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| 1 | The Hallmarks of Aging显示文摘 | Carlos López-Otín Maria A. Blasco Linda Partridge Manuel Serrano Guido Kroemer | 2013 | Cell2013，，6： | 5 |
| 2 | 22-gauge core vs 22-gauge aspiration needle for endoscopic ultrasound-guided sampling of abdominal masses显示文摘AIM To compare the aspiration needle(AN) and core biopsy needle(PC) in endoscopic ultrasound-guided fine needle aspiration(EUS-FNA) of abdominal masses.METHODS Consecutive patients referred for EUS-FNA were included in this prospective single-center trial. Each patient underwent a puncture of the lesion with both standard 22-gauge(G) AN(Echo Tip Ultra; Cook Medical, Bloomington, Indiana, United States) and the novel 22 G PC(Echo Tip Pro Core; Cook Medical, Bloomington, Indiana, United States) in a randomized fashion; histology was attempted in the PC group only. The main study endpoint was the overall diagnostic accuracy, including the contribution of histology to the final diagnosis. Secondary outcome measures included material adequacy, number of needle passes, and complications.RESULTS Fifty six consecutive patients(29 men; mean age 68 years) with pancreatic lesions(n = 38), lymphadenopathy(n = 13), submucosal tumors(n = 4), or others lesions(n = 1) underwent EUS-FNA using both of the needles in a randomized order. AN and PC reached similar overall results for diagnostic accuracy(AN: 88.9 vs PC: 96.1, P = 0.25), specimen adequacy(AN: 96.4% vs PC: 91.1%, P = 0.38), mean number of passes(AN: 1.5 vs PC: 1.7, P = 0.14), mean cellularity score(AN: 1.7 vs PC: 1.1, P = 0.058), and complications(none). A diagnosis on the basis of histology was achieved in the PC group in 36(64.3%) patients, and in 2 of those as the sole modality. In patients with available histology the mean cellularity score was higher for AN(AN: 1.7 vs PC: 1.0, P = 0.034); no other differences were of statistical significance.CONCLUSION Both needles achieved high overall diagnostic yields and similar performance characteristics for cytological diagnosis; histological analysis was only possible in 2/3 of cases with the new needle. | William Sterlacci Athanasios D Sioulas Lothar Veits Pervin G?nüllü Guido Schachschal Stefan Groth Mario Anders Christos K Kontos Theodoros Topalidis Andrea Hinsch Michael Vieth Thomas R?sch Ulrike W Denzer | 2016 | World Journal of Gastroenterology2016，22，39： | 2 |
| 3 | 幽门螺杆菌感染的治疗显示文摘 | Wink A de Boer Guido N J Tytgat 游晓萍 姚炜 | 2001 | 英国医学杂志中文版2001，4，3： | 2 |
| 4 | Characterization of flavonoids in cranberry (Vaccinium macrocarpon) powder显示文摘 | VVEDENSKAYA I O ROSEN R T GUIDO J E RUSSELL D J MILLS K A VORSA N | 2004 | Journal of Agricultural and Food Chemistry2004，52，： | 1 |
| 5 | New views on the pathogenesis of high-grade pelvic serous carcinoma with suggestions for advancing future research显示文摘 | Sherman ME Guido R Wentzensen N | 2012 | Gynecol Oncol2012，127，3： | 1 |
| 6 | Exercise sustains the hallmarks of health显示文摘Exercise has long been known for its active role in improving physical fitness and sustaining health.Regular moderate-intensity exercise improves all aspects of human health and is widely accepted as a preventative and therapeutic strategy for various diseases.It is well-documented that exercise maintains and restores homeostasis at the organismal,tissue,cellular,and molecular levels to stimulate positive physiological adaptations that consequently protect against various pathological conditions.Here we mainly summarize how moderate-intensity exercise affects the major hallmarks of health,including the integrity of barriers,containment of local perturbations,recycling and turnover,integration of circuitries,rhythmic oscillations,homeostatic resilience,hormetic regulation,as well as repair and regeneration.Furthermore,we summarize the current understanding of the mechanisms responsible for beneficial adaptations in response to exercise.This review aimed at providing a comprehensive summary of the vital biological mechanisms through which moderate-intensity exercise maintains health and opens a window for its application in other health interventions.We hope that continuing investigation in this field will further increase our understanding of the processes involved in the positive role of moderate-intensity exercise and thus get us closer to the identification of new therapeutics that improve quality of life. | Yan Qiu Benjamin Fernández-García H.Immo Lehmann Guoping Li Guido Kroemer Carlos López-Otín Junjie Xiao | 2023 | Journal of Sport and Health Science2023，12，1： | 1 |
| 7 | Are Therapeutic Human Mesenchymal Stromal Cells Compatible with Human Blood?显示文摘 | Guido Moll Ida Rasmusson‐Duprez Lena von Bahr Anne‐Marie Connolly‐Andersen Graciela Elgue Lillemor Funke Osama A. Hamad Helena L?nnies Peetra U. Magnusson Javier Sanchez Yuji Teramura Kristina Nilsson‐Ekdahl Olle Ringdén Olle Korsgren Bo Nilsson Katarina | 2012 | STEM CELLS2012，，7： | 1 |
| 8 | Lack of clinical AIDS in SIV-infected sooty mangabeys with significant CD4^sup +^ T cell loss is associated with double-negative T cells显示文摘 | Milush Jeffrey M Mir Kiran D Sundaravaradan Vasudha Gordon Shari N Engram Jessica Cano Christopher A Reeves Jacqueline F Anton Elizabeth O’Neill Eduardo Butler Eboneé Hancock Kathy Cole Kelly S Brenchley Jason M Else James G Silvestri Guido | 2011 | Journal of Clinical Investigation2011，，3： | 1 |
| 9 | Genetics and electrophoretic karyotyping of wild-type and astaxanthin mutant strains of Phaffia rhodozyma显示文摘 | Víctor Cifuentes Germán Hermosilla Claudio Martínez Ruben León Guido Pincheira Antonio Jiménez | 1997 | Antonie van Leeuwenhoek1997，，2： | 1 |
| 10 | Outcome of hyperleukocytic adult acute myeloid leukaemia:A single-center retrospective study and review of literature显示文摘 | GUIDO N MICHELE N ALESSANDRA T | 2008 | Leukemia Res2008，32，： | 1 |
| 11 | Flavonoida from Hypericum perforatum Show Antidepressant activity in the Forced Swimming Test显示文摘 | Veronika Butterweck Guido J Adolf N | 2000 | PlantaMed2000，66，： | 1 |
| 12 | The 10 × ' 20 Initiative: pursuing a global commitment to develop 10 new antibacterial drugs by 2020显示文摘 | Gilbert D N Guidos R J Boucher H W | 2010 | Clin Infect Dis2010，50，8： | 1 |
| 13 | Laser diode self-mixing technique for sensing applications 显示文摘 | Guido Giuliani M N Silvano Donati Thierry Bosch | 2002 | J Opt A- Pure Appl Op2002，4，： | 1 |
| 14 | Effect of dielectric encapsulation and As overpressure on Al-Ga interdiffusion in Alx Ga1-x As quantum-well heterostructures显示文摘 | Guido L J Holonyak Jr N | 1989 | J Appl Phys1989，55，6： | 1 |
| 15 | Finding the most vital node of a shortest path显示文摘 | ENRICO N GUIDO P PETER W | 2003 | Theoretical Computer Science2003，，1： | 1 |
| 16 | An early development of the nonenal potential in the malting process显示文摘 | Guido L F Boivin P Benismail N | 2005 | Eur Food Res Technol2005，220，2： | 1 |
| 17 | Prognostic role of heart rate variability in patients with a recent acute myocardial infarction显示文摘 | Lanza GA Guido V Galeazzi N | 1998 | Am J Cardiol1998，82，： | 1 |
| 18 | Synthesis of poly, a new plasma expander 显示文摘 | PAOLO N GUIDO A | 1973 | Journal of Medicinal Chemistry1973，16，8： | 1 |
| 19 | Effects of interferon plus ribavirin treatment on NF-kappaB,TGF-betal,and metalloproteinase activity in chronic hepatitis C显示文摘 | Guido M De Franceschi L Olivari N | 2006 | Mod Pathol2006，19，8： | 1 |
| 20 | Automated identification of installed malicious Android applications显示文摘 | Guido D M Ondricek J K Grover J N | 2013 | Digital Investigation2013，，10： | 1 |
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