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| 1 | The definition and classification of dry eye disease:report of the Definition and Classification Subcommittee of the International Dry Eye Workshop(2007)显示文摘 | Michael AL Baudouin C Gary NF | 2007 | Ocul Surf2007，5，2： | 1 |
| 2 | Controlled precipitation by thermal engineered laser shock peening and its effect on dislocation pinning: Multiseale dislocation dynamics simulation and experiments显示文摘 | Yiliang Liao Gary J Cheng et aL | 2013 | Acta Materialia2013，61，6： | 1 |
| 3 | Failure mode and effects analysis using a group-based ev- idential reasoning approach 显示文摘 | Kwai-Sang Chin Ying-Ming Wang Gary Ka Kwai Poon et al | 2009 | Computers Operations Re- search2009，，36： | 1 |
| 4 | Effect of Glucose Intolerance on Myocardial Function and Collagen- Linked Glycation Diabetes显示文摘 | Gary F Avendano Ramesh K vt al | 1999 | July1999，48，7： | 1 |
| 5 | Knowledge networks in new product development projects:a transactive memory perspective显示文摘 | AL I E AKGUN JOHN BYRNE HAL IT KESKIN GARY S LYNN SAL IH Z IMAMOGLU | | 0，，： | 1 |
| 6 | Effectiveness, safety, and drug sustainability of biologics in elderly patients with inflammatory bowel disease: A retrospective study显示文摘BACKGROUND Biologic therapy resulted in a significant positive impact on the management of inflammatory bowel disease(IBD) however data on the efficacy and side effects of these therapies in the elderly is scant.AIM To evaluate retrospectively the drug sustainability, effectiveness, and safety of the biologic therapies in the elderly IBD population.METHODS Consecutive elderly(≥ 60 years old) IBD patients, treated with biologics [infliximab(IFX), adalimumab(ADAL), vedolizumab(VDZ), ustekinumab(UST)] followed at the McGill University Inflammatory Bowel Diseases Center were included between January 2000 and 2020.Efficacy was measured by clinical scores at 3, 6-9 and 12-18 mo after initiation of the biologic therapy. Patients completing induction therapy were included. Adverse events(AEs) or serious AE were collected during and within three months of stopping of the biologic therapy.RESULTS We identified a total of 147 elderly patients with IBD treated with biologicals during the study period, including 109 with Crohn’s disease and 38 with ulcerative colitis. Patients received the following biologicals: IFX(28.5%), ADAL(38.7%), VDZ(15.6%), UST(17%). The mean duration of biologic treatment was 157.5(SD = 148) wk. Parallel steroid therapy was given in 34% at baseline,19% at 3 mo, 16.3% at 6-9 mo and 6.5% at 12-18 mo. The remission rates at 3, 6-9 and 12-18 mo were not significantly different among biological therapies. Kaplan-Meyer analysis did not show statistical difference for drug sustainability(P = 0.195), time to adverse event(P = 0.158) or infection rates(P = 0.973) between the four biologics studied. The most common AEs that led to drug discontinuation were loss of response, infusion/injection reaction and infection.CONCLUSION Current biologics were not different regarding drug sustainability, effectiveness, and safety in the elderly IBD population. Therefore, we are not able to suggest a preferred sequencing order among biologicals. | Gustavo Drugg Hahn Jean-Frederic LeBlanc Petra Anna Golovics Panu Wetwittayakhlang Abdulrahman Qatomah Anna Wang Levon Boodaghians Jeremy Liu Chen Kiow Maryam Al Ali Gary Wild Waqqas Afif Alain Bitton Peter Laszlo Lakatos Talat Bessissow | 2022 | World Journal of Gastroenterology2022，28，33： | 1 |
| 7 | Carbohydraterestricted diets high in either monounsaturated fat or protein are equally effective at promoting fat loss and improving blood lipids显示文摘 | Natalie DL Manny N Gary AW at al | 2005 | Am J Clin Nutr2005，81，： | 1 |
| 8 | Alcohol and mortality显示文摘 | Klatsky AL Armstrong MA Gary D | 1992 | Ann Intern Med1992，117，8： | 1 |
| 9 | 90Y Radioembolization for Metastatic Neuroendocrine Liver Tumors: Preliminary Results From a Multi-institutional Experience显示文摘 | Thomas K. Rhee Robert J. Lewandowski David M. Liu Mary F. Mulcahy Gary Takahashi Paul D. Hansen Al B. Benson Andrew S. Kennedy Reed A. Omary Riad Salem | 2008 | Annals of Surgery2008，，6： | 1 |
| 10 | Genipininduced changes in collagen gels:Correlation of mechanical properties to fluorescence显示文摘 | Harini GS Gary AM Norman AL | 2008 | J Biomed Mater Res A2008，87，2： | 1 |
| 11 | A MEMS radio-frequency ion mobility spectrometer for chemical vapor detection显示文摘 | Raanan A Miller Erkinjon G Nazarov Gary A Eiceman et al | 2001 | Sensors and Actuators A2001，91，3： | 1 |
| 12 | Evidence Based Medicine: What it is and what it isn't 显示文摘 | David L Sackett William M C Rosenberg J Muir Gary et al | 1996 | British Medical Journal1996，312，： | 1 |
| 13 | Software for Measuring Root Characters from Digital Images 显示文摘 | Keith TI Gary AL | 2001 | Agronomy Journal2001，93，： | 1 |
| 14 | Ultraviolet Exposure and Vitamin D Synthesis in a Sun-Dwelling and a Shade-Dwelling Species of Anolis :Are There Adaptations for Lower Ultraviolet B and Dietary Vitamin D3 Availability in the Shade 显示文摘 | Gary W Ferguson William H Gehrmann Kristopher B Karsten el al | 2005 | Physiological and Biochemical Zoology2005，78，2： | 1 |
| 15 | Screening,prevention and treatment of cervical cancer-a global and regional generalized cost-effectiveness analysis显示文摘 | Gary Michael Ginsberg Tessa Tan-Torres Edejer Jeremy AL | 2009 | Vaccine2009，27，43： | 1 |
| 16 | LAMIVUDINE FOR HEPATITIS B IN LIVER TRANSPLANTATION: A Single-Center Experience显示文摘 | Geeta Malkan Mark S. Cattral Atul Humar Hamad Al Asghar Paul D. Greig Alan W. Hemming Gary A. Levy Les B. Lilly | 2000 | Transplantation2000，，7： | 1 |
| 17 | Aromatic hydrogen bond in sequence-specific protein DNA recognition显示文摘 | Parinson Gary unaseera Angelo ojtechovsy JaroslavL t al | 1996 | Nat Struct Biol1996，3，10： | 1 |
| 18 | Carotid artery stenting: technical considerations显示文摘 | Jiri J V Gary S R Nadim AL M | 2000 | Am J Neuroradiol2000，21，： | 1 |
| 19 | The definition and classification of dry eye disease: report of the definition and classification subcommittee of the international dry eye work shop (2007) 显示文摘 | Michael AL Baudouin C Gary NF | 2007 | Oeul Surf2007，5，2： | 1 |
| 20 | Radioembolisation for liver metastases: Results from a prospective 151 patient multi-institutional phase II study显示文摘 | Al B. Benson Jean-Francois Geschwind Mary F. Mulcahy William Rilling Gary Siskin Greg Wiseman James Cunningham Bonny Houghton Mason Ross Khairuddin Memon James Andrews Chad J. Fleming Joseph Herman Halla Nimeiri Robert J. Lewandowski Riad Salem | 2013 | European Journal of Cancer2013，，： | 1 |
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