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| 1 | An Exploration of Deep-Learning Based Phenotypic Analysis to Detect Spike Regions in Field Conditions for UK Bread Wheat显示文摘Wheat is one of the major crops in the world,with a global demand expected to reach 850 million tons by 2050 that is clearly outpacing current supply.The continual pressure to sustain wheat yield due to the world’s growing population under fluctuating climate conditions requires breeders to increase yield and yield stability across environments.We are working to integrate deep learning into field-based phenotypic analysis to assist breeders in this endeavour.We have utilised wheat images collected by distributed CropQuant phenotyping workstations deployed for multiyear field experiments of UK bread wheat varieties.Based on these image series,we have developed a deep-learning based analysis pipeline to segment spike regions from complicated backgrounds.As a first step towards robust measurement of key yield traits in the field,we present a promising approach that employ Fully Convolutional Network(FCN)to performsemantic segmentation of images to segment wheat spike regions.We also demonstrate the benefits of transfer learning through the use of parameters obtained from other image datasets.We found that the FCN architecture had achieved a Mean classification Accuracy(MA)>82%on validation data and>76%on test data and Mean Intersection over Union value(MIoU)>73%on validation data and and>64%on test datasets.Through this phenomics research,we trust our attempt is likely to form a sound foundation for extracting key yield-related traits such as spikes per unit area and spikelet number per spike,which can be used to assist yield-focused wheat breeding objectives in near future. | Tahani Alkhudaydi Daniel Reynolds Simon Griffiths Ji Zhou Beatriz de la Iglesia | 2019 | Plant Phenomics2019，1，1： | 5 |
| 2 | Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial显示文摘 | David Sebag-Montefiore Richard J Stephens Robert Steele John Monson Robert Grieve Subhash Khanna Phil Quirke Jean Couture Catherine de Metz Arthur Sun Myint Eric Bessell Gareth Griffiths Lindsay C Thompson Mahesh Parmar | 2009 | The Lancet2009，，9666： | 5 |
| 3 | The chemosensory appendage proteome of Amblyomma americanum (Acari: Ixodidae) reveals putative odorant-binding and other chemoreception-related proteins显示文摘Proteomic 分析在孤独的星的 2 个化学感应的附器上被做滴答响, Amblyomma americanum。蛋白质在在先 tarsi,包含嗅觉的 Hallers 机关,并且在触官,包括味觉的 sensilla,与在第三 tarsi 的蛋白质相比。另外,男性和女性滴答响被比较。蛋白质被顺序类似,并且由 3-dimensional 相同建模识别到已知的蛋白质。Proteomic 数据也与从 tick Rhipicephalus microplus 的器官特定的 transcriptomes 相比。在先 tarsi 快车没在第三 tarsi 或触官发现的 lipocalin。在先, tarsi 和触官富有地表示 2 蛋白质,它类似于昆虫有气味的东西绑定蛋白质(OBP ) 。与昆虫 OBP 相比, tick 象 OBP 一样序列缺乏半胱氨酸在 C 减 OBP 不在,并且 1 滴答响象 OBP 一样顺序有类似于 C 加 OBP 的另外的半胱氨酸。类似于抗菌素蛋白质 microplusin 的四蛋白质被发现:2 只表示了在在先 tarsi 并且 1 只在触官表示了。这些蛋白质缺乏 microplusin 铜绑定地点,而是他们被建模有一个重要的内部洞,潜在地一个 ligand 有约束力的地点。类似于 7 被发现差别的灰尘螨变应原 Der p7 和 Der f 的蛋白质在先在女性表示了 tarsi。只表示在的蛋白质在先, tarsi 有类似到否决权,它被知道涉及 ionotropic glutamate 受体聚类。这些结果组成象 OBP 一样蛋白质序列的第一份报告在滴答响并且点到几条研究大街在上滴答响化学感应的接收。 | Robert Renthal Leena Manghnani Sandra Bernal Yanyan Qu Wendell P. Griffith Kim Lohmeyer Felix O. Guerrero Ligia M.F. Borges Adalberto Perez de Leon | 2017 | Insect Science2017，24，5： | 4 |
| 4 | Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial显示文摘 | David Sebag-Montefiore Richard J Stephens Robert Steele John Monson Robert Grieve Subhash Khanna Phil Quirke Jean Couture Catherine de Metz Arthur Sun Myint Eric Bessell Gareth Griffiths Lindsay C Thompson Mahesh Parmar | 2009 | The Lancet2009，，9666： | 3 |
| 5 | Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial显示文摘 | David Sebag-Montefiore Richard J Stephens Robert Steele John Monson Robert Grieve Subhash Khanna Phil Quirke Jean Couture Catherine de Metz Arthur Sun Myint Eric Bessell Gareth Griffiths Lindsay C Thompson Mahesh Parmar | 2009 | The Lancet . 2009 (9666)2009，，9666： | 3 |
| 6 | An official ATS/IDSA statement:diagnosis,treatment,and prevention of nontuberculous mycobacterial diseases显示文摘 | Griffith DE Aksamit T Brown-Elliott BA | | 0，，04： | 1 |
| 7 | The potato P locus codes for flavonoid 3',5'-hydroxylase显示文摘 | Jung C S Griffiths H M De Jong D M | 2005 | Theoretical and Applied Genetics2005，110，： | 1 |
| 8 | An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobaeterial diseases 显示文摘 | Griffith DE Aksamit T Brown-Elliott BA | 2007 | Am J Respir Crit Care Med2007，175，4： | 1 |
| 9 | Development, Validation, and Evaluation of a Pediatric Ulcerative Colitis Activity Index: A Prospective Multicenter Study显示文摘 | Dan Turner Anthony R. Otley David Mack Jeffrey Hyams J. de Bruijne Krista Uusoue Thomas D. Walters Mary Zachos Petar Mamula Dorcas E. Beaton A. Hillary Steinhart Anne M. Griffiths | 2007 | Gastroenterology2007，，2： | 1 |
| 10 | An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobaclerial diseases显示文摘 | Griffith DE Aksamil T Brown Elliott BA | 2007 | Am J Respir Crit Care Med2007，75，4： | 1 |
| 11 | The potato plocus codes for flavonoid 3',5'-hydroxylase 显示文摘 | JUNG C S GRIFFITHS H M DE JONG D M | 2005 | Theor Appl Genet2005，110，： | 1 |
| 12 | Pharmacokinetics and safety of MP-376 (levofloxaein inhalation solution ) in cystic fibrosis subjects 显示文摘 | Geller DE Flume PA Griffith DC | 2011 | Antimicrob Agents Chemother2011，55，6： | 1 |
| 13 | Diagnosis, treatment, and prevention of nontuberculous myeobaeterial diseases显示文摘 | Griffith DE Aksamit T Brown-Elliott BA | 2007 | AmJ RespirCrit CareMed2007，175，： | 1 |
| 14 | An offical ATS/IDSA statement:diagnosis,treatment,and prevention of nontuberculous mycobacte-rial diseases 显示文摘 | Griffith DE Aksamit T Brown-Elliott BA | 2007 | American Journal of Respiratory and Critical Care Medicine2007，175，4： | 1 |
| 15 | T-loop assembly in vitro involves binding of TRF2 near the 3'telomeric overhang J显示文摘 | Stansel RM De Lange T Griffith JD | 2001 | EMBO J2001，20，19： | 1 |
| 16 | Early results (at 6 months )with intermittent clarithromycin-including regimens for lung disease due to Mycobacterium mium complex显示文摘 | Griffith DE Brown BA Cegielski P | 2000 | Clin Infect Dis2000，30，2： | 1 |
| 17 | Nosocomial outbreaks / pseudo-outbreaks caused by nontuberculous mycobacteria显示文摘 | Wallace RJ Jr Brown BA Griffith DE | | 0，，： | 1 |
| 18 | An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases显示文摘 | Griffith DE Aksamit T Brown-Elliott BA | 2007 | Am J Respir Crit Care Med2007，175，4： | 1 |
| 19 | Adaptation to the Intensive Care Environment (ATICE) :development and validation of a new sedation as- sessment instrument显示文摘 | De Jonghe B Cook D Griffith L | 2003 | Crit Care Med2003，31，9： | 1 |
| 20 | An official ATS/IDSA statement: diagnosis, treatment, and prevention ofnontuberculous mycobacterial diseases显示文摘 | Griffith DE Aksamit T Brown-Elliott BA | 2007 | Am J Respir Crit CareMed2007，175，4： | 1 |
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