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| 1 | Long-term safety of lamivudine treatment in patients with chronic hepatitis B显示文摘 | Anna S.F Lok Ching-Lung Lai Nancy Leung Guang-Bi Yao Zhen-Yu Cui Eugene R Schiff Jules L Dienstag E.Jenny Heathcote Nancy R Little Dorothea A Griffiths Stephen D Gardner Mary Castiglia | 2003 | Gastroenterology2003，，6： | 3 |
| 2 | Conduit necrosis following esophagectomy: An up-to-date literature review显示文摘Esophageal conduit ischaemia and necrosis is an uncommon but devastating complication of esophagectomy and remains one of the most challenging issues in surgical practice. The incidence, time interval to develop symptoms, and clinical presentation are highly variable with no predictable pattern. Evidence comes from case reports and case series rather than randomized controlled trials.We describe the issues surrounding conduit necrosis affecting the stomach,jejunum and colon as an esophageal replacement and the advantages,disadvantages and challenges of each type of reconstruction. Diagnosis is challenging for the most experienced surgeon. Upper gastrointestinal endoscopy and computed tomography thorax with both oral and intravenous contrast is the gold standard. Management, either conservative or interventional is also a difficult decision. Management options include conservative treatment and more aggressive treatments such as stent insertion, surgical debridement and repair of the esophagus using jejunum, colon or a musculocutaneous flap. In spite of recent advances in surgical techniques, there is no reliable strategy to manage esophageal conduit necrosis. Our review covers the pathophysiology and clinical significance of esophageal necrosis while highlighting current techniques of prevention, diagnosis and treatment of this life-threatening condition. | Antonios Athanasiou Mairead Hennessy Eleftherios Spartalis Benjamin H L Tan Ewen A Griffiths | 2019 | World Journal of Gastrointestinal Surgery2019，11，3： | 2 |
| 3 | Long-term safety of lamivudine treatment in patients with chronic hepatitis B显示文摘 | Anna S.F Lok Ching-Lung Lai Nancy Leung Guang-Bi Yao Zhen-Yu Cui Eugene R Schiff Jules L Dienstag E.Jenny Heathcote Nancy R Little Dorothea A Griffiths Stephen D Gardner Mary Castiglia | 2003 | Gastroenterology2003，，6： | 2 |
| 4 | SLC26A4 mutation testing for hearing loss associated with enlargement of the vestibular aqueduct显示文摘Pendred syndrome(PS) is characterized by autosomal recessive inheritance of goiter associated with a defect of iodide organification, hearing loss, enlargement of the vestibular aqueduct(EVA), and mutations of the SLC26A4 gene. However, not all EVA patients have PSor SLC26A4 mutations. Two mutant alleles of SLC26A4 are detected in 1/4 of North American or European EVA populations, one mutant allele is detected in another 1/4 of patient populations, and no mutations are detected in the other 1/2. The presence of two mutant alleles of SLC26A4 is associated with abnormal iodide organification, increased thyroid gland volume, increased severity of hearing loss, and bilateral EVA. The presence of a single mutant allele of SLC26A4 is associated with normal iodide organification, normal thyroid gland volume, less severe hearing loss and either bilateral or unilateral EVA. When other underlying correlations are accounted for, the presence of a cochlear malformation or the size of EVA does not have an effect on hearing thresholds. This is consistent with observations of an Slc26a4 mutant mouse model of EVA in which hearing loss is independent of endolymphatic hydrops or inner ear malformations. Segregation analyses of EVA in families suggest that the patients carrying one mutant allele of SLC26A4 have a second, undetected mutant allele of SLC26A4, and the probability of a sibling having EVA is consistent with its segregation as an autosomal recessive trait. Patients without any mutations are an etiologically heterogeneous group in which siblings have a lower probability of having EVA. SLC26A4 mutation testing can provide prognostic information to guide clinical surveillance and management, as well as the probability of EVA affecting a sibling. | Taku Ito Julie Muskett Parna Chattaraj Byung Yoon Choi Kyu Yup Lee Christopher K Zalewski Kelly A King Xiangming Li Philine Wangemann Thomas Shawker Carmen C Brewer Seth L Alper Andrew J Griffith | 2013 | World Journal of Otorhinolaryngology2013，3，2： | 2 |
| 5 | Virtu-alness and Knowledge in Teams:Managing the Love Triangle of Organizations,Individuals,And Information Technology 显示文摘 | GRIFFITH T L SAWYER J E NEALE M A | 2003 | MIS Quarterly2003，，2： | 1 |
| 6 | Characterization of antifreeze activity in antarctic plants显示文摘 | BRAVO L A GRIFFITH M | 2005 | Journal of Experimental Botany2005，56，414： | 1 |
| 7 | Flow cytometry analysis of gingival and periodontal ligament cells显示文摘 | Kuru L Parkar MH Griffiths GS | 1998 | J Dent Res1998，77，4： | 1 |
| 8 | Isoniazid prophylaxis for tuberculosis in HIV infection:a meta analysis of randomized controlled trials显示文摘 | Bucher H C Griffith L Guyatt G | 1999 | AIDS1999，13，： | 1 |
| 9 | Outbursts and mines: A review显示文摘 | Shepherd J Rixon L K geological structure in coal Griffiths L | 1981 | Int J Rock Mech Min Sei Geomeb Abstr1981，18，4： | 1 |
| 10 | The Canadian Critical Trials Group显示文摘 | Heyland DK Cook DJ Griffith L et aL The attributable morbidity and mortality of ventilator-associated pneumonia in the critically ill patient | 1999 | American Journal of Respiratory and Critical Care Medicine1999，159，41： | 1 |
| 11 | Regulation of mitotic en-try by microcephalin and its overlap with ATR signalling显示文摘 | Alderton GK Galbiati L Griffith E | 2006 | Nat Cell Biol2006，8，7： | 1 |
| 12 | Relationships between size, mantle area and zooxanthellae numbers in five species of giant clam Cf'ridacnidae)显示文摘 | Griffiths C L Klumpp D W | 1997 | Oceanographic Literature Review1997，44，2： | 1 |
| 13 | Probabilistic topic models 显示文摘 | Steyvers M Griffiths T L | 2007 | Handbook of Latent Semantic Analysis2007，427，7： | 1 |
| 14 | Stability of earth slopes, part II: three dimensional analysis in closed-form显示文摘 | PANTELIDIS L GRIFFITHS D V | 2013 | International Journal for Numerical and Analytical Methods in Geomechanies2013，37，13： | 1 |
| 15 | Why New Technologies Fail显示文摘 | Griffith T L Zammuto R F Aiman-Smith L | 1999 | Industrial Management1999，41，3： | 1 |
| 16 | Platelet-derived endothelial cell growth factor thymidine phosphorylase in tumour growth and response to therapy显示文摘 | Griffiths L Stratford I J | 1997 | Br J Cancer1997，76，6： | 1 |
| 17 | Adaptive antenna Sys-tems显示文摘 | Widrow B Mantey PE Griffiths L J | 1967 | Prpceedings of the IEEE1967，55，12： | 1 |
| 18 | Mammalian telomeres end in a large duplex loop显示文摘 | Griffith JD Comeau L Rosenfield S | 1995 | Ce111995，97，4： | 1 |
| 19 | Lipid productivity as a key characteristic for choosing algal species for biodiesel production显示文摘 | Griffiths M J Harrison S T L | 2009 | J Appl Phyco12009，21，： | 1 |
| 20 | The evolutionary ecology of seed germination of Arabidopsis thaliana : Variable natural selec- tion on germination timing显示文摘 | Donohue K Dora L Griffith C etal | 2005 | Evolution2005，59，4： | 1 |
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