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| 1 | Rubber band ligation for 750 cases of symptomatic hemorrhoids out of 2200 cases显示文摘AIM: To study the results for the treatment of symptomatic hemorrhoids using rubber band ligation (RBL) method. METHODS: A retrospective study for 750 patients who came to the colorectal unit from June, 1998 to September, 2006, data was retrieved from archived fi les. RBL was performed using the Mc Gown applicator on an outpatient basis. The patients were asked to return to out-patient clinic for follow up at 2 wk, 1 mo, 6 mo and through telephone call every 6 mo for 2 years). RESULTS: After RBL, 696 patients (92.8%) were cured with no difference in outcome for second or third degree hemorrhoids (P = 0.31). Symptomatic recurrence was detected in 11.04% after 2 years. A total of 52 patients (6.93%) had 77 complications from RBL which required no hospitalization. Complications were pain, rectal bleeding and vaso-vagal symptoms(4.13%, 4.13% and 1.33% of patients, respectively). At 1 mo there were a significant improvement in mean SF-36 scores over baseline in five items, while after 2 years there were improvement in all items over baseline, but not significant. No significant manometeric changes after band ligation. CONCLUSION: RBL is a simple, safe and effective method for treating symptomatic second and third degree hemorrhoids as an out patient procedure with signifi cant improvement in quality of life. RBL doesn't alter ano-rectal functions. | Ayman M El Nakeeb Amir A Fikry Waleed H Omar Elyamani M Fouda Tito A El Metwally Hosam E Ghazy Sabry A Badr Mohmed Y Abu Elkhar Salih M Elawady Hisham H Abd Elmoniam Waiel W Khafagy Mosaad M Morshed Ramadan E El Lithy Mohamed E Farid | 2008 | World Journal of Gastroenterology2008，14，42： | 24 |
| 2 | Prognostic efficacy of inflammation-based markers in patients with curative colorectal cancer resection显示文摘AIM To evaluate the prognostic significance of neutrophilto-lymphocyte ratio(NLR), platelet-to-lymphocyte ratio(PLR), lymphocyte-to-monocyte ratio(LMR), and prognostic nutritional index(PNI) and other clinicopathological factors in patients undergoing curative resection of colon cancer.METHODS183 patients with histologically proven colorectal cancer who had undergone potentially curative resection between 2010 and 2016 at Ankara Numune Training and Research Hospital were retrospectively analyzed and clinicopathological characteristics included age, sex, tumor type, grade, size and localization, the number of metastatic and total number of lymph nodes removed, vascular and perineural invasion of the tumor, TNM stages, tumor marker levels(CEA, CA19-9, AFP, CA-125, CA15-3), complete blood counts, albumin levels, overall survival(months), NLR, PLR, LMR and PNI ratios were retrospectively reviewed and analyzed from the electronic database. The primary outcome measure was overall survival.RESULTS Regarding overall survival, on univariate analysis the following variables were significantly associated with poor outcome following resection: T-stage(P = 0.037), lymph node invasion(P = 0.037), cancer stage(P = 0.034), CEA(P = 0.042), CA19-9(P = 0.004), and PNI(P = 0.001). To evaluate the independent prognostic value, multivariate Cox proportional hazard analysis to control for other prognostic factors was used. Using cancer-specific death as an end point for NLR, PLR, LMR, PNI and CA19-9 the optimal cut off values were calculated by ROC analysis. Regarding overall survival, on multivariate analysis high CA19-9(HR = 1.001, 95%CI: 1.00-1.002, P = 0.012) and low PNI(HR = 0.938, 95%CI: 0.891-0.987, P = 0.014) were the only variables independently associated with shortened overall survival. Patients with a PNI < 35 had a median OS of 52.25 mo. In contrast, patients with an PNI > 35 had a median OS of 66 mo. Patients with a CA 19-9 < 17 had a median OS of 66 mo and in patients with a CA19-9 > 17 had a median OS of 53.76 mo.CONCLUSION This study shows that decrease in the PNI and increase in CA 19-9 is associated with poor survival in patients with resectable colon cancer. | özgür Akgül Erdinc Cetinkaya Metin Yalaza Sabri özden Mesut Tez | 2017 | World Journal of Gastrointestinal Oncology2017，9，7： | 11 |
| 3 | Biological subtypes of breast cancer: Prognostic and therapeutic implications显示文摘Breast cancer is a heterogeneous complex of diseases, a spectrum of many subtypes with distinct biological features that lead to differences in response patterns to various treatment modalities and clinical outcomes. Traditional classification systems regarding biological characteristics may have limitations for patient-tailored treatment strategies. Tumors with similar clinical and pathological presentations may have different behaviors. Analyses of breast cancer with new molecular techniques now hold promise for the development of more accurate tests for the prediction of recurrence. Gene signatures have been developed as predictors of response to therapy and protein gene products that have direct roles in driving the biology and clinical behavior of cancer cells are potential targets for the development of novel therapeutics. The present review summarizes current knowledge in breast cancer molecular biology, focusing on novel prognostic and predictive factors. | Ozlem Yersa L Sabri Barutca | 2014 | World Journal of Clinical Oncology2014，5，3： | 10 |
| 4 | Mismatch repair genes (hMLH1, hPMS1, hPMS2, GTBP/hMSH6,HMSH2) in the pathogenesis of hepatocellular carcinoma显示文摘AIM: DNA misrnatch repair (MMR) is an impotent mechanism for maintaining fidelity of genomic DNA. Abnormalities in one or more MMR genes are implicated in the development of many cancers. We investigated the role of expression of MMR genes (hMLH1, hPMS1, hPMS2, GTBP/hMSH6, hMSH2) in hepatocellular carcinogenesis. METHODS: We evaluated the expression level of MMR genes in 33 hepatocellular carcinoma (HCC) cases using the multiplex reverse transcription (RT) PCR assays, as well as in 16 cases of normal adjacent hepatic tissues. Β-actin gene was used as an internal control and calibrator for quantification of gene expression. RESULTS: Out of the 33 studied cases, 25 were HCV positiveand 30 (90.9%) showed reduced expression in one or more of the studied MMR genes. Reduced expression was found in hMSH2 (71.9%), hMLH1 (53.3%), GTBP (51.1%), hPMS2 (33.3%) and hPMS1 (6%). A significant correlation was found between reduced expression of hPMS2(P= 0.0069) and GTBP(P= 0.0034), hPMS2and non-cirrhosis (P= 0.0197),hMLH1 and high grade. On the other hand, 57.1%, 50%, 20%, 18.8%, and 6% of the normal tissues distant to tumors showed reduced expression of hMSH2, hMLH1, GTBP, hPMS2, and hPMS1 respectively. Multivariate analysis revealed a significant correlation between the expression level of hMSH2(P= 0.008), hMLH1 (P= 0.001) and GTBP (P = 0.032)and HCC, between hPMS2, GTBP and HCVassociated HCC (P<0.001, 0.002).CONCLUSION: Reduced expression of MMR genes seemsto play an important role in HCV-associated HCC. hPMS2 islikely involved at an early stage of hepatocarcinogenesis since it was detected in normal adjacent tissues. Reduced expression of hPMS2 provides a growth advantage and stimulates proliferation which encourages malignant transformation in non-cirrhotic HCV-infected patients via acquisition of more genetic damages. | Abdel-Rahman N. Zekri Gelane M. Sabry Abeer A. Bahnassy Kamal A. Shalaby Sabrin A.Abdel-Wahabh Serag Zakaria | 2005 | World Journal of Gastroenterology2005，11，20： | 10 |
| 5 | Influence of fly ash and sewage sludge application on wheat biomass production,nutrients availability,and soil properties显示文摘The influence of fly ash(FA)applied alone and/or with sewage sludge(SS)on wheat(Triticum vulgare)grain yield,biomass production and soil properties was studied in a field experiment.The results showed that both FA and SS significantly increased grain yield and plant biomass.FA applied alone increased significantly soil pH and EC while FA applied together with SS did not significantly affect them compared to mono FA treatment.Soil pH and EC values increased with time in FA and FA-SS treatments.SS increased soil organic matter and total N content and SS applied together with FA increased also available soil B.From the plant nutrients tested only tissue N concentration was increased significantly in all treatments compared to control.Copper,Zn,Mn,Ni,and Pb at both available and total concentrations are significantly affected. | Christos Tsadilas Vasilios Samaras E.Evangelou Sabry M.Shaheen | 2014 | International Journal of Coal Science & Technology2014，1，2： | 8 |
| 6 | Early detection of response to imatinib therapy for gastrointestinal stromal tumor by using 18F-FDG-positron emission tomography and computed tomography imaging显示文摘有变形胃肠的基质肿瘤的 41 年的老女性被指 18F-FDG-positron 排放断层摄影术和计算断层摄影术(PET/CT ) 与 imatinib 在一个月前后扫描治疗(Glivec 收款机, Gleevec 收款机, Novartis,巴塞尔,瑞士) ,一个酷氨酸激酶禁止者(400 mg/d ) 。新陈代谢的反应在一月治疗前后被评估。最大的 standardised 举起价值(SUV ) 的减少是 79%( 从 9.8 ~ 2.1 ) 。正电子排放断层摄影术在 imatinib 治疗的一个月以后表明了完全的新陈代谢的反应。另外,以前的损害与花冠相比是计算机化的 tomographic 图象。根据 CT 图象在在治疗前后的肿瘤的尺寸没有差别。然而,新陈代谢的活动被禁止。18F-FDG-PET 是为对在有胃肠的基质肿瘤的病人的一个月 imatinib 治疗的反应的察觉的一个珍贵方法。 | Sabri Zincirkeser Alper Sevinc M Emin Kalender Celalettin Camci | 2007 | World Journal of Gastroenterology2007，13，15： | 7 |
| 7 | Molecular detection of monocyte chemotactic protein-1 polymorphism in spontaneous bacterial peritonitis patients显示文摘AIM: To investigate the association of the functional monocyte chemotactic protein-1(MCP-1) promoter polymorphism(A-2518G) with spontaneous bacterial peritonitis(SBP).METHODS: Fifty patients with post-hepatitis C liver cirrhosis and ascites were categorized into two groups; group Ⅰ included 25 patients with SBP and group Ⅱ included 25 patients free from SBP. In addition, a group of 20 healthy volunteers were included. We assessed the MCP-1 gene polymorphism and gene expression as well as interleukin(IL)-10 levels in both blood and ascitic fluid. RESULTS: A significant MCP-1 gene polymorphism was detected in groups Ⅰ and Ⅱ(P = 0.001 and 0.02 respectively). Group Ⅰ was associated with a significantly higher frequency of AG genotype [control 8(40%) vs SBP 19(76.0%), P < 0.001], and group Ⅱ was associated with a significantly higher frequency of GG genotype when compared to healthy volunteers [control 1(5%) vs cirrhotic 16(64%), P < 0.001]. Accordingly, the frequency of G allele was significantly higher in both groups(Ⅰ and Ⅱ) [control 10(25%) vs SBP 27(54%), P < 0.001 and vs cirrhotic 37(74.0%), P < 0.001, respectively]. The total blood and ascetic fluid levels of IL-10 and MCP-1 gene expression were significantly higher in group Ⅰ than in group Ⅱ. Group Ⅰ showed significant reductions in the levels of MCP-1 gene expression and IL-10 in the whole blood and ascetic fluid after therapy. CONCLUSION: MCP-1 GG genotype and G allele may predispose HCV infected patients to a more progressive disease course, while AG genotype may increase the susceptibility to SBP. Patients carrying these genotypes should be under supervision to prevent or restrict further complications. | Maysa Kamal Salama Dina Sabry Mohamed AS Al-Ghussein Rasha Ahmed Sayed AbdAllah Fatma Mohamed Taha Wael Fathy Miriam Safwat Wadie Mona Nabih Amr Abul-Fotouh Tarneem Darwish | 2014 | World Journal of Gastroenterology2014，20，33： | 7 |
| 8 | Temperature-gradient induced microstructure evolution in heat-affected zone of electron beam welded Ti-6Al-4V titanium alloy显示文摘The heat-affected zone(HAZ) of electron beam welded(EBW) joint normally undergoes a unique heat-treating process consisting of rapid temperature rising and dropping stages, resulting in temperature-gradient in HAZ as a function of the distance to fusion zone(FZ). In the current work,microstructure, elements distribution and crystallographic orientation of three parts(near base material(BM) zone, mid-HAZ and near-FZ) in the HAZ of Ti-6Al-4V alloy were systematically investigated. The microstructure observation revealed that the microstructural variation from near-BM to near-FZ included the reduction of primary α(αp) grains, the increase of transformed β structure(βt) and the formation of various α structures. The rim-α, dendritic α and abnormal secondary α(αs) colonies formed in the mid-HAZ, while the 'ghost' structures grew in the near-FZ respectively. The electron probe microanalyzer(EPMA) and electron back-scattered diffraction(EBSD) technologies were employed to evaluate the elements diffusion and texture evolution during the unique thermal process of welding. The formation of the various α structures in the HAZ were discussed based on the EPMA and EBSD results. Finally, the nanoindentation hardness of 'ghost' structures was presented and compared with nearby βt regions. | Shilin Zhang Yingjie Ma Sensen Huang Sabry S.Youssef Min Qi Hao Wang Jianke Qiu Jiafeng Lei Rui Yang | 2019 | Journal of Materials Science & Technology2019，35，8： | 6 |
| 9 | New parameter in diagnosis of acute appendicitis:Platelet distribution width显示文摘AIM:To investigate the diagnostic accuracy of the mean platelet volume and platelet distribution width in acute appendicitis.METHODS:This retrospective,case-controlled study compared 295 patients with acute appendicitis(Group?Ⅰ),100 patients with other intra-abdominal infections(GroupⅡ),and 100 healthy individuals(GroupⅢ)between January 2012 and January 2013.The age,gender,and white blood cell count,neutrophil percentage,mean platelet volume,and platelet distribution width values from blood samples were compared among the groups.Statistical analyses were performed using SPSS for Windows 21.0 software.In addition,the sensitivity,specificity,positive and negative predictive values and likelihood ratios,and diagnostic accuracy were calculated.RESULTS:The mean ages of patients were 29.9±12.0years for Group?Ⅰ,31.5±14.0 years for GroupⅡ,and30.4±13.0 years for GroupⅢ.Demographic features such as age and gender were not significantly different among the groups.White blood cell count,neutrophil percentage and platelet distribution width were significantly higher in Group?Ⅰ?compared to groupsⅡandⅢ(P<0.05).Diagnostically,the sensitivity,specificity and diagnostic accuracy were 73.1%,94.0%,and 78%for white blood cell count,70.0%,96.0%,and 76.0%for neutrophil percentage,29.5%,49.0%,and 34.0%for mean platelet volume,and 97.1%,93.0%,and 96.0%for platelet distribution width,respectively.The highest diagnostic accuracy detected was for platelet distribution width between Group?Ⅰ?and GroupⅢ(P<0.01).CONCLUSION:Platelet distribution width analysis can be used for diagnosis of acute appendicitis without requiring additional tests,thus reducing the cost and loss of time. | Bulent Dinc Alten Oskay Selcan Enver Dinc Bilge Bas Sabri Tekin | 2015 | World Journal of Gastroenterology2015，21，6： | 5 |
| 10 | Analysis of the high-temperature dry sliding behavior of CoCrFeNiTi0.5Alx high-entropy alloys显示文摘In this study,CoCrFeNiTi0.5Alx high‐entropy alloys were produced by induction melting and their dry sliding wear behavior was examined at different temperatures.In addition to face‐centered cubic(FCC)phases,low amounts of a tetragonal phase were detected in the microstructures of alloys without Al and microscratches were formed by wear particles on the worn surfaces of the alloy specimens.Two body‐centered cubic(BCC)phases were detected in the alloy with 0.5Al and a fatigue‐related extrusion wear mechanism was detected on the worn surface.The alloy specimen with a high Al content exhibited the best wear characteristics.No wear tracks were formed in single‐phase BCC intermetallic alloys at room temperature and they exhibited a higher wear strength at high temperatures when compared to other samples. | Azmi ERDOGAN Mustafa Sabri GOK Sakin ZEYTIN | 2020 | Friction2020，8，1： | 5 |
| 11 | Dynamics and Predictive Control of Gas Phase Propylene Polymerization in Fluidized Bed Reactors显示文摘A two-phase dynamic model,describing gas phase propylene polymerization in a fluidized bed reactor,was used to explore the dynamic behavior and process control of the polypropylene production rate and reactor temperature.The open loop analysis revealed the nonlinear behavior of the polypropylene fluidized bed reactor,justifying the use of an advanced control algorithm for efficient control of the process variables.In this case,a centralized model predictive control(MPC) technique was implemented to control the polypropylene production rate and reactor temperature by manipulating the catalyst feed rate and cooling water flow rate respectively.The corresponding MPC controller was able to track changes in the setpoint smoothly for the reactor temperature and production rate while the setpoint tracking of the conventional proportional-integral(PI) controller was oscillatory with overshoots and obvious interaction between the reactor temperature and production rate loops.The MPC was able to produce controller moves which not only were well within the specified input constraints for both control variables,but also non-aggressive and sufficiently smooth for practical implementations.Furthermore,the closed loop dynamic simulations indicated that the speed of rejecting the process disturbances for the MPC controller were also acceptable for both controlled variables. | Ahmad Shamiri Mohamed azlan Hussain Farouq sabri Mjalli Navid Mostoufi Seyedahmad Hajimolana~ | 2013 | Chinese Journal of Chemical Engineering2013，21，9： | 4 |
| 12 | Assessment of heme oxygenase-1 (HO-1) activity in the cavernous tissues of sildenafil citrate-treated rats显示文摘瞄准:估计他我在勃起组织 ofsildenafil 的 oxygenase-1 (HO-1 ) 活动对待柠檬酸盐的老鼠。方法:192 只 Sprague-Dawley 雄的老鼠,划分了成四个相等的组,被调查。组织 1,控制组,收到的常规动物食物;由胃内试管组织 2 收到的 sildenafil 柠檬酸盐;组 3 收到的 sildenafiland 惊讶禁止者(锌原卟啉, ZnPP ) ;并且组 4 收到了 sildenafil 和氮的 oxidesynthase (NOS ) 禁止者 L-nitroarginine 甲基酉旨(L 名字) 。从每个组的 12 只老鼠在 0.5 h, 1 h, 2 h 和药管理的 3 h 以后被打死。然后,在勃起组织的 HO-1 活动, cGMP 层次和 NOSenzymatic 活动被估计。结果:在勃起组织, HO-1activity, NOS 酶的活动和 cGMP,集中在整个实验与另外的组相比增加了显著地对待 insildenafil 的老鼠。收到任何一个 HOor NOS 禁止者的老鼠在这些参数显示出重要减少。酶的活动表明了的 HO-1 勃起组织活动和 NOS 与 cGMP 层次的积极重要关联(r =0.646, r = 0.612 分别地;P <
0.001 ) 。结论:在勃起组织的 PDE_5 禁止者 sildenafilcitrate 的行动部分通过在 HO-1 和 NOS 活动之间的相互依赖的关系被调停。 | M. Talaat Abdel Aziz M. Farid Al-Asmar Taymour Mostafa Hazem Atta Laila Rashed Dina Sabry Shedeed Ashour Ahmed T. Abdel Aziz | 2007 | Asian Journal of Andrology2007，9，3： | 4 |
| 13 | Short-term effects of intravitreal triamcinolone acetonide injection on ocular blood flow evaluated with color Doppler ultrasonography显示文摘AIM:To evaluate the changes in ocular blood flow with color Doppler ultrasonography(CDU) after intravitreal triamcinolone acetonide(IVTA) injection.METHODS:A total of 46 patients who underwent IVTA(4 mg/0.1 mL) injection for diabetic macular edema(DME)(n =22), central retinal vein occlusion(CRVO)(n =12) and choroidal neovascular membrane(CNVM)(n =12) were included in the study. Peak systolic velocity(PSV), end diastolic velocity(EDV) and resistivity index(RI) were measured from the ophthalmic artery(OA), the central retinal artery(CRA) and the posterior ciliary artery(PCA)of each patient with CDU before, at the end of the first week and at the end of the first month following IVTA injection.RESULTS:In the DME group, PSV of OA at the first of the first month(mean ±SD)(37.48 ±10.87 cm/s) increased compared to pre-injection value(31.39 ±10.84 cm/s)(P =0.048). There was a statistically significant decrease(P =0.049) in PSV of CRA at the end of the first month(7.97±2.67 cm/s) compared to the pre-injection(9.47±3.37 cm/s).There was not any statistically significant difference onthe other parameters in the DME group. Also, there was not any statistically significant difference on the ocular blood flow values in the CRVO and CNVM groups.CONCLUSION:We observed that 4 mg/0.1 mL IVTA increased PSV of OA and decreased PSV of CRA in DME patients and did not have any effect on ocular blood flow values of CRVO and CNVM patients. | Mustafa Alpaslan Anayol Yasin Toklu Elif Asik Kamberoglu Sabri Raza Hasan Basri Arifoglu Huseyin Simavli Ayse Gul Kocak Altintas Saban Simsek | 2014 | International Journal of Ophthalmology(English edition)2014，7，5： | 4 |
| 14 | A collaborative approach for urban underground space development toward sustainable development goals:Critical dimensions and future directions显示文摘The utilization of urban underground space(UUS)offers an effective solution to urban problems but may also negatively affect urban development.Therefore,UUS development needs better concerted guidelines to coordinate various urban systems and the multiple components of the underground world.Sustainable Development Goals(SDGs),which should be viewed as important yardsticks for UUS development,do not explicitly mention urban underground space,although many of them are affected by both the positive and negative consequences of its development.To fill this gap,this review lays the foundations of relevant UUS concepts and uses exemplary cases to reveal that 11 out of 17 SDGs can be linked with UUS uses.These linkages also manifest that land administration,integrated planning,architectural design,and construction technology are critical dimensions for increasing the contributions of UUS to the realization of SDGs.To achieve multi-disciplinary synergies among these four critical dimensions,a collaborative approach framework based on spatial data infrastructure is required.Thus,this work provides academics and practitioners with a holistic view of sustainable UUS development. | Fang-Le PENG Yong-Kang QIAO Soheil SABRI Behnam ATAZADEH Abbas RAJABIFARD | 2021 | Frontiers of Structural and Civil Engineering2021，15，1： | 4 |
| 15 | Biological activities of sulfated polysaccharides from tropical seaweeds显示文摘 | L.S. Costa G.P. Fidelis S.L. Cordeiro R.M. Oliveira D.A. Sabry R.B.G. Camara L.T.D.B. Nobre M.S.S.P. Costa J. Almeida-Lima E.H.C. Farias E.L. Leite H.A.O. Rocha | 2009 | Biomedicine & Pharmacotherapy2009，，1： | 3 |
| 16 | Fatigue crack tip plastic zone ofα+βtitanium alloy with Widmanstatten microstructure显示文摘The recent studies had focused on the fatigue crack propagation behaviors of α+β titanium alloys with Widmanstatten microstructure. The fascinated interest of this type of microstructure is due to the superior fatigue crack propagation resistance and fracture toughness as compared to other microstructures,which was believed to be related to the fatigue crack tip plastic zone(CTPZ). In this study, the plastic deformation in fatigue CTPZ of Ti-6 A1-4 V titanium alloy with Widmanstatten microstructure was characterized by scanning electron microscope(SEM) and electron backscatter diffraction(EBSD). The results showed that large-scale slipping and deformation twinning were generated in fatigue CTPZ due to the crystallographic feature of the Widmanstatten microstructure. The activation of twinning was related to the rank of Schmid factor(SF) and the diversity of twin variants developing behaviors reflected the influence of SF rank. The sizes of CTPZ under different stress intensity factors(K) were examined by the white-light coherence method, and the results revealed that the range of the plastic zone is enlarged with the increasing K(or crack length), while the plastic strain decreased rapidly with the increasing distance from the crack surface. The large-scale slipping and deformation twinning in Widmannstatten microstructure remarkably expanded the range of fatigue CTPZ, which would lead to the obvious larger size of the observed CTPZ than that of the theoretically calculated size. | Yingjie Ma Sabry S.Youssef Xin Feng Hao Wang Sensen Huang Jianke Qiu Jiafeng Lei Rui Yang | 2018 | Journal of Materials Science & Technology2018，34，11： | 3 |
| 17 | Airborne Pollen Grains Of Afyon, Turkey显示文摘The airborne pollen grains of Afyon have been studied for a two_year period (1999-2000) with a Durham sampler. A total of 14 367 pollen grains belonging to 40 taxa have been identified and recorded with some unidentified ones. Of them, 6 732 were identified in 1999 and 7 635 in 2000. Of the total pollen grains, 69.67% were arboreal, 26.64% non_arboreal and 3.68 % unidentified. The majority of the investigated pollen grains were from Pinus, Gramineae, Cupressaceae, Platanus , Chenopodiaceae/Amaranthaceae, Quercus, Ailanthus, Moraceae, Juglans , Salix, Cedrus and Rosaceae. The highest level of pollen grains was in May. | Adem BICAKCI 1, Süheyla ERGUN 2, Sevcan TATLIDIL 1, Hulusi MALYER 1, Sabri ?ZYURT 2, Ahmet AKKAYA 3, Nihat SAPAN 5 Department of Biology, Faculty of Science, University of Uludag, Bursa, Turkey 2. Department of Biology, Faculty of Science, University of Afyon Kocatepe, Afyon Turkey 3. Department of Pulmonology, Faculty of Medicine, University of Süleyman Demirel, Isparta, Turkey 4. Division of Pediatric Allergy, Faculty of Medicine, University of Uludag, Bursa, Turkey) | 2002 | Acta Botanica Sinica2002，44，11： | 3 |
| 18 | Visual and refractive outcomes of posterior chamber phakic IOL in stable keratoconus显示文摘We evaluated the visual and refractive outcomes after phakic visian toric implantable collamer lens(ICL) insertion in stable keratoconus(KC). This retrospective study investigated toric ICL implantation in 14 eyes of 8 patients with stable KC. After 6 mo, the mean uncorrected distance visual acuity improved significantly from 0.77 to 0.15 logMAR. The mean best corrected distance visual acuity(BCDVA) improved from 0.18±0.1 to 0.15±0.1 logMAR. Fifty percent of eyes maintained their preoperative BCDVA; 42.8% gained one line. There was no statistical difference in high order or coma aberration. The mean refractive manifest spherical equivalent(MSE), mean refractive manifest spherical error, mean manifest astigmatism decreased significantly postoperatively. At 6 mo postoperatively, our achieved mean spherical equivalent was approximately 74%. No intraoperative or postoperative complications occurred. Toric ICL implantation was effective, predictable and safe to correct refractive error and improve visual acuity in patients with stable KC. | Sherif H Emerah Moataz M Sabry Hisham A Saad Waleed A Ghobashy | 2019 | International Journal of Ophthalmology(English edition)2019，12，5： | 2 |
| 19 | Short‐term evaluation of autologous transplantation of bone marrow–derived mesenchymal stem cells in patients with cirrhosis: Egyptian study显示文摘 | Mona A. Amin Dina Sabry Laila A. Rashed Wael M. Aref Mohamed Ahmed el‐Ghobary Marwa Salah Farhan Hany Ahmed Fouad Youssef Abdel‐Aziz Youssef | 2013 | Clin Transplant2013，，4： | 2 |
| 20 | Low-density lipoprotein receptor genetic polymorphism in chronic hepatitis C virus Egyptian patients affects treatment response显示文摘AIM: To correlate a genetic polymorphism of the low-density lipoprotein(LDL) receptor with antiviral responses in Egyptian chronic hepatitis C virus(HCV) patients.METHODS: Our study included 657 HCV-infected patients with genotype 4 who received interferonbased combination therapy. Patients were divided into two groups based on their response to therapy: 356 were responders, and 301 were non-responders. Patients were compared to 160 healthy controls. All patients and controls underwent a thorough physical examination, measurement of body mass index(BMI) and the following laboratory tests: serum alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, albumin, total bilirubin, direct bilirubin, prothrombin time, prothrombin concentration, INR, complete blood count, serum creatinine, fasting blood sugar, HCV antibody, and hepatitis B surface antigen. All HCV patients were further subjected to the following laboratory tests: HCV-RNA using quantitative polymerase chain reaction(PCR), antinuclear antibodies, thyroid-stimulating hormone, an LDL receptor(LDLR) genotype study of LDLR exon8 c.1171G>A and exon-10 c.1413G>A using real-time PCR-based assays, abdominal ultrasonography, ultrasonographic-guided liver biopsy, and histopathological examination of liver biopsies. Correlations of LDL receptor polymorphisms with HAI, METAVIR score, presence of steatosis, and BMI were performed in all cases.RESULTS: There were no statistically significant differences in response rates between the different types of interferon used or LDLR exon10 c.1413G>A. However, there was a significant difference in the frequency of the LDL receptor exon8 c.1171G>A genotype between cases(AA: 25.9%, GA: 22.2%, GG: 51.9%) and controls(AA: 3.8%, GA: 53.1% and GG: 43.1%)(P < 0.001). There was a statistically significant difference in the frequency of the LDLR exon 8C:1171 G>A polymorphism between responders(AA: 3.6%, GA: 15.2%, GG: 81.2%) and nonresponders(AA: 52.2%, GA: 30.6%, GG: 17.2%)(P < 0.001). The G allele of LDL receptor exon8 c.1171G>A predominated in cases and controls over the A allele, and a statistically significant association with response to interferon was observed. The frequency of the LDLR exon8 c.1171G>A allele in non-responders was: A: 67.4% and G: 32.6 vs A: 11.2% and G: 88.8% in responders(P < 0.001). Therefore, carriers of the A allele exhibited a 16.4 times greater risk for nonresponse. There was a significant association between LDL receptors exon8 c.1171G>A and HAI(P < 0.011). There was a significant association between LDL receptors exon8 c.1171G>A and BMI. The mean BMI level was highest in patients carrying the AA genotype(28.7 ± 4.7 kg/m2) followed by the GA genotype(28.1 ± 4.8 kg/m2). The lowest BMI was the GG genotype(26.6 ± 4.3 kg/m2)(P < 0.001). The only significant associations were found between LDL receptors exon8 c.1171G>A and METAVIR score or steatosis(P < 0.001).CONCLUSION: LDL receptor gene polymorphisms play a role in the treatment response of HCV and the modulation of disease progression in Egyptiansinfected with chronic HCV. | Mazen Naga Mona Amin Dina Algendy Ahmed Elbadry May Fawzi Ayman Foda Serag Esmat Dina Sabry Laila Rashed Samia Gabal Manal Kamal | 2015 | World Journal of Gastroenterology2015，21，39： | 2 |
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