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| 1 | ELISA快速测定小麦中硫丹及硫丹硫酸酯显示文摘研究应用酶联免疫方法,快速检测小麦中硫丹及硫丹硫酸酯。小麦经80%甲醇提取后,用PBS/T缓冲液稀释5倍后,酶联免疫方法直接测定。方法平均回收率为73.3%~88.8%,线性范围1.5μg/L^25μg/L,最低检测限0.4μg/L,变异系数<10.03%。经气相色谱/质谱联用方法验证,灵敏度、重现线和准确度均符合快速检测要求。该法具有快速、简便、低耗、易操作等特点。 | 吕潇 聂燕 陈子雷 黎秀卿 李慧冬 李瑞菊 张红 万春燕 朱端卫 Lee Nanju A Shields Ross Kennedy Ivan R | 2006 | 中国粮油学报2006，21，5： | 6 |
| 2 | P2Y12受体抑制剂联合质子泵抑制剂对急性冠脉综合征患者缺血事件影响的临床分析显示文摘目的本研究旨在分析P2Y12受体抑制剂联合质子泵抑制剂(PPI)治疗对经皮冠状动脉介入(PCI)术后的急性冠脉综合征患者缺血事件的影响。方法基于国际多中心回顾性注册登记研究,纳入2003至2014年因急性冠脉综合征人院行PCI术的患者,分为PPI组及非PPI组并随访1年,主要临床终点为全因死亡/再发心肌梗死的复合终点。根据P2Y12受体抑制剂种类,将入组患者分为氯吡格雷组及替格瑞洛组,并比较不同药物与PPI联用发生临床终点事件的风险。结果研究入选9429例患者,PPI组占54.8%,具有更多高危因素。Cox回归结果提示PPI组较非PPI组全因死亡/再发心肌梗死复合事件的发生差异无统计学意义(HR1.00,95%CI 0.86—1.18)。根据P2Y12抑制剂种类不同分为氯吡格雷组和替格瑞洛组,不同P2Y12受体抑制剂联用PPI较未联用PPI患者的临床终点无差异,联用PPI的氯吡格雷组与替格瑞洛组的临床终点差异也无统计学意义。结论急性冠脉综合征患者PPI与P2Y12受体抑制剂联用不增加全因死亡和再发心肌梗死风险,尤其PPI联用氯吡格雷在患者的缺血事件上与替格瑞洛比较差异无统计学意义。 | 冯斯婷 严妍 范婧尧 王晓 郑文 聂绍平 Sergio Raposeiras-Roubin Emad Abu-Assi Jose P Simao Henriques Fabrizio D' Ascenzo Jorge Saucedo Jose R Conzalez-Juanatey Stephen B Wilton Wouter J Kikkert Ivan Nunez-Gil Albert Ariza-Sole Dimitrios Alexopoulos Christoph Liebetrau Tetsuma Kawaji Claudio Moretti Zenon Huczek Toshiharu Fujii Luis C Correia Masa-aki Kawashiri Sasko Kedev | 2016 | 中华医学杂志2016，96，33： | 6 |
| 3 | Impact of triple antithrombotic therapy in patients with acute coronary syndrome undergoing percutaneous coronary intervention in real-world practice显示文摘为在急性冠的症候群(交流) 和经皮的冠的干预(一种总线标准) 以后的口头的 anticoagulation (OAC ) 上的病人的 ObjectiveThe 最佳的 antithrombotic 政体仍然保持辩论。寻求回顾地在真实世界的 setting.MethodsWe 评估 OAC 正 clopidogrel 的功效和安全与或没有阿司匹林的这研究分析了数据从一国际,在 2003 和 2014 之间的多中心登记(n = 15,401 ) 。有在一种总线标准以后的交流和收到的 OAC 的病人被屏蔽。合成主要端点是 1 年的所有原因死亡,重新梗塞,或分析注册了 642 个病人包括的严重 bleeding.ResultsThe 期末考试有 OAC 和 clopidogrel (双治疗) 的 62 个病人(9.7%) ,和有阿司匹林, OAC 和 clopidogrel (三倍的治疗) 的联合的 580 个病人(90.3%) 。三倍的治疗上的病人更经常是女性的并且是更可能的有 comorbidities。关于在与三倍的治疗病人一起的双治疗之间的主要结束点没有重要差别[17.74% 对 17.24% ;unadjusted 危险比率(HR ) :1.035;95% 信心间隔(CI ) :0.556-1.929;调整 HR:1.026;95% CI:0.544-1.937 ] 。然而,重新梗塞率比三倍的治疗病人在双治疗是显著地更高的(14.52% 对 5.34% ;unadjusted HR:2.807;95% CI:1.329-5.928;调整 HR:2.333;95% CI:1.078-5.047 ) 。另外,在所有原因死亡和严重 bleeding.ConclusionsIn 的二政体之间没有差别有交流后面的一种总线标准并且与 OAC 的一个指示的真实病人,三倍的治疗没与双治疗相比与不利结果的增加的率被联系。而且,它减少了重新梗塞冒险并且没增加严重流血的风险。 | Yan YAN Xiao WANG Jing-Yao FAN Shao-Ping NIE SerGio Raooseiras-Roubin Emad Abu-Assi Jose P Simao Henriques: Fabrizio D'Ascenzo Jorge Saucedo Jose R Gonzalez-Juanate Stephen B Wilton Wouter J Kikkert Ivan Nunez-Gil Albert Ariza-Sole Xian-Tao SONG Dimitrios Alexopoulos Christoph Liebetrau Tetsuma Kawaji Claudio Morettil Zenon Huczek Toshiharu Fujii Luis cL Correia Masa-aki Kawashiri Sasko Kedev | 2017 | Journal of Geriatric Cardiology2017，14，11： | 6 |
| 4 | Hepatic ischemic preconditioning increases portal vein flow in experimental liver ischemia reperfusion injury显示文摘BACKGROUND: Ischemic preconditioning(IPC) has been shown to decrease liver injury and to increase hepatic microvascular perfusion after liver ischemia reperfusion. This study aimed to evaluate the effects of IPC on hemodynamics of the portal venous system. METHODS: Thirty-two rats were randomized into two groups: IPC group and control group. The rats of the IPC group underwent IPC by 10 minutes of liver ischemia followed by 10 minutes of reperfusion before liver ischemia, and the rats of the control group were subjected to 60 minutes of partial liver ischemia. Non-ischemic lobes were resected immediately after reperfusion. The animals were studied at 4 hours and 12 hours after reperfusion. Mean arterial pressure, heart rate, portal vein flow and pressure were analyzed. Blood was collected for the determination of the levels of aspartate aminotransferase, alanine aminotransferase, calcium, lactate, pH, bicarbonate, and base excess. RESULTS: IPC increased the mean portal vein flow at 4 hours and 12 hours after reperfusion. IPC recovered 78% of the meanportal vein flow at 12 hours after reperfusion. IPC decreased the levels of aspartate aminotransferase, alanine aminotransferase and lactate, and increased the levels of ionized calcium, bicarbonate and base excess at 12 hours after reperfusion. CONCLUSIONS: This study demonstrated that IPC increases portal vein flow and enhances hepatoprotective effects in liver ischemia reperfusion. The better recovery of portal vein flow after IPC may be correlated with the lower levels of transaminases and with the better metabolic profile. | Estela RR Figueira Joel A Rocha-Filho Mauro Nakatani Marcelo FS Buto Eduardo R Tatebe Vitor O Andre Ivan Cecconello Luiz AC D'Albuquerque | 2014 | Hepatobiliary & Pancreatic Diseases International2014，13，1： | 6 |
| 5 | 茶叶中硫丹及硫丹硫酸酯的ELISA快速测定显示文摘研究应用酶联免疫方法,快速检测茶叶中硫丹及硫丹硫酸酯。茶叶提取后,不净化,用PBS缓冲液稀释500倍后,进行酶联免疫方法测定,方法平均回收率为86.6%-91.1%;经SPE净化后,回收率68.7%-123%。标准曲线IC50为2μg/L,线性范围1-10μg/L。直接提取法最低检测限2mg/kg,净化法为0.06mg/kg。经气相色谱/质谱联用方法验证,灵敏度、精密度和准确度均符合快速检测要求。该法具有快速、简便、低耗、易操作等特点。 | 吕潇 任凤山 王文博 杜红霞 李慧冬 丁蕊艳 朱端卫 LEE Nanju A SHEILD Ross KENNEDY Ivan R | 2006 | 茶叶科学2006，26，2： | 5 |
| 6 | Listeria monocytogenes following orthotopic liver transplantation:Central nervous system involvement and review of the literature显示文摘Listeria monocytogene is a well-recognized cause of bacteremia in immunocompromised individuals,including solid organ transplant recipients,but has been rarely reported following orthotopic liver transplantation. We describe a case of listeria meningitis that occurred within a week after liver transplantation. The patient developed a severe headache that mimicked tacrolimus encephalopathy,and was subsequently diagnosed with listeria meningitis by cerebrospinal fluid culture. The infection was successfully treated with three-week course of intravenous ampicillin. Recurrent hepatitis C followed and was successfully treated with interferon alfa and ribavirin. Fourteen cases of listeriosis after orthotopic liver transplantation have been reported in the English literature. Most reported cases were successfully treated with intravenous ampicillin. There were four cases of listeria meningitis,and the mortality of them was 50%. Early detection and treatment of listeria meningitis are the key to obtaining a better prognosis. | Shugo Mizuno Ivan R Zendejas Alan I Reed Robin D Kim Richard J Howard Alan W Hemming Denise C Schain Consuelo Soldevila-Pico Roberto J Firpi Shiro Fujita | 2007 | World Journal of Gastroenterology2007，13，32： | 2 |
| 7 | syndecan-1和-2表达形式的变化可以预测前列腺癌生化复发显示文摘前列腺癌的临床特点不能准确确定患者是否会发生生化复发,因而不适合作为预后和复发的指标。需要新的分子标记物对患者进行适当的术前风险分层。本研究旨在评估syndecan-1和-2的表达改变是否可以预测临床局限性前列腺癌患者行前列腺根治术后的生化复发。取60份局限性前列腺癌患者的石蜡包埋组织标本,采用免疫组化染色检测syndecan-1和-2的表达。取10份良性前列腺增生患者的样本作为非恶性对照。利用半定量分析,对其进行染色评估。为探讨预后效果,用Kaplan—Meier生存曲线进行分析,并进行log—rank检验。在良性前列腺样本中,syndecan-1在基底层上皮细胞中有表达,在上皮分泌细胞的基侧膜上也有表达;syndecan-2则主要但挞底层上皮细胞中表达。前列腺癌样本中,两种syndecan的表达模式都转变成定位在颗粒状细胞质上。生存分析显示,在游离前列腺特异性抗原(fPSA)复发存活曲线中,正常和改变的syndecan-1和-2的表达存在显著差异(P〈0.05)。这些数据表明,syndecan—1和-2可以作为临床局灶性前列腺癌患者预后的标记物,从而改进前列腺特异性抗原(PSA)评估复发风险,增加风险分层。 | Rodrigo Ledezma Federico Cifuentes Ivan Gallegos Juan Fulla Enrique Ossandon Enrique A Castellon Hector R Contreras | 2011 | Asian Journal of Andrology2011，13，3： | 2 |
| 8 | Consumer responses to service failures:influence of procedural and interactional fairness perceptions显示文摘 | CATHY G IVAN R | 1992 | Journal of Business Research1992，25，： | 1 |
| 9 | A new approach for outcrop characterization andgeostatistical analysis of a low-sinuosity fluvial-dominated succession using digital outcrop models:Upper Triassic Oukaimeden sandstone formation,central High Atlas,Morocco显示文摘 | Ivan F David H Jonathan R | 2009 | AAPG Bulletin2009，93，6： | 1 |
| 10 | Glycolyzed poly (ethylene terephthalate) waste and castor oil - based polyols for waterborne polyurethane adhesives containing hexamethoxymethyl melamine显示文摘 | SUZANA M C IVAN S R MILENA M | 2015 | Progress in Organic Coatings2015，78，： | 1 |
| 11 | Activated liver stellate cells in chronic viral C hepatitis:histopathological and immunohistochemical study 显示文摘 | Nada R T Ivan V B Dimitrije C B | 2009 | J Gastrointestin Liver Dis2009，18，2： | 1 |
| 12 | Crystallization and thermal properties in waterborne polyurethane elasto- mers:Influence of mixed soft segment block显示文摘 | SUZANA M C IVAN S R IVAN K | 2014 | Materials Chemistry and Physics2014，144，： | 1 |
| 13 | Carotid artery resection and reconstruction in patients with squamous cell carcinomas of the neck 显示文摘 | Ivan L Paczona R Czigner J | 1999 | Eur Arch Otorhinolaryngol1999，256，3： | 1 |
| 14 | Lignans and other constituents from Carissa edulis显示文摘 | Achenbach H Waibel R Ivan AM 1983 | 1983 | Phytochemistry1983，22，3： | 1 |
| 15 | Co-occurrence of West Nile Fever and circovirus infection in a goose flock in Hungary 显示文摘 | Glavits R Ferenczi E Ivanics E | 2005 | Avian Pathol2005，34，5： | 1 |
| 16 | Four channel, 40 ps resolution, fully integrated time-to-amplitude converter for time-resolved photon counting 显示文摘 | Matteo C Ivan R Massimo G | 2012 | IEEE Journal of Solid-State Circuits2012，47，3： | 1 |
| 17 | MicroRNA regula- tion of DNA repair gene expression in hypexic stress显示文摘 | Crosby ME Kulshreshtha R Ivan M | 2009 | Cancer Res2009，69，3： | 1 |
| 18 | Epidemiology of laryngeal cancer in Osijek - Baranja County( Eastern Croatia) 显示文摘 | Marinela R Nikola K Ivan M | 2012 | Coil Antro- pol2012，36，2： | 1 |
| 19 | Statistical approach for congestion control in gateway touters显示文摘 | Ivan D B Gonzalo R A Bohacek S | 2011 | Computer Networks2011，55，3： | 1 |
| 20 | Coordinated expression of galectin‐3 and caveolin‐1 in thyroid cancer显示文摘 | Jay Shankar Sam M Wiseman Fanrui Meng Katayoon Kasaian Scott Strugnell Alireza Mofid Allen Gown Steven JM Jones Ivan R Nabi | 2012 | J Pathol2012，，1： | 1 |
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