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| 1 | Sentinel Node Mapping for Gastric Cancer: A Prospective Multicenter Trial in Japan显示文摘 | Yuko Kitagawa Hiroya Takeuchi Yu Takagi Shoji Natsugoe Masanori Terashima Nozomu Murakami Takashi Fujimura Hironori Tsujimoto Hideki Hayashi Nobunari Yoshimizu Akinori Takagane Yasuhiko Mohri Kazuhito Nabeshima Yoshikazu Uenosono Shinichi Kinami Junichi S | 2013 | Journal of Clinical Oncology2013，，29： | 11 |
| 2 | New Sentinel Node Mapping Technologies for Early Gastric Cancer显示文摘 | Hiroya Takeuchi Yuko Kitagawa | 2013 | Annals of Surgical Oncology2013，，2： | 5 |
| 3 | Cutting edge of endoscopic full-thickness resection for gastric tumor显示文摘Recently,several studies have reported local full-thickness resection techniques using flexible endoscopy for gastric tumors,such as gastrointestinal stromal tumors,gastric carcinoid tumors,and early gastric cancer(EGC). These techniques have the advantage of allowing precise resection lines to be determined using intraluminal endoscopy. Thus,it is possible to minimize the resection area and subsequent deformity. Some of these methods include:(1) classical laparoscopic and endoscopic cooperative surgery(LECS);(2) inverted LECS;(3) combination of laparoscopic and endoscopic approaches to neoplasia with non-exposure technique; and(4) non-exposed endoscopic wall-inversion surgery. Furthermore,a recent prospective multicenter trial of the sentinel node navigation surgery(SNNS) for EGC has shown acceptable results in terms of sentinel node detection rate and the accuracy of nodal metastasis. Endoscopic full-thickness resection with SNNS is expected to become a treatment option that bridges the gap between endoscopic submucosal dissection and standard surgery for EGC. In the future,the indications for these procedures for gastric tumors could be expanded. | Tadateru Maehata Osamu Goto Hiroya Takeuchi Yuko Kitagawa Naohisa Yahagi | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，16： | 4 |
| 4 | Current status and challenges in sentinel node navigation surgery for early gastric cancer显示文摘As an optimal surgical procedure to accurately evaluate lymph node(LN)metastasis during surgery with minimal surgical resection,we have been developing sentinel node(SN)biopsy for early gastric cancer since the 1990s.Twelve institutions from the Japanese Society of Sentinel Node Navigation Surgery(SNNS),including Keio University Hospital,conducted a multicenter prospective trial to validate the SN concept using the dual-tracer method with blue dye and a radioisotope.According to the results,397 patients were included in the final analysis,and the overall accuracy in detecting LN metastasis using SN biopsy was 99%(383 of 387).Based on the validation study,we are targeting cT1N0 with a primary tumor of≤4 cm in diameter as an indication for SN biopsy for gastric cancer.We are currently running a multicenter nonrandomized phaseⅢtrial to assess the safety and efficacy of SN navigation surgery.The Korean group has reported the result of a multicenter randomized phaseⅢtrial.Since meticulous gastric cancer in the remnant stomach was rescued by subsequent gastrectomy,the disease-specific survival was comparable between the two techniques,implying that SN navigation surgery can be an alternative to standard gastrectomy.With the development of SN biopsy procedure and treatment modalities,the application of SN biopsy will be expanded to achieve an individualized minimally invasive surgery. | Satoru Matsuda Tomoyuki Irino Hirofumi Kawakubo Hiroya Takeuchi Yuko Kitagawa | 2021 | Chinese Journal of Cancer Research2021，33，2： | 3 |
| 5 | 日本图书馆学信息学专业教育的现状及问题显示文摘日本有2000多所大专院校根 据图书馆法的要求开设20学分制的图书馆 学课程,并每年为该国培养上万名合格的 图书馆员。日本文部省负责图书馆员教育 和资历的管理工作,并为符合图书馆法要 求的图书馆员颁发不同级别的资历证书。 该国有9所四年制的大学设有图书馆学信 息学的专门系别或方向。尽管如此,日本 的图书馆学信息学专业的发展仍然不够健 全。 | Hiroya Takeuchi Yong Won Kim 肖永英 | 2001 | 图书馆理论与实践2001，，1： | 3 |
| 6 | Current status of minimally invasive esophagectomy for patients with esophageal cancer显示文摘 | Hiroya Takeuchi Hirofumi Kawakubo Yuko Kitagawa | 2013 | General Thoracic and Cardiovascular Surgery2013，，： | 2 |
| 7 | Multicenter study evaluating the clinical performance of the OSNA assay for the molecular detection of lymph node metastases in gastric cancer patients显示文摘 | Koshi Kumagai Noriko Yamamoto Isao Miyashiro Yasuhiko Tomita Hitoshi Katai Ryoji Kushima Hitoshi Tsuda Yuko Kitagawa Hiroya Takeuchi Makio Mukai Masayuki Mano Hidetaka Mochizuki Yo Kato Nariaki Matsuura Takeshi Sano | 2014 | Gastric Cancer2014，，2： | 2 |
| 8 | Gastric carcinogenesis and the cancer stem cell hypothesis显示文摘 | Yoshiro Saikawa Kazumasa Fukuda Tsunehiro Takahashi Rieko Nakamura Hiroya Takeuchi Yuko Kitagawa | 2010 | Gastric Cancer2010，，1： | 1 |
| 9 | Association of anastomotic leakage with long-term oncologic outcomes of patients with esophagogastric junction cancer显示文摘BACKGROUND Despite improvements in surgical procedures and peri-operative patients management,the postoperative complications in esophagogastric junction(EGJ)cancer remain high because of technical aspects.Several studies have indicated the negative influence of postoperative infectious complications on long-term survival after gastrointestinal surgery.However,no study has shown the association between postoperative complications and long-term survival of patients with EGJ cancer.AIM To elucidate influence of postoperative complications on the long-term outcomes of patients with EGJ cancer.METHODS A total of 122 patients who underwent surgery for EGJ cancer at the Keio University were included in this study.We examined the association between complications and long-term oncologic outcomes.RESULTS In all patients,the 3-year overall survival(OS)rate was 71.9%,and the recurrencefree survival(RFS)rate was 67.5%.Compared with patients without anastomotic leakage,those with anastomotic leakage had poor median OS(8 mo vs not reached,P=0.028)and median RFS(5 mo vs not reached,P=0.055).Among patients with cervical anastomosis,there were not significant differences between patients with and without anastomotic leakage.However,among patients who underwent intrathoracic anastomosis,patients with anastomotic leakage had significantly worse OS(P=0.002)and RFS(P=0.005).CONCLUSION Anastomotic leakage was significantly associated with long-term oncologic outcomes of patients with EGJ cancer,especially those who underwent intrathoracic anastomosis.Cervical anastomosis with subtotal esophagectomy may be an option for the patients who are at high risk for anastomotic leakage. | Masashi Takeuchi Hirofumi Kawakubo Satoru Matsuda Shuhei Mayanagi Tomoyuki Irino Jun Okui Kazumasa Fukuda Rieko Nakamura Norihito Wada Hiroya Takeuchi Yuko Kitagawa | 2022 | World Journal of Gastrointestinal Surgery2022，14，1： | 1 |
| 10 | X-Linked InhibitorofApoptosis Protein Expression Level in Colorectal Cancer Is Regulated by Hepatocyte Growth Factor/C-Met Pathway via Akt Signaling显示文摘 | Hiroya Takeuchi Joseph Kim Akihide Fujimoto | 2005 | Clin Cancer Res2005，11，21： | 1 |
| 11 | New Sentinel Node Mapping Technologies for Early Gastric Cancer显示文摘 | Hiroya Takeuchi Yuko Kitagawa | 2013 | Annals of Surgical Oncology2013，，2： | 1 |
| 12 | Is Lymphadenectomy a Predictor or Savior for Patients with Gastric Cancer?显示文摘 | Hiroya Takeuchi Yuko Kitagawa | 2010 | Annals of Surgical Oncology2010，，5： | 1 |
| 13 | Molecular Detection of Sentinel Node Micrometastases in Patients with Clinical N0 Gastric Carcinoma with Real-time Multiplex Reverse Transcription-Polymerase Chain Reaction Assay显示文摘 | Yoshimasa Shimizu MD Hiroya Takeuchi MD PhD Yasuhiko Sakakura PhD Yoshiro Saikawa MD PhD Tadaki Nakahara MD PhD Makio Mukai MD PhD Masaki Kitajima MD PhD Yuko Kitagawa MD PhD | 2012 | Annals of Surgical Oncology2012，，2： | 1 |
| 14 | Protective Effect of High-Mobility Group Box 1 Blockade on Acute Liver Failure in Rats显示文摘 | Kiminori Takano Masahiro Shinoda Minoru Tanabe Taku Miyasho Shingo Yamada Shigeshi Ono Yohei Masugi Koichi Suda Koichi Fukunaga Tetsu Hayashida Taizo Hibi Hideaki Obara Hiroya Takeuchi Shigeyuki Kawachi Kazufumi Kawasako Minoru Okamoto Hiroshi Yokota Ikur | 2010 | Shock2010，，6： | 1 |
| 15 | Clinical Significance of Circulating Tumor Cells in Blood from Patients with Gastrointestinal Cancers显示文摘 | Kunihiko Hiraiwa MD Hiroya Takeuchi MD PhD Hirotoshi Hasegawa MD PhD Yoshiro Saikawa MD PhD Koichi Suda MD PhD Takashi Ando MD Koshi Kumagai MD Tomoyuki Irino MD Takahisa Yoshikawa MD Sachiko Matsuda PhD Masaki Kitajima MD PhD Yuko Kitagawa MD PhD | 2008 | Annals of Surgical Oncology2008，，11： | 1 |
| 16 | Validation Study of Radio-Guided Sentinel Lymph Node Navigation in Esophageal Cancer显示文摘 | Hiroya Takeuchi Hirofumi Fujii Nobutoshi Ando Soji Ozawa Yoshiro Saikawa Koichi Suda Takashi Oyama Makio Mukai Tadaki Nakahara Atsushi Kubo Masaki Kitajima Yuko Kitagawa | 2009 | Annals of Surgery2009，，5： | 1 |
| 17 | Molecular Detection of Sentinel Node Micrometastases in Patients with Clinical N0 Gastric Carcinoma with Real-time Multiplex Reverse Transcription-Polymerase Chain Reaction Assay显示文摘 | Yoshimasa Shimizu Hiroya Takeuchi Yasuhiko Sakakura Yoshiro Saikawa Tadaki Nakahara Makio Mukai Masaki Kitajima Yuko Kitagawa | 2012 | Annals of Surgical Oncology2012，，2： | 1 |
| 18 | Gastric carcinogenesis and the cancer stem cell hypothesis显示文摘 | Yoshiro Saikawa Kazumasa Fukuda Tsunehiro Takahashi Rieko Nakamura Hiroya Takeuchi Yuko Kitagawa | 2010 | Gastric Cancer2010，，1： | 1 |
| 19 | Initial experience of individualized chemoradiotherapy for superficial esophageal cancers based on the sentinel lymph node concept显示文摘 | TAKUJI kaburagi TAKEUCHI Hiroya FUJII Hirofumi | 2012 | Esophagus2012，9，3： | 1 |
| 20 | Sentinel Node Mapping in Adenocarcinoma of the Esophagogastric Junction显示文摘 | Tatsuo Matsuda Hiroya Takeuchi Shinichi Tsuwano Tadaki Nakahara Makio Mukai Yuko Kitagawa | 2014 | World Journal of Surgery2014，，9： | 1 |
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