological progression in early RA. Quantitative measurement of hand bone mineral density by DXA may be a useful and practical outcome measure in RA and may be predictive for radiographic progression or functional status in patients with early RA. | Gamze Kilic Salih Ozgocmen | 2015 | World Journal of Orthopedics2015，6，1： | 18 |
| 2 | Tensile and Spring-Back Behavior of DP600 Advanced High Strength Steel at Warm Temperatures显示文摘In recent years,the use of advanced high strength steels in automotive industry has been increased remarkably.Among advanced high strength steels,dual phase(DP) steels have gained a great attention owing to a combination of high strength and good formability.However,high strength usually increases the spring-back behavior of the material,which creates problems for the parts during the assembly.Thus,the uniaxial tensile deformation and spring-back behaviors of DP600 advanced high strength steel were investigated in rolling(0°),diagonal(45°),and transverse(90°) directions in the temperature range from room temperature(RT) to 300 ℃.All tests were performed at a deformation speed of 25 mm/min.A V-shaped die(60°) was used for the spring-back measurements.The results indicated that the formability and spring-back of the material were decreased with increasing the temperatures.The material showed complex behaviors in different directions and at different temperatures. | F Ozturk S Toros S Kilic | 2009 | Journal of Iron and Steel Research(International)2009，16，6： | 17 |
| 3 | Current adjuvant treatment modalities for gastric cancer:From history to the future显示文摘The discrepancy between the surgical technique and the type of adjuvant chemotherapy used in clinical trials and patient outcomes in terms of overall survival rates has led to the generation of different adjuvant treatment protocols in distinct parts of the world.The adjuvant treatment recommendation is generally chemoradiotherapy in the United States,perioperative chemotherapy in the United Kingdom and parts of Europe,and chemotherapy in Asia.These options mainly rely on the United States Intergroup-0116,United Kingdom British Medical Research Council Adjuvant Gastric Infusional Chemotherapy,and the Asian Adjuvant Chemotherapy Trial of S-1 for Gastric Cancer and Capecitabine and Oxaliplatin Adjuvant Study in Stomach Cancer trials.However,the benefits were evident for only certain patients,which were not very homogeneous regarding the type of surgery,chemotherapy regimens,and stage of disease.Whether the dissimilarities in survival are attributable to surgical technique or intrinsic biological differences is a subject of debate.Regardless of the extent of surgery,multimodal therapy may offer modest survival advantage at least for diseases with lymph node involvement.Moreover,in the era of individualized treatment for most of the other cancer types,identification of special subgroups comprising those who will derive more or no benefit from adjuvant therapy merits further investigation.The aim of this review is to reveal the historical evolution and future reflections of adjuvant treatment modalities for resected gastric cancer patients. | Leyla Kilic Cetin Ordu Ibrahim Yildiz Fatma Sen Serkan Keskin Rumeysa Ciftci Kezban Nur Pilanci | 2016 | World Journal of Gastrointestinal Oncology2016，8，5： | 9 |
| 4 | Percutaneous peritoneal drainage in isolated neonatal gastric perforation显示文摘A comment on the article by He et al, 'Idiopathic neonatal pneumoperitoneum with favorable outcome:A case report and review', published on World Journal of Gastroenterology that reported a case of idiopathic neonatal pneumoperitoneum, possibly due to gastric perforation, with a favorable outcome without surgical intervention. | Mustafa Aydin Ugur Deveci Erdal Taskin Unal Bakal Mehmet Kilic | 2015 | World Journal of Gastroenterology2015，21，45： | 8 |
| 5 | Serum arylesterase and paraoxonase activity in patients with chronic hepatitis显示文摘AIM: To investigate the relationship between serum paraoxonase (PON1), AST, ALT, GGT, and arylesterase (AE) activity alterations and the degree of liver damage in patients with chronic hepatitis.METHODS: We studied 34 chronic hepatitis patients and 32 control subjects, aged between 35 and 65 years,in the Department of Infection and Clinical Microbiology at the Firat University School of Medicine. Blood samples were collected from subjects between 8:00 and 10:00 a.m. following a 12-h fast. Baseline and salt-stimulated PON1 activities were measured by the hydrolysis of paraoxon. Phenyl acetate was used as the substrate and formed phenol was measured spectrophotometrically at 270 nm after the addition of a 10-fold diluted serum sample in AE activity measurements.RESULTS: The results of this investigation revealed that the levels of AE activity decreased from 132±52 to 94±36 (29%), baseline PON1 activity from 452±112 to 164±67 (64%), salt-stimulated PON1 activity from 746±394 to 294±220 (61%), HDL from 58.4±5.1 to 47.2±5.6(20%), triglyceride from 133±51.2 to 86±34.0 (35%),while a slight increase in the level of LDL (from 163±54.1 to 177.3±56.0; 9%) and significant increases in the levels of AST (from 29±9.3 to 98±44), ALP (from 57.2±13.1 to 91±38.1), ALT (from 27.9±3.32 to 89±19.1), GGT (from 24.3±2.10 to 94±48.2), total bilirubin (from 0.74±0.02 to 1.36±0.06; 84%) and direct bilirubin (from 0.18±0.01 to 0.42±0.04; 133%) were detected.However, the levels of albumin, total protein, cholesterol,and uric acid were almost the same in chronic hepatitis and the control subjects.CONCLUSION: Low PON1 and AE activity may contribute to the increased liver dysfunction in chronic hepatitis patients by reducing the ability of HDL to retard LDL oxidation and might be clinically useful for monitoring the disease of chronic hepatitis. | Suleyman Sirri Kilic Suleyman Aydin Nermin Kilic Fazilet Erman Suna Aydin Ilhami Celik | 2005 | World Journal of Gastroenterology2005，11，46： | 4 |
| 6 | The Effects of Kinesio Tape Application on Functional Performance Measurements in Young Female Basketball Players with Chronic Ankle Instability显示文摘 | Berivan Beril Kilic Safinaz Yildiz Turker Sahinkaya Omer Batin Gozubuyuk Sensu Dincer | 2017 | Journal of Sports Science2017，5，4： | 4 |
| 7 | Sertraline-induced reproductive toxicity in male rats: evaluation of possible underlying mechanisms显示文摘 | Ozlem Atli Merve Baysal Gozde Aydogan-Kilic Volkan Kilic Seyda Ucarcan Burak Karaduman Sinem Ilgin | 2017 | Asian Journal of Andrology2017，19，6： | 4 |
| 8 | A new approach to the surgical treatment of parasitic cysts of the liver:Hepatectomy using the liver hanging maneuver显示文摘AIM: To review 11 patients with parasitic cysts of the liver, who were treated by hepatic lobectomy using the liver hanging maneuver (LHM). METHODS: Between January 2003 and June 2006, we retrospectively analyzed patients who underwent surgical treatment due to parasitic cysts of the liver, at the Ege University School of Medicine, Department of General Surgery. Of these, the patients who underwent hepatic lobectomy using the LHM were reviewed and evaluated for surgical treatment outcome. RESULTS: Over a three-year period, there were 102 patients who underwent surgical treatment for parasitic cysts of the liver. Of these, 11 (10%) patients with parasitic cysts of the liver underwent hepatic lobectomy using the LHM. Presenting symptoms were abdominal pain, dyspepsia, and cholangitis. Cyst locations were as follows: right lobe filled with cyst, 7 (63%); segmental location, 2 (18%); and multiple locations, 2 patients (18%). All patients underwent hepatic lobectomy with an anterior approach using the LHM. The intraoperative blood transfusion requirement was one unit for 3 patients and two units for one patient. Postoperative complications included pulmonary atelectasy (2, 18%) and pleural effusion (2, 18%). No significant morbidity or mortality was observed. CONCLUSION: We concluded that hepatic lobectomy using the LHM should be considered, not only for hepatic tumors or donor hepatectomy, but also to treat parasitic cysts of the liver. | Aydin Unal Yazici Pinar Zeytunlu Murat Kilic Murat Coker Ahmet | 2007 | World Journal of Gastroenterology2007，13，28： | 4 |
| 9 | Does N ratio affect survival in D1 and D2 lymph node dissection for gastric cancer?显示文摘AIM:To identify whether there could have been changes in survival if lymph node ratio (N ratio) had been used.METHODS:We assessed 334 gastric adenocarcinoma cases retrospectively between 2001 and 2009.Two hundred and sixteen patients out of 334 were included in the study.Patients were grouped according to disection1 (D1) or dissection 2 (D2) dissection.We compared the estimated survival and actual survival determined by Pathologic nodes (pN) class and N ratio,and SPSS 15.0 software was used for statistical analysis.RESULTS:Ninety-six (44.4%) patients underwent D1 dissection and 120 (55.6%) had D2 dissection.When groups were evaluated,23 (24.0%) patients in D1 and 21 (17.5%) in D2 had stage migration (P=0.001).When both D1 and D2 groups were evaluated for number of pathological lymph nodes,despite the fact that there was no difference in N ratio between D1 and D2 groups,a statistically significant difference was found between them with regard to pN1 and pN2 groups (P=0.047,P=0.044 respectively).In D1,pN0 had the longest survival while pN3 had the shortest.In D2,pN0 had the longest survival whereas pN3 had the shortest survival.CONCLUSION:N ratio is an accurate staging system for defining prognosis and treatment plan,thus decreasing methodological errors in gastric cancer staging. | Ibrahim Sakcak Baris Dogu Yildiz Fatih Mehmet Avsar Saadet Akturan Kemal Kilic Erdal Cosgun Enver O Hamamci | 2011 | World Journal of Gastroenterology2011，17，35： | 3 |
| 10 | Transcatheter aortic valve implantation: a revolution in the therapy of elderly and high-risk patients with severe aortic stenosis显示文摘Transcatheter 大动脉的阀门培植(TAVI ) 与严重征兆的大动脉的阀门狭窄为老或高风险的外科的病人的治疗在 interventional 心病学的地里代表一条真实革命。今天, TAVI 似乎与严重大动脉的狭窄在中间、也许低风险的病人的治疗玩一把钥匙和一个可靠角色。TAVI 也由新一代设备的发展从一个复杂、危险的过程演变为有效、安全的治疗。这篇文章试图与旧、新的一代 TAVI 设备考察 TAVI,临床的审判和注册表的背景和未来并且集中于与 procedural 以后结果有关的一些开的问题。 | Teoman Kilic Irem Yilmaz | 2017 | Journal of Geriatric Cardiology2017，14，3： | 3 |
| 11 | Comparison of total/active ghrelin levels in primary open angle glaucoma,pseudoexfoliation glaucoma and pseudoexfoliation syndrome显示文摘AIM:To investigate the levels of ghrelin(Gh),acylated ghrelin(AGh) and AGh/Gh ratio in the humor aqueous(HA) of cases with pseudoexfoliation syndrome(PXS),pseudoexfoliation glaucoma(PXG),primary open angle glaucoma(POAG) and to compare these with control subjects.METHODS:A prospective examination was made of the total Gh,and AGh levels in HA of 67 patients undergoing cataract surgery.Patients were divided into 4 groups.HA samples were aspirated at the beginning of the surgery,stored at -70℃.Gh and AGh quantification was performed with ELISA kits and the AGh/total-Gh ratios were calculated.ANOVA,Kruskal-Wallis,Chi-square and post-hoc tests were used for statistical analysis.RESULTS:Total Gh levels in HA were 189.2±45.6 pg/mL in the control group,199.2±32.9 pg/mL in PXS,180.6±20.9 pg/mL in PXG and 176.8±21.4 pg/mL in POAG groups(P>0.05).AGh levels in HA were 23.09±5.01 pg/mL in the control group,24.13±5.22 pg/mL in PXS,22.29±1.55 pg/m L in PXG and 19.69±2.93 pg/mL in POAG groups(P>0.05).The ratio of AGh/Gh was 10.3%±2.34% in the control group,13.03%±2.58% in PXS,12.3%±1.54% in PXG and 11.79%±1.41% in POAG groups(P=0.044).The difference between the PXS and control groups was significant(P=0.03).CONCLUSION:In spite of statistically insignificant results,the HA total Gh levels were lower than those of the control subjects but not parallel with the AGh levels in glaucoma patients.The relative increase in the AGh/Gh ratio in glaucoma cases supports the view that proportional increases of AGh might play a role in the pathogenesis of glaucoma. | Numan Eraslan Ufuk Elgin Emine Sen Aytul Kilic Pelin Yilmazbas | 2018 | International Journal of Ophthalmology(English edition)2018，11，5： | 3 |
| 12 | One-year experience in the retinopathy of prematurity: frequency and risk factors, short-term results and follow-up显示文摘· AIM: As a result of the increase in premature births and the advances in neonatal intensive care, retinopathy of prematurity (ROP) remains one of the most important causes of childhood blindness worldwide. The main factors in the development of ROP are gestational age, birth weight and oxygen therapy. ROP continues to gain importance due to the increasing survival rates of more immature babies. · METHODS: Between January 2007 and October 2008, 203 premature infants treated at the Neonatal Intensive Care Unit (NNICU) were prospectively enrolled and the relationship between known risk factors and the occurance of ROP was studied. · RESULTS: ROP in various stages developed in 86 cases (42.4%). Statistically significant correlations were found between the development of ROP and birth weight (P < 0.0001) gestational age (P <0.0001), oxygen treatment and its duration (P <0.0001 and P =0.002), mechanical ventilation (MV) and its duration (P =0,0001 and P =0.0001), apnea(P = 0.001), intraventricular hemorrhage (IVH) (P =0.046), sepsis (P =0.0001), use of erythropoietin (EPO) (P =0.003), the number of blood transfusions and frequency (P =0.0001 and P =0.0001), surfactant application (P =0.0001), the presence of patent ductus arteriosus (PDA) (P =0.001) or bronchopu- lmonary dysplasia (BPD) (P =0.0001). No significant correlations were found between the occurance of ROP and maternal pre-eclampsia (P =0.293), multiple pregnancy (P = 0.218), or hyperbilirubinemia (P =0.494). Severity of ROP was related significantly with birth weight (P =0.0001), but no significant correlation between severity of ROP and gestational age was present. · CONCLUSION: Early description and reduction of the risk factors related with the occurance of ROP with the help of routine screening programs may warrant the prevention of visual loss, however early ophthalmic diagnosis and treatment are still mandatory to provide better visual rehabilitation. · | Sariaydin Mehmet Atlihan Fusun Calkavur Sebnem Olukman Ozgur Ercan Gulten Ozturk Arif Taylan Kaya Kilic Fatma Gokaslan Filiz Altinyaprak Derya Malatyali Rana | 2011 | International Journal of Ophthalmology(English edition)2011，4，6： | 2 |
| 13 | Liver transplantation for HBV-related cirrhosis in Europe: An ELTR study on evolution and outcomes显示文摘 | Patrizia Burra Giacomo Germani Renè Adam Vincent Karam Alfredo Marzano Pietro Lampertico Mauro Salizzoni Franco Filipponi Jurgen L. Klempnauer Denis Castaing Murat Kilic Luciano De Carlis Peter Neuhaus Sezai Yilmaz Andreas Paul Antonio D. Pinna Andrew K. | 2012 | Journal of Hepatology2012，，： | 2 |
| 14 | Retrograde Intrarenal Surgery for the Treatment of Renal Stones in Patients With a Solitary Kidney显示文摘 | Gokhan Atis Cenk Gurbuz Ozgur Arikan Mert Kilic Sabri Pelit Cengiz Canakci Samet Gungor Turhan Caskurlu | 2013 | Urology2013，，： | 2 |
| 15 | Effect of 0.05% topical cyclosporine for the treatment of symptomatic subepithelial infiltrates due to adenoviral keratoconjunctivitis显示文摘Dear Sir,Iam Yonca A.Akova,MD-from the Department of Ophthalmology,Bayindir Kavaklidere Hospital,Turkey.I wrote this letter to evaluate the efficacy of 0.05%topical cyclosporine A(CsA)eye drops(Restasis Allergan,Irvine,USA)in symptomatic patients with recurrent subepithelial infiltrates(SEIs)due to adenoviral keratoconjunctivitis following steroid eye drops tapering or discontinuation. | Ilkay Kilic Muftuoglu Yonca A.Akova Sirel G.Gungor | 2016 | International Journal of Ophthalmology(English edition)2016，9，4： | 2 |
| 16 | Can biliary-cyst communication be predicted before surgery for hepatic hydatid disease: does size matter?显示文摘 | Mehmet Kilic Omer Yoldas Mahmut Koc Mehmet Keskek Nazile Karakose Tamer Ertan Erdal Gocmen Mesut Tez | 2008 | The American Journal of Surgery2008，，5： | 2 |
| 17 | 高血压患者正常血压后代的颈动脉内膜中层厚度和主动脉弹性显示文摘在不同年龄、种族和性别的患者中,高血压病史与高血压密切相关。该研究对患高血压父母的后代在发生高血压之前的颈动脉内膜中层厚度(carotid intimamedia thickness,CIMT)和主动脉弹性进行评估,以助于研究者确定其是否存在亚临床动脉粥样硬化。方法:纳入67名父母患原发性高血压的正常血压儿童(研究组)和39名父母无高血压的正常血压儿童(对照组). | 刘莉 叶鹏 Yildirim A Kosger P Ozdemir G Sahin FM Ucar B Kilic Z | 2015 | 中华高血压杂志2015，23，6： | 2 |
| 18 | Investigation of carbon contamination in lost foam castings of low carbon steel显示文摘Lost foam casting(LFC) process is a special casting method in which polymeric foam patterns with refractory coatings are utilized as a mould component. In this work, four types of foam: expandable polyethylene(EPE), expandable polypropylene(EPP) and expandable polystyrene(EPS) foams with two different densities were employed as pattern materials. LFC and conventional green sand mould casting methods were used to cast a low carbon steel, A216 Grade WCB. Both casting processes were carried out at 1,580 °C. Chemical analysis results showed that the carbon contamination level was high and was influenced by pattern type. Metallographic investigations revealed a significant increase in the percentage of pearlite phase in all LFC samples. Densities of manufactured samples were calculated in order to evaluate porosity of the products. It was determined that the densities of the LFC samples were lower than the green sand mould cast reference sample(RS). Vickers hardness tests were also carried out and increments in hardness values with increased carbon content was observed. | Oznur Kilic Serhat Acar Alptekin Kisasoz Kerem Altug Guler | 2018 | China Foundry2018，15，5： | 2 |
| 19 | Comparison of Two Different Treatment Protocols in Helicobacter pylori Eradication显示文摘 | Isilay Nadir Ozlem Yonem Yasemin Ozin Zeki Mesut Yalin Kilic Orhan Sezgin | 2011 | Southern Medical Journal2011，，2： | 2 |
| 20 | Bone mass in axial spondyloarthritis:A literature review显示文摘AIM: To review the published literature reporting bone loss in patients with axial spondyloarthritis(SpA) particularly those studies using dual X-ray absorptiometry(DXA) methods. METHODS: This literature review examines the reported bone mass in patients with ax-SpA, particularly those using the DXA methods. The MEDLINE, Web of Science and Scopus databases were searched for relevant articles published between September 1992 and November 2013. Some of used search terms were ankylosing spondylitis(AS), SpA, spondyloarthropathy, bone loss, bone mass, osteopenia, bone mineraldensity, osteoporosis(OP), densitometry. Studies in which bone loss was investigated by using DXA in patients with Sp A were eligible. Each article was reviewed and the key elements were noted.RESULTS: There were 286 hits on MEDLINE, 200 on Web of Science and 476 on Scopus. After applying inclusion and exclusion criteria, we identified 55 articles in our systematic search. The sample size of the studies varied from 14 to 332 patients with SpA. The reported age range varied from 25 to 56 years in the reviewed studies. The symptom duration of patients with axS pA varied from 1.6 to 49 years. There were more males than females in these studies. Most of the recruited females were premenopausal women. Reported HLA-B27 positivity changed between 19% to 95%. The prevalence of OP and osteopenia in patients with Sp A varied from 3%-47% to 5%-88%, respectively, in the included studies. In particular, the prevalence of OP and osteopenia ranged from 2.0%-47.0% and 5.0%-78.3%, respectively, in patients with AS. There are conflicting results regarding the relationship among disease activity, acute phase response and bone mass. Some studies suggest good correlation of bone mass with disease activity and acute phase reactants.CONCLUSION: Bone loss may be determined in patients with ax Sp A at the lumbar spine or proximal femur even in the early phase of the disease and may be associated with inflammation(bone marrow edema) at the vertebral colon. | Erkan Kilic Salih Ozgocmen | 2015 | World Journal of Orthopedics2015，6，2： | 2 |
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