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| 1 | Transjugular intrahepatic portosystemic shunt for the management of acute variceal hemorrhage显示文摘Acute variceal hemorrhage,a life-threatening condition that requires a multidisciplinary approach for effective therapy,is defined as visible bleeding from an esophageal or gastric varix at the time of endoscopy,the presence of large esophageal varices with recent stigmata of bleeding,or fresh blood visible in the stomach with no other source of bleeding identified.Transfusion of blood products,pharmacological treatments and early endoscopic therapy are often effective;however,if primary hemostasis cannot be obtained or if uncontrollable early rebleeding occurs,transjugular intrahepatic portosystemic shunt(TIPS)is recommended as rescue treatment.The TIPS represents a major advance in the treatment of complications of portal hypertension.Acute variceal hemorrhage that is poorly controlled with endoscopic therapy is generally well controlled with TIPS,which has a 90%to 100%success rate.However,TIPS is associated with a mortality of 30%to 50%in such a setting.Emergency TIPS should be considered early in patients with refractory variceal bleeding once medical treatment and endoscopic sclerotherapy failure,before the clinical condition worsens.Furthermore,admission to specialized centers is mandatory in such a setting and regional protocols are essential to be organized effectively.This review article discusses initial management and then focuses on the specific role of TIPS as a primary therapy to control acute variceal hemorrhage,particularly as a rescue therapy following failure of endoscopic approaches. | Romaric Loffroy Louis Estivalet Violaine Cherblanc Sylvain Favelier Pierre Pottecher Samia Hamza Anne Minello Patrick Hillon Pierre Thouant Pierre-Henri Lefevre Denis Krausé Jean-Pierre Cercueil | 2013 | World Journal of Gastroenterology2013，19，37： | 25 |
| 2 | Propranolol for prevention of recurrent gastrointestinal bleeding in patients with cirrhosis 显示文摘 | Lebrec D Poynard T Hillon P | 1981 | N Engl J Med1981，305，： | 1 |
| 3 | Effect of high-dose dexamethasone in prednisone-resistant antoimmune thrombocytopenic purpura(ITP)显示文摘 | Van der Heul C Hillon HF | 1991 | Neth J Med1991，39，6： | 1 |
| 4 | The effect of propra- nolol on portal hypertension in patients with cirrhosis: a hemody- namic study显示文摘 | LEBREC D HILLON P MU?OZ C | 1982 | Hepatology1982，2，5： | 1 |
| 5 | Diffuse alveolar hemorrhage and pulmonary capillaritis due to propylthiouracil 显示文摘 | Hillon S S Singh D Doe N | 1999 | Chest1999，116，5： | 1 |
| 6 | C-terminal provasopressin (copeptin) as a novel and prognostic marker in acute myocardial infarction: Leicester Acute Myocardial Infarction Peptidc (LAMP) study 显示文摘 | Khan SQ 1)hillon OS Quinn PA | 2007 | Circulation2007，115，16： | 1 |
| 7 | A preliminarycommunication on whether general dental practitioners have arole in identifying dental patients with mental health problems显示文摘 | Lloyd - Williams F Dowrick C Hillon D | 2001 | Br Dent J2001，191，11： | 1 |
| 8 | Propranolol for prevention of gastrointestinal bleeding in patients with cirrhosis显示文摘 | Lebrec D Poynard T Hillon P | 1981 | N Engl J Med1981，305，： | 1 |
| 9 | Obesity, type 2 diabetes and risk of digestive cancer显示文摘 | P. Hillon B. Guiu J. Vincent J.-M. Petit | 2010 | Gastroenterologie Clinique et Biologique2010，，10： | 1 |
| 10 | Lack of association between microsomal triglyceride transfer protein gene polymorphism and liver steatosis in HCV-infected patients显示文摘 | Jean Michel Petit David Masson Anne Minello Laurence Duvillard Francoise Galland Bruno Verges Philippe Gambert Patrick Hillon | 2005 | Molecular Genetics and Metabolism2005，，2： | 1 |
| 11 | Propranolol for prevention of recurrent gastrointestinal bleeding in patients with cirrhosis, a prospective study of factors associated with rebleeding显示文摘 | POYNARD T LEBREC D HiLLON P | 1977 | Hepatology1977，7，3： | 1 |
| 12 | Phase II trial of curcumin in patients with advanced pancreatic cancer显示文摘 | hillon N Aggarwal BB Newman RA | | 0，，14： | 1 |
| 13 | Risk factors for diabetes mellitus and early insulin resistance in chronic hepatitis C显示文摘 | Jean-Michel Petit Jean-Baptiste Bour Catherine Galland-Jos Anne Minello Bruno Verges Michel Guiguet Jean-Marcel Brun Patrick Hillon | 2001 | Journal of Hepatology2001，，2： | 1 |
| 14 | Mapping of liver fat with triple-echo gradient echo imaging: validation against 3.0-T proton MR spectroscopy显示文摘 | Boris Guiu Romaric Loffroy Jean-Michel Petit Serge Aho Douraied Ben Salem David Masson Patrick Hillon Jean-Pierre Cercueil Denis Krause | 2009 | European Radiology2009，，7： | 1 |
| 15 | Risk factors for diabetes mellitus and early insulin resistance in chronic hepatitis C显示文摘 | Jean-Michel Petit Jean-Baptiste Bour Catherine Galland-Jos Anne Minello Bruno Verges Michel Guiguet Jean-Marcel Brun Patrick Hillon | 2001 | Journal of Hepatology2001，，2： | 1 |
| 16 | Intravoxel Incoherent Motion Diffusion-weighted Imaging in Nonalcoholic Fatty Liver Disease: A 3.0-T MR Study显示文摘 | Boris Guiu Jean-Michel Petit Violaine Capitan Serge Aho David Masson Pierre-Henri Lefevre Sylvain Favelier Romaric Loffroy Bruno Vergès Patrick Hillon Denis Krausé Jean-Pierre Cercueil | 2012 | Radiology2012，，1： | 1 |
| 17 | Predictive factors of alcohol relapse after orthotopic liver transplantation for alcoholic liver disease显示文摘 | Mathieu Miguet Elisabeth Monnet Claire Vanlemmens Pascal Gache Michel Messner Stephane Hruskovsky Jean Marc Perarnau Georges-Philippe Pageaux Christophe Duvoux Anne Minello Patrick Hillon Solange Bresson-Hadni Georges Mantion Jean-Philippe Miguet | 2004 | Gastroenterologie Clinique et Biologique2004，，10： | 1 |
| 18 | Analysis and optimiz a tio n o fn a n o m e te rC M O S e irc u its fo rs o ft-e rro rto le rance显示文摘 | D hillon Y S D iril A U Chatteijee A | 2006 | IEEE Transactions on Very Large Scale IntegrationSystems2006，14，5： | 1 |
| 19 | Cyclin E overexpression enhances cytokine - mediated apoptosis in MCF7 breast cancer cells显示文摘 | hillon NK Mudryj M | 2003 | Genes Immun2003，4，： | 1 |
| 20 | 丙型肝炎患者的治疗:法国一项人群研究 | Hatem C. Minello A. Martin L. P. Hillon 陈云茹 | 2005 | 世界核心医学期刊文摘(胃肠病学分册)2005，0，6： | 0 |
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